-
1
-
-
0242384751
-
Natural history and functional divergence of protein tyrosine kinases
-
DOI 10.1016/S0378-1119(03)00696-6
-
Gu, J. and Gu, X. (2003) Natural history and functional divergence of protein tyrosine kinases. Gene 317, 49-57. (Pubitemid 37356917)
-
(2003)
Gene
, vol.317
, Issue.1-2
, pp. 49-57
-
-
Gu, J.1
Gu, X.2
-
2
-
-
0036806311
-
Evolution of protein kinase signaling from yeast to man
-
Manning, G., Plowman, G. D., Hunter, T., and Sudarsanam, S. (2002) Evolution of protein kinase signaling from yeast to man. Trends Biochem. Sci. 27, 514-520.
-
(2002)
Trends Biochem. Sci.
, vol.27
, pp. 514-520
-
-
Manning, G.1
Plowman, G.D.2
Hunter, T.3
Sudarsanam, S.4
-
3
-
-
0037032835
-
The protein kinase complement of the human genome
-
DOI 10.1126/science.1075762
-
Manning, G., Whyte, D. B., Martinez, R., Hunter, T., and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science 298, 1912-1934. (Pubitemid 35425239)
-
(2002)
Science
, vol.298
, Issue.5600
, pp. 1912-1934
-
-
Manning, G.1
Whyte, D.B.2
Martinez, R.3
Hunter, T.4
Sudarsanam, S.5
-
4
-
-
0037158810
-
Human members of the eukaryotic protein kinase family
-
Kostich, M., English, J., Madison, V., Gheyas, F., Wang, L., Qiu, P., Greene, J., and Laz, T. M. (2002) Human members of the eukaryotic protein kinase family. Genome Biol. 3, 43.1-43.12.
-
(2002)
Genome Biol.
, vol.3
-
-
Kostich, M.1
English, J.2
Madison, V.3
Gheyas, F.4
Wang, L.5
Qiu, P.6
Greene, J.7
Laz, T.M.8
-
5
-
-
0033786922
-
Protein tyrosine kinase structure and function
-
Hubbard, S. R. and Till, J. H. (2000) Protein tyrosine kinase structure and function. Annu. Rev. Biochem. 69, 373-398.
-
(2000)
Annu. Rev. Biochem.
, vol.69
, pp. 373-398
-
-
Hubbard, S.R.1
Till, J.H.2
-
6
-
-
0034693799
-
The protein tyrosine kinase family of the human genome
-
Robinson, D. R., Wu, Y. M., and Lin, S. F. (2000) The protein tyrosine kinase family of the human genome. Oncogene 19, 5548-5557.
-
(2000)
Oncogene
, vol.19
, pp. 5548-5557
-
-
Robinson, D.R.1
Wu, Y.M.2
Lin, S.F.3
-
7
-
-
33646875489
-
Origin and molecular evolution of receptor tyrosine kinases with immunoglobulin-like domains
-
Grassot, J., Gouy, M., Perriere, G., and Mouchiroud, G. (2006) Origin and molecular evolution of receptor tyrosine kinases with immunoglobulin-like domains. Mol. Biol. Evol. 23, 1232-1241.
-
(2006)
Mol. Biol. Evol.
, vol.23
, pp. 1232-1241
-
-
Grassot, J.1
Gouy, M.2
Perriere, G.3
Mouchiroud, G.4
-
8
-
-
0021111648
-
Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid
-
Senger, D. R., Galli, S. J., Dvorak, A. M., Perruzzi, C. A., Harvey, V. S., and Dvorak, H. F. (1983) Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science 219, 983-985.
-
(1983)
Science
, vol.219
, pp. 983-985
-
-
Senger, D.R.1
Galli, S.J.2
Dvorak, A.M.3
Perruzzi, C.A.4
Harvey, V.S.5
Dvorak, H.F.6
-
9
-
-
66349093990
-
History of discovery: Vascular endothelial growth factor
-
PMID: 19164810
-
Ferrara, N. (2009) History of discovery: vascular endothelial growth factor. Arterioscler. Thromb. Vasc. Biol. 29, 789-791, PMID: 19164810.
-
(2009)
Arterioscler. Thromb. Vasc. Biol.
, vol.29
, pp. 789-791
-
-
Ferrara, N.1
-
10
-
-
33344463349
-
Discovery of vascular permeability factor (VPF)
-
Dvorak, H. F. (2006) Discovery of vascular permeability factor (VPF). Exp. Cell Res. 312, 522-526.
-
(2006)
Exp. Cell Res.
, vol.312
, pp. 522-526
-
-
Dvorak, H.F.1
-
11
-
-
0024384470
-
Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells
-
Ferrara, N. and Henzel, W. J. (1989) Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells. Biochem. Biophys. Res. Commun. 161, 851-858.
-
(1989)
Biochem. Biophys. Res. Commun.
, vol.161
, pp. 851-858
-
-
Ferrara, N.1
Henzel, W.J.2
-
12
-
-
0024816246
-
Isolation and characterization of a newly identified endothelial cell mitogen produced by AtT-20 cells
-
Plouet, J., Schilling, J., and Gospodarowicz, D. (1989) Isolation and characterization of a newly identified endothelial cell mitogen produced by AtT-20 cells. EMBO J. 8, 3801-3806. (Pubitemid 20016061)
-
(1989)
EMBO Journal
, vol.8
, Issue.12
, pp. 3801-3806
-
-
Plouet, J.1
Schilling, J.2
Gospodarowicz, D.3
-
13
-
-
0024801035
-
Vascular permeability factor, an endothelial cell mitogen related to PDGF
-
Keck, P. J., Hauser, S. D., Krivi, G., Sanzo, K., Warren, T., Feder, J., and Connolly, D. T. (1989) Vascular permeability factor, an endothelial cell mitogen related to PDGF. Science 246, 1309-1312. (Pubitemid 20066717)
-
(1989)
Science
, vol.246
, Issue.4935
, pp. 1309-1312
-
-
Keck, P.J.1
Hauser, S.D.2
Krivi, G.3
Sanzo, K.4
Warren, T.5
Feder, J.6
Connolly, D.T.7
-
14
-
-
0024818355
-
Vascular endothelial growth factor is a secreted angiogenic mitogen
-
Leung, D. W., Cachianes, G., Kuang, W. J., Goeddel, D. V., and Ferrara, N. (1989) Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 246, 1306-1309. (Pubitemid 20066716)
-
(1989)
Science
, vol.246
, Issue.4935
, pp. 1306-1309
-
-
Leung, D.W.1
Cachianes, G.2
Kuang, W.-J.3
Goeddel, D.V.4
Ferrara, N.5
-
15
-
-
0035062394
-
The splice variants of vascular endothelial growth factor (VEGF) and their receptors
-
Robinson, C. J. and Stringer, S. E. (2001) The splice variants of vascular endothelial growth factor (VEGF) and their receptors. J. Cell Sci. 114, 853-865. (Pubitemid 32273121)
-
(2001)
Journal of Cell Science
, vol.114
, Issue.5
, pp. 853-865
-
-
Robinson, C.J.1
Stringer, S.E.2
-
16
-
-
22344437713
-
Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors
-
DOI 10.1083/jcb.200409115
-
Lee, S., Jilani, S. M., Nikolova, G. V., Carpizo, D., and Iruela-Arispe, M. L. (2005) Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors. J. Cell Biol. 169, 681-691. (Pubitemid 41002860)
-
(2005)
Journal of Cell Biology
, vol.169
, Issue.4
, pp. 681-691
-
-
Lee, S.1
Jilan, S.M.2
Nikolova, G.V.3
Carpizo, D.4
Luisa Iruela-Arispe, M.5
-
17
-
-
54549123309
-
VEGF-A splicing: The key to anti-angiogenic therapeutics?
