-
1
-
-
0344987881
-
A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome
-
Cools J, DeAngelo DJ, Gotlib J, et al. A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome. N Engl J Med 2003;348:1201-14.
-
(2003)
N Engl J Med
, vol.348
, pp. 1201-1214
-
-
Cools, J.1
DeAngelo, D.J.2
Gotlib, J.3
-
2
-
-
0035810147
-
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
-
Druker BJ, Talpaz M, Resta DJ, et al. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med 2001;344:1031-7.
-
(2001)
N Engl J Med
, vol.344
, pp. 1031-1037
-
-
Druker, B.J.1
Talpaz, M.2
Resta, D.J.3
-
3
-
-
0035810142
-
Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome
-
Druker BJ, Sawyers CL, Kantarjian H, et al. Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome. N Engl J Med 2001;344:1038-42.
-
(2001)
N Engl J Med
, vol.344
, pp. 1038-1042
-
-
Druker, B.J.1
Sawyers, C.L.2
Kantarjian, H.3
-
4
-
-
0037103624
-
Response to imatinib mesylate in patients with chronic myeloproliferative diseases with rearrangements of the platelet-derived growth factor receptor beta
-
Apperley JF, Gardembas M, Melo JV, et al. Response to imatinib mesylate in patients with chronic myeloproliferative diseases with rearrangements of the platelet-derived growth factor receptor beta. N Engl J Med 2002;347:481-7.
-
(2002)
N Engl J Med
, vol.347
, pp. 481-487
-
-
Apperley, J.F.1
Gardembas, M.2
Melo, J.V.3
-
5
-
-
0242670019
-
PDGFRA activating mutations in gastrointestinal stromal tumors
-
Heinrich MC, Corless CL, Duensing A, et al. PDGFRA activating mutations in gastrointestinal stromal tumors. Science 2003;299:708-10.
-
(2003)
Science
, vol.299
, pp. 708-710
-
-
Heinrich, M.C.1
Corless, C.L.2
Duensing, A.3
-
6
-
-
0036727124
-
Molecular targeting of platelet-derived growth factor B by imatinib mesylate in a patient with metastatic dermatofibrosarcoma protuberans
-
Rubin BP, Schuetze SM, Eary JF, et al. Molecular targeting of platelet-derived growth factor B by imatinib mesylate in a patient with metastatic dermatofibrosarcoma protuberans. J Clin Oncol 2002;20:3586-91.
-
(2002)
J Clin Oncol
, vol.20
, pp. 3586-3591
-
-
Rubin, B.P.1
Schuetze, S.M.2
Eary, J.F.3
-
7
-
-
0037103424
-
Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors
-
Demetri GD, von Mehren M, Blanke CD, et al. Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors. N Engl J Med 2002;347:472-80.
-
(2002)
N Engl J Med
, vol.347
, pp. 472-480
-
-
Demetri, G.D.1
Von Mehren, M.2
Blanke, C.D.3
-
8
-
-
0028137446
-
Signal transduction by the PDGF receptors
-
Claesson-Welsh L. Signal transduction by the PDGF receptors. Prog Growth Factor Res 1994;5:37-54.
-
(1994)
Prog Growth Factor Res
, vol.5
, pp. 37-54
-
-
Claesson-Welsh, L.1
-
9
-
-
0016430025
-
The hypereosinophilic syndrome: Analysis of fourteen cases with review of the literature
-
Chusid MJ, Dale DC, West BC, Wolff SM. The hypereosinophilic syndrome: analysis of fourteen cases with review of the literature. Medicine 1975;54:1-27.
-
(1975)
Medicine
, vol.54
, pp. 1-27
-
-
Chusid, M.J.1
Dale, D.C.2
West, B.C.3
Wolff, S.M.4
-
10
-
-
0002884977
-
Chronic eosinophilic leukaemia and the hypereosinophilic syndrome
-
Jaffe ES, Harris NL, Stein H, Vardiman JW, editors. Lyon: IARC Press
-
Bain B, Pierre R, Imbert M, Vardiman JW, Brunning RD, Flandrin G. Chronic eosinophilic leukaemia and the hypereosinophilic syndrome. In: Jaffe ES, Harris NL, Stein H, Vardiman JW, editors. World Health Organization Classification of Tumours: Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues. Lyon: IARC Press; 2001. p. 29-31.
-
(2001)
World Health Organization Classification of Tumours: Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues
, pp. 29-31
-
-
Bain, B.1
Pierre, R.2
Imbert, M.3
Vardiman, J.W.4
Brunning, R.D.5
Flandrin, G.6
-
11
-
-
18744423188
-
Myelodysplastic syndrome with hypereosinophilia and a nonrandom chromosomal abnormality dic(1;7): Confirmation of eosinophil clonal involvement by fluorescence in situ hybridization
-
Forrest DL, Horsman DE, Jensen CL, et al. Myelodysplastic syndrome with hypereosinophilia and a nonrandom chromosomal abnormality dic(1;7): confirmation of eosinophil clonal involvement by fluorescence in situ hybridization. Cancer Genet Cytogenet 1998;107:65-8.
