Molecular non-genetic biomarkers of effect related to methyl thiophanate cocarcinogenesis: Organ- and sex-specific cytochrome P450 induction in the rat

Cancer Letters

Volumn 135, Issue 2, 1999, Pages 203-213

  Paolini, M ^a   Pozzetti, L ^a   Perocco, P ^b   Mazzullo, M ^b   Cantelli Forti, G ^a,c  

^a Biochemical Toxicology Unit   (Italy)

^b Institute of Cancerology   (Italy)

^c University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Cytochrome P450 induction; Fungicides; Methyl thiophanate; Pesticides

Indexed keywords

BIOCHEMICAL MARKER; CYTOCHROME P450 ISOENZYME; DIMETHYLNITROSAMINE DEMETHYLASE; ETHOXYRESORUFIN DEETHYLASE; OXIDOREDUCTASE; PENTOXYRESORUFIN DEALKYLASE; PHENACETIN O DEETHYLASE; THIOPHANATE METHYL;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COCARCINOGENESIS; CONTROLLED STUDY; ENZYME INDUCTION; FEMALE; KIDNEY MICROSOME; LIVER MICROSOME; LUNG; MALE; NONHUMAN; ORGAN WEIGHT; PRIORITY JOURNAL; RAT; SEX DIFFERENCE;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; COCARCINOGENESIS; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 CYP2B1; CYTOCHROME P-450 CYP2E1; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INDUCTION; FEMALE; FUNGICIDES, INDUSTRIAL; KIDNEY; LUNG; MALE; MICROSOMES; MICROSOMES, LIVER; ORGAN SPECIFICITY; OXIDOREDUCTASES, N-DEMETHYLATING; RATS; RATS, SPRAGUE-DAWLEY; SEX FACTORS; THIOPHANATE;

EID: 0033057737     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(98)00298-5     Document Type: Article

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