Hormonal Influences in the Expression of Systemic Lupus Erythematosus

Systemic Lupus Erythematosus: A Companion to Rheumatology

Volumn , Issue , 2007, Pages 87-94

  Rider, Virginia ^a   Li, Xiaolan ^b   Abdou, Nabih I ^c  

^a PITTSBURG STATE UNIVERSITY   (United States)

^b KUNMING MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 70350583530     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-323-04434-9.50014-2     Document Type: Chapter

References (81)

1. McGaha TL, Sorrentino B, Ravetch JV Restoration of tolerance in lupus by targeted inhibitory receptor expression. Science 2005, 307:590.
2. Bouneaud C, Kourilsky, Bousso P. Impact of negative selection on the T cell repertoire reactive to a self-peptide: A large fraction of T cell clones escapes clonal deletion. Immunity 2000, 13:829.
3. Marion TN, Krishnan MR, Steeves MA, et al. Affinity maturation and autoimmunity to DNA. Curr Dir Autoimm 2003, 6:123.
4. Jacobson DL, Gange SJ, Rose NR, et al. Epidemiology and estimated population burden of selected autoimmune disease in the United States. Clin Immunol Immunopath 1997, 84:223.
5. Whitacre CC, Reingold SC, O'Looney PA A gender gap in auto-immunity. Science 1999, 283:1277.
6. Lang TJ Estrogen as an immunomodulator. Clin Immunol 2004, 113:224.
7. Cutolo M, Sulli A, Capellino S, et al. Sex hormones influence on the immune system: Basic and clinical aspects in autoimmunity. Lupus 2004, 13:635.
8. Olsen NJ, Kovacs WJ Gonadal steroids and autoimmunity. Endocrinol Rev 1996, 17:369.
9. Wheetman AP, McGreagor AM, Smith BR, et al. Sex hormones enhance immunoglobulin synthesis by human peripheral blood lymphocytes. Immunol Lett 1981, 3:343.
10. Glaser TC, Watson A, Pardi R, et al. Effect of 17β estradiol on cytokine-induced endothelial cell adhesion molecule expression. J Clin Invest 1996, 98:36.
11. Paharkova-Vatchkova V, Maldonado R, Kovats S. Estrogen preferentially promotes the differentiation of CD11c+ CD11b (intermediate) dendritic cells from bone marrow precursors. J Immunol 2004, 172:1426.
12. Ito A, Bebo BF, Mefejuk A, et al. Estrogen treatment down-regulates TNF-a production and reduces the severity of experimental autoimmune encephalomyelitis in cytokine knockout mice. J Immunol 2001, 167:542.
13. Evans MJ, MacLaughlin S, Marvin D, et al. Estrogen decreases in vitro apoptosis of peripheral blood mononuclear cells from women with normal menstrual cycles and decreases TNF-a production in SLE but not in normal cultures. Clin Immunol Immunopathol 1997, 82:258.
14. Russell DH, Kibler R, Matrisian L, et al. Prolactin receptors on human T and B lymphocytes: Antagonism of prolactin binding by cyclosporine. J Immunol 1985, 134:3027.
15. Vera-Lastra O, Jara LJ, Espinoza LR Prolactin and autoimmunity. Autoimmun Rev 2002, 1:360.
16. Walker SE Prolactin in autoimmune disease. Principles of Gender-specific Medicine 2004, Elsevier Academic Press, San Diego. M.J. Legato (Ed.).
17. Elbourne KB, Keisler D, McMurray RW Differential effects of estrogen and prolactin on autoimmune disease in the NZB/NZW F1 mouse model of systemic lupus erythematosus. Lupus 1998, 7:420.
18. Peeva E, Michael D, Cleary J, et al. Prolactin modulates the naive B cell repertoire. J Clin Invest 2003, 111:275.
19. Verna-Lastra O, Mendez C, Jara LJ, et al. Correlation of prolactin serum concentrations with clinical activity and remission in patients with systemic lupus erythematosus: Effect of conventional treatment. J Rheumatol 2003, 30:2140.