-
(1998)
Cancer Genet Cytogenet
, vol.107
, pp. 65-68
-
-
Forrest, D.L.1
Horsman, D.E.2
Jensen, C.L.3
-
12
-
-
0033104707
-
Clonality of isolated eosinophils in the hypereosinophilic syndrome
-
Chang HW, Leong KH, Koh DR, Lee SH. Clonality of isolated eosinophils in the hypereosinophilic syndrome. Blood 1999;93:1651-7.
-
(1999)
Blood
, vol.93
, pp. 1651-1657
-
-
Chang, H.W.1
Leong, K.H.2
Koh, D.R.3
Lee, S.H.4
-
13
-
-
0032574902
-
Eosinophilia
-
Rothenberg ME. Eosinophilia. N Engl J Med 1998;338:1592-600.
-
(1998)
N Engl J Med
, vol.338
, pp. 1592-1600
-
-
Rothenberg, M.E.1
-
14
-
-
0038315443
-
The hypereosinophilic syndrome revisited
-
Roufosse F, Cogan E, Goldman M. The hypereosinophilic syndrome revisited. Annu Rev Med 2003;54:169-84.
-
(2003)
Annu Rev Med
, vol.54
, pp. 169-184
-
-
Roufosse, F.1
Cogan, E.2
Goldman, M.3
-
15
-
-
0038792233
-
Elevated serum tryptase levels identify a subset of patients with a myeloproliferative variant of idiopathic hypereosinophilic syndrome associated with tissue fibrosis, poor prognosis, and imatinib responsiveness
-
Klion AD, Noel P, Akin C, et al. Elevated serum tryptase levels identify a subset of patients with a myeloproliferative variant of idiopathic hypereosinophilic syndrome associated with tissue fibrosis, poor prognosis, and imatinib responsiveness. Blood 2003;101:4660-6.
-
(2003)
Blood
, vol.101
, pp. 4660-4666
-
-
Klion, A.D.1
Noel, P.2
Akin, C.3
-
16
-
-
0042784918
-
Clonal Th2 lymphocytes in patients with the idiopathic hypereosinophilic syndrome
-
Roufosse F, Schandene L, Sibille C, et al. Clonal Th2 lymphocytes in patients with the idiopathic hypereosinophilic syndrome. Br J Haematol 2000;109:540-8.
-
(2000)
Br J Haematol
, vol.109
, pp. 540-548
-
-
Roufosse, F.1
Schandene, L.2
Sibille, C.3
-
17
-
-
0344809973
-
Abnormal clones of T cells producing interleukin-5 in idiopathic hypereosinophilia
-
Simon HU, Plotz SG, Dummer R, Blaser K. Abnormal clones of T cells producing interleukin-5 in idiopathic hypereosinophilia. N Eng J Med 1999;341:1112-20.
-
(1999)
N Eng J Med
, vol.341
, pp. 1112-1120
-
-
Simon, H.U.1
Plotz, S.G.2
Dummer, R.3
Blaser, K.4
-
18
-
-
12644276390
-
Clonal eosinophilic disorders and the hypereosinophilic syndrome
-
Brito-Babapulle F. Clonal eosinophilic disorders and the hypereosinophilic syndrome. Blood Rev 1997;11:129-45.
-
(1997)
Blood Rev
, vol.11
, pp. 129-145
-
-
Brito-Babapulle, F.1
-
19
-
-
0028323393
-
The idiopathic hypereosinophilic syndrome
-
Weller PF, Bubley GJ. The idiopathic hypereosinophilic syndrome. Blood 1994;83:2759-79.
-
(1994)
Blood
, vol.83
, pp. 2759-2779
-
-
Weller, P.F.1
Bubley, G.J.2
-
20
-
-
0038487039
-
Cytogenetic and molecular genetic aspects of eosinophilic leukaemias
-
Bain BJ. Cytogenetic and molecular genetic aspects of eosinophilic leukaemias. Br J Haematol 2003;122:173-9.
-
(2003)
Br J Haematol
, vol.122
, pp. 173-179
-
-
Bain, B.J.1
-
21
-
-
0020550724
-
Association of inversion 16 with abnormal marrow eosinophils in acute myelomonocytic leukemia
-
Le Beau MM, Larson RA, Bitter MA, Vardiman JW, Golomb HM, Rowley JD. Association of inversion 16 with abnormal marrow eosinophils in acute myelomonocytic leukemia. N Eng J Med 1983;309:630-6.
-
(1983)
N Eng J Med
, vol.309
, pp. 630-636
-
-
Le Beau, M.M.1
Larson, R.A.2
Bitter, M.A.3
Vardiman, J.W.4
Golomb, H.M.5
Rowley, J.D.6
-
22
-
-
0021329244
-
8;21 Translocation in acute granulocytic leukemia: Cytological cytochemical, and clinical features
-
Swirsky DM, Li YS, Matthews JG, Flemans RJ, Rees JKH, Hayhoe FGJ. 8;21 translocation in acute granulocytic leukemia: cytological cytochemical, and clinical features. Br J Haematol 1984;56:199-213.
