-
1
-
-
0024467154
-
Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes
-
Kobayashi M, Fitz L, Ryan M, et al: Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes. J Exp Med 170:827-845, 1989
-
(1989)
J Exp Med
, vol.170
, pp. 827-845
-
-
Kobayashi, M.1
Fitz, L.2
Ryan, M.3
-
2
-
-
0025028960
-
Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells
-
Stern AS, Podlaski FJ, Hulmes JD, et al: Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells. Proc Natl Acad Sci U S A 87:6808-6812, 1990
-
(1990)
Proc Natl Acad Sci U S A
, vol.87
, pp. 6808-6812
-
-
Stern, A.S.1
Podlaski, F.J.2
Hulmes, J.D.3
-
3
-
-
0029014952
-
Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells
-
Macatonia SE, Hosken NA, Litton M, et al: Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells. J Immunol 154:5071-5079, 1995
-
(1995)
J Immunol
, vol.154
, pp. 5071-5079
-
-
Macatonia, S.E.1
Hosken, N.A.2
Litton, M.3
-
4
-
-
16044363695
-
IL-12-deficient mice are defective in IFN gamma production and type 1 cytokine responses
-
Magram J, Connaughton SE, Warrier RR, et al: IL-12-deficient mice are defective in IFN gamma production and type 1 cytokine responses. Immunity 4:471-481, 1996
-
(1996)
Immunity
, vol.4
, pp. 471-481
-
-
Magram, J.1
Connaughton, S.E.2
Warrier, R.R.3
-
5
-
-
0028265155
-
Interleukin 12 induces stable priming for interferon gamma (IFN-gamma) production during differentiation of human T helper (Th) cells and transient IFN-gamma production in established Th2 cell clones
-
Manetti R, Gerosa F, Giudizi MG, et al: Interleukin 12 induces stable priming for interferon gamma (IFN-gamma) production during differentiation of human T helper (Th) cells and transient IFN-gamma production in established Th2 cell clones. J Exp Med 179:1273-1283, 1994
-
(1994)
J Exp Med
, vol.179
, pp. 1273-1283
-
-
Manetti, R.1
Gerosa, F.2
Giudizi, M.G.3
-
6
-
-
0025875022
-
Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells
-
Wolf SF, Temple PA, Kobayashi M, et al: Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells. J Immunol 146:3074-3081, 1991
-
(1991)
J Immunol
, vol.146
, pp. 3074-3081
-
-
Wolf, S.F.1
Temple, P.A.2
Kobayashi, M.3
-
7
-
-
0027239503
-
Antitumor and antimetastatic activity of interleukin 12 against murine tumors
-
Brunda MJ, Luistro L, Warrier RR, et al: Antitumor and antimetastatic activity of interleukin 12 against murine tumors. J Exp Med 178:1223-1230, 1993
-
(1993)
J Exp Med
, vol.178
, pp. 1223-1230
-
-
Brunda, M.J.1
Luistro, L.2
Warrier, R.R.3
-
8
-
-
0036005890
-
Interleukin-12 in anti-tumor immunity and immunotherapy
-
Colombo MP, Trinchieri G: Interleukin-12 in anti-tumor immunity and immunotherapy. Cytokine Growth Factor Rev 13:155-168, 2002
-
(2002)
Cytokine Growth Factor Rev
, vol.13
, pp. 155-168
-
-
Colombo, M.P.1
Trinchieri, G.2
-
9
-
-
0034284460
-
The antitumor activity of IL-12: Mechanisms of innate immunity that are model and dose dependent
-
Smyth MJ, Taniguchi M, Street SE: The antitumor activity of IL-12: Mechanisms of innate immunity that are model and dose dependent. J Immunol 165:2665-2670, 2000
-
(2000)
J Immunol
, vol.165
, pp. 2665-2670
-
-
Smyth, M.J.1
Taniguchi, M.2
Street, S.E.3
-
10
-
-
0032526864
-
Interferon-inducible T cell alpha chemoattractant (ITAC): A novel non-ELR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CXCR3
-
Cole KE, Strick CA, Paradis TJ, et al: Interferon-inducible T cell alpha chemoattractant (ITAC): A novel non-ELR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CXCR3. J Exp Med 187:2009-2021, 1998
-
(1998)
J Exp Med
, vol.187
, pp. 2009-2021
-
-
Cole, K.E.1
Strick, C.A.2
Paradis, T.J.3
-
11
-
-
0031656897
-
