Engraftable human neural stem cells respond to developmental cues, replace neurons, and express foreign genes

Nature Biotechnology

Volumn 16, Issue 11, 1998, Pages 1033-1039

  Flax, Jonathan D ^a   Aurora, Sanjay ^a   Yang, Chunhua ^a   Simonin, Clemence ^a   Wills, Ann Marie ^a   Billinghurst, Lori L ^a   Jendoubi, Moncef ^b   Sidman, Richard L ^c   Wolfe, John H ^d   Kim, Seung U ^e   Snyder, Evan Y ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b NATIONAL EYE INSTITUTE   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Cell therapy; Differentiation; Gene therapy; Progenitor cell; Tay Sachs disease; Transplanation

Indexed keywords

ANIMAL TISSUE; ARTICLE; CELL RENEWAL; CONTROLLED STUDY; CRYOPRESERVATION; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER; GENETIC ENGINEERING; HUMAN; HUMAN CELL; MOLECULAR CLONING; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; STEM CELL TRANSPLANTATION; TAY SACHS DISEASE; TELENCEPHALON; TRANSGENE;

ANIMALS; ANIMALS, NEWBORN; BETA-N-ACETYLHEXOSAMINIDASE; BIOTECHNOLOGY; BRAIN; BRAIN TISSUE TRANSPLANTATION; CELL MOVEMENT; CELLS, CULTURED; FETAL TISSUE TRANSPLANTATION; GENE THERAPY; GENETIC ENGINEERING; HUMANS; MICE; NEURONS; STEM CELL TRANSPLANTATION; STEM CELLS; TAY-SACHS DISEASE; TRANSPLANTATION, HETEROLOGOUS;

ANIMALIA; GILA; RODENTIA;

EID: 0031771599     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/3473     Document Type: Article

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