-
(1984)
Br J Haematol
, vol.56
, pp. 199-213
-
-
Swirsky, D.M.1
Li, Y.S.2
Matthews, J.G.3
Flemans, R.J.4
Rees, J.K.H.5
Hayhoe, F.G.J.6
-
23
-
-
0029131922
-
Steroid-responsive pulmonary disorders associated with myelodysplastic syndromes with der(1q;7p) chromosomal abnormality
-
Matsushima T, Murakami H, Kim K, et al. Steroid-responsive pulmonary disorders associated with myelodysplastic syndromes with der(1q;7p) chromosomal abnormality. Am J Hematol 1995;50:110-5.
-
(1995)
Am J Hematol
, vol.50
, pp. 110-115
-
-
Matsushima, T.1
Murakami, H.2
Kim, K.3
-
24
-
-
0036202064
-
The 8p11 myeloproliferative syndrome: A distinct clinical entity caused by constitutive activation of FGFR1
-
Macdonald D, Reiter A, Cross NC. The 8p11 myeloproliferative syndrome: a distinct clinical entity caused by constitutive activation of FGFR1. Acta Haematol 2002;107:101-7.
-
(2002)
Acta Haematol
, vol.107
, pp. 101-107
-
-
Macdonald, D.1
Reiter, A.2
Cross, N.C.3
-
25
-
-
0033558253
-
The t(6;8)(q27;p11) translocation in a stem cell myeloproliferative disorder fuses a novel gene, FOP, to fibroblast growth factor receptor 1
-
Popovici C, Zhang B, Gregoire MJ, et al. The t(6;8)(q27;p11) translocation in a stem cell myeloproliferative disorder fuses a novel gene, FOP, to fibroblast growth factor receptor 1. Blood 1999;93:1381-9.
-
(1999)
Blood
, vol.93
, pp. 1381-1389
-
-
Popovici, C.1
Zhang, B.2
Gregoire, M.J.3
-
26
-
-
0034161335
-
FGFR1 is fused to the centrosome-associated protein CEP110 in the 8p12 stem cell myeloproliferative disorder with t(8;9)(p12;q33)
-
Guasch G, Mack GJ, Popovici C, et al. FGFR1 is fused to the centrosome-associated protein CEP110 in the 8p12 stem cell myeloproliferative disorder with t(8;9)(p12;q33). Blood 2000;95:1788-96.
-
(2000)
Blood
, vol.95
, pp. 1788-1796
-
-
Guasch, G.1
Mack, G.J.2
Popovici, C.3
-
27
-
-
0032510791
-
Fibroblast growth factor receptor 1 is fused to FIM in stem-cell myeloproliferative disorder with t(8;13)
-
Popovici C, Adelaide J, Ollendorff V, et al. Fibroblast growth factor receptor 1 is fused to FIM in stem-cell myeloproliferative disorder with t(8;13). Proc Natl Acad Sci USA 1998;95:5712-7.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 5712-5717
-
-
Popovici, C.1
Adelaide, J.2
Ollendorff, V.3
-
28
-
-
0035895067
-
The t(8;22) in chronic myeloid leukemia fuses BCR to FGFR1: Transforming activity and specific inhibition of FGFR1 fusion proteins
-
Demiroglu A, Steer EJ, Heath C, et al. The t(8;22) in chronic myeloid leukemia fuses BCR to FGFR1: transforming activity and specific inhibition of FGFR1 fusion proteins. Blood 2001;98:3778-83.
-
(2001)
Blood
, vol.98
, pp. 3778-3783
-
-
Demiroglu, A.1
Steer, E.J.2
Heath, C.3
-
29
-
-
0037216062
-
Endogenous retroviral sequence is fused to FGFR1 kinase in the 8p12 stem-cell myeloproliferative disorder with t(8;19)(p12;q13.3)
-
Guasch G, Popovici C, Mugneret F, et al. Endogenous retroviral sequence is fused to FGFR1 kinase in the 8p12 stem-cell myeloproliferative disorder with t(8;19)(p12;q13.3). Blood 2003;101:286-8.
-
(2003)
Blood
, vol.101
, pp. 286-288
-
-
Guasch, G.1
Popovici, C.2
Mugneret, F.3
-
30
-
-
0036202529
-
Myeloproliferative disorders with translocations of chromosome 5q31-35: Role of the platelet-derived growth factor receptor beta
-
Steer EJ, Cross NC. Myeloproliferative disorders with translocations of chromosome 5q31-35: role of the platelet-derived growth factor receptor beta. Acta Haematol 2002;107:113-22.
