The preterm parturition syndrome and its implications for understanding the biology, risk assessment, diagnosis, treatment and prevention of preterm birth

Journal of Maternal-Fetal and Neonatal Medicine

Volumn 22, Issue SUPPL.2, 2009, Pages 5-23

  Gotsch, Francesca ^a,b   Romero, Roberto ^a,c,d   Erez, Offer ^a,b,d   Vaisbuch, Edi ^a,b,d   Kusanovic, Juan Pedro ^a,b,d   Mazaki Tovi, Shali ^a,b,d   Kim, Sun Kwon ^a,b   Hassan, Sonia ^a,b,d   Yeo, Lami ^a,b,d  

^a Perinatology Research Branch   (United States)

^b NICHDNIHDHHS   (United States)

^c WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d HUTZEL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGY; BIOLOGY; CLINICAL FEATURE; CONGENITAL MALFORMATION; DECIDUA; DIAGNOSTIC TEST; DISEASE CLASSIFICATION; ENDOCRINE DISEASE; GESTATIONAL AGE; GRAFT REJECTION; HUMAN; INFLAMMATION; INTRAUTERINE INFECTION; LIVER FATTY DEGENERATION; PATHOPHYSIOLOGY; PERINATAL MORBIDITY; PERINATAL MORTALITY; PREECLAMPSIA; PREMATURE LABOR; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT; RISK FACTOR; SMALL FOR DATE INFANT; ULTRASOUND; UTERINE CERVIX CERCLAGE; UTERINE CERVIX RIPENING; UTERUS CONTRACTILITY;

EXTRAEMBRYONIC MEMBRANES; FEMALE; FETAL DISEASES; GESTATIONAL AGE; HUMANS; INFANT; INFANT MORTALITY; INFANT, NEWBORN; INFANT, PREMATURE; INFANT, PREMATURE, DISEASES; INFLAMMATION; OBSTETRIC LABOR, PREMATURE; PARTURITION; PREGNANCY; PREMATURE BIRTH; RISK ASSESSMENT; SYNDROME; UTERINE CERVICAL DISEASES; UTERINE CONTRACTION; UTERINE DISEASES;

EID: 70350666482     PISSN: 14767058     EISSN: 14764954     Source Type: Journal    
DOI: 10.1080/14767050902860690     Document Type: Review