-
Harper, S. J. and Bates, D. O. (2008) VEGF-A splicing: the key to anti-angiogenic therapeutics? Nat. Rev. Cancer 8, 880-887.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 880-887
-
-
Harper, S.J.1
Bates, D.O.2
-
18
-
-
0141996422
-
Vascular endothelial growth factor receptor-2: Its unique signaling and specific ligand, VEGF-E
-
Shibuya, M. (2003) Vascular endothelial growth factor receptor-2: its unique signaling and specific ligand, VEGF-E. Cancer Sci. 94, 751-756.
-
(2003)
Cancer Sci.
, vol.94
, pp. 751-756
-
-
Shibuya, M.1
-
19
-
-
65649109754
-
Snake venom vascular endothelial growth factors (VEGF-Fs) exclusively vary their structures and functions among species
-
Yamazaki, Y., Matsunaga, Y., Tokunaga, Y., Obayashi, S., Saito, M., and Morita, T. (2009) Snake venom vascular endothelial growth factors (VEGF-Fs) exclusively vary their structures and functions among species. J. Biol. Chem. 284, 9885-9891.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 9885-9891
-
-
Yamazaki, Y.1
Matsunaga, Y.2
Tokunaga, Y.3
Obayashi, S.4
Saito, M.5
Morita, T.6
-
20
-
-
33645056182
-
The role of VEGF receptors in angiogenesis; complex partnerships
-
Cébe-Suarez, S., Zehnder-Fjällman, A. H., and Ballmer-Hofer, K. (2006) The role of VEGF receptors in angiogenesis; complex partnerships. Cell. Mol. Life Sci. 63, 601-615.
-
(2006)
Cell. Mol. Life Sci.
, vol.63
, pp. 601-615
-
-
Cébe-Suarez, S.1
Zehnder-Fjällman, A.H.2
Ballmer-Hofer, K.3
-
21
-
-
33344474964
-
Signal transduction by VEGF receptors in regulation of angiogenesis and lymphangiogenesis
-
Shibuya, M. and Claesson-Welsh, L. (2005) Signal transduction by VEGF receptors in regulation of angiogenesis and lymphangiogenesis. Exp. Cell Res. 312, 549-560.
-
(2005)
Exp. Cell Res.
, vol.312
, pp. 549-560
-
-
Shibuya, M.1
Claesson-Welsh, L.2
-
22
-
-
49949152181
-
Vascular permeability, vascular hyperpermeability and angiogenesis
-
Nagy, J. A., Benjamin, L., Zeng, H., Dvorak, A. M., and Dvorak, H. F. (2008) Vascular permeability, vascular hyperpermeability and angiogenesis. Angiogenesis 11, 109-119.
-
(2008)
Angiogenesis
, vol.11
, pp. 109-119
-
-
Nagy, J.A.1
Benjamin, L.2
Zeng, H.3
Dvorak, A.M.4
Dvorak, H.F.5
-
23
-
-
0343920277
-
Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
-
Carmeliet, P., Ferreira, V., Breier, G., Pollefeyt, S., Kieckens, L., Gertsenstein, M., Fahrig, M., Vandenhoeck, A., Harpal, K., Eberhardt, C., Declercq, C., Pawling, J., Moons, L., Collen, D., Risau, W., and Nagy, A. (1996) Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 380, 435-439.
-
(1996)
Nature
, vol.380
, pp. 435-439
-
-
Carmeliet, P.1
Ferreira, V.2
Breier, G.3
Pollefeyt, S.4
Kieckens, L.5
Gertsenstein, M.6
Fahrig, M.7
Vandenhoeck, A.8
Harpal, K.9
Eberhardt, C.10
Declercq, C.11
Pawling, J.12
Moons, L.13
Collen, D.14
Risau, W.15
Nagy, A.16
-
24
-
-
0030004485
-
Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene
-
Ferrara, N., Carver Moore, K., Chen, H., Dowd, M., Lu, L., O Shea, K. S., Powell, B. L., Hillan, K. J., and Moore, M. W. (1996) Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature 380, 439-442.
-
(1996)
Nature
, vol.380
, pp. 439-442
-
-
Ferrara, N.1
Carver Moore, K.2
Chen, H.3
Dowd, M.4
Lu, L.5
O Shea, K.S.6
Powell, B.L.7
Hillan, K.J.8
Moore, M.W.9
-
25
-
-
0030831104
-
A requirement for Flk1 in primitive and definitive hematopoiesis and vasculogenesis
-
Shalaby, F., Ho, J., Stanford, W. L., Fischer, K. D., Schuh, A. C., Schwartz, L., Bernstein, A., and Rossant, J. (1997) A requirement for Flk1 in primitive and definitive hematopoiesis and vasculogenesis. Cell 89, 981-990.
-
(1997)
Cell
, vol.89
, pp. 981-990
-
-
Shalaby, F.1
Ho, J.2
Stanford, W.L.3
Fischer, K.D.4
Schuh, A.C.5
Schwartz, L.6
Bernstein, A.7
Rossant, J.8
-
26
-
-
0029006696
-
Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice
-
Shalaby, F., Rossant, J., Yamaguchi, T. P., Gertsenstein, M., Wu, X. F., Breitman, M. L., and Schuh, A. C. (1995) Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature 376, 62-66.
-
(1995)
Nature
, vol.376
, pp. 62-66
-
-
Shalaby, F.1
Rossant, J.2
Yamaguchi, T.P.3
Gertsenstein, M.4
Wu, X.F.5
Breitman, M.L.6
Schuh, A.C.7
-
27
-
-
0032764427
-
Increased hemangioblast commitment, not vascular disorganization, is the primary defect in flt-1 knock-out mice
-
Fong, G. H., Zhang, L., Bryce, D. M., and Peng, J. (1999) Increased hemangioblast commitment, not vascular disorganization, is the primary defect in flt-1 knock-out mice. Development 126, 3015-3025. (Pubitemid 29355693)
-
(1999)
Development
, vol.126
, Issue.13
, pp. 3015-3025
-
-
Fong, G.-H.1
Zhang, L.2
Bryce, D.-M.3
Peng, J.4
-
28
-
-
0029780465
-
Regulation of flt-1 expression during mouse embryogenesis suggests a role in the establishment of vascular endothelium
-
Fong, G. H., Klingensmith, J., Wood, C. R., Rossant, J., and Breitman, M. L. (1996) Regulation of flt-1 expression during mouse embryogenesis suggests a role in the establishment of vascular endothelium. Dev. Dyn. 207, 1-10.
