Relative positioning of diazepam in the benzodiazepine-binding-pocket of GABAA receptors

Journal of Neurochemistry

Volumn 111, Issue 5, 2009, Pages 1264-1273

  Tan, Kelly R ^a   Baur, Roland ^a   Charon, Sébastien ^b   Goeldner, Maurice ^b   Sigel, Erwin ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

Benzodiazepines; Diazepam; GABA; GABAA receptor

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; BENZODIAZEPINE; CYSTEINE; DIAZEPAM; ISOTHIOCYANIC ACID; NITRAZEPAM;

ARTICLE; BRAIN; CLINICAL PRACTICE; DRUG BINDING SITE; DRUG MECHANISM; NONHUMAN; PRIORITY JOURNAL;

ALLOSTERIC REGULATION; ANIMALS; ANTI-ANXIETY AGENTS; BENZODIAZEPINES; BINDING SITES; BIOPHYSICS; CELL LINE, TRANSFORMED; CYSTEINE; DIAZEPAM; DIZOCILPINE MALEATE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; FLUMAZENIL; GABA MODULATORS; GAMMA-AMINOBUTYRIC ACID; HUMANS; MEMBRANE POTENTIALS; OOCYTES; POINT MUTATION; PROTEIN BINDING; RECEPTORS, GABA-A; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION; XENOPUS;

EID: 70350764850     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2009.06419.x     Document Type: Article

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