20. Sanchez-Criado JE, Martin De Las Mulas J, Bellido C, et al. Biological role of pituitary estrogen receptors ERalpha and ERbeta on progesterone receptor expression and action and on gonadotropin and prolactin secretion in the rat. Neuroendocrinology 2004, 79:247.
21. Chen CC, Parker CR Adrenal androgens and the immune system. Semin Reprod Med 2004, 22:369.
22. Cameron DR, Braunstein GD The use of dehydroepiandrosterone therapy in clinical practice. Treat Endocrinol 2005, 4:95.
23. Robinzon B, Cutolo M. Should dehydroepinadrosterone replacement therapy be provided with glucocorticoids?. Rheumatology 1999, 38:488.
24. Chang DM, Lan JL, Lin HY, et al. Dehydroepiandrosterone treatment of women with mild-to-moderate systemic lupus erythematosus: A multicenter randomized, double-blind, placebo-controlled trial. Arthritis Rheum 2002, 46:2924.
25. Petri MA, Mease PJ, Merrill JT, et al. Effects of prasterone on disease activity and symptoms in women with active systemic lupus erythematosus. Arthritis Rheum 2004, 50:2858.
26. Nilsson S, Gustafsson J-A Estrogen receptor transcription and transactivation: Basic aspects of estrogen action. Breast Cancer Res 2000, 2:360.
27. Hewitt SC, Harrell JC, Korach KS Lessons in estrogen biology from knockout and transgenic animals. Annu Rev Physiol 2005, 67:285.
28. Hall JM, Couse JF, Korach KS The multifacted mechanisms of estrogen and estrogen receptor signaling. J Biol Chem 2001, 276:36869.
29. Grimaldi CM, Cleary J, Dagtas AS, et al. Estrogen alters thresholds for B cell apoptosis and activation. J Clin Invest 2002, 109:1625.
30. Rider V, Abdou NI Sexual dimorphism and the immune system. Principles of Gender-specific Medicine 2004, Elsevier Academic Press, San Diego. M.J. Legato (Ed.).
31. Grimaldi CM, Hill L, Xu X, et al. Hormonal modulation of B cell development and repertoire selection. Mol Immunol 2005, 42:811.
32. Czlonkowska A, Ciesielska A, Gromadzka G, et al. Estrogen and cytokines production-the possible cause of gender differences in neurological diseases. Curr Pharm Des 2005, 11:1017.
33. Gourdy P, Araujo LM, Zhu R, et al. Relevance of sexual dimorphism to regulatory T cells: Estrogen promotes IFNγ production by invariant natural killer T cells. Blood 2005, 105:2415.
34. Butterworth M, McClellan B, Allansmith M. Influence of sex in immunoglobulin levels. Nature 1967, 214:1224.
35. Kanda N, Tsuchida T, Tamaki K. Estrogen enhancement of anti-double stranded DNA antibody and immunoglobulin G production in peripheral blood mononuclear cells from patients with systemic lupus erythematosus. Arthritis Rheum 1999, 42:328.
36. Jenkins JK, Suwannaroj S, Elbourne KB, et al. 17β estradiol alters Jurkat lymphocyte cell cycling and induces apoptosis through suppression of Bcl-2 and cyclin A. Int Immunopharmacol 2001, 1:1897.
37. Miller L, Hunt JS Sex steroids, hormone and macrophage function. Life Sci 1995, 59:1.
38. McMurray RW, Suwannaroj, Ndebele K, et al. Differential effects of sex steroids on T and B cells: Modulation of cell cycle phase distribution apoptosis and Bcl-2 protein levels. Pathobio 2001, 69:44.
39. Murphy HS, Sun Q, Murphy BA, et al. Tissue-specific effect of estrogen on endothelial cell-dependent lymphocyte recruitment. Microvascular Res 2004, 68:273.