-
(1996)
Dev. Dyn.
, vol.207
, pp. 1-10
-
-
Fong, G.H.1
Klingensmith, J.2
Wood, C.R.3
Rossant, J.4
Breitman, M.L.5
-
29
-
-
0029021660
-
Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
-
Fong, G. H., Rossant, J., Gertsenstein, M., and Breitman, M. L. (1995) Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature 376, 66-70.
-
(1995)
Nature
, vol.376
, pp. 66-70
-
-
Fong, G.H.1
Rossant, J.2
Gertsenstein, M.3
Breitman, M.L.4
-
30
-
-
4143136640
-
Vascular endothelial growth factor: Basic science and clinical progress
-
Ferrara, N. (2004) Vascular endothelial growth factor: basic science and clinical progress. Endocr. Rev. 25, 581-611.
-
(2004)
Endocr. Rev.
, vol.25
, pp. 581-611
-
-
Ferrara, N.1
-
31
-
-
0030603242
-
Molecular cloning of Quek 1 and 2, two quail vascular endothelial growth factor (VEGF) receptor-like molecules
-
DOI 10.1016/0378-1119(96)00159-X
-
Eichmann, A., Marcelle, C., Breant, C., and Le Douarin, N. M. (1996) Molecular cloning of Quek 1 and 2, two quail vascular endothelial growth factor (VEGF) receptor-like molecules. Gene 174, 3-8. (Pubitemid 26326844)
-
(1996)
Gene
, vol.174
, Issue.1
, pp. 3-8
-
-
Eichmann, A.1
Marcelle, C.2
Breant, C.3
Le Douarin, N.M.4
-
32
-
-
0036290513
-
Soluble Flt-1 (Soluble VEGFR-1), a potent natural antiangiogenic molecule in mammals, is phylogenetically conserved in avians
-
Yamaguchi, S., Iwata, K., and Shibuya, M. (2002) Soluble Flt-1 (Soluble VEGFR-1), a potent natural antiangiogenic molecule in mammals, is phylogenetically conserved in avians. Biochem. Biophys. Res. Commun. 291, 554-559.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.291
, pp. 554-559
-
-
Yamaguchi, S.1
Iwata, K.2
Shibuya, M.3
-
33
-
-
0032524043
-
The cloche and spadetail genes differentially affect hematopoiesis and vasculogenesis
-
Thompson, M. A., Ransom, D. G., Pratt, S. J., MacLennan, H., Kieran, M. W., Detrich, H. W. III, Vail, B., Huber, T. L., Paw, B., Brownlie, A. J., Oates, A. C., Fritz, A., Gates, M. A., Amores, A., Bahary, N., Talbot, W. S., Her, H., Beier, D. R., Postlethwait, J. H., and Zon, L. I. (1998) The cloche and spadetail genes differentially affect hematopoiesis and vasculogenesis. Dev. Biol. 197, 248-269.
-
(1998)
Dev. Biol.
, vol.197
, pp. 248-269
-
-
Thompson, M.A.1
Ransom, D.G.2
Pratt, S.J.3
MacLennan, H.4
Kieran, M.W.5
Detrich III, H.W.6
Vail, B.7
Huber, T.L.8
Paw, B.9
Brownlie, A.J.10
Oates, A.C.11
Fritz, A.12
Gates, M.A.13
Amores, A.14
Bahary, N.15
Talbot, W.S.16
Her, H.17
Beier, D.R.18
Postlethwait, J.H.19
Zon, L.I.20
more..
-
34
-
-
0030756681
-
Neovascularization of the Xenopus embryo
-
Cleaver, O., Tonissen, K. F., Saha, M. S., and Krieg, P. A. (1997) Neovascularization of the Xenopus embryo. Dev. Dyn. 210, 66-77.
-
(1997)
Dev. Dyn.
, vol.210
, pp. 66-77
-
-
Cleaver, O.1
Tonissen, K.F.2
Saha, M.S.3
Krieg, P.A.4
-
35
-
-
0032703582
-
The family of Caenorhabditis elegans tyrosine kinase receptors: Similarities and differences with mammalian receptors
-
Popovici, C., Roubin, R., Coulier, F., Pontarotti, P., and Birnbaum, D. (1999) The family of Caenorhabditis elegans tyrosine kinase receptors: similarities and differences with mammalian receptors. Genome Res. 9, 1026-1039.
-
(1999)
Genome Res.
, vol.9
, pp. 1026-1039
-
-
Popovici, C.1
Roubin, R.2
Coulier, F.3
Pontarotti, P.4
Birnbaum, D.5
-
36
-
-
0034755895
-
The Drosophila VEGF receptor homolog is expressed in hemocytes
-
Heino, T. I., Karpanen, T., Wahlstrom, G., Pulkkinen, M., Eriksson, U., Alitalo, K., and Roos, C. (2001) The Drosophila VEGF receptor homolog is expressed in hemocytes. Mech. Dev. 109, 69-77.
-
(2001)
Mech. Dev.
, vol.109
, pp. 69-77
-
-
Heino, T.I.1
Karpanen, T.2
Wahlstrom, G.3
Pulkkinen, M.4
Eriksson, U.5
Alitalo, K.6
Roos, C.7
-
37
-
-
0036806578
-
Vascular endothelial growth factor receptor family genes: When did the three genes phylogenetically segregate?
-
Shibuya, M. (2002) Vascular endothelial growth factor receptor family genes: when did the three genes phylogenetically segregate? Biol. Chem. 383, 1573-1579.
-
(2002)
Biol. Chem.
, vol.383
, pp. 1573-1579
-
-
Shibuya, M.1
-
38
-
-
36348994928
-
Duplicate VegfA genes and orthologues of the KDR receptor tyrosine kinase family mediate vascular development in the zebrafish
-
Bahary, N., Goishi, K., Stuckenholz, C., Weber, G., Leblanc, J., Schafer, C. A., Berman, S. S., Klagsbrun, M., and Zon, L. I. (2007) Duplicate VegfA genes and orthologues of the KDR receptor tyrosine kinase family mediate vascular development in the zebrafish. Blood 110, 3627-3636.