Contribution of the CXC chemokines IP-10 and Mig to the antitumor effects of IL-12
-
Kanegane C, Sgadari C, Kanegane H, et al: Contribution of the CXC chemokines IP-10 and Mig to the antitumor effects of IL-12. J Leukoc Biol 64:384-392, 1998
-
(1998)
J Leukoc Biol
, vol.64
, pp. 384-392
-
-
Kanegane, C.1
Sgadari, C.2
Kanegane, H.3
-
12
-
-
0031001933
-
Mig, the monokine induced by interferon-gamma, promotes tumor necrosis in vivo
-
Sgadari C, Farber JM, Angiolillo AL, et al: Mig, the monokine induced by interferon-gamma, promotes tumor necrosis in vivo. Blood 89:2635-2643, 1997
-
(1997)
Blood
, vol.89
, pp. 2635-2643
-
-
Sgadari, C.1
Farber, J.M.2
Angiolillo, A.L.3
-
13
-
-
0028967287
-
Mouse interleukin-12 (IL-12) p40 homodimer: A potent IL-12 antagonist
-
Gillessen S, Carvajal D, Ling P, et al: Mouse interleukin-12 (IL-12) p40 homodimer: A potent IL-12 antagonist. Eur J Immunol 25:200-206, 1995
-
(1995)
Eur J Immunol
, vol.25
, pp. 200-206
-
-
Gillessen, S.1
Carvajal, D.2
Ling, P.3
-
14
-
-
0030445948
-
A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits
-
Presky DH, Yang H, Minetti LJ, et al: A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits. Proc Natl Acad Sci U S A 93:14002-14007, 1996
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 14002-14007
-
-
Presky, D.H.1
Yang, H.2
Minetti, L.J.3
-
15
-
-
36549030784
-
The inhibitory cytokine IL-35 contributes to regulatory T-cell function
-
Collison LW, Workman CJ, Kuo TT, et al: The inhibitory cytokine IL-35 contributes to regulatory T-cell function. Nature 450:566-569, 2007
-
(2007)
Nature
, vol.450
, pp. 566-569
-
-
Collison, L.W.1
Workman, C.J.2
Kuo, T.T.3
-
16
-
-
0345358584
-
The IL-12 family of heterodimeric cytokines: New players in the regulation of T cell responses
-
Trinchieri G, Pflanz S, Kastelein RA: The IL-12 family of heterodimeric cytokines: New players in the regulation of T cell responses. Immunity 19:641-644, 2003
-
(2003)
Immunity
, vol.19
, pp. 641-644
-
-
Trinchieri, G.1
Pflanz, S.2
Kastelein, R.A.3
-
17
-
-
0034672090
-
Expression and function of IL-12 and IL-18 receptors on human tonsillar B cells
-
Airoldi I, Gri G, Marshall JD, et al: Expression and function of IL-12 and IL-18 receptors on human tonsillar B cells. J Immunol 165:6880-6888, 2000
-
(2000)
J Immunol
, vol.165
, pp. 6880-6888
-
-
Airoldi, I.1
Gri, G.2
Marshall, J.D.3
-
18
-
-
0029116336
-
Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes
-
Bacon CM, Petricoin EF 3rd, Ortaldo JR, et al: Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes. Proc Natl Acad Sci U S A 92:7307-7311, 1995
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 7307-7311
-
-
Bacon, C.M.1
Petricoin 3rd, E.F.2
Ortaldo, J.R.3
-
19
-
-
0030469719
-
Activation of STAT4 by IL-12 and IFN-alpha: Evidence for the involvement of ligand-induced tyrosine and serine phosphorylation
-
Cho SS, Bacon CM, Sudarshan C, et al: Activation of STAT4 by IL-12 and IFN-alpha: Evidence for the involvement of ligand-induced tyrosine and serine phosphorylation. J Immunol 157:4781-4789, 1996
-
(1996)
J Immunol
, vol.157
, pp. 4781-4789
-
-
Cho, S.S.1
Bacon, C.M.2
Sudarshan, C.3
-
20
-
-
0032168336
-
IL-12 acts directly on DC to promote nuclear localization of NF-kappaB and primes DC for IL-12 production
-
Grohmann U, Belladonna ML, Bianchi R, et al: IL-12 acts directly on DC to promote nuclear localization of NF-kappaB and primes DC for IL-12 production. Immunity 9:315-323, 1998
-
(1998)
Immunity
, vol.9
, pp. 315-323
-
-
Grohmann, U.1
Belladonna, M.L.2
Bianchi, R.3
-
21
-
-
0029937270
-
Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice
-
Kaplan MH, Sun YL, Hoey T, et al: Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice. Nature 382:174-177, 1996