-
(2002)
Acta Haematol
, vol.107
, pp. 113-122
-
-
Steer, E.J.1
Cross, N.C.2
-
31
-
-
0346186282
-
Novel translocations that disrupt the platelet-derived growth factor receptor beta (PDGFRB) gene in BCR-ABL-negative chronic myeloproliferative disorders
-
Baxter EJ, Kulkarni S, Vizmanos JL, et al. Novel translocations that disrupt the platelet-derived growth factor receptor beta (PDGFRB) gene in BCR-ABL-negative chronic myeloproliferative disorders. Br J Haematol 2003;120:251-6.
-
(2003)
Br J Haematol
, vol.120
, pp. 251-256
-
-
Baxter, E.J.1
Kulkarni, S.2
Vizmanos, J.L.3
-
32
-
-
0028224348
-
Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation
-
Golub TR, Barker GF, Lovett M, Gilliland DG. Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation. Cell 1994;77:307-16.
-
(1994)
Cell
, vol.77
, pp. 307-316
-
-
Golub, T.R.1
Barker, G.F.2
Lovett, M.3
Gilliland, D.G.4
-
33
-
-
0028356630
-
Eosinophilic leukemia with a t(2;5)(p23;q35) translocation
-
Sato H, Danbara M, Tamura M, Morita M. Eosinophilic leukemia with a t(2;5)(p23;q35) translocation. Br J Haematol 1994;87:404-6.
-
(1994)
Br J Haematol
, vol.87
, pp. 404-406
-
-
Sato, H.1
Danbara, M.2
Tamura, M.3
Morita, M.4
-
34
-
-
0028237102
-
A case of myelodysplasia with eosinophilia having a translocation t(5;12)(q31;q13) restricted to myeloid cells but not involving eosinophils
-
Jani K, Kempski HM, Reeves BR. A case of myelodysplasia with eosinophilia having a translocation t(5;12)(q31;q13) restricted to myeloid cells but not involving eosinophils. Br J Haematol 1994;87:57-60.
-
(1994)
Br J Haematol
, vol.87
, pp. 57-60
-
-
Jani, K.1
Kempski, H.M.2
Reeves, B.R.3
-
35
-
-
0025361918
-
Activation of the interleukin-3 gene by chromosome translocation in acute lymphoblastic leukemia with eosinophilia
-
Meeker TC, Hardy D, Willman C, Hogan T, Abrams J. Activation of the interleukin-3 gene by chromosome translocation in acute lymphoblastic leukemia with eosinophilia. Blood 1990;76:285-9.
-
(1990)
Blood
, vol.76
, pp. 285-289
-
-
Meeker, T.C.1
Hardy, D.2
Willman, C.3
Hogan, T.4
Abrams, J.5
-
36
-
-
0037228313
-
T(5;9)(q11;q34): A novel familial translocation involving Abelson oncogene and association with hypereosinophilia
-
Bakhshi S, Hamre M, Mohamed AN, Feldman G, Ravindranath Y. t(5;9)(q11;q34): a novel familial translocation involving Abelson oncogene and association with hypereosinophilia. J Pediatr Hematol Oncol 2003;25:82-4.
-
(2003)
J Pediatr Hematol Oncol
, vol.25
, pp. 82-84
-
-
Bakhshi, S.1
Hamre, M.2
Mohamed, A.N.3
Feldman, G.4
Ravindranath, Y.5
-
37
-
-
0030886435
-
2-Chlorodeoxyadenosine therapy for idiopathic hypereosinophilic syndrome
-
Ueno NT, Zhao S, Robertson LE, Consoli U, Andreeff M. 2-Chlorodeoxyadenosine therapy for idiopathic hypereosinophilic syndrome. Leukemia 1997;11:1386-90.
-
(1997)
Leukemia
, vol.11
, pp. 1386-1390
-
-
Ueno, N.T.1
Zhao, S.2
Robertson, L.E.3
Consoli, U.4
Andreeff, M.5
-
38
-
-
0025737818
-
Cyclosporin for hypereosinophilic syndrome
-
Zabel P, Schlaak M. Cyclosporin for hypereosinophilic syndrome. Ann Hematol 1991;62:230-1.
-
(1991)
Ann Hematol
, vol.62
, pp. 230-231
-
-
Zabel, P.1
Schlaak, M.2
-
39
-
-
0031768159
-
Interferon-alpha in the idiopathic hypereosinophilic syndrome: Consideration of five cases
-
Ceretelli S, Capochiani E, Petrini M. Interferon-alpha in the idiopathic hypereosinophilic syndrome: consideration of five cases. Ann Hematol 1998;77:161-4.
-
(1998)
Ann Hematol
, vol.77
, pp. 161-164
-
-
Ceretelli, S.1
Capochiani, E.2
Petrini, M.3
-
40
-
-
0020523189
-
Comparative analysis of the influences of human gamma, alpha and beta interferons on human multipotential (CFU-GEMM), erythroid (BFU-E), and granulocyte-macrophage (CFU-GM) progenitor cells
-
Broxmeyer HE, Lu L, Platzer E, Feit C, Juliano L, Rubin BY. Comparative analysis of the influences of human gamma, alpha and beta interferons on human multipotential (CFU-GEMM), erythroid (BFU-E), and granulocyte-macrophage (CFU-GM) progenitor cells. J Immunol 1983;131:1300-5.