40. Polanczyk MJ, Carson BD, Subramanian S, et al. Estrogen drives expression of the CD4+ CD25+ regulatory T cell compartment. J Immuno 2004, 173:3227.
41. Bebo BF, Fyfe-Johnson A, Adlard K, et al. Low-dose estrogen therapy ameliorates experimental autoimmune encephalomyelitis in two different inbred mouse strains. J Immunol 2001, 166:2080.
42. Garidou L, Laffont S, Echninard VD, et al. Estrogen receptor a signaling in inflammatory leukocytes is dispensable for 17β-estradiol-mediated inhibition of experimental autoimmune encephalomyelitis. J Immunol 2004, 173:2435.
43. Koh KK Effects of estrogen on the vascular wall: Vasomotor function and inflammation. Cardiovascular Res 2002, 55:714.
44. Tsai MJ, O'Malley BW Molecular mechanisms of action of steroid/thyroid receptor superfamily members. Annu Rev Biochem 1994, 63:451.
45. Parker MG Structure and function of estrogen receptors. Vitam Horm 1995, 51:267.
46. Enmark E, Gustafsson JA Oestrogen receptors-an overview. J Int Med 1999, 246:133.
47. Qing X, Putterman C. Gene expression profiling in the study of the pathogenesis of autoimmune disease. Autoimmunity Rev 2004, 3:505.
48. Rider V, Foster RT, Evans M, et al. Gender differences in autoimmune diseases: Estrogen increases calcineurin expression in systemic lupus erythematosus. Clin Immunol Immunopathol 1998, 89:171.
49. Rider V, Jones S, Evans M, et al. Estrogen increases CD40 ligand expression in T cells from women with systemic lupus erythematosus. J Rheumatol 2001, 28:2644.
50. Sagawa A, Abdou NI Suppressor-cell dysfunction in systemic lupus erythematosus: Cells involved in and in vitro correction. J Clin Invest 1978, 62:789.
51. Abdou NI, Wall H, Lindsley HC, et al. The network theory in autoimmunity: In vitro suppression of serum anti-DNA antibody binding to DNA by anti-idiotypic antibody in systemic lupus erythematosus. J Clin Invest 1981, 67:1297.
52. Dayal AK, Kammer GM The T cell enigma in lupus. Arthritis Rheum 1996, 39:2333.
53. Kyttaris VC, Tsokos GC T lymphocytes in systemic lupus erythematosus: An update. Curr Opin Rheumatol 2004, 16:548.
54. Latham KA, Zamora A, Drought H, et al. Estradiol treatment redirects the isotype of the autoantibody response and prevents the development of autoimmune arthritis. J Immunol 2003, 171:5820.
55. Liu H, Loo KK, Palaszynski K, et al. Estrogen receptor a mediates estrogen's immune protection in autoimmune disease. J Immunol 2003, 171:6936.
56. Offner H. Neuroimmunoprotective effects of estrogen and derivatives in experimental autoimmune encephalomyelitis: Therapeutic implications for multiple sclerosis. J Neurosci Res 2004, 78:603.
57. Coffer PJ, Burgering BMT Forkhead-box transcription factors and their role in the immune system. Nature Rev Immunol 2004, 4:889.
58. Suenaga R, Rider V, Evans M, et al. Peripheral blood T cells and monocytes and B cell lines derived from patients with lupus express estrogen receptor transcripts similar to those of normal cells. J Rheumatol 1998, 25:1005.
59. Kassi EN, Vlachoyiannopoulos PG, Moutsopoulos HM, et al. Molecular analysis of estrogen receptor alpha and beta in lupus patients. Eur J Clin Invest 2001, 31:86.
60. Grimaldi CM, Michael DJ, Diamond B. Cutting edge: Expansion and activation of a population of autoreactive marginal zone B cells in a model of estrogen-induced lupus. J Immunol 2001, 167:1886.
61. McKenna NJ, Lanz RB, O'Malley BW Nuclear receptor coregulators: Cellular and molecular biology. Endocr Rev 1999, 20:321.