-
(2007)
Blood
, vol.110
, pp. 3627-3636
-
-
Bahary, N.1
Goishi, K.2
Stuckenholz, C.3
Weber, G.4
Leblanc, J.5
Schafer, C.A.6
Berman, S.S.7
Klagsbrun, M.8
Zon, L.I.9
-
39
-
-
22344446893
-
VEGF-PLCgamma1 pathway controls cardiac contractility in the embryonic heart
-
DOI 10.1101/gad.1319405
-
Rottbauer, W., Just, S., Wessels, G., Trano, N., Most, P., Katus, H. A., and Fishman, M. C. (2005) VEGF-PLCgamma1 pathway controls cardiac contractility in the embryonic heart. Genes Dev. 19, 1624-1634. (Pubitemid 41003004)
-
(2005)
Genes and Development
, vol.19
, Issue.13
, pp. 1624-1634
-
-
Rottbauer, W.1
Just, S.2
Wessels, G.3
Trano, N.4
Most, P.5
Katus, H.A.6
Fishman, M.C.7
-
40
-
-
34548427078
-
Early endocardial morphogenesis requires Scl/Tal1
-
Bussmann, J., Bakkers, J., and Schulte-Merker, S. (2007) Early endocardial morphogenesis requires Scl/Tal1. PLoS Genet 3, e140.
-
(2007)
PLoS Genet
, vol.3
-
-
Bussmann, J.1
Bakkers, J.2
Schulte-Merker, S.3
-
41
-
-
44949118532
-
Zebrafish VEGF receptors: A guideline to nomenclature
-
Bussmann, J., Lawson, N., Zon, L., and Schulte-Merker, S. (2008) Zebrafish VEGF receptors: a guideline to nomenclature. PLoS Genet 4, e1000064.
-
(2008)
PLoS Genet
, vol.4
-
-
Bussmann, J.1
Lawson, N.2
Zon, L.3
Schulte-Merker, S.4
-
42
-
-
0035812719
-
Guidance of cell migration by the Drosophila PDGF/VEGF receptor
-
DOI 10.1016/S0092-8674(01)00502-5
-
Duchek, P., Somogyi, K., Jekely, G., Beccari, S., and Rorth, P. (2001) Guidance of cell migration by the drosophila pdgf/vegf receptor. Cell 107, 17-26. (Pubitemid 32972034)
-
(2001)
Cell
, vol.107
, Issue.1
, pp. 17-26
-
-
Duchek, P.1
Somogyi, K.2
Jekely, G.3
Beccari, S.4
Rorth, P.5
-
43
-
-
0037155683
-
Developmental control of blood cell migration by the drosophila VEGF pathway
-
DOI 10.1016/S0092-8674(02)00676-1
-
Cho, N. K., Keyes, L., Johnson, E., Heller, J., Ryner, L., Karim, F., and Krasnow, M. A. (2002) Developmental control of blood cell migration by the drosophila VEGF pathway. Cell 108, 865-876. (Pubitemid 34327536)
-
(2002)
Cell
, vol.108
, Issue.6
, pp. 865-876
-
-
Cho, N.K.1
Keyes, L.2
Johnson, E.3
Heller, J.4
Ryner, L.5
Karim, F.6
Krasnow, M.A.7
-
44
-
-
0042203565
-
Sh2 and Ptb domains in tyrosine kinase signaling
-
Schlessinger, J. and Lemmon, M. A. (2003) Sh2 And Ptb domains in tyrosine kinase signaling. Sci. STKE 191, RE12.
-
(2003)
Sci. STKE
, vol.191
-
-
Schlessinger, J.1
Lemmon, M.A.2
-
45
-
-
0033915675
-
Ligand-binding sites in Ig-like domains of receptor tyrosine kinases
-
Wiesmann, C., Muller, Y. A., and de Vos, A. M. (2000) Ligand-binding sites in Ig-like domains of receptor tyrosine kinases. J. Mol. Med. 78, 247-260.
-
(2000)
J. Mol. Med.
, vol.78
, pp. 247-260
-
-
Wiesmann, C.1
Muller, Y.A.2
De Vos, A.M.3
-
46
-
-
0027414235
-
Soluble c-kit proteins and antireceptor monoclonal antibodies confine the binding site of the stem cell factor
-
Blechman, J. M., Lev, S., Brizzi, M. F., Leitner, O., Pegoraro, L., Givol, D., and Yarden, Y. (1993) Soluble c-kit proteins and antireceptor monoclonal antibodies confine the binding site of the stem cell factor. J. Biol. Chem. 268, 4399-4406.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 4399-4406
-
-
Blechman, J.M.1
Lev, S.2
Brizzi, M.F.3
Leitner, O.4
Pegoraro, L.5
Givol, D.6
Yarden, Y.7
-
47
-
-
0029550724
-
Structural aspects of receptor dimerization. c-kit as an example
-
Blechman, J. M. and Yarden, Y. (1995) Structural aspects of receptor dimerization. c-kit as an example. Ann. N Y Acad. Sci. 766, 344-362.
-
(1995)
Ann. N Y Acad. Sci.
, vol.766
, pp. 344-362
-
-
Blechman, J.M.1
Yarden, Y.2
-
48
-
-
0027218489
-
Dimerization of extracellular domains of platelet-derived growth factor receptors. a revised model of receptor-ligand interaction
-
Herren, B., Rooney, B., Weyer, K. A., Iberg, N., Schmid, G., and Pech, M. (1993) Dimerization of extracellular domains of platelet-derived growth factor receptors. A revised model of receptor-ligand interaction. J. Biol. Chem. 268, 15088-15095.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 15088-15095
-
-
Herren, B.1
Rooney, B.2
Weyer, K.A.3
Iberg, N.4
Schmid, G.5
Pech, M.6
-
49
-
-
0032080310
-
Requirements for binding and signaling of the kinase domain receptor for vascular endothelial growth factor
-
Fuh, G., Li, B., Crowley, C., Cunningham, B., and Wells, J. A. (1998) Requirements for binding and signaling of the kinase domain receptor for vascular endothelial growth factor. J. Biol. Chem. 273, 11197-11204.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 11197-11204
-
-
Fuh, G.1
Li, B.2
Crowley, C.3
Cunningham, B.4
Wells, J.A.5
-
50
-
-
0032553425
-
Mapping of the sites involved in ligand association and dissociation at the extracellular domain of the kinase insert domain-containing receptor for vascular endothelial growth factor
-
Shinkai, A., Ito, M., Anazawa, H., Yamaguchi, S., Shitara, K., and Shibuya, M. (1998) Mapping of the sites involved in ligand association and dissociation at the extracellular domain of the kinase insert domain-containing receptor for vascular endothelial growth factor. J. Biol. Chem. 273, 31283-31288.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 31283-31288
-
-
Shinkai, A.1
Ito, M.2
Anazawa, H.3
Yamaguchi, S.4
Shitara, K.5
Shibuya, M.6
-
51
-
-
0030814101
-
An antibody reactive with domain 4 of the platelet-derived growth factor beta receptor allows BB binding while inhibiting proliferation by impairing receptor dimerization
-
Shulman, T., Sauer, F. G., Jackman, R. M., Chang, C. N., and Landolfi, N. F. (1997) An antibody reactive with domain 4 of the platelet-derived growth factor beta receptor allows BB binding while inhibiting proliferation by impairing receptor dimerization. J. Biol. Chem. 272, 17400-17404.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 17400-17404
-
-
Shulman, T.1
Sauer, F.G.2
Jackman, R.M.3
Chang, C.N.4
Landolfi, N.F.5
-
52
-
-
0034640103
-
Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity
-
Plotnikov, A. N., Hubbard, S. R., Schlessinger, J., and Mohammadi, M. (2000) Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity. Cell 101, 413-424.
