메뉴 건너뛰기




Volumn 48, Issue 8, 2009, Pages 1181-1192

Dose prescription and optimisation based on tumour hypoxia

Author keywords

Oxygenation; PET imaging; Treatment optimization; Tumour oxygenation; Vasculature

Indexed keywords

ARTICLE; CANCER CONTROL; CELL HETEROGENEITY; HYPOXIA; IMAGING; OXYGENATION; PRIORITY JOURNAL; RADIATION DOSE; RADIATION DOSE DISTRIBUTION; RADIOSENSITIVITY; TUMOR;

EID: 70350787198     PISSN: 0284186X     EISSN: 1651226X     Source Type: Journal    
DOI: 10.3109/02841860903188643     Document Type: Article
Times cited : (63)

References (65)
  • 2
    • 0029955072 scopus 로고    scopus 로고
    • Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck
    • Nordsmark M, Overgaard M, Overgaard J. Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck. Radiother Oncol 1996;/41:/31-9.
    • (1996) Radiother Oncol , vol.41 , pp. 31-39
    • Nordsmark, M.1    Overgaard, M.2    Overgaard, J.3
  • 3
    • 0032708195 scopus 로고    scopus 로고
    • Oxygenation of head and neck cancer: Changes during radiotherapy and impact on treatment outcome
    • Brizel DM, Dodge RK, Clough RW, Dewhirst MW. Oxygenation of head and neck cancer: Changes during radiotherapy and impact on treatment outcome. Radiother Oncol 1999;/53:/113-7.
    • (1999) Radiother Oncol , vol.53 , pp. 113-117
    • Brizel, D.M.1    Dodge, R.K.2    Clough, R.W.3    Dewhirst, M.W.4
  • 4
    • 0034989311 scopus 로고    scopus 로고
    • Biological consequences of tumor hypoxia
    • Hö ckel M, Vaupel P. Biological consequences of tumor hypoxia. Semin Oncol 2001;/28:/36-41.
    • (2001) Semin Oncol , vol.28 , pp. 36-41
    • Höckel, M.1    Vaupel, P.2
  • 5
    • 0036467638 scopus 로고    scopus 로고
    • Tumor hypoxia has independent predictor impact only in patients with node-negative cervix cancer
    • Fyles A, Milosevic M, Hedley D, Pintilie M, Levin W, Manchul L, et al. Tumor hypoxia has independent predictor impact only in patients with node-negative cervix cancer. J Clin Oncol 2002;/20:/680-7.
    • (2002) J Clin Oncol , vol.20 , pp. 680-687
    • Fyles, A.1    Milosevic, M.2    Hedley, D.3    Pintilie, M.4    Levin, W.5    Manchul, L.6
  • 8
    • 0018123111 scopus 로고
    • Hyperbaric oxygen and radiotherapy: A Medical Research Council trial in carcinoma of the cervix
    • Watson ER, Halnan KE, Dische S, Saunders MI, Cade IS, McEwen JB, et al. Hyperbaric oxygen and radiotherapy: A Medical Research Council trial in carcinoma of the cervix. Br J Radiol 1978;/51:/879-87. (Pubitemid 9033490)
    • (1978) British Journal of Radiology , vol.51 , Issue.611 , pp. 879-887
    • Watson, E.R.1    Halnan, K.E.2    Dische, S.3
  • 9
    • 0031282041 scopus 로고    scopus 로고
    • Accelerated radiotherapy, carbogen and nicotinamide (ARCON) in locally advanced head and neck cancer: A feasibility study
    • Saunders MI, Hoskin PJ, Pigott K, Powell ME, Goodchild K, Dische S, et al. Accelerated radiotherapy, carbogen and nicotinamide (ARCON) in locally advanced head and neck cancer: A feasibility study. Radiother Oncol 1997;/45:/ 159-66.
    • (1997) Radiother Oncol , vol.45 , pp. 159-66
    • Saunders, M.I.1    Hoskin, P.J.2    Pigott, K.3    Powell, M.E.4    Goodchild, K.5    Dische, S.6
  • 11
    • 0021972468 scopus 로고
    • Chemical sensitizers for hypoxic cells: A decade of experience in clinical radiotherapy
    • Dische S. Chemical sensitizers for hypoxic cells: A decade of experience in clinical radiotherapy. Radiother Oncol 1985;/3:/ 97-115.
