Endogenous retroviral sequence is fused to FGFR1 kinase in the 8p12 stem-cell myeloproliferative disorder with t(8;19)(p12;q13.3)

Blood

Volumn 101, Issue 1, 2003, Pages 286-288

  Guasch, Géraldine ^a,b   Popovici, Cornel ^a,b   Mugneret, Francine ^a,b   Chaffanet, Max ^a,b   Pontarotti, Pierre ^a,b   Birnbaum, Daniel ^a,b   Pébusque, Marie Josephe ^a,b  

^a INSERM   (France)

^b HÔPITAL DU BOCAGE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR RECEPTOR 1;

ARTICLE; CHROMOSOME 19; CHROMOSOME 8; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; DIMERIZATION; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; LONG TERMINAL REPEAT; MYELOPROLIFERATIVE DISORDER; PRIORITY JOURNAL; PROTEIN DOMAIN; RETROVIRUS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS;

EID: 0037216062     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2002-02-0577     Document Type: Article

References (26)

1. Ponder BA. Cancer genetics. Nature. 2001;411:336-341.
2. Chaffanet M, Popovici C, Leroux D, et al. t(6;8), t(8;9) and t(8;13) translocations associated with stem cell myeloproliferative disorders have close or identical breakpoints in chromosome region 8p11-12. Oncogene. 1998;19:945-949.
3. MacDonald D, Aguiar RC, Mason PJ, Goldman JM, Cross NC. A new proliferative disorder associated with chromosomal translocations involving 8p12: A review. Leukemia. 1995;9:1628-1630.
4. Popovici C, Zhang B, Grégoire M-J, et al. The t(6;8)(q27;p11) translocation in a stem cell myeloproliferative disorder fuses a novel gene, FOP, to fibroblast growth factor 1. Blood. 1999;93:1381-1389.
5. Guasch G, Mack GJ, Popovici C, et al. FGFR1 is fused to the centrosome-associated protein CEP110 in the 8p12 stem cell myeloproliferative disorder with t(8;9)(p12;q33). Blood. 2000;95:1788-1796.
6. Popovici C, Adelaïde J, Oliendorff V, et al. Fibroblast growth factor receptor 1 is fused to FIM in stem-cell myeloproliferative disorder with t(8;13) (p12q12). Proc Natl Acad Sci U S A. 1998;95:5712-5717.
7. Reiter A, Sohal J, Kulkarni S, et al. Consistent fusion of ZNF198 to the fibroblast growth factor receptor-1 in thet(8;13)(p11;q12) myeloproliferative syndrome. Blood. 1998;92:1735-1742.
8. Smedley D, Hamoudi R, Clark J, et al. The t(8;13) (p11;q11-12) rearrangement associated with an atypical myeloproliferative disorder fuses the fibroblast growth factor receptor 1 gene to a novel gene RAMP. Hum Mol Genet. 1998;7:637-642.
9. Xiao S, Nalabolu SR, Aster JC, et al. FGFR1 is fused with a novel zinc-finger gene, ZNF198, in the t(8;13) leukaemia/lymphoma syndrome. Nat Genet. 1998;18:84-87.
10. Sohal J, Chase A, Mould S, et al. Identification of four new translocations involving FGFR1 in myeloid disorders. Genes Chromosomes Cancer. 2001;32:155-163.
11. Demiroglu A, Steer EJ, Heath C, et al. The t(8;22) in chronic myeloid leukemia fuses BCR to FGFR1: Transforming activity and specific inhibition of FGFR1 fusion proteins. Blood. 2001;98:3778-3783.
12. Fioretos T, Panagopoulos I, Lassen C, et al. Fusion of BCR to the fibroblast growth factor receptor-1 (FGFR1) genes as a result of t(8;22) (p11;q11) in a myeloproliferative disorder: The first fusion gene involving BCR but not ABL. Genes Chromosomes Cancer. 2001;32:302-310.
13. Mugneret F, Chaffanet M, Maynadié M, et al. The 8p12 myeloproliferative disorder, t(8;19)(p12;q13.3): A novel translocation involving the FGFR1 gene. Br J Haematol. 2000;111:647-649.
14. Chaffanet M, Imbert A, Adelaïde J, et al. A 3.1-Mb YAC contig within the Werner syndrome region, on the short arm of human chromosome 8. Cytogenet Cell Genet. 1996;72:63-68.
15. Tonjes RR, Czauderna F, Kurth R. Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K. J Virol. 1999;73:9187-9195.
16. Turner G, Barbulescu M, Su M, et al. Insertional polymorphisms of full-length endogenous retroviruses in humans. Curr Biol. 2001;11:1531-1535.
17. Urnovitz HB, Murphy WH. Human endogenous retroviruses: Nature, occurrence, and clinical implications in human disease. Clin Microbiol Rev. 1996;9:72-99.
18. Griffiths DJ. Endogenous retroviruses in the human genome sequence. Genome Biol. 2001;2:1017.
19. Medstrand P, Mager DL. Human-specific integrations of the HERV-K endogenous retrovirus family. J Virol. 1998;72:9782-9787.
20. Ono M. Molecular cloning and long terminal repeat sequences of human endogenous retrovirus genes related to types A and B retrovirus genes. J Virol, 1986;58:937-944.
21. Lower R. The pathogenic potential of endogenous retroviruses: Facts and fantasies. Trends Microbiol. 1999;7:350-356.
22. Montagna M, Santacatterina M, Torri A, et al. Identification of a 3 kb Alu-mediated BRCA1 gene rearrangement in two breast/ovarian cancer families. Oncogene. 1999;18:4160-4165.
23. Misra A, Chosdol K, Sarkar C, Mahapatra AK, Sinha S. Alteration of a sequence with homology to human endogenous retrovirus (HERV-K) in primary human glioma: Implications for viral repeat mediated rearrangement. Mutat Res. 2001;484:53-59.
24. Nagayama J, lino M, Tada Y, et al. Retrovirus insertion and transcriptional activation of the multidrug-resistance gene in leukemias treated by a chemotherapeutic agent in vivo. Blood. 2001;97:759-766.
25. Malvoisin E, Kieny MP, Wild F. Self-association of truncated forms of HIV-1 gp120, Virus Res. 1997;49:163-172.
26. Ollendorff V, Guasch G, Isnardon D, et al. Characterization of FIM-FGFR1, the fusion product of the myeloproliferative disorder-associated t(8;13) translocation, J Biol Chem. 1999;274:26922-26930.