-
(2000)
Cell
, vol.101
, pp. 413-424
-
-
Plotnikov, A.N.1
Hubbard, S.R.2
Schlessinger, J.3
Mohammadi, M.4
-
53
-
-
0034718796
-
Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin
-
Pellegrini, L., Burke, D. F., von Delft, F., Mulloy, B., and Blundell, T. L. (2000) Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin. Nature 407, 1029-1034.
-
(2000)
Nature
, vol.407
, pp. 1029-1034
-
-
Pellegrini, L.1
Burke, D.F.2
Von Delft, F.3
Mulloy, B.4
Blundell, T.L.5
-
54
-
-
0034602719
-
Structural interactions of fibroblast growth factor receptor with its ligands
-
Stauber, D. J., DiGabriele, A. D., and Hendrickson, W. A. (2000) Structural interactions of fibroblast growth factor receptor with its ligands. Proc. Natl. Acad. Sci. USA 97, 49-54.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 49-54
-
-
Stauber, D.J.1
DiGabriele, A.D.2
Hendrickson, W.A.3
-
55
-
-
0033520472
-
Structural basis for FGF receptor dimerization and activation
-
DOI 10.1016/S0092-8674(00)80051-3
-
Plotnikov, A. N., Schlessinger, J., Hubbard, S. R., and Mohammadi, M. (1999) Structural basis for FGF receptor dimerization and activation. Cell 98, 641-650. (Pubitemid 29418955)
-
(1999)
Cell
, vol.98
, Issue.5
, pp. 641-650
-
-
Plotnikov, A.N.1
Schlessinger, J.2
Hubbard, S.R.3
Mohammadi, M.4
-
56
-
-
0033152903
-
A dimeric ternary complex of FGFR [correction of FGFR1], heparin and FGF-1 leads to an 'electrostatic sandwich' model for heparin binding
-
Huhtala, M. T., Pentikainen, O. T., and Johnson, M. S. (1999) A dimeric ternary complex of FGFR [correction of FGFR1], heparin and FGF-1 leads to an 'electrostatic sandwich' model for heparin binding. Structure 7, 699-709.
-
(1999)
Structure
, vol.7
, pp. 699-709
-
-
Huhtala, M.T.1
Pentikainen, O.T.2
Johnson, M.S.3
-
57
-
-
34447531743
-
Structural Basis for Activation of the Receptor Tyrosine Kinase KIT by Stem Cell Factor
-
DOI 10.1016/j.cell.2007.05.055, PII S0092867407007593
-
Yuzawa, S., Opatowsky, Y., Zhang, Z., Mandiyan, V., Lax, I., and Schlessinger, J. (2007) Structural basis for activation of the receptor tyrosine kinase Kit by stem cell factor. Cell 130, 323-334. (Pubitemid 47081138)
-
(2007)
Cell
, vol.130
, Issue.2
, pp. 323-334
-
-
Yuzawa, S.1
Opatowsky, Y.2
Zhang, Z.3
Mandiyan, V.4
Lax, I.5
Schlessinger, J.6
-
58
-
-
1642297115
-
The crystal structure of PlGF in complex with domain 2 of VEGFR1
-
Christinger, H. W., Fuh, G., de Vos, A. M., and Wiesmann, C. (2004) The crystal structure of PlGF in complex with domain 2 of VEGFR1. J. Biol. Chem. 279, 10382-10388.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 10382-10388
-
-
Christinger, H.W.1
Fuh, G.2
De Vos, A.M.3
Wiesmann, C.4
-
59
-
-
0030782410
-
Crystal structure at 1.7 a resolution of VEGF in complex with domain 2 of the Flt-1 receptor
-
Wiesmann, C., Fuh, G., Christinger, H. W., Eigenbrot, C., Wells, J. A., and de Vos, A. M. (1997) Crystal structure at 1.7 A resolution of VEGF in complex with domain 2 of the Flt-1 receptor. Cell 91, 695-704.
-
(1997)
Cell
, vol.91
, pp. 695-704
-
-
Wiesmann, C.1
Fuh, G.2
Christinger, H.W.3
Eigenbrot, C.4
Wells, J.A.5
De Vos, A.M.6
-
60
-
-
0034703039
-
Receptor-selective variants of human vascular endothelial growth factor. Generation and characterization
-
Li, B., Fuh, G., Meng, G., Xin, X., Gerritsen, M. E., Cunningham, B., and de Vos, A. M. (2000) Receptor-selective variants of human vascular endothelial growth factor. Generation and characterization. J. Biol. Chem. 275, 29823-29828.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 29823-29828
-
-
Li, B.1
Fuh, G.2
Meng, G.3
Xin, X.4
Gerritsen, M.E.5
Cunningham, B.6
De Vos, A.M.7
-
61
-
-
45549109855
-
Contacts between membrane proximal regions of the PDGF receptor ectodomain are required for receptor activation but not for receptor dimerization
-
Yang, Y., Yuzawa, S., and Schlessinger, J. (2008) Contacts between membrane proximal regions of the PDGF receptor ectodomain are required for receptor activation but not for receptor dimerization. Proc. Natl. Acad. Sci. USA 105, 7681-7686.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 7681-7686
-
-
Yang, Y.1
Yuzawa, S.2
Schlessinger, J.3
-
62
-
-
33847630758
-
Structure of a VEGF-VEGF receptor complex determined by electron microscopy
-
Ruch, C., Skiniotis, G., Steinmetz, M. O., Walz, T., and Ballmer-Hofer, K. (2007) Structure of a VEGF-VEGF receptor complex determined by electron microscopy. Nat. Struct. Mol. Biol. 14, 249-250.
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 249-250
-
-
Ruch, C.1
Skiniotis, G.2
Steinmetz, M.O.3
Walz, T.4
Ballmer-Hofer, K.5
-
63
-
-
0028890689
-
The fourth immunoglobulin domain of the stem cell factor receptor couples ligand binding to signal transduction
-
Blechman, J. M., Lev, S., Barg, J., Eisenstein, M., Vaks, B., Vogel, Z., Givol, D., and Yarden, Y. (1995) The fourth immunoglobulin domain of the stem cell factor receptor couples ligand binding to signal transduction. Cell 80, 103-113.