    • (1985) Radiother Oncol , vol.3 , pp. 97-115
    • Dische, S.1
  • 12
    • 0028632781 scopus 로고
    • Clinical evaluation of nitroimidazoles as modifiers of hypoxia in solid tumors
    • Overgaard J. Clinical evaluation of nitroimidazoles as modifiers of hypoxia in solid tumors. Oncol Res 1994;/6:/ 509-18.
    • (1994) Oncol Res , vol.6 , pp. 509-518
    • Overgaard, J.1
  • 13
    • 0030069889 scopus 로고    scopus 로고
    • Modification of Hypoxiainduced radioresistance in tumors by the use of oxygen and sensitizers
    • Overgaard J, Horsman MR. Modification of Hypoxiainduced radioresistance in tumors by the use of oxygen and sensitizers. Semin Radiat Oncol 1996;/6:/10-21.
    • (1996) Semin Radiat Oncol , vol.6 , pp. 10-21
    • Overgaard, J.1    Horsman, M.R.2
  • 15
    • 0742289163 scopus 로고    scopus 로고
    • Recent advances in light ion radiation therapy
    • Brahme A. Recent advances in light ion radiation therapy. Int J Radiat Oncol Biol Phys 2004;/58:/603-16.
    • (2004) Int J Radiat Oncol Biol Phys , vol.58 , pp. 603-616
    • Brahme, A.1
  • 16
    • 36448967770 scopus 로고    scopus 로고
    • The radiation response of heterogeneous tumors
    • Lind BK, Brahme A. The radiation response of heterogeneous tumors. Phys Med 2007;/23:/91-9.
    • (2007) Phys Med , vol.23 , pp. 91-99
    • Lind, B.K.1    Brahme, A.2
  • 17
    • 38849174333 scopus 로고    scopus 로고
    • Vascular oxygen content and the tissue oxygenation-a theoretical analysis
    • Daşu A, Toma-Daşu I. Vascular oxygen content and the tissue oxygenation-a theoretical analysis. Med Phys 2008;/ 35:/539-45.
    • (2008) Med Phys , vol.35 , pp. 539-545
    • Daşu, A.1    Toma-Daşu, I.2
  • 18
    • 46749143345 scopus 로고    scopus 로고
    • Molecular imaging of hypoxia
    • Krohn KA, Link JM, Mason RP. Molecular imaging of hypoxia. J Nucl Med 2008;/49(Suppl 2):/129S-148.
    • (2008) J Nucl Med , vol.49 , Issue.SUPPL. 2
    • Krohn, K.A.1    Link, J.M.2    Mason, R.P.3
  • 19
    • 0034213897 scopus 로고    scopus 로고
    • Towards multidimensional radiotherapy (MD-CRT): Biological imaging and biological conformality
    • Ling CC, Humm J, Larson S, Amols H, Fuks Z, Leibel S, et al. Towards multidimensional radiotherapy (MD-CRT): Biological imaging and biological conformality. Int J Radiat Oncol Biol Phys 2000;/47:/551-60.
    • (2000) Int J Radiat Oncol Biol Phys , vol.47 , pp. 551-560
    • Ling, C.C.1    Humm, J.2    Larson, S.3    Amols, H.4    Fuks, Z.5    Leibel, S.6
  • 20
    • 0141559026 scopus 로고    scopus 로고
    • On the inclusion of proliferation in tumour control probability calculations for inhomogeneously irradiated tumours
    • Tome WA, Fowler JF. On the inclusion of proliferation in tumour control probability calculations for inhomogeneously irradiated tumours. Phys Med Biol 2003;/48:/N261-8.
    • (2003) Phys Med Biol , vol.48
    • Tome, W.A.1    Fowler, J.F.2
  • 21
    • 0035869722 scopus 로고    scopus 로고
    • A novel approach to overcome hypoxic tumor resistance: Cu-ATSM-guided intensity-modulated radiation therapy
    • Chao KSC, Bosch WR, Mutic S, Lewis JS, Dehdashti F, Mintun MA, et al. A novel approach to overcome hypoxic tumor resistance: Cu-ATSM-guided intensity-modulated radiation therapy. Int J Radiat Oncol Biol Phys 2001;/49:/ 1171-82.