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147. Hertelendy F, Rastogi P, Molnar M, Romero R. Interleukin- 1beta-induced prostaglandin E2 production in human myometrial cells: role of a pertussis toxin-sensitive component. Am J Reprod Immunol 2001;45:142-147.
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161. Lee SE, Romero R, Kim CJ, Shim SS, Yoon BH. Funisitis in term pregnancy is associated with microbial invasion of the amniotic cavity and intra-amniotic inflammation. J Matern Fetal Neonatal Med 2006;19:693-697.
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164. Maymon E, Romero R, Pacora P, Gervasi MT, Edwin SS, Gomez R, Seubert DE. Matrilysin (matrix metalloproteinase 7) in parturition, premature rupture of membranes, and intrauterine infection. Am J Obstet Gynecol 2000;182:1545-1553. (Pubitemid 30437428)
165. Maymon E, Romero R, Pacora P, Gomez R, Athayde N, Edwin S, Yoon BH. Human neutrophil collagenase (matrix metalloproteinase 8) in parturition, premature rupture of the membranes, and intrauterine infection. Am J Obstet Gynecol 2000;183:94-99. (Pubitemid 30626034)
166. Maymon E, Romero R, Pacora P, Gervasi MT, Gomez R, Edwin SS, Yoon BH. Evidence of in vivo differential bioavailability of the active forms of matrix metalloproteinases 9 and 2 in parturition, spontaneous rupture of membranes, and intra-amniotic infection. Am J Obstet Gynecol 2000;183:887-894.
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199. Romero R, Mazor M, Wu YK, Avila C, Oyarzun E, Mitchell MD. Bacterial endotoxin and tumor necrosis factor stimulate prostaglandin production by human decidua. Prostaglandins Leukot Essent Fatty Acids 1989;37:183-186.
200. Romero R, Sirtori M, Oyarzun E, Avila C, Mazor M, Callahan R, Sabo V, Athanassiadis AP, Hobbins JC. Infection and labor. V. Prevalence, microbiology, and clinical significance of intraamniotic infection in women with preterm labor and intact membranes. Am J Obstet Gynecol 1989;161:817-824.
201. Romero R, Oyarzun E, Mazor M, Sirtori M, Hobbins JC, Bracken M. Meta-analysis of the relationship between asymptomatic bacteriuria and preterm delivery/low birth weight. Obstet Gynecol 1989;73:576-582.
202. Romero R, Brody DT, Oyarzun E, Mazor M, Wu YK, Hobbins JC, Durum SK. Infection and labor. III. Interleukin- 1: a signal for the onset of parturition. Am J Obstet Gynecol 1989;160:1117-1123.
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205. Romero R, Durum S, Dinarello CA, Oyarzun E, Hobbins JC, Mitchell MD. Interleukin-1 stimulates prostaglandin biosynthesis by human amnion. Prostaglandins 1989;37:13-22.
206. Romero R, Wu YK, Brody DT, Oyarzun E, Duff GW, Durum SK. Human decidua: a source of interleukin-1. Obstet Gynecol 1989;73:31-34.
207. Romero R, Avila C, Santhanam U, Sehgal PB. Amniotic fluid interleukin 6 in preterm labor. Association with infection. J Clin Invest 1990;85:1392-1400.
208. Romero R, Parvizi ST, Oyarzun E, Mazor M, Wu YK, Avila C, Athanassiadis AP, Mitchell MD. Amniotic fluid interleukin- 1 in spontaneous labor at term. J Reprod Med 1990;35:235-238.
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212. Himes KP, Simhan HN. Risk of recurrent preterm birth and placental pathology. Obstet Gynecol 2008;112(1):121-126.
213. Romero R, Shamma F, Avila C, Jimenez C, Callahan R, Nores J, et al. Infection and labor. VI. Prevalence, microbiology, and clinical significance of intraamniotic infection in twin gestations with preterm labor. Am J Obstet Gynecol 1990;163:757-761.
214. Romero R, Salafia CM, Athanassiadis AP, Hanaoka S, Mazor M, Sepulveda W, Bracken MD. The relationship between acute inflammatory lesions of the preterm placenta and amniotic fluid microbiology. Am J Obstet Gynecol 1992;166:1382-1388.
215. Romero R, Gonzalez R, Sepulveda W, Brandt F, Ramirez M, Sorokin Y, Mazor M, Treadwell MC, Cotton DB. Infection and labor. VIII. Microbial invasion of the amniotic cavity in patients with suspected cervical incompetence: prevalence and clinical significance. Am J Obstet Gynecol 1992;167:1086-1091.
216. Romero R, Munoz H, Gomez R, Ramirez M, Araneda H, Cutright J, Wolf N, Cotton D, Fidel PL. Antibiotic therapy reduces the rate of infection-induced preterm delivery and perinatal mortality. Am J Obstet Gynecol 1994;170:390.
217. Romero R, Munoz H, Gomez R, Sherer DM, Ghezzi F, Gibbs RS, et al. Two thirds of spontaneous abortion/fetal deaths after genetic amniocentesis are the result of a preexisting sub-clinical inflammatory process of the amniotic cavity. Am J Obstet Gynecol 1995;172:S261.
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220. Jeffcoat MK, Geurs NC, Reddy MS, Goldenberg RL, Hauth JC. Current evidence regarding periodontal disease as a risk factor in preterm birth. Ann Periodontol 2001;6:183-188.
221. Yoon BH, Oh SY, Romero R, Shim SS, Han SY, Park JS, Jun JK. An elevated amniotic fluid matrix metalloproteinase- 8 level at the time of mid-trimester genetic amniocentesis is a risk factor for spontaneous preterm delivery. Am J Obstet Gynecol 2001;185:1162-1167.
222. Wang H, Hirsch E. Bacterially-induced preterm labor and regulation of prostaglandin-metabolizing enzyme expression in mice: the role of toll-like receptor 4. Biol Reprod 2003;69:1957-1963.