-
(1983)
J Immunol
, vol.131
, pp. 1300-1305
-
-
Broxmeyer, H.E.1
Lu, L.2
Platzer, E.3
Feit, C.4
Juliano, L.5
Rubin, B.Y.6
-
41
-
-
0030040423
-
Recombinant interferon-alpha selectively inhibits the production of interleukin-5 by human CD4+ T cells
-
Schandene L, Del Prete GF, Cogan E, et al. Recombinant interferon-alpha selectively inhibits the production of interleukin-5 by human CD4+ T cells. J Clin Invest 1996;97:309-15.
-
(1996)
J Clin Invest
, vol.97
, pp. 309-315
-
-
Schandene, L.1
Del Prete, G.F.2
Cogan, E.3
-
42
-
-
0029871617
-
Eosinophils express a functional receptor for interferon alpha: Inhibitory role of interferon alpha on the release of mediators
-
Aldebert D, Lamkhioued B, Desaint C, et al. Eosinophils express a functional receptor for interferon alpha: inhibitory role of interferon alpha on the release of mediators. Blood 1996;87:2354-60.
-
(1996)
Blood
, vol.87
, pp. 2354-2360
-
-
Aldebert, D.1
Lamkhioued, B.2
Desaint, C.3
-
43
-
-
0033951762
-
Allogeneic peripheral blood cell transplantation for hypereosinophilic syndrome with myelofibrosis
-
Vazquez L, Caballero D, Canizo CD. Allogeneic peripheral blood cell transplantation for hypereosinophilic syndrome with myelofibrosis. Bone Marrow Transplant 2000;25:217-8.
-
(2000)
Bone Marrow Transplant
, vol.25
, pp. 217-218
-
-
Vazquez, L.1
Caballero, D.2
Canizo, C.D.3
-
44
-
-
10744233716
-
Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia
-
O'Brien SG, Guilhot F, Larson RA, et al. Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia. N Engl J Med 2003;348:994-1004.
-
(2003)
N Engl J Med
, vol.348
, pp. 994-1004
-
-
O'Brien, S.G.1
Guilhot, F.2
Larson, R.A.3
-
45
-
-
0037186915
-
Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia
-
Kantarjian H, Sawyers C, Hochhaus A. Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia. N Engl J Med 2002;346:645-52.
-
(2002)
N Engl J Med
, vol.346
, pp. 645-652
-
-
Kantarjian, H.1
Sawyers, C.2
Hochhaus, A.3
-
46
-
-
0037093092
-
Imatinib induces hematologic and cytogenetic responses with chronic myelogenous leukemia in myeloid blast crisis: Results of a phase II study
-
Sawyers CL, Hochhaus A, Feldman E. Imatinib induces hematologic and cytogenetic responses with chronic myelogenous leukemia in myeloid blast crisis: results of a phase II study. Blood 2002;99:3530-9.
-
(2002)
Blood
, vol.99
, pp. 3530-3539
-
-
Sawyers, C.L.1
Hochhaus, A.2
Feldman, E.3
-
47
-
-
0037085785
-
Imatinib induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia: Results of a phase 2 study
-
Talpaz M, Silver RT, Druker BJ, et al. Imatinib induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia: results of a phase 2 study. Blood 2002;99:1928-37.
-
(2002)
Blood
, vol.99
, pp. 1928-1937
-
-
Talpaz, M.1
Silver, R.T.2
Druker, B.J.3
-
48
-
-
0038024597
-
Clinical decisions for chronic myeloid leukemia in the imatinib era
-
Goldman JM, Martin D, Olavarria E, et al. Clinical decisions for chronic myeloid leukemia in the imatinib era. Semin Hematol 2003;40(Suppl 2):98-103.
-
(2003)
Semin Hematol
, vol.40
, Issue.2 SUPPL.
, pp. 98-103
-
-
Goldman, J.M.1
Martin, D.2
Olavarria, E.3
-
49
-
-
0035800507
-
Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification
-
Gorre ME, Mohammed M, Ellwood K. Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification. Science 2001;293:876-80.
-
(2001)
Science
, vol.293
, pp. 876-880
-
-
Gorre, M.E.1
Mohammed, M.2
Ellwood, K.3
-
50
-
-
0037045583
-
Bcr/abl gene mutations in relation to clinical resistance of Philadelphia-chromosome-positive leukemia to STI571: A prospective study
-
von Bubnoff N, Schneller F, Peschel C, et al. Bcr/abl gene mutations in relation to clinical resistance of Philadelphia-chromosome-positive leukemia to STI571: a prospective study. Lancet 2002;359:487-91.