-
(1995)
Cell
, vol.80
, pp. 103-113
-
-
Blechman, J.M.1
Lev, S.2
Barg, J.3
Eisenstein, M.4
Vaks, B.5
Vogel, Z.6
Givol, D.7
Yarden, Y.8
-
64
-
-
0032566754
-
Role of immunoglobulin-like domains 2-4 of the platelet-derived growth factor alpha-receptor in ligand-receptor complex assembly
-
Miyazawa, K., Backstrom, G., Leppanen, O., Persson, C., Wernstedt, C., Hellman, U., Heldin, C. H., and Ostman, A. (1998) Role of immunoglobulin-like domains 2-4 of the platelet-derived growth factor alpha-receptor in ligand-receptor complex assembly. J. Biol. Chem. 273, 25495-25502.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 25495-25502
-
-
Miyazawa, K.1
Backstrom, G.2
Leppanen, O.3
Persson, C.4
Wernstedt, C.5
Hellman, U.6
Heldin, C.H.7
Ostman, A.8
-
65
-
-
0030977132
-
Immunoglobulin-like domain 4-mediated receptor-receptor interactions contribute to platelet-derived growth factor-induced receptor dimerization
-
Omura, T., Heldin, C. H., and Ostman, A. (1997) Immunoglobulin-like domain 4-mediated receptor-receptor interactions contribute to platelet-derived growth factor-induced receptor dimerization. J. Biol. Chem. 272, 12676-12682.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 12676-12682
-
-
Omura, T.1
Heldin, C.H.2
Ostman, A.3
-
66
-
-
0035877708
-
Kinase insert domain receptor (kdr) extracellular immunoglobulin-like domains 4-7 contain structural features that block receptor dimerization and vascular endothelial growth factor-induced signaling
-
Tao, Q., Backer, M. V., Backer, J. M., and Terman, B. I. (2001) Kinase insert domain receptor (kdr) extracellular immunoglobulin-like domains 4-7 contain structural features that block receptor dimerization and vascular endothelial growth factor-induced signaling. J. Biol. Chem. 276, 21916-21923.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 21916-21923
-
-
Tao, Q.1
Backer, M.V.2
Backer, J.M.3
Terman, B.I.4
-
67
-
-
0030614826
-
Oncogenic activation of the alphaPDGFR defines a domain that negatively regulates receptor dimerization
-
Uren, A., Yu, J. C., Karcaaltincaba, M., Pierce, J. H., and Heidaran, M. A. (1997) Oncogenic activation of the alphaPDGFR defines a domain that negatively regulates receptor dimerization. Oncogene 14, 157-162.
-
(1997)
Oncogene
, vol.14
, pp. 157-162
-
-
Uren, A.1
Yu, J.C.2
Karcaaltincaba, M.3
Pierce, J.H.4
Heidaran, M.A.5
-
68
-
-
0027203585
-
Specific short transmembrane sequences can inhibit transformation by the mutant neu growth factor receptor in vitro and in vivo
-
Lofts, F. J., Hurst, H. C., Sternberg, M. J., and Gullick, W. J. (1993) Specific short transmembrane sequences can inhibit transformation by the mutant neu growth factor receptor in vitro and in vivo. Oncogene 8, 2813-2820.
-
(1993)
Oncogene
, vol.8
, pp. 2813-2820
-
-
Lofts, F.J.1
Hurst, H.C.2
Sternberg, M.J.3
Gullick, W.J.4
-
69
-
-
0029881315
-
Strong hydrogen bonding interactions involving a buried glutamic acid in the transmembrane sequence of the neu/erbB-2 receptor
-
Smith, S. O., Smith, C. S., and Bormann, B. J. (1996) Strong hydrogen bonding interactions involving a buried glutamic acid in the transmembrane sequence of the neu/erbB-2 receptor. Nat. Struct. Biol. 3, 252-258.
-
(1996)
Nat. Struct. Biol.
, vol.3
, pp. 252-258
-
-
Smith, S.O.1
Smith, C.S.2
Bormann, B.J.3
-
70
-
-
0026569360
-
Three dimensional structure of the transmembrane region of the proto-oncogenic and oncogenic forms of the neu protein
-
Gullick, W. J., Bottomley, A. C., Lofts, F. J., Doak, D. G., Mulvey, D., Newman, R., Crumpton, M. J., Sternberg, M. J., and Campbell, I. D. (1992) Three dimensional structure of the transmembrane region of the proto-oncogenic and oncogenic forms of the neu protein. EMBO J. 11, 43-48.
-
(1992)
EMBO J.
, vol.11
, pp. 43-48
-
-
Gullick, W.J.1
Bottomley, A.C.2
Lofts, F.J.3
Doak, D.G.4
Mulvey, D.5
Newman, R.6
Crumpton, M.J.7
Sternberg, M.J.8
Campbell, I.D.9
-
71
-
-
0033786730
-
Rotational coupling of the transmembrane and kinase domains of the neu receptor tyrosine kinase
-
Bell, C. A., Tynan, J. A., Hart, K. C., Meyer, A. N., Robertson, S. C., and Donoghue, D. J. (2000) Rotational coupling of the transmembrane and kinase domains of the neu receptor tyrosine kinase. Mol. Biol. Cell 11, 3589-3599.
-
(2000)
Mol. Biol. Cell
, vol.11
, pp. 3589-3599
-
-
Bell, C.A.1
Tynan, J.A.2
Hart, K.C.3
Meyer, A.N.4
Robertson, S.C.5
Donoghue, D.J.6
-
72
-
-
0035979763
-
Activation of preformed EGF receptor dimers by ligand-induced rotation of the transmembrane domain
-
Moriki, T., Maruyama, H., and Maruyama, I. N. (2001) Activation of preformed EGF receptor dimers by ligand-induced rotation of the transmembrane domain. J. Mol. Biol. 311, 1011-1026.
-
(2001)
J. Mol. Biol.
, vol.311
, pp. 1011-1026
-
-
Moriki, T.1
Maruyama, H.2
Maruyama, I.N.3
-
73
-
-
0030969251
-
Transmembrane domain sequence requirements for activation of the p185c-neu receptor tyrosine kinase
-
Chen, L. I., Webster, M. K., Meyer, A. N., and Donoghue, D. J. (1997) Transmembrane domain sequence requirements for activation of the p185c-neu receptor tyrosine kinase. J. Cell Biol. 137, 619-631.
-
(1997)
J. Cell Biol.
, vol.137
, pp. 619-631
-
-
Chen, L.I.1
Webster, M.K.2
Meyer, A.N.3
Donoghue, D.J.4
-
74
-
-
0035963317
-
Identification of the transmembrane dimer interface of the bovine papillomavirus E5 protein
-
Mattoon, D., Gupta, K., Doyon, J., Loll, P. J., and DiMaio, D. (2001) Identification of the transmembrane dimer interface of the bovine papillomavirus E5 protein. Oncogene 20, 3824-3834.
-
(2001)
Oncogene
, vol.20
, pp. 3824-3834
-
-
Mattoon, D.1
Gupta, K.2
Doyon, J.3
Loll, P.J.4
DiMaio, D.5
-
75
-
-
0033835969
-
The platelet-derived growth factor beta receptor as a target of the bovine papillomavirus E5 protein
-
DiMaio, D., Lai, C. C., and Mattoon, D. (2000) The platelet-derived growth factor beta receptor as a target of the bovine papillomavirus E5 protein. Cytokine Growth Factor Rev. 11, 283-293.
-
(2000)
Cytokine Growth Factor Rev.
