Small interfering RNA-mediated suppression of dUTPase sensitizes cancer cell lines to thymidylate synthase inhibition

Molecular Pharmacology

Volumn 66, Issue 3, 2004, Pages 620-626

  Koehler, Sara E ^a   Ladner, Robert D ^a  

^a UMDNJ School of Osteopathic Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYURIDINE TRIPHOSPHATE PYROPHOSPHATASE; FLOXURIDINE; SMALL INTERFERING RNA; THYMIDYLATE SYNTHASE; URACIL;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL LEVEL; CELL STRAIN HT29; CELL STRAIN MCF 7; CELL SURVIVAL; CHEMOSENSITIVITY; CLONOGENIC ASSAY; COLON ADENOCARCINOMA; COLORECTAL CANCER; CONTROLLED STUDY; DNA STRAND BREAKAGE; DRUG CYTOTOXICITY; DRUG SENSITIZATION; DRUG TARGETING; ENZYME INHIBITION; HUMAN; HUMAN CELL; IC 50; NUCLEOTIDE METABOLISM; PRIORITY JOURNAL;

CELL LINE; DEOXYURACIL NUCLEOTIDES; DNA DAMAGE; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME INHIBITORS; HUMANS; PYROPHOSPHATASES; RNA, SMALL INTERFERING; THYMIDYLATE SYNTHASE; TUMOR CELLS, CULTURED;

EID: 4944241573     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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