-
(2002)
Lancet
, vol.359
, pp. 487-491
-
-
Bubnoff, N.1
Schneller, F.2
Peschel, C.3
-
51
-
-
0036566540
-
High frequency of point mutations clustered within the adenosine triphosphate-binding region of BCR/ABL in patients with chronic myeloid leukemia or Ph-positive acute lymphoblastic leukemia who develop imatinib (STI571) resistance
-
Branford S, Rudzki ZM, Walsh S, et al. High frequency of point mutations clustered within the adenosine triphosphate-binding region of BCR/ABL in patients with chronic myeloid leukemia or Ph-positive acute lymphoblastic leukemia who develop imatinib (STI571) resistance. Blood 2002;99:3472-5.
-
(2002)
Blood
, vol.99
, pp. 3472-3475
-
-
Branford, S.1
Rudzki, Z.M.2
Walsh, S.3
-
52
-
-
0036850514
-
Molecular and chromosomal mechanisms of resistance to imatinib (STI571) therapy
-
Hochhaus A, Kreil S, Corbin AS, et al. Molecular and chromosomal mechanisms of resistance to imatinib (STI571) therapy. Leukemia 2002;16:2190-6.
-
(2002)
Leukemia
, vol.16
, pp. 2190-2196
-
-
Hochhaus, A.1
Kreil, S.2
Corbin, A.S.3
-
53
-
-
0034161460
-
Induction of resistance to the Abelson inhibitor STI571 in human leukemia cells through gene amplification
-
Le Coutre P, Tassi E, Varella-Garcia M. Induction of resistance to the Abelson inhibitor STI571 in human leukemia cells through gene amplification. Blood 2000;95:1758-66.
-
(2000)
Blood
, vol.95
, pp. 1758-1766
-
-
Le Coutre, P.1
Tassi, E.2
Varella-Garcia, M.3
-
54
-
-
0034254368
-
Selection and characterization of BCR-ABL positive cell lines with differential sensitivity to the tyrosine kinase inhibitor STI571: Diverse mechanisms of resistance
-
Mahon FX, Deininger MW, Schultheis B, et al. Selection and characterization of BCR-ABL positive cell lines with differential sensitivity to the tyrosine kinase inhibitor STI571: diverse mechanisms of resistance. Blood 2000;96:1070-9.
-
(2000)
Blood
, vol.96
, pp. 1070-1079
-
-
Mahon, F.X.1
Deininger, M.W.2
Schultheis, B.3
-
55
-
-
10744232328
-
Detection of BCR-ABL mutations in patients with CML treated with imatinib is virtually always accompanied by clinical resistance and mutations in the ATP phosphate-binding loop (P-loop) are associated with poor prognosis
-
Branford S, Rudzki Z, Walsh S, et al. Detection of BCR-ABL mutations in patients with CML treated with imatinib is virtually always accompanied by clinical resistance and mutations in the ATP phosphate-binding loop (P-loop) are associated with poor prognosis. Blood 2003;102:276-83.
-
(2003)
Blood
, vol.102
, pp. 276-283
-
-
Branford, S.1
Rudzki, Z.2
Walsh, S.3
-
56
-
-
0037438640
-
BCR-ABL independence and LYN kinase overexpression in chronic myelogenous leukemia cells selected for resistance to STI571
-
Donato NJ, Wu JY, Stapley J, et al. BCR-ABL independence and LYN kinase overexpression in chronic myelogenous leukemia cells selected for resistance to STI571. Blood 2003;101:690-8.
-
(2003)
Blood
, vol.101
, pp. 690-698
-
-
Donato, N.J.1
Wu, J.Y.2
Stapley, J.3
-
57
-
-
4243343870
-
In vivo resistance to Glivec is not consistently associated with resistance with in vitro but may be related to increased MDR-1 expression
-
Deininger M, Leiblein S, Keohler T, et al. In vivo resistance to Glivec is not consistently associated with resistance with in vitro but may be related to increased MDR-1 expression. Blood 2002;98:176b.
-
(2002)
Blood
, vol.98
-
-
Deininger, M.1
Leiblein, S.2
Keohler, T.3
-
58
-
-
0037443754
-
MDR1 gene overexpression confers resistance to imatinib mesylate in leukemia cell line models
-
Mahon FX, Belloc F, Lagarde V, et al. MDR1 gene overexpression confers resistance to imatinib mesylate in leukemia cell line models. Blood 2003;101:2368-73.
-
(2003)
Blood
, vol.101
, pp. 2368-2373
-
-
Mahon, F.X.1
Belloc, F.2
Lagarde, V.3
-
59
-
-
0037438467
-
Dose escalation of imatinib mesylate can overcome resistance to standard-dose therapy in patients with chronic myelogenous leukemia
-
Kantarjian HM, Talpaz M, O'Brien S. Dose escalation of imatinib mesylate can overcome resistance to standard-dose therapy in patients with chronic myelogenous leukemia. Blood 2003;101:473-5.