, vol.11
, pp. 283-293
-
-
DiMaio, D.1
Lai, C.C.2
Mattoon, D.3
-
76
-
-
0028338904
-
Cellular transformation by a transmembrane peptide: Structural requirements for the bovine papillomavirus E5 oncoprotein
-
Meyer, A. N., Xu, Y. F., Webster, M. K., Smith, A. E., and Donoghue, D. J. (1994) Cellular transformation by a transmembrane peptide: structural requirements for the bovine papillomavirus E5 oncoprotein. Proc. Natl. Acad. Sci. USA 91, 4634-4638.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 4634-4638
-
-
Meyer, A.N.1
Xu, Y.F.2
Webster, M.K.3
Smith, A.E.4
Donoghue, D.J.5
-
77
-
-
0033790332
-
E3-13.7 integral membrane proteins encoded by human adenoviruses alter epidermal growth factor receptor trafficking by interacting directly with receptors in early endosomes
-
Crooks, D., Kil, S. J., McCaffery, J. M., and Carlin, C. (2000) E3-13.7 integral membrane proteins encoded by human adenoviruses alter epidermal growth factor receptor trafficking by interacting directly with receptors in early endosomes. Mol. Biol. Cell 11, 3559-3572.
-
(2000)
Mol. Biol. Cell
, vol.11
, pp. 3559-3572
-
-
Crooks, D.1
Kil, S.J.2
McCaffery, J.M.3
Carlin, C.4
-
78
-
-
3042724865
-
Transmembrane peptides as inhibitors of ErbB receptor signaling
-
Bennasroune, A., Fickova, M., Gardin, A., Dirrig-Grosch, S., Aunis, D., Cremel, G., and Hubert, P. (2004) Transmembrane peptides as inhibitors of ErbB receptor signaling. Mol. Biol. Cell 15, 3464-3474.
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 3464-3474
-
-
Bennasroune, A.1
Fickova, M.2
Gardin, A.3
Dirrig-Grosch, S.4
Aunis, D.5
Cremel, G.6
Hubert, P.7
-
79
-
-
26944493862
-
Model for growth hormone receptor activation based on subunit rotation within a receptor dimer
-
Brown, R. J., Adams, J. J., Pelekanos, R. A., Wan, Y., McKinstry, W. J., Palethorpe, K., Seeber, R. M., Monks, T. A., Eidne, K. A., Parker, M. W., and Waters, M. J. (2005) Model for growth hormone receptor activation based on subunit rotation within a receptor dimer. Nat. Struct. Mol. Biol. 12, 814-821.
-
(2005)
Nat. Struct. Mol. Biol.
, vol.12
, pp. 814-821
-
-
Brown, R.J.1
Adams, J.J.2
Pelekanos, R.A.3
Wan, Y.4
McKinstry, W.J.5
Palethorpe, K.6
Seeber, R.M.7
Monks, T.A.8
Eidne, K.A.9
Parker, M.W.10
Waters, M.J.11
-
80
-
-
0034595635
-
Receptor chimeras indicate that the vascular endothelial growth factor receptor-1 (VEGFR-1) modulates mitogenic activity of VEGFR-2 in endothelial cells
-
Rahimi, N., Dayanir, V., and Lashkari, K. (2000) Receptor chimeras indicate that the vascular endothelial growth factor receptor-1 (VEGFR-1) modulates mitogenic activity of VEGFR-2 in endothelial cells. J. Biol. Chem. 275, 16986-16992.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 16986-16992
-
-
Rahimi, N.1
Dayanir, V.2
Lashkari, K.3
-
81
-
-
44649150218
-
Autoregulation by the juxtamembrane region of the human ephrin receptor tyrosine kinase A3 (EphA3)
-
Davis, T. L., Walker, J. R., Loppnau, P., Butler-Cole, C., lali-Hassani, A., and Dhe-Paganon, S. (2008) Autoregulation by the juxtamembrane region of the human ephrin receptor tyrosine kinase A3 (EphA3). Structure 16, 873-884.
-
(2008)
Structure
, vol.16
, pp. 873-884
-
-
Davis, T.L.1
Walker, J.R.2
Loppnau, P.3
Butler-Cole, C.4
Lali-Hassani, A.5
Dhe-Paganon, S.6
-
82
-
-
34250895565
-
Autoinhibition of the insulin-like growth factor I receptor by the juxtamembrane region
-
Craddock, B. P., Cotter, C., and Miller, W. T. (2007) Autoinhibition of the insulin-like growth factor I receptor by the juxtamembrane region. FEBS Lett 581, 3235-3240.
-
(2007)
FEBS Lett
, vol.581
, pp. 3235-3240
-
-
Craddock, B.P.1
Cotter, C.2
Miller, W.T.3
-
83
-
-
44949190466
-
Detailed conformational dynamics of juxtamembrane region and activation loop in c-Kit kinase activation process
-
Zou, J., Wang, Y. D., Ma, F. X., Xiang, M. L., Shi, B., Wei, Y. Q., and Yang, S. Y. (2008) Detailed conformational dynamics of juxtamembrane region and activation loop in c-Kit kinase activation process. Proteins 72, 323-332.
-
(2008)
Proteins
, vol.72
, pp. 323-332
-
-
Zou, J.1
Wang, Y.D.2
Ma, F.X.3
Xiang, M.L.4
Shi, B.5
Wei, Y.Q.6
Yang, S.Y.7
-
84
-
-
0037405026
-
Autoinhibition of the kit receptor tyrosine kinase by the cytosolic juxtamembrane region
-
Chan, P. M., Ilangumaran, S., La, R. J., Chakrabartty, A., and Rottapel, R. (2003) Autoinhibition of the kit receptor tyrosine kinase by the cytosolic juxtamembrane region. Mol. Cell Biol. 23, 3067-3078.
-
(2003)
Mol. Cell Biol.
, vol.23
, pp. 3067-3078
-
-
Chan, P.M.1
Ilangumaran, S.2
La, R.J.3
Chakrabartty, A.4
Rottapel, R.5
-
85
-
-
0042090223
-
Signal transduction by several KIT juxtamembrane domain mutations
-
Casteran, N., De Sepulveda, P., Beslu, N., Aoubala, M., Letard, S., Lecocq, E., Rottapel, R., and Dubreuil, P. (2003) Signal transduction by several KIT juxtamembrane domain mutations. Oncogene 22, 4710-4722.
-
(2003)
Oncogene
, vol.22
, pp. 4710-4722
-
-
Casteran, N.1
De Sepulveda, P.2
Beslu, N.3
Aoubala, M.4
Letard, S.5
Lecocq, E.6
Rottapel, R.7
Dubreuil, P.8
-
86
-
-
0034254273
-
A repressor sequence in the juxtamembrane domain of Flt-1 (VEGFR-1) constitutively inhibits vascular endothelial growth factor-dependent phosphatidylinositol 30-kinase activation and endothelial cell migration
-
Gille, H., Kowalski, J., Yu, L., Chen, H., Pisabarro, M. T., Davis, S. T., and Ferrara, N. (2000) A repressor sequence in the juxtamembrane domain of Flt-1 (VEGFR-1) constitutively inhibits vascular endothelial growth factor-dependent phosphatidylinositol 30-kinase activation and endothelial cell migration. EMBO J. 19, 4064-4073.
