Polymorphisms in the tumor necrosis factor alpha and interleukin 1-beta promoters with possible gene regulatory functions increase the risk of preterm birth

Acta Obstetricia et Gynecologica Scandinavica

Volumn 87, Issue 12, 2008, Pages 1285-1290

  Hollegaard, Mads Vilhelm ^a,b,c   Grove, Jakob ^b   Thorsen, Poul ^b,f   Wang, Xiaobin ^d   Mandrup, Susanne ^c   Christiansen, Michael ^a   Norgaard Pedersen, Bent ^a   Wojdemann, Karen R ^e   Tabor, Ann ^e   Attermann, Jorn ^b   Hougaard, David Michael ^a  

^a STATENS SERUM INSTITUT   (Denmark)

^b AARHUS UNIVERSITY   (Denmark)

^c UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^d NORTHWESTERN UNIVERSITY   (United States)

^e Rigshospitalet   (Denmark)

^f EMORY UNIVERSITY   (United States)

Author keywords

Cytokine; IL1B; IL6; Polymorphism; Preterm birth; TNFA

Indexed keywords

INTERLEUKIN 1BETA; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ALLELE; ARTICLE; CASE CONTROL STUDY; CAUCASIAN; CONTROLLED STUDY; FEMALE; GENE CONTROL; GENE SEQUENCE; GENETIC ASSOCIATION; GENOTYPE; HAPLOTYPE; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; PREMATURITY; PRIORITY JOURNAL; PROMOTER REGION; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; CASE-CONTROL STUDIES; FEMALE; GENOTYPE; HAPLOTYPES; HUMANS; INTERLEUKIN-1BETA; INTERLEUKIN-6; LOGISTIC MODELS; POLYMORPHISM, SINGLE NUCLEOTIDE; PREGNANCY; PREMATURE BIRTH; PROMOTER REGIONS, GENETIC; TRANSCRIPTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 57449084617     PISSN: 00016349     EISSN: 16000412     Source Type: Journal    
DOI: 10.1080/00016340802468340     Document Type: Article

References (23)

