Frequencies of HCV-specific effector CD4+ T cells by flow cytometry: Correlation with clinical disease stages

Hepatology

Volumn 35, Issue 1, 2002, Pages 190-198

  Rosen, Hugo R ^a   Miner, Camette ^a   Sasaki, Anna W ^a   Lewinsohn, David M ^a   Conrad, Andrew J ^b   Bakke, Antony ^a   Bouwer, H G Archie ^a,c   Hinrichs, David J ^a,c  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b National Genetics Institute   (United States)

^c PROVIDENCE PORTLAND MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; CD4 ANTIGEN; CYTOKINE; INTERLEUKIN 4; STAPHYLOCOCCUS ENTEROTOXIN;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION FUNCTION; CYTOKINE PRODUCTION; DISEASE COURSE; FEMALE; FLOW CYTOMETRY; HEPATITIS C; HUMAN; HUMAN CELL; MALE; PHENOTYPE; PRIORITY JOURNAL; T LYMPHOCYTE; VIRUS LOAD;

EID: 0036139684     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.2002.30293     Document Type: Article

References (38)

1. Global surveillance and control of HCV
2. Primer on hepatitis C for hospital epidemiologists
3. Replication of hepatitis C virus
4. Viral hepatitis following liver transplantation
5. T-lymphocyte response to hepatitis C virus in different clinical courses of infection
6. T- and B-cell responses to different hepatitis C virus antigens in patients with chronic hepatitis C virus infection and in healthy anti-hepatitis C virus-positive blood donors without viremia
7. Cellular immune responses persist and humoral responses decrease two decades after recovery from a single-source outbreak of hepatitis C
8. Different clinical behaviors of acute hepatitis C virus infection are associated with different vigor of the anti-viral cell-mediated immune response
9. Determination of antigen-specific memory/effector CD4+ T cell frequencies by flow cytometry: Evidence for a novel, antigen-specific homeostatic mechanism in HIV-associated immunodeficiency
10. A randomized trial of daily versus b.i.d. interferon induction followed by combination rebetron therapy for HCV genotype 1 infection
11. Morbidity and mortality in compensated cirrhosis type C: A retrospective followup study of 384 patients
12. Prediction of response during interferon alfa 2b therapy in chronic hepatitis C patients using viral and biochemical characteristics: A comparison
13. Typing of hepatitis C virus isolates and characterization of new subtypes using a line probe assay
14. Classification of hepatitis C into six major genotypes and a series of subtypes by phylogenetic analysis of the NS-5 region
15. Superantigens - Powerful modifiers of the immune system
16. Mycobacterium tuberculosis-reactive CD8+ T lymphocytes: The relative contribution of classical versus nonclassical HLA restriction
17. HIV-1-specific CD4+ T cells are detectable in most individuals with active HIV-1 infection, but decline with prolonged viral suppression
18. Pathogenesis, natural history, treatment, and prevention of hepatitis C
19. Human IL-10 is produced by both type 1 helper (Th1) and type 2 helper (Th2) cell clones and inhibits their antigen-specific proliferation and cytokine production
20. Virology of hepatitis C virus
21. Recurrence of hepatitis C virus after loss of virus-specific CD4+ T cell response in acute hepatitis C
22. Viral immune evasion due to persistence of activated T cells without effector function
23. Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremia
24. Hepatitis C virus specific immune responses in anti-HCV positive patients without hepatitis C viremia
25. Differential CD4+ and CD8+ T-cell responsiveness in hepatitis C virus infection
26. Detection of hepatitis C virus in paraffin-embedded liver biopsies of patients negative for viral RNA in serum
27. Possible mechanism involving T-lymphocyte responses to non-structural protein 3 in viral clearance in acute hepatitis C virus infection
28. The cellular immune responses induced in the followup of interferon-α treated patients with chronic hepatitis C may determine the therapy outcome
29. Analysis of a successful immune response against hepatitis C virus
30. Compartmentalization of T-lymphocytes to the site of the disease: Intrahepatic CD4+ T-cells specific for the protein NS4 of hepatitis C virus in patients with chronic hepatitis C
31. Immunopathogenesis of hepatitis C virus infection
32. Liver-derived hepatitis C virus (HCV)-specific CD4+ T cells recognize multiple HCV epitopes and produce interferon gamma
33. Strange brew: T cells in the liver
34. Dynamics of intra-hepatic lymphocytes in chronic hepatitis C: Enrichment for Vα24+ T cells and rapid elimination of effector cells by apoptosis
35. How is the liver unique?
36. Cell mediated immune response to the hepatitis C virus
37. Identification of HLA-A3 and B7-restricted CTL response to hepatitis C virus in patients with acute and chronic hepatitis C
38. Cytotoxic T lymphocyte response and viral load in hepatitis C virus infection