-
(2000)
EMBO J.
, vol.19
, pp. 4064-4073
-
-
Gille, H.1
Kowalski, J.2
Yu, L.3
Chen, H.4
Pisabarro, M.T.5
Davis, S.T.6
Ferrara, N.7
-
87
-
-
0033103867
-
Crystal structure of the kinase domain of human vascular endothelial growth factor receptor 2: A key enzyme in angiogenesis
-
McTigue, M. A., Wickersham, J. A., Pinko, C., Showalter, R. E., Parast, C. V., Tempczyk, R. A., Gehring, M. R., Mroczkowski, B., Kan, C. C., Villafranca, J. E., and Appelt, K. (1999) Crystal structure of the kinase domain of human vascular endothelial growth factor receptor 2: a key enzyme in angiogenesis. Structure 7, 319-330.
-
(1999)
Structure
, vol.7
, pp. 319-330
-
-
McTigue, M.A.1
Wickersham, J.A.2
Pinko, C.3
Showalter, R.E.4
Parast, C.V.5
Tempczyk, R.A.6
Gehring, M.R.7
Mroczkowski, B.8
Kan, C.C.9
Villafranca, J.E.10
Appelt, K.11
-
88
-
-
2942594298
-
Juxtamembrane autoinhibition in receptor tyrosine kinases
-
Hubbard, S. R. (2004) Juxtamembrane autoinhibition in receptor tyrosine kinases. Nat. Rev. Mol. Cell Biol. 5, 464-471.
-
(2004)
Nat. Rev. Mol. Cell Biol.
, vol.5
, pp. 464-471
-
-
Hubbard, S.R.1
-
89
-
-
0035929146
-
Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region
-
Wybenga-Groot, L. E., Baskin, B., Ong, S. H., Tong, J., Pawson, T., and Sicheri, F. (2001) Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region. Cell 106, 745-757.
-
(2001)
Cell
, vol.106
, pp. 745-757
-
-
Wybenga-Groot, L.E.1
Baskin, B.2
Ong, S.H.3
Tong, J.4
Pawson, T.5
Sicheri, F.6
-
90
-
-
33847281812
-
The 2.7 a crystal structure of the autoinhibited human c-Fms kinase domain
-
Walter, M., Lucet, I. S., Patel, O., Broughton, S. E., Bamert, R., Williams, N. K., Fantino, E., Wilks, A. F., and Rossjohn, J. (2007) The 2.7 a crystal structure of the autoinhibited human c-Fms kinase domain. J. Mol. Biol. 367, 839-847.
-
(2007)
J. Mol. Biol.
, vol.367
, pp. 839-847
-
-
Walter, M.1
Lucet, I.S.2
Patel, O.3
Broughton, S.E.4
Bamert, R.5
Williams, N.K.6
Fantino, E.7
Wilks, A.F.8
Rossjohn, J.9
-
91
-
-
36749011864
-
Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface
-
Zhang, X., Pickin, K. A., Bose, R., Jura, N., Cole, P. A., and Kuriyan, J. (2007) Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface. Nature 450, 741-744.
-
(2007)
Nature
, vol.450
, pp. 741-744
-
-
Zhang, X.1
Pickin, K.A.2
Bose, R.3
Jura, N.4
Cole, P.A.5
Kuriyan, J.6
-
92
-
-
33745002702
-
An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor
-
Zhang, X., Gureasko, J., Shen, K., Cole, P. A., and Kuriyan, J. (2006) An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor. Cell 125, 1137-1149.
-
(2006)
Cell
, vol.125
, pp. 1137-1149
-
-
Zhang, X.1
Gureasko, J.2
Shen, K.3
Cole, P.A.4
Kuriyan, J.5
-
93
-
-
33751539464
-
Protein-protein interactions in the allosteric regulation of protein kinases
-
Pellicena, P. and Kuriyan, J. (2006) Protein-protein interactions in the allosteric regulation of protein kinases. Curr. Opin. Struct. Biol. 16, 702-709.
-
(2006)
Curr. Opin. Struct. Biol.
, vol.16
, pp. 702-709
-
-
Pellicena, P.1
Kuriyan, J.2
-
94
-
-
55749110742
-
Neuropilin-1 in regulation of VEGF-induced activation of p38MAPK and endothelial cell organization
-
Kawamura, H., Li, X., Goishi, K., van Meeteren, L. A., Jakobsson, L., Cebe-Suarez, S., Shimizu, A., Edholm, D., Ballmer-Hofer, K., Kjellen, L., Klagsbrun, M., and Claesson-Welsh, L. (2008) Neuropilin-1 in regulation of VEGF-induced activation of p38MAPK and endothelial cell organization. Blood 112, 3638-3649.
-
(2008)
Blood
, vol.112
, pp. 3638-3649
-
-
Kawamura, H.1
Li, X.2
Goishi, K.3
Van Meeteren, L.A.4
Jakobsson, L.5
Cebe-Suarez, S.6
Shimizu, A.7
Edholm, D.8
Ballmer-Hofer, K.9
Kjellen, L.10
Klagsbrun, M.11
Claesson-Welsh, L.12
-
95
-
-
33748479489
-
A VEGF-a splice variant defective for heparan sulfate and neuropilin-1 binding shows attenuated signaling through VEGFR-2
-
Cébe-Suarez, S., Pieren, M., Cariolato, L., Arn, S., Hoffmann, U., Bogucki, A., Manlius, C., Wood, J., and Ballmer-Hofer, K. (2006) A VEGF-a splice variant defective for heparan sulfate and neuropilin-1 binding shows attenuated signaling through VEGFR-2. Cell Mol. Life Sci. 63, 2067-2077.
-
(2006)
Cell Mol. Life Sci.
, vol.63
, pp. 2067-2077
-
-
Cébe-Suarez, S.1
Pieren, M.2
Cariolato, L.3
Arn, S.4
Hoffmann, U.5
Bogucki, A.6
Manlius, C.7
Wood, J.8
Ballmer-Hofer, K.9
-
96
-
-
49649088463
-
Vascular endothelial growth factor (VEGF)-A165b is a weak in vitro agonist for VEGF receptor-2 due to lack of coreceptor binding and deficient regulation of kinase activity
-
Kawamura, H., Li, X., Harper, S. J., Bates, D. O., and Claesson-Welsh, L. (2008) Vascular endothelial growth factor (VEGF)-A165b is a weak in vitro agonist for VEGF receptor-2 due to lack of coreceptor binding and deficient regulation of kinase activity. Cancer Res. 68, 4683-4692.
-
(2008)
Cancer Res.
, vol.68
, pp. 4683-4692
-
-
Kawamura, H.1
Li, X.2
Harper, S.J.3
Bates, D.O.4
Claesson-Welsh, L.5
|