-
(2003)
Blood
, vol.101
, pp. 473-475
-
-
Kantarjian, H.M.1
Talpaz, M.2
O'Brien, S.3
-
60
-
-
0035895106
-
Restoration of sensitivity to STI571-resistant chronic myeloid leukemia cells
-
Tipping AJ, Mahon FX, Lagarde V. Restoration of sensitivity to STI571-resistant chronic myeloid leukemia cells. Blood 2001;98:3864-7.
-
(2001)
Blood
, vol.98
, pp. 3864-3867
-
-
Tipping, A.J.1
Mahon, F.X.2
Lagarde, V.3
-
61
-
-
0742324616
-
Roots and management of imatinib resistance in BCR-ABL positive leukemias
-
Kreil S, Muller MC, Hanfstein B, et al. Roots and management of imatinib resistance in BCR-ABL positive leukemias. Blood 2002;100:368a.
-
(2002)
Blood
, vol.100
-
-
Kreil, S.1
Muller, M.C.2
Hanfstein, B.3
-
62
-
-
0742272228
-
Strategies for the treatment of imatinib-resistant chronic myeloid leukemia
-
Hui CH, Hughes TP. Strategies for the treatment of imatinib-resistant chronic myeloid leukemia. Clin Adv Hematol Oncol 2003;1:538-45.
-
(2003)
Clin Adv Hematol Oncol
, vol.1
, pp. 538-545
-
-
Hui, C.H.1
Hughes, T.P.2
-
63
-
-
0142121411
-
Imatinib mesylate (STI-571 Glivec(R), Gleevec) is an active agent for gastrointestinal stromal tumours but does not yield responses in other soft-tissue sarcomas that are unselected for a molecular target. Results from an EORTC Soft Tissue and Bone Sarcoma Group phase II study
-
Verweij J, van Oosterom A, Blay JY, et al. Imatinib mesylate (STI-571 Glivec(R), Gleevec) is an active agent for gastrointestinal stromal tumours but does not yield responses in other soft-tissue sarcomas that are unselected for a molecular target. Results from an EORTC Soft Tissue and Bone Sarcoma Group phase II study. Eur J Cancer 2003;39:2006-11.
-
(2003)
Eur J Cancer
, vol.39
, pp. 2006-2011
-
-
Verweij, J.1
Van Oosterom, A.2
Blay, J.Y.3
-
64
-
-
0344826038
-
Cloning of the t(1;5)(q23q33) in a myeloproliferative disorder associated with eosinophilia: Involvement of PDGFRB and response to imatinib
-
Wilkinson K, Velloso ER, Lopez LF, et al. Cloning of the t(1;5)(q23q33) in a myeloproliferative disorder associated with eosinophilia: involvement of PDGFRB and response to imatinib. Blood 2003;102:4187-90.
-
(2003)
Blood
, vol.102
, pp. 4187-4190
-
-
Wilkinson, K.1
Velloso, E.R.2
Lopez, L.F.3
-
65
-
-
0141816686
-
Imatinib mesylate elicits positive clinical response in atypical chronic myeloid leukemia involving the platelet derived-growth factor receptor beta
-
Garcia JL, Font de Mora J, Hernandez JM, et al. Imatinib mesylate elicits positive clinical response in atypical chronic myeloid leukemia involving the platelet derived-growth factor receptor beta. Blood 2003;102:2699-700.
-
(2003)
Blood
, vol.102
, pp. 2699-2700
-
-
Garcia, J.L.1
Font De Mora, J.2
Hernandez, J.M.3
-
66
-
-
0036682958
-
Activity of STI571 in chronic myelomonocytic leukemia with a platelet-derived growth factor β receptor fusion oncogene
-
Magnusson MK, Meade K, Nakamura R, et al. Activity of STI571 in chronic myelomonocytic leukemia with a platelet-derived growth factor β receptor fusion oncogene. Blood 2002;100:1088-91.
-
(2002)
Blood
, vol.100
, pp. 1088-1091
-
-
Magnusson, M.K.1
Meade, K.2
Nakamura, R.3
-
67
-
-
0041335547
-
Chronic myeloproliferative disorders with rearrangement of the platelet-derived growth factor alpha receptor: A new clinical target for STI571/Glivec
-
Trempat P, Villalva C, Laurent G. Chronic myeloproliferative disorders with rearrangement of the platelet-derived growth factor alpha receptor: a new clinical target for STI571/Glivec. Oncogene 2003;22:5702-6.
-
(2003)
Oncogene
, vol.22
, pp. 5702-5706
-
-
Trempat, P.1
Villalva, C.2
Laurent, G.3
-
68
-
-
0037343949
-
Polycythemia vera responds to imatinib mesylate
-
Jones CM, Dickinson TM. Polycythemia vera responds to imatinib mesylate. Am J Med Sci 2003;325:149-52.
-
(2003)
Am J Med Sci
, vol.325
, pp. 149-152
-
-
Jones, C.M.1
Dickinson, T.M.2
-
69
-
-
0141455965
-
Imatinib mesylate inhibits autonomous erythropoiesis in patients with polycythemia vera in vitro
-
Imatinib mesylate inhibits autonomous erythropoiesis in patients with polycythemia vera in vitro. Blood. 2003;102:2240-2.
