Forced expression of suppressor of cytokine signaling 3 in T cells protects the development of concanavalin A-induced hepatitis in mice

Clinical Immunology

Volumn 133, Issue 3, 2009, Pages 437-446

  Fushimi, Soichiro ^a   Ogino, Tetsuya ^a   Hara, Junko ^a   Takahata, Tomohiro ^a   Wakabayashi, Hiroshi ^a   Watanabe, Haruyuki ^a   Arashima, Yasuharu ^a   Kubo, Masato ^b   Matsukawa, Akihiro ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b RIKEN YOKOHAMA INSTITUTE   (Japan)

Author keywords

Concanavalin A; ; Fas; ; Hepatotoxicity; ; NKT cells; ; SOCS; ; T cells; ; Th1 cytokine; ; Transcription factor

Indexed keywords

CHEMOKINE; CONCANAVALIN A; CYTOKINE; FAS ANTIGEN; GRANZYME B; PERFORIN; STAT1 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; TRANSCRIPTION FACTOR T BET;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DISEASE COURSE; DRUG INHIBITION; FLOW CYTOMETRY; HEPATITIS; LIVER; LIVER CELL; LIVER INJURY; MALE; MOUSE; NATURAL KILLER T CELL; NONHUMAN; PRIORITY JOURNAL; PROTECTION; PROTEIN EXPRESSION; SURVIVAL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TH1 CELL;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CASPASES; CONCANAVALIN A; DNA FRAGMENTATION; GRANZYMES; HEPATITIS, ANIMAL; HISTOCYTOCHEMISTRY; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PERFORIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; SPECIFIC PATHOGEN-FREE ORGANISMS; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; SURVIVAL ANALYSIS; T-LYMPHOCYTES;

EID: 70350605493     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2009.08.015     Document Type: Article

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