Quantifying tumour hypoxia by PET imaging - A theoretical analysis

Advances in Experimental Medicine and Biology

Volumn 645, Issue , 2009, Pages 267-272

  Toma Daşu, Iuliana ^a   Daşu, Alexandru ^b   Brahme, Anders ^a  

^a STOCKHOLM UNIVERSITY   (Sweden)

^b UMEÅ UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

TRACER; BIOLOGICAL MARKER; OXYGEN;

ALGORITHM; CANCER CONTROL; CONFERENCE PAPER; CONTROLLED STUDY; DOSIMETRY; HYPOXIA; IMAGE QUALITY; LIMIT OF QUANTITATION; POSITRON EMISSION TOMOGRAPHY; PREDICTION; PRIORITY JOURNAL; PROCESS OPTIMIZATION; RADIATION DOSE DISTRIBUTION; SIMULATION; TISSUE OXYGENATION; TUMOR CELL; TUMOR LOCALIZATION; TUMOR MODEL; TUMOR SCINTISCANNING; ANOXIA; ARTICLE; BIOLOGICAL MODEL; COMPUTER SIMULATION; METABOLISM; METHODOLOGY; NEOPLASM;

ANOXIA; BIOLOGICAL MARKERS; COMPUTER SIMULATION; MODELS, BIOLOGICAL; NEOPLASMS; OXYGEN; POSITRON-EMISSION TOMOGRAPHY;

EID: 61849177483     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-0-387-85998-9_40     Document Type: Conference Paper

References (20)

1. M. Nordsmark, M. Overgaard, and J. Overgaard, Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck, Radiother. Oncol. 41, 31-39(1996). (Pubitemid 26396294)
2. M. Höckel and P. Vaupel, Biological consequences of tumor hypoxia, Semin. Oncol. 28, 36-41(2001). (Pubitemid 32522236)
3. A. Brahme, Biologically optimized 3-dimensional in vivo predictive assay-based radiation therapy using positron emission tomography-computerized tomography imaging, Acta Oncol. 42, 123-136(2003). (Pubitemid 36570777)
4. A. Brahme, Fractionated and biologically optimized IMRT using in vivo predictive assay based radiation therapy (BIOART), Proceedings of the Fifth International Symposium on Target Volume Definition in Radiation Oncology (Limburg, 2005).
5. J. S. Rasey, W. J. Koh, M. L. Evans, L. M. Peterson, T. K. Lewellen, M. M. Graham, and K. A. Krohn, Quantifying regional hypoxia in human tumors with positron emission tomography of [18F]fluoromisonidazole: a pretherapy study of 37 patients, Int. J. Radiat. Oncol. Biol. Phys. 36, 417-428(1996).
6. J. S. Lewis, D. W. McCarthy, T. J. McCarthy, Y. Fujibayashi, and M. J. Welch, Evaluation of 64Cu-ATSM in vitro and in vivo in a hypoxic tumor model, J. Nucl. Med. 40, 177-183(1999). (Pubitemid 29044189)
7. F. Dehdashti, P. W. Grigsby, M. A. Mintun, J. S. Lewis, B. A. Siegel, and M. J. Welch, Assessing tumor hypoxia in cervical cancer by positron emission tomography with 60Cu-ATSM: relationship to therapeutic response-a preliminary report, Int. J. Radiat. Oncol. Biol. Phys. 55, 1233-1238(2003). (Pubitemid 36338289)
8. B. K. Lind and A. Brahme, The radiation response of heterogeneous tumors, Physica Medica (in press).
9. I. Toma-Daşu, Theoretical modelling of tumour oxygenation and influences on treatment outcome, PhD Thesis, Umeå University (2004).
10. J. S. Rasey, P. D. Hofstrand, L. K. Chin, and T. J. Tewson, Characterization of [18F]fluoroetanidazole, a new radiopharmaceutical for detecting tumor hypoxia, J. Nucl. Med. 40, 1072-1079(1999). (Pubitemid 29269230)
11. A. Daşu, I. Toma-Daşu, and M. Karlsson, Theoretical simulation of tumour oxygenation and results from acute and chronic hypoxia, Phys. Med. Biol. 48, 2829-2842(2003). (Pubitemid 37121463)
12. A. Daşu and I. Toma-Daşu, Theoretical simulation of tumour oxygenation-practical applications, Adv. Exp. Med. Biol. 578, 357-362(2006).
13. B. G. Douglas and J. F. Fowler, Fractionation schedules and a quadratic dose-effect relationship, Br. J. Radiol. 48, 502-504(1975).
14. G. W. Barendsen, Dose fractionation, dose rate and iso-effect relationships for normal tissue responses, Int. J. Radiat. Oncol. Biol. Phys. 8, 1981-1997(1982). (Pubitemid 13167385)
15. J. F. Fowler, The linear-quadratic formula and progress in fractionated radiotherapy, Br. J. Radiol. 62, 679-694(1989). (Pubitemid 19194494)
16. H. D. Thames, S. M. Bentzen, I. Turesson, M. Overgaard, and W. Van den Bogaert, Time-dose factors in radiotherapy: a review of the human data, Radiother. Oncol. 19, 219-235(1990). (Pubitemid 20369216)
17. T. Alper and P. Howard-Flanders, Role of oxygen in modifying the radiosensitivity of E. Coli B., Nature 178, 978-979(1956).
18. A. Yaromina, D. Zips, H. D. Thames, W. Eicheler, M. Krause, A. Rosner, M. Haase, C. Petersen, J. A. Raleigh, V. Quennet, S. Walenta, W. Mueller-Klieser, and M. Baumann, Pimonidazole labelling and response to fractionated irradiation of five human squamous cell carcinoma (hSCC) lines in nude mice: the need for a multivariate approach in biomarker studies, Radiother. Oncol. 81, 122-129(2006). (Pubitemid 44780780)
19. A. Brahme and A. K. Agren, Optimal dose distribution for eradication of heterogeneous tumours, Acta Oncol. 26, 377-385(1987). (Pubitemid 18044580)
20. G. Kåver, B. K. Lind, J. Löf, A. Liander, and A. Brahme, Stochastic optimization of intensity modulated radiotherapy to account for uncertainties in patient sensitivity, Phys. Med. Biol. 44, 2955-2969(1999).