    • (2001) Int J Radiat Oncol Biol Phys , vol.49 , pp. 1171-1182
    • Chao, K.S.C.1    Bosch, W.R.2    Mutic, S.3    Lewis, J.S.4    Dehdashti, F.5    Mintun, M.A.6
  • 22
    • 34548511596 scopus 로고    scopus 로고
    • Hypoxia imaging with FAZA-PET and theoretical considerations with regard to dose painting for individualization of radiotherapy in patients with head and neck cancer
    • Grosu AL, Souvatzoglou M, Roper B, Dobritz M, Wiedenmann N, Jacob V, et al. Hypoxia imaging with FAZA-PET and theoretical considerations with regard to dose painting for individualization of radiotherapy in patients with head and neck cancer. Int J Radiat Oncol Biol Phys 2007;/69:/ 541-51.
    • (2007) Int J Radiat Oncol Biol Phys , vol.69 , pp. 541-551
    • Grosu, A.L.1    Souvatzoglou, M.2    Roper, B.3    Dobritz, M.4    Wiedenmann, N.5    Jacob, V.6
  • 23
    • 34848893337 scopus 로고    scopus 로고
    • Hypoxia positron emission tomography imaging with 18f-fluoromisonidazole
    • Lee ST, Scott AM. Hypoxia positron emission tomography imaging with 18f-fluoromisonidazole. Semin Nucl Med 2007;/37:/451-61.
    • (2007) Semin Nucl Med , vol.37 , pp. 451-461
    • Lee, S.T.1    Scott, A.M.2
  • 26
    • 3042634478 scopus 로고    scopus 로고
    • Feasibility of optimizing the dose distribution in lung tumors using fluorine-18-fluorodeoxyglucose positron emission tomography and single photon emission computed tomography guided dose prescriptions
    • Das SK, Miften MM, Zhou S, Bell M, Munley MT, Whiddon CS, et al. Feasibility of optimizing the dose distribution in lung tumors using fluorine-18-fluorodeoxyglucose positron emission tomography and single photon emission computed tomography guided dose prescriptions. Med Phys 2004;/31:/1452-61.
    • (2004) Med Phys , vol.31 , pp. 1452-1461
    • Das, S.K.1    Miften, M.M.2    Zhou, S.3    Bell, M.4    Munley, M.T.5    Whiddon, C.S.6
  • 28
    • 33947713604 scopus 로고    scopus 로고
    • Optimization of tumour control probability in hypoxic tumours by radiation dose redistribution: A modelling study
    • Søvik A, Malinen E, Bruland OS, Bentzen SM, Olsen DR. Optimization of tumour control probability in hypoxic tumours by radiation dose redistribution: A modelling study. Phys Med Biol 2007;/52:/499-513.
    • (2007) Phys Med Biol , vol.52 , pp. 499-513
    • Søvik, A.1    Malinen, E.2    Bruland, O.S.3    Bentzen, S.M.4    Olsen, D.R.5
  • 29
    • 48349130527 scopus 로고    scopus 로고
    • Intensity-modulated x-ray (IMXT) versus proton (IMPT) therapy for theragnostic hypoxia-based dose painting
    • Flynn RT, Bowen SR, Bentzen SM, Rockwell MT, Jeraj R. Intensity-modulated x-ray (IMXT) versus proton (IMPT) therapy for theragnostic hypoxia-based dose painting. Phys Med Biol 2008;/53:/4153-67.
    • Phys Med Biol 2008 , vol.53 , pp. 4153-4167
    • Flynn, R.T.1    Bowen, S.R.2    Bentzen, S.M.3    Rockwell, M.T.4    Jeraj, R.5
  • 30
    • 0029145952 scopus 로고
    • Evaluation of oxygenation status during fractionated radiotherapy in human nonsmall cell lung cancers using [F-18]fluoromisonidazole positron emission tomography
    • Koh WJ, Bergman KS, Rasey JS, Peterson LM, Evans ML, Graham MM, et al. Evaluation of oxygenation status during fractionated radiotherapy in human nonsmall cell lung cancers using [F-18]fluoromisonidazole positron emission tomography. Int J Radiat Oncol Biol Phys 1995;/33:/391-8.
