An evaluation of the cytochrome P450 inhibition potential of selected pesticides in human hepatic microsomes

Journal of Environmental Science and Health - Part B Pesticides, Food Contaminants, and Agricultural Wastes

Volumn 44, Issue 6, 2009, Pages 553-563

  Abass, Khaled ^a   Turpeinen, Miia ^a   Pelkonen, Olavi ^a  

^a UNIVERSITY OF OULU   (Finland)

Author keywords

Human liver microsomes; In vitro; Inhibitory interactions; P450; Pesticides

Indexed keywords

ABAMECTIN; ALPHA-CYPERMETHRIN; ATRAZINES; CARBARYL; CARBENDAZIM; CHLORPYRIFOS; CYPERMETHRINS; CYTOCHROME P450; DELTAMETHRIN; FENITROTHION; FENVALERATE; GLYPHOSATES; HUMAN LIVER MICROSOMES; IC50 VALUE; IN VITRO; INHIBITORY INTERACTIONS; ISOPROTURON; LAMBDA-CYHALOTHRIN; OCCUPATIONAL EXPOSURE; ORGANOPHOSPHORUS INSECTICIDES; P450; POTENT INHIBITION; POTENT INHIBITOR; PROFENOFOS; PYRETHROIDS; XENOBIOTIC-METABOLIZING ENZYMES;

AGRICULTURAL CHEMICALS; ESTERS; HERBICIDES; LIVER;

INSECTICIDES;

CYP2C8 PROTEIN, HUMAN; CYP2C9 PROTEIN, HUMAN; CYTOCHROME P450; CYTOCHROME P450 2D6; PESTICIDE; UNSPECIFIC MONOOXYGENASE;

CYTOCHROME; CYTOLOGY; ENZYME ACTIVITY; HEALTH IMPACT; METABOLISM; OCCUPATIONAL EXPOSURE; ORGANOPHOSPHATE; PESTICIDE; PUBLIC HEALTH;

ARTICLE; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; EVALUATION; HUMAN; IC 50; LIVER MICROSOME; METABOLISM;

ARYL HYDROCARBON HYDROXYLASES; CYTOCHROME P-450 CYP2D6; CYTOCHROME P-450 ENZYME SYSTEM; HUMANS; INHIBITORY CONCENTRATION 50; MICROSOMES, LIVER; PESTICIDES;

EID: 70449361924     PISSN: 03601234     EISSN: 15324109     Source Type: Journal    
DOI: 10.1080/03601230902997766     Document Type: Article

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