Olig bHLH proteins interact with homeodomain proteins to regulate cell fate acquisition in progenitors of the ventral neural tube

Current Biology

Volumn 11, Issue 18, 2001, Pages 1413-1420

  Sun, Tao ^a   Echelard, Yann ^b   Lu, Richard ^a   Yuk, Dong in ^a   Kaing, Sovann ^a   Stiles, Charles D ^a   Rowitch, David H ^a,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b Genzyme Transgenics Corporation   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; ERINACEIDAE; MUS MUSCULUS;

EID: 0035908998     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(01)00441-9     Document Type: Article

References (34)

1. Diversity and pattern in the developing spinal cord
2. Neuronal specification in the spinal cord: Inductive signals and transcriptional codes
3. Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling
4. A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube
5. Ventral neural patterning by Nkx homeobox genes: Nkx6.1 controls somatic motor neuron and ventral interneuron fates
6. Stem cells and pattern formation in the nervous system. The possible versus the actual
7. Neural patterning: The role of Nkx genes in the ventral spinal cord
8. Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling
9. Two new members of the murine Sim gene family are transcriptional repressors and show different expression patterns during mouse embryogenesis
10. Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons
11. Identification of neurogenin, a vertebrate neuronal determination gene
12. Math1 is essential for genesis of cerebellar granule neurons
13. The bHLH protein NEUROGENIN 2 is a determination factor for epibranchial placode-derived sensory neurons
14. Neural bHLH genes control the neuronal versus glial fate decision in cortical progenitors
15. Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanisms
16. Restricted expression of a novel murine atonal-related bHLH protein in undifferentiated neural precursors
17. Neurogenins, a novel family of atonal-related bHLH transcription factors, are putative mammalian neuronal determination genes that reveal progenitor cell heterogeneity in the developing CNS and PNS
18. Mash1 and neurogenin1 expression patterns define complementary domains of neuroepithelium in the developing CNS and are correlated with regions expressing notch ligands
19. Sonic hedgehog-regulated oligodendrocyte lineage genes encoding bHLH proteins in the mammalian central nervous system
20. Identification of a novel family of oligodendrocyte lineage-specific basic helix-loop-helix transcription factors
21. Dynamic expression of basic helix-loop-helix Olig family members: Implication of Olig2 in neuron and oligodendrocyte differentiation and identification of a new member, Olig3
22. Oligodendrocyte population dynamics and the role of PDGF in vivo
23. Multiple spatially specific enhancers are required to reconstruct the pattern of Hox-2.6 gene expression
24. Evidence for a mitogenic effect of Wnt-1 in the developing mammalian central nervous system
25. Genetic mosaicism in the generation of transgenic animals: Generation and use
26. Selective expression of Nkx-2.2 transcription factor in chicken oligodendrocyte progenitors and implications for the embryonic origin of oligodendrocytes
27. Distinct sites of origin of oligodendrocytes and somatic motoneurons in the chick spinal cord: Oligodendrocytes arise from Nkx2.2-expressing progenitors by a Shh-dependent mechanism
28. Chick sox10, a transcription factor expressed in both early neural crest cells and central nervous system
29. Rab23 is an essential negative regulator of the mouse Sonic hedgehog signalling pathway
30. Control of oligodendrocyte differentiation by the Nkx-2.2 homeodomain transcription factor
31. Groucho-mediated transcriptional repression establishes progenitor cell pattern and neuronal fate in the ventral neural tube
32. Specific protein-protein interaction between basic helix-loop-helix transcription factors and homeoproteins of the Pitx family
33. Timing cell-cycle exit and differentiation in oligodendrocyte development
34. Cis-acting regulatory sequences governing Wnt-1 expression in the developing mouse CNS