62. Grossman CJ, Roselle GA, Mendenhall CL Sex steroid regulation of autoimmunity. J Steroid Biochem Mol Biol 1991, 40:649.
63. Ansar AS, Penhale WJ, Talal N. Sex hormones, immune responses, and autoimmune diseases. Mechanisms of sex hormone action. Am J Pathol 1985, 121:531.
64. Rider V, Abdou NI Gender differences in autoimmunity: Molecular basis for estrogen effects in systemic lupus erythematosus. Int Immunopharmacol 2001, 1:1009.
65. Hall JM, McDonnell DP The estrogen receptor β-isoform (ERβ) of the human estrogen receptor modulates ERa transcriptional activity and is a key regulator of the cellular response to estrogen and antiestrogens. Endocrinology 1999, 140:5566.
66. Jones PS, Parrott E, White IN Activation of transcription by estrogen receptor alpha and beta is cell type-and promoter-dependent. J Biol Chem 1999, 274:32008.
67. Lahita RG, Bradlow HL, Kunkel HG, et al. Alteration of estrogen metabolism in systemic lupus erythematosus. Arthritis Rheum 1979, 22:1195.
68. Weidler C, Harle P, Schedel J, et al. Patients with rheumatoid arthritis and systemic lupus erythematosus have increased renal excretion of mitogenic estrogens in relation to endogenous antiestrogens. J Rheumatol 2004, 31:489.
69. McMurray RW Sex hormones in the pathogenesis of systemic lupus erythematosus. Front Biosci 2001, 6:E193.
70. Roubinian JR, Talal N, Greenspan JS, Goodman JR, Siiteri PK Effect of castration and sex hormone treatment on survival, anti-nucleic acid antibodies, and glomerulonephritis in NZB/NZW F1 mice. J Exp Med 1978, 147:1568.
71. Rider V, Jones SR, Evans M, et al. Molecular mechanisms involved in the estrogen-dependent regulation of calcineurin in systemic lupus erythematosus T cells. Clin Immunol 2000, 95:124.
72. Sherer Y, Gorstein A, Fritzler MJ, et al. Autoantibody explosion in systemic lupus erythematosus: More than100 different antibodies found in SLE patients. Semin Arthritis Rheum 2004, 34:501.
73. Suenaga R, Mitamura K, Evans MJ, et al. Binding affinity and quantity of estrogen receptor in peripheral blood monocytes of patients with systemic lupus erythematosus. Lupus 1996, 5:227.
74. Malter JS Posttransciptional regulation of mRNAs important in T cell function. Adv Immunol 1998, 68:1-49.
75. Ing N. Steroid hormones regulate gene expression posttranscriptionally by altering the stabilities of messenger RNAs. Biol Reprod 2005, 72:1290.
76. Rider V, Keltner S, Abdou NI Increased estrogen-dependent expression of calcineurin in female SLE T cells is regulated by multiple mechanisms. J Gend Specif Med 2003, 6:14.
77. Harrington WR, Sheng S, Barnett DH Activities of estrogen receptor alpha-and beta-selective ligands at diverse estrogen responsive gene sites mediating transactivation or transrepression. MCE 2003, 206:13.
78. Katzenellenbogen BS, Frasor J. Therapeutic targeting in the estrogen receptor hormonal pathway. Semin Oncol 2004, 31:28.
79. Rider V, Li X, Peterson G, et al. Differential expression of estrogen receptors in females with systemic lupus erythematosus. 2006 (in review).
80. Reid G, Hübner MR, Métivier R, et al. Cyclic, proteasome-mediated turnover of unliganded and liganded ERa on responsive promoters is an integral feature of estrogen signaling. Mol Cell 2003, 11:695.
81. Revankar CM, Cimino DF, Sklar LA, et al. A transmembrane intracellular estrogen receptor mediates rapid cell signaling. Science 2005, 307:1625.