    • (1995) Int J Radiat Oncol Biol Phys , vol.33 , pp. 391-398
    • Koh, W.J.1    Bergman, K.S.2    Rasey, J.S.3    Peterson, L.M.4    Evans, M.L.5    Graham, M.M.6
  • 31
    • 51049123629 scopus 로고    scopus 로고
    • Biological image-guided radiotherapy in rectal cancer: Is there a role for FMISO or FLT next to FDG?
    • Roels S, Slagmolen P, Nuyts J, Lee JA, Loeckx D, Maes F et al. Biological image-guided radiotherapy in rectal cancer: Is there a role for FMISO or FLT, next to FDG? Acta Oncol 2008;/47:/1237-48.
    • (2008) Acta Oncol , vol.47 , pp. 1237-1248
    • Roels, S.1    Slagmolen, P.2    Nuyts, J.3    Lee, J.A.4    Loeckx, D.5    Maes, F.6
  • 33
    • 0038364064 scopus 로고    scopus 로고
    • Biologically optimized 3-dimensional in vivo predictive assay-based radiation therapy using positron emission tomography-computerized tomography imaging
    • Brahme A. Biologically optimized 3-dimensional in vivo predictive assay-based radiation therapy using positron emission tomography-computerized tomography imaging. Acta Oncol 2003;/42:/123-36.
    • (2003) Acta Oncol , vol.42 , pp. 123-136
    • Brahme, A.1
  • 34
    • 0016518678 scopus 로고
    • Fractionation schedules and a quadratic dose-effect relationship
    • Douglas BG, Fowler JF. Fractionation schedules and a quadratic dose-effect relationship. Br J Radiol 1975;/48:/ 502-4.
    • (1975) Br J Radiol , vol.48 , pp. 502-504
    • Douglas, B.G.1    Fowler, J.F.2
  • 35
    • 0020215010 scopus 로고
    • Dose fractionation, dose rate and iso-effect relationships for normal tissue responses
    • Barendsen GW. Dose fractionation, dose rate and iso-effect relationships for normal tissue responses. Int J Radiat Oncol Biol Phys 1982;/8:/1981-97.
    • (1982) Int J Radiat Oncol Biol Phys , vol.8 , pp. 1981-1997
    • Barendsen, G.W.1
  • 36
    • 0024358259 scopus 로고
    • The linear-quadratic formula and progress in fractionated radiotherapy
    • Fowler JF. The linear-quadratic formula and progress in fractionated radiotherapy. Br J Radiol 1989;/62:/679-94.
    • (1989) Br J Radiol , vol.62 , pp. 679-694
    • Fowler, J.F.1
  • 37
    • 0001581235 scopus 로고
    • Role of oxygen in modifying the radiosensitivity of E. Coli B
    • Alper T, Howard-Flanders P. Role of oxygen in modifying the radiosensitivity of E. Coli B. Nature 1956;/178:/978-9.
    • (1956) Nature , vol.178 , pp. 978-979
    • Alper, T.1    Howard-Flanders, P.2
  • 38
    • 0003696140 scopus 로고
    • Cambridge: Cambridge University Press
    • Alper T. Cellular radiobiology. Cambridge: Cambridge University Press; 1979.
    • (1979) Cellular Radiobiology
    • Alper, T.1
  • 40
    • 0028864232 scopus 로고
    • Volume and heterogeneity dependence of the dose-response relationship for head and neck tumours
    • A°gren Cronqvist AK, Kallman P, Turesson I, Brahme A. Volume and heterogeneity dependence of the dose-response relationship for head and neck tumours. Acta Oncol 1995;/ 34:/851-60.
    • (1995) Acta Oncol , vol.34 , pp. 851-860
    • Agren Cronqvist, A.K.1    Kallman, P.2    Turesson, I.3    Brahme, A.4
  • 41
    • 0023544520 scopus 로고
    • Optimal dose distribution for eradication of heterogeneous tumours
    • Brahme A, .A° gren AK. Optimal dose distribution for eradication of heterogeneous tumours. Acta Oncol 1987;/26:/ 377-85.