1. Nesin M. Genetic basis of preterm birth. Front Biosci. 2007;12:115-24.
2. Langhoff-Roos J, Kesmodel U, Jacobsson B, Rasmussen S, Vogel I. Spontaneous preterm delivery in primiparous women at low risk in Denmark: population based study. BMJ 2006 April 22;332:937-9.
3. Winkler M, Rath W. Changes in the cervical extracellular matrix during pregnancy and parturition. J Perinat Med. 1999;27:45-60.
4. Lockwood CJ, Kuczynski E. Risk stratification and pathological mechanisms in preterm delivery. Paediatr Perinat Epidemiol. 2001 July;15 Suppl 2:78-89.
5. Bahar AM, Ghalib HW, Moosa RA, Zaki ZM, Thomas C, Nabri OA. Maternal serum interleukin-6, interleukin-8, tumor necrosis factor-alpha and interferon-gamma in preterm labor. Acta Obstet Gynecol Scand. 2003 June;82:543-9.
6. Hollegaard MV, Bidwell JL. Cytokine gene polymorphism in human disease: on-line databases, Supplement 3. Genes Immun 2006 June;7:269-76.
7. Wojdemann KR, Shalmi AC, Christiansen M, Larsen SO, Sundberg K, Brocks V, Bang J, Norgaard-Pedersen B, Tabor A. Improved first-trimester Down syndrome screening performance by lowering the false-positive rate: a prospective study of 9941 low-risk women. Ultrasound Obstet Gynecol 2005 March;25:227-33.
8. Moore S, Ide M, Randhawa M, Walker JJ, Reid JG, Simpson NA. An investigation into the association among preterm birth, cytokine gene polymorphisms and periodontal disease. BJOG 2004 February;111:125-32.
9. Hartel C, Finas D, Ahrens P, Kattner E, Schaible T, Muller D, Segerer H, Albrecht K, Moller J, Diedrich K, Gopel W. Polymorphisms of genes involved in innate immunity: association with preterm delivery. Mol Hum Reprod 2004 December;10:911-5.
10. Mattar R, de SE, Daher S. Preterm delivery and cytokine gene polymorphisms. J Reprod Med 2006 April;51:317-20.
11. Amory JH, Adams KM, Lin MT, Hansen JA, Eschenbach DA, Hitti J. Adverse outcomes after preterm labor are associated with tumor necrosis factor-alpha polymorphism - 863, but not -308, in mother-infant pairs. Am J Obstet Gynecol. 2004 October;191:1362-7.
12. Engel SA, Erichsen HC, Savitz DA, Thorp J, Chanock SJ, Olshan AF. Risk of spontaneous preterm birth is associated with common proinflammatory cytokine polymorphisms. Epidemiology. 2005 July;16:469-77.
13. Chen H, Wilkins LM, Aziz N, Cannings C, Wyllie DH, Bingle C, Rogus J, Beck JD, Offenbacher S, Cork MJ, Rafie-Kolpin M, Hsieh CM, Kornman KS, Duff GW. Single nucleotide polymorphisms in the human interleukin-1B gene affect transcription according to haplotype context. Hum Mol Genet. 2006 February;15;15:519-29.
14. Rad R, Dossumbekova A, Neu B, Lang R, Bauer S, Saur D, Gerhard M, Prinz C. Cytokine gene polymorphisms influence mucosal cytokine expression, gastric inflammation, and host specific colonisation during Helicobacter pylori infection. Gut. 2004 August;53:1082-9.
15. Hall SK, Perregaux DG, Gabel CA, Woodworth T, Durham LK, Huizinga TW, Breedveld FC, Seymour AB. Correlation of polymorphic variation in the promoter region of the interleukin-1 beta gene with secretion of interleukin-1 beta protein. Arthritis Rheum. 2004 June;50:1976-83.
16. Higuchi T, Seki N, Kamizono S, Yamada A, Kimura A, Kato H, Itoh K. Polymorphism of the 5′-flanking region of the human tumor necrosis factor (TNF)-alpha gene in Japanese. Tissue Antigens. 1998 June;51:605-12.
17. Lv K, Chen R, Cai Q, Fang M, Sun S. Effects of a single nucleotide polymorphism on the expression of human tumor necrosis factor-alpha. Scand J Immunol. 2006 August;64:164-9.
18. Van Heel DA, Udalova IA, De Silva AP, McGovern DP, Kinouchi Y, Hull J, Lench NJ, Cardon LR, Carey AH, Jewell DP, Kwiatkowski D. Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF-kappaB transcription factors. Hum Mol Genet. 2002 May;16;11:1281-9.
19. Udalova IA, Richardson A, Denys A, Smith C, Ackerman H, Foxwell B, Kwiatkowski D. Functional consequences of a polymorphism affecting NF-κB p50-p50 binding to the TNF promoter region. Mol Cell Biol. 2000 December;20:9113-9.
20. Skoog T, van't Hooft FM, Kallin B, Jovinge S, Boquist S, Nilsson J, Eriksson P, Hamsten A. A common functional polymorphism (C - > A substitution at position -863) in the promoter region of the tumour necrosis factor-alpha (TNF-α) gene associated with reduced circulating levels of TNF-α. Hum Mol Genet. 1999 August;8:1443-9.
21. Nukui T, Day RD, Sims CS, Ness RB, Romkes M. Maternal/newborn GSTT1 null genotype contributes to risk of preterm, low birthweight infants. Pharmacogenetics. 2004 September;14:569-76.
22. Mitchell LE, Murray JC, O'Brien S, Christensen K. Evaluation of two putative susceptibility loci for oral clefts in the Danish population. Am J Epidemiol. 2001 May;15;153:1007-15.
23. Bathum L, Christiansen L, Tan Q, Vaupel J, Jeune B, Christensen K. No evidence for an association between extreme longevity and microsomal transfer protein polymorphisms in a longitudinal study of 1651 nonagenarians. Eur J Hum Genet. 2005 October;13:1154-8.