223. Fidel P, Ghezzi F, Romero R, Chaiworapongsa T, Espinoza J, Cutright J, Wolf N, Gomez R. The effect of antibiotic therapy on intrauterine infection-induced preterm parturition in rabbits. J Matern Fetal Neonatal Med 2003;14: 57-64.
224. Elovitz MA, Mrinalini C. Animal models of preterm birth. Trends Endocrinol Metab 2004;15:479-487.
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227. Xiong X, Buekens P, Fraser WD, Beck J, Offenbacher S. Periodontal disease and adverse pregnancy outcomes: a systematic review. BJOG 2006;113:135-143.
228. Romero R, Avila C, Brekus CA, Morotti R. The role of systemic and intrauterine infection in preterm parturition. Ann N Y Acad Sci 1991;622:355-375.
229. Romero R, Ceska M, Avila C, Mazor M, Behnke E, Lindley I. Neutrophil attractant/activating peptide-1/interleukin-8 in term and preterm parturition. Am J Obstet Gynecol 1991;165:813-820.
230. Romero R, Mazor M, Manogue K, Oyarzun E, Cerami A. Human decidua: a source of cachectin-tumor necrosis factor. Eur J Obstet Gynecol Reprod Biol 1991;41:123-127.
231. Romero R, Mazor M, Tartakovsky B. Systemic administration of interleukin-1 induces preterm parturition in mice. Am J Obstet Gynecol 1991;165:969-971.
232. Romero R, Mazor M, Sepulveda W, Avila C, Copeland D, Williams J. Tumor necrosis factor in preterm and term labor. Am J Obstet Gynecol 1992;166:1576-1587.
233. Romero R, Mazor M, Brandt F, Sepulveda W, Avila C, Cotton DB, Dinarello CA. Interleukin-1 alpha and interleukin- 1 beta in preterm and term human parturition. Am J Reprod Immunol 1992;27:117-123.
234. Romero R, Tartakovsky B. The natural interleukin-1 receptor antagonist prevents interleukin-1-induced preterm delivery in mice. Am J Obstet Gynecol 1992;167:1041-1045.
235. Romero R, Sepulveda W, Kenney JS, Archer LE, Allison AC, Sehgal PB. Interleukin 6 determination in the detection of microbial invasion of the amniotic cavity. Ciba Found Symp 1992;167:205-220.
236. Romero R, Sepulveda W, Mazor M, Brandt F, Cotton DB, Dinarello CA, Mitchell MD. The natural interleukin-1 receptor antagonist in term and preterm parturition. Am J Obstet Gynecol 1992;167:863-872.
237. Romero R, Mazor M, Morrotti R, Avila C, Oyarzun E, Insunza A, Parra M, Behnke E, Montiel F, Cassell GH. Infection and labor. VII. Microbial invasion of the amniotic cavity in spontaneous rupture of membranes at term. Am J Obstet Gynecol 1992;166:129-133.
238. Romero R, Sepulveda W, Baumann P, Yoon BH, Brandt F, Gomez R, Mazor M, Sorokin Y, Cotton D. The preterm labor syndrome: Biochemical, cytologic, immunologic, pathologic, microbiologic, and clinical evidence that preterm labor is a heterogeneous disease. Am J Obstet Gynecol 1993;168:288.
239. Romero R, Nores J, Mazor M, Sepulveda W, Oyarzun E, Parra M, Insunza A, Montiel F, Behnke E, Cassell GH. Microbial invasion of the amniotic cavity during term labor. Prevalence and clinical significance. J Reprod Med 1993;38:543-548.
240. Romero R, Yoon BH, Kenney JS, Gomez R, Allison AC, Sehgal PB. Amniotic fluid interleukin-6 determinations are of diagnostic and prognostic value in preterm labor. Am J Reprod Immunol 1993;30:167-183.
241. Romero R, Yoon BH, Gonzalez R, Brandt F, Sepulveda W, Gomez R, et al. The clinical significance of microbial invasion of the amniotic cavity with mycoplasmas in patients with preterm PROM. Presented at the 40th Annual Meeting of the Society for Gynecologic Investigation, 31 March-3 April, 1993, Toronto, Ontario, Canada, p70, Abstract S4.
242. Romero R, Baumann P, Gomez R, Salafia C, Rittenhouse L, Barberio D, Behnke E, Cotton DB, Mitchell MD. The relationship between spontaneous rupture of membranes, labor, and microbial invasion of the amniotic cavity and amniotic fluid concentrations of prostaglandins and thromboxane B2 in term pregnancy. Am J Obstet Gynecol 1993;168:1654-1664.
243. Romero R, Sibai B, Caritis S, Paul R, Depp R, Rosen M, Klebanoff M, Sabo V, Evans J, Thom E, et al. Antibiotic treatment of preterm labor with intact membranes: a multicenter, randomized, double-blinded, placebo-controlled trial. Am J Obstet Gynecol 1993;169:764-774.
244. Romero R, Avila C, Sepulveda W, et al. The role of systemic and intrauterine infection in pretermlabor. In: Fuchs A, Fuchs F, Stubblefield P, editors. Preterm Birth: Causes, Prevention, and Management. New York: McGraw-Hill; 1993.
245. Romero R, Gomez R, Galasso M, Munoz H, Acosta L, Yoon BH, Svinarich D, Cotton DB. Macrophage inflammatory protein-1 alpha in term and preterm parturition: effect of microbial invasion of the amniotic cavity. Am J Reprod Immunol 1994;32:108-113.
246. Romero R, Gomez R, Galasso M, Mazor M, Berry SM, Quintero RA, Cotton DB. The natural interleukin-1 receptor antagonist in the fetal, maternal, and amniotic fluid compartments: the effect of gestational age, fetal gender, and intrauterine infection. Am J Obstet Gynecol 1994;171:912-921.
247. Romero R, Baumann P, Gonzalez R, Gomez R, Rittenhouse L, Behnke E, Mitchell MD. Amniotic fluid prostanoid concentrations increase early during the course of spontaneous labor at term. Am J Obstet Gynecol 1994;171:1613-1620.
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