-
(2003)
Blood
, vol.102
, pp. 2240-2242
-
-
-
70
-
-
0035823530
-
Case report: Rapid and complete control of idiopathic hypereosinophilia with imatinib mesylate
-
Schaller JL, Burkland GA. Case report: rapid and complete control of idiopathic hypereosinophilia with imatinib mesylate. Med Gen Med 2001;3:9.
-
(2001)
Med Gen Med
, vol.3
, pp. 9
-
-
Schaller, J.L.1
Burkland, G.A.2
-
71
-
-
0037018763
-
Treatment of hypereosinophilic syndrome with imatinib mesilate
-
Gleich GJ, Leiferman KM, Pardanani A, Tefferi A, Butterfield JH. Treatment of hypereosinophilic syndrome with imatinib mesilate. Lancet 2002;359:1577-8.
-
(2002)
Lancet
, vol.359
, pp. 1577-1578
-
-
Gleich, G.J.1
Leiferman, K.M.2
Pardanani, A.3
Tefferi, A.4
Butterfield, J.H.5
-
72
-
-
0036063077
-
Response of idiopathic hypereosinophilic syndrome to treatment with imatinib mesylate
-
Ault P, Cortes J, Koller C, Kaled ES, Kantarjian H. Response of idiopathic hypereosinophilic syndrome to treatment with imatinib mesylate. Leuk Res 2002;26:881-4.
-
(2002)
Leuk Res
, vol.26
, pp. 881-884
-
-
Ault, P.1
Cortes, J.2
Koller, C.3
Kaled, E.S.4
Kantarjian, H.5
-
73
-
-
0038386031
-
Imatinib therapy for hypereosinophilic syndrome and other eosinophilic disorders
-
Pardanani A, Reeder T, Porrata LF, et al. Imatinib therapy for hypereosinophilic syndrome and other eosinophilic disorders. Blood 2003;101:3391-7.
-
(2003)
Blood
, vol.101
, pp. 3391-3397
-
-
Pardanani, A.1
Reeder, T.2
Porrata, L.F.3
-
74
-
-
10744228476
-
Efficacy of imatinib mesylate in the treatment of idiopathic hypereosinophilic syndrome
-
Cortes J, Ault P, Koller C. Efficacy of imatinib mesylate in the treatment of idiopathic hypereosinophilic syndrome. Blood 2003;101:4714-6.
-
(2003)
Blood
, vol.101
, pp. 4714-4716
-
-
Cortes, J.1
Ault, P.2
Koller, C.3
-
75
-
-
0942276859
-
Molecular remission and reversal of myelofibrosis in response to imatinib mesylate treatment in patients with the myeloproliferative variant of hypereosinophilic syndrome
-
Klion AD, Robyn JA, Akin C, et al. Molecular remission and reversal of myelofibrosis in response to imatinib mesylate treatment in patients with the myeloproliferative variant of hypereosinophilic syndrome. Blood 2004;103:473-8.
-
(2004)
Blood
, vol.103
, pp. 473-478
-
-
Klion, A.D.1
Robyn, J.A.2
Akin, C.3
-
76
-
-
0037596569
-
Discovery of a fusion kinase in EOL-1 cells and idiopathic hypereosinophilic syndrome
-
Griffin JH, Leung J, Bruner RJ, Caligiuri MA, Briesewitz R. Discovery of a fusion kinase in EOL-1 cells and idiopathic hypereosinophilic syndrome. Proc Natl Acad Sci USA 2003;100:7830-5.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 7830-7835
-
-
Griffin, J.H.1
Leung, J.2
Bruner, R.J.3
Caligiuri, M.A.4
Briesewitz, R.5
-
77
-
-
0142119964
-
PKC412 overcomes resistance to imatinib in a murine model of FIP1L1-PDGFRalpha-induced myeloproliferative disease
-
Cools J, Stover EH, Boulton CL, et al. PKC412 overcomes resistance to imatinib in a murine model of FIP1L1-PDGFRalpha-induced myeloproliferative disease. Cancer Cell 2003;3:459-69.
-
(2003)
Cancer Cell
, vol.3
, pp. 459-469
-
-
Cools, J.1
Stover, E.H.2
Boulton, C.L.3
-
78
-
-
10744228486
-
CHIC2 deletion, a surrogate for FIP1L1-PDGFRA fusion, occurs in systemic mastocytosis associated with eosinophilia and predicts response to imatinib therapy
-
Pardanani A, Ketterling RP, Brockman SR. CHIC2 deletion, a surrogate for FIP1L1-PDGFRA fusion, occurs in systemic mastocytosis associated with eosinophilia and predicts response to imatinib therapy. Blood 2003;102:3093-6.
-
(2003)
Blood
, vol.102
, pp. 3093-3096
-
-
Pardanani, A.1
Ketterling, R.P.2
Brockman, S.R.3
|