    • (1987) Acta Oncol , vol.26 , pp. 377-385
    • Brahme, A.1    Agren, A.K.2
  • 42
    • 0036716726 scopus 로고    scopus 로고
    • Vascular architecture, hypoxia, and proliferation in first-generation xenografts of human head-and-neck squamous cell carcinomas
    • Ljungkvist ASE, Bussink J, Rijken PFJW, Kaanders JHAM, van der Kogel AJ, Denekamp J. Vascular architecture, hypoxia, and proliferation in first-generation xenografts of human head-and-neck squamous cell carcinomas. Int J Radiat Oncol Biol Phys 2002;/54:/215-28.
    • (2002) Int J Radiat Oncol Biol Phys , vol.54 , pp. 215-228
    • Ljungkvist, A.S.E.1    Bussink, J.2    Pfjw, R.3    Jham, K.4    Van Der Kogel, A.J.5    Denekamp, J.6
  • 43
    • 0141514459 scopus 로고    scopus 로고
    • Theoretical simulation of tumour oxygenation and results from acute and chronic hypoxia
    • Daşu A, Toma-Daşu I, Karlsson M. Theoretical simulation of tumour oxygenation and results from acute and chronic hypoxia. Phys Med Biol 2003;/48:/2829-42.
    • (2003) Phys Med Biol , vol.48 , pp. 2829-2842
    • Daşu, A.1    Toma-Daşu, I.2    Karlsson, M.3
  • 44
    • 33846862934 scopus 로고    scopus 로고
    • A model to simulate tumour oxygenation and dynamic [18F]-Fmiso PET data
    • Kelly CJ, Brady M. A model to simulate tumour oxygenation and dynamic [18F]-Fmiso PET data. Phys Med Biol 2006;/ 51:/5859-73.
    • (2006) Phys Med Biol , vol.51 , pp. 5859-5873
    • Kelly, C.J.1    Brady, M.2
  • 45
    • 0002387112 scopus 로고    scopus 로고
    • Dosimetric precision requirements and quantities for characterizing the response of tumors and normal tissues
    • Brahme A. Dosimetric precision requirements and quantities for characterizing the response of tumors and normal tissues. IAEA-TECDOC 1996;/896:/49-65.
    • (1996) IAEA-TECDOC , vol.896 , pp. 49-65
    • Brahme, A.1
  • 46
    • 0010990601 scopus 로고
    • Dosimetric precision requirements in radiation therapy
    • Brahme A. Dosimetric precision requirements in radiation therapy. Acta Radiol Oncol 1984;/23:/379-91.
    • (1984) Acta Radiol Oncol , vol.23 , pp. 379-391
    • Brahme, A.1
  • 47
    • 0024408986 scopus 로고
    • Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: A review
    • Vaupel P, Kallinowski F, Okunieff P. Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: A review. Cancer Res 1989;/49:/6449-65.
    • (1989) Cancer Res , vol.49 , pp. 6449-65
    • Vaupel, P.1    Kallinowski, F.2    Okunieff, P.3
  • 48
    • 84934440562 scopus 로고    scopus 로고
    • Theoretical simulation of tumour oxygenation- practical applications
    • Daşu A, Toma-Daşu I. Theoretical simulation of tumour oxygenation- practical applications. Adv Exp Med Biol 2006;/578:/357-62.
    • (2006) Adv Exp Med Biol , vol.578 , pp. 357-362
    • Daşu, A.1    Toma-Daşu, I.2
  • 49
    • 61849177483 scopus 로고    scopus 로고
    • Quantifying tumour hypoxia by PET imaging- a theoretical analysis
    • Toma-Daşu I, Daşu A, Brahme A. Quantifying tumour hypoxia by PET imaging- a theoretical analysis. Adv Exp Med Biol 2009;/645:/267-72.
    • (2009) Adv Exp Med Biol , vol.645 , pp. 267-272
    • Toma-Daşu, I.1    Daşu, A.2    Brahme, A.3
  • 50
    • 84960987950 scopus 로고
    • The concentration of oxygen dissolved in tissues at the time of irradiation as a factor in radiotherapy
    • Gray LH, Conger AD, Ebert M, Hornsey S, Scott OCA. The concentration of oxygen dissolved in tissues at the time of irradiation as a factor in radiotherapy. Br J Radiol 1953;/ 26:/638-48.
    • (1953) Br J Radiol , vol.26 , pp. 638-648
    • Gray, L.H.1    Conger, A.D.2    Ebert, M.3    Hornsey, S.4    Scott, O.C.A.5
  • 51
    • 34748860952 scopus 로고    scopus 로고
    • Hypoxic radiosensitization: Adored and ignored
    • Overgaard J. Hypoxic radiosensitization: Adored and ignored. J Clin Oncol 2007;/25:/4066-74.
    • (2007) J Clin Oncol , vol.25 , pp. 4066-4074
    • Overgaard, J.1
  • 52
    • 0023107539 scopus 로고
    • Intermittent blood flow in a murine tumor: Radiobiological effects
    • Chaplin DJ, Olive PL, Durand RE. Intermittent blood flow in a murine tumor: Radiobiological effects. Cancer Res 1987;/47:/597-601.
    • (1987) Cancer Res , vol.47 , pp. 597-5601
    • Chaplin, D.J.1    Olive, P.L.2    Durand, R.E.3
  • 53
    • 0032944785 scopus 로고    scopus 로고
    • Vascular architecture and microenvironmental parameters in human squamous cell carcinoma xenografts: Effects of carbogen and nicotinamide
    • Bussink J, Kaanders JHAM, Rijken PFJW, Peters JPW, Hodgkiss RJ, Marres HAM, et al. Vascular architecture and microenvironmental parameters in human squamous cell carcinoma xenografts: Effects of carbogen and nicotinamide. Radiother Oncol 1999;/50:/173-83.
    • (1999) Radiother Oncol , vol.50 , pp. 173-183
    • Bussink, J.1    Jham, K.2    Pfjw, R.3    Peters, J.P.W.4    Hodgkiss, R.J.5    Marres, H.A.M.6
  • 54
    • 0034265986 scopus 로고    scopus 로고
    • Spatial relationship between hypoxia and the (perfused) vascular network in a human glioma xenograft: A quantitative multi-parameter analysis
    • Rijken PFJW, Bernsen HJJA, Peters JPW, Hodgkiss RJ, Raleigh JA, van der Kogel AJ. Spatial relationship between hypoxia and the (perfused) vascular network in a human glioma xenograft: A quantitative multi-parameter analysis. Int J Radiat Oncol Biol Phys 2000;/48:/571-82.
    • (2000) Int J Radiat Oncol Biol Phys , vol.48 , pp. 571-582
    • Pfjw, R.1    Hjja, B.2    Peters, J.P.W.3    Hodgkiss, R.J.4    Raleigh, J.A.5    Van Der Kogel, A.J.6
  • 55
    • 34250334707 scopus 로고    scopus 로고
    • Hypoxia-imaging with (18)FMisonidazole and PET: Changes of kinetics during radiotherapy of head-and-neck cancer
    • Eschmann SM, Paulsen F, Bedeshem C, Machulla HJ, Hehr T, Bamberg M, et al. Hypoxia-imaging with (18)FMisonidazole and PET: Changes of kinetics during radiotherapy of head-and-neck cancer. Radiother Oncol 2007;/83:/ 406-10.
    • (2007) Radiother Oncol , vol.83 , pp. 406-410
    • Eschmann, S.M.1    Paulsen, F.2    Bedeshem, C.3    MacHulla, H.J.4    Hehr, T.5    Bamberg, M.6
  • 56
    • 0021685559 scopus 로고
    • The detection and measurement of hypoxic cells in solid tumors
    • Chapman JD. The detection and measurement of hypoxic cells in solid tumors. Cancer 1984;/54:/2441-9.
    • (1984) Cancer , vol.54 , pp. 2441-2449
    • Chapman, J.D.1
  • 57
    • 70350761271 scopus 로고    scopus 로고
    • Therapy optimization based on non-linear uptake of PET tracers versus "linear dose painting"
    • (in press)
    • Toma-Daşu I, Uhrdin J, Daşu A, Brahme A. Therapy optimization based on non-linear uptake of PET tracers versus "linear dose painting". IFMBE Proceedings 2009 (in press).
    • (2009) IFMBE Proceedings
    • Toma-Daşu, I.1    Uhrdin, J.2    Daşu, A.3    Brahme, A.4
  • 59
    • 0032587188 scopus 로고    scopus 로고
    • Characterization of [18F]fluoroetanidazole, a new radiopharmaceutical for detecting tumor hypoxia
    • Rasey JS, Hofstrand PD, Chin LK, Tewson TJ. Characterization of [18F]fluoroetanidazole, a new radiopharmaceutical for detecting tumor hypoxia. J Nucl Med 1999;/40:/ 1072-9.
    • (1999) J Nucl Med , vol.40 , pp. 1072-1079
    • Rasey, J.S.1    Hofstrand, P.D.2    Chin, L.K.3    Tewson, T.J.4
  • 61
    • 5444228799 scopus 로고    scopus 로고
    • PO (2) Polarography versus positron emission tomography ([(18)F] fluoromisonidazole, [ (18)F] -2-fluoro-2?-deoxyglucose). An appraisal of radiotherapeutically relevant hypoxia
    • Gagel B, Reinartz P, Dimartino E, Zimny M, Pinkawa M, Maneschi P, et al. pO(2) Polarography versus positron emission tomography ([(18)F] fluoromisonidazole, [(18)F] -2-fluoro-2?-deoxyglucose). An appraisal of radiotherapeutically relevant hypoxia. Strahlenther Onkol 2004;/180:/ 616-22.
    • (2004) Strahlenther Onkol , vol.180 , pp. 616-622
    • Gagel, B.1    Reinartz, P.2    Dimartino, E.3    Zimny, M.4    Pinkawa, M.5    Maneschi, P.6
  • 62
    • 20144387807 scopus 로고    scopus 로고
    • Assessment of regional tumor hypoxia using 18F-fluoromisonidazole and 64Cu(II)-diacetyl-bis (N4-methylthiosemicarbazone) positron emission tomography: Comparative study featuring microPET imaging, Po2 probe measurement, autoradiography, and fluorescent microscopy in the R3327-AT and FaDu rat tumor models
    • O'Donoghue JA, Zanzonico P, Pugachev A, Wen B, Smith- Jones P, Cai S, et al. Assessment of regional tumor hypoxia using 18F-fluoromisonidazole and 64Cu(II)-diacetyl-bis (N4-methylthiosemicarbazone) positron emission tomography: Comparative study featuring microPET imaging, Po2 probe measurement, autoradiography, and fluorescent microscopy in the R3327-AT and FaDu rat tumor models. Int J Radiat Oncol Biol Phys 2005;/61:/1493-502.
    • (2005) Int J Radiat Oncol Biol Phys , vol.61 , pp. 1493-1502
    • O'Donoghue, J.A.1    Zanzonico, P.2    Pugachev, A.3    Wen, B.4    Smith- Jones, P.5    Cai, S.6
  • 63
    • 0036661191 scopus 로고    scopus 로고
    • Theoretical simulation of oxygen tension measurement in the tissue using a microelectrode: II. Simulated measurements in tissues
    • Toma-Daşu I, Daşu A, Waites A, Denekamp J, Fowler JF. Theoretical simulation of oxygen tension measurement in the tissue using a microelectrode: II. Simulated measurements in tissues. Radiother Oncol 2002;/64:/109-18.
    • (2002) Radiother Oncol , vol.64 , pp. 109-118
    • Toma-Daşu, I.1    Daşu, A.2    Waites, A.3    Denekamp, J.4    Fowler, J.F.5
  • 64
    • 5744227339 scopus 로고    scopus 로고
    • The relationship between temporal variation of hypoxia, polarographic measurements and predictions of tumour response to radiation
    • Toma-Daşu I, Daşu A, Karlsson M. The relationship between temporal variation of hypoxia, polarographic measurements and predictions of tumour response to radiation. Phys Med Biol 2004;/49:/4463-75.
    • (2004) Phys Med Biol , vol.49 , pp. 4463-4475
    • Toma-Daşu, I.1    Daşu, A.2    Karlsson, M.3
  • 65
    • 51049084219 scopus 로고    scopus 로고
    • Treatment planning optimisation based on imaging tumour proliferation and cell density
    • Daşu A. Treatment planning optimisation based on imaging tumour proliferation and cell density. Acta Oncol 2008;/47:/ 1221-8.
    • (2008) Acta Oncol , vol.47 , pp. 1221-1228
    • Daşu, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.