-
(1996)
Nature
, vol.382
, pp. 174-177
-
-
Kaplan, M.H.1
Sun, Y.L.2
Hoey, T.3
-
22
-
-
15844396183
-
Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
-
Thierfelder WE, van Deursen JM, Yamamoto K, et al: Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells. Nature 382:171-174, 1996
-
(1996)
Nature
, vol.382
, pp. 171-174
-
-
Thierfelder, W.E.1
van Deursen, J.M.2
Yamamoto, K.3
-
23
-
-
0034657259
-
Interleukin-2 enhances the response of natural killer cells to interleukin-12 through up-regulation of the interleukin-12 receptor and STAT4
-
Wang KS, Frank DA, Ritz J: Interleukin-2 enhances the response of natural killer cells to interleukin-12 through up-regulation of the interleukin-12 receptor and STAT4. Blood 95:3183-3190, 2000
-
(2000)
Blood
, vol.95
, pp. 3183-3190
-
-
Wang, K.S.1
Frank, D.A.2
Ritz, J.3
-
24
-
-
33646247193
-
Methylation of the IL-12Rbeta2 gene as novel tumor escape mechanism for pediatric B-acute lymphoblastic leukemia cells
-
Airoldi I, Cocco C, Di Carlo E, et al: Methylation of the IL-12Rbeta2 gene as novel tumor escape mechanism for pediatric B-acute lymphoblastic leukemia cells. Cancer Res 66:3978-3980, 2006
-
(2006)
Cancer Res
, vol.66
, pp. 3978-3980
-
-
Airoldi, I.1
Cocco, C.2
Di Carlo, E.3
-
25
-
-
50949131990
-
Constitutive expression of IL-12R beta 2 on human multiple myeloma cells delineates a novel therapeutic target
-
Airoldi I, Cocco C, Giuliani N, et al: Constitutive expression of IL-12R beta 2 on human multiple myeloma cells delineates a novel therapeutic target. Blood 112:750-759, 2008
-
(2008)
Blood
, vol.112
, pp. 750-759
-
-
Airoldi, I.1
Cocco, C.2
Giuliani, N.3
-
26
-
-
2942752374
-
The IL-12Rbeta2 gene functions as a tumor suppressor in human B cell malignancies
-
Airoldi I, Di Carlo E, Banelli B, et al: The IL-12Rbeta2 gene functions as a tumor suppressor in human B cell malignancies. J Clin Invest 113: 1651-1659, 2004
-
(2004)
J Clin Invest
, vol.113
, pp. 1651-1659
-
-
Airoldi, I.1
Di Carlo, E.2
Banelli, B.3
-
27
-
-
0028836185
-
Role of IL-12 in human B lymphocyte proliferation and differentiation
-
Jelinek DF, Braaten JK: Role of IL-12 in human B lymphocyte proliferation and differentiation. J Immunol 154:1606-1613, 1995
-
(1995)
J Immunol
, vol.154
, pp. 1606-1613
-
-
Jelinek, D.F.1
Braaten, J.K.2
-
28
-
-
0034541139
-
IL-12 receptor beta 2 (IL-12R beta 2)-deficient mice are defective in IL-12-mediated signaling despite the presence of high affinity IL-12 binding sites
-
Wu C, Wang X, Gadina M, et al: IL-12 receptor beta 2 (IL-12R beta 2)-deficient mice are defective in IL-12-mediated signaling despite the presence of high affinity IL-12 binding sites. J Immunol 165: 6221-6228, 2000
-
(2000)
J Immunol
, vol.165
, pp. 6221-6228
-
-
Wu, C.1
Wang, X.2
Gadina, M.3
-
29
-
-
28444443017
-
Lack of Il12rb2 signaling predisposes to spontaneous autoimmunity and malignancy
-
Airoldi I, Di Carlo E, Cocco C, et al: Lack of Il12rb2 signaling predisposes to spontaneous autoimmunity and malignancy. Blood 106:3846-3853, 2005
-
(2005)
Blood
, vol.106
, pp. 3846-3853
-
-
Airoldi, I.1
Di Carlo, E.2
Cocco, C.3
-
30
-
-
0036829305
-
Role of the bone marrow microenvironment in multiple myeloma
-
Roodman GD: Role of the bone marrow microenvironment in multiple myeloma. J Bone Miner Res 17:1921-1925, 2002
-
(2002)
J Bone Miner Res
, vol.17
, pp. 1921-1925
-
-
Roodman, G.D.1
-
31
-
-
0141765902
-
New insights into the pathophysiology of multiple myeloma
-
Seidl S, Kaufmann H, Drach J: New insights into the pathophysiology of multiple myeloma. Lancet Oncol 4:557-564, 2003
-
(2003)
Lancet Oncol
, vol.4
, pp. 557-564
-
-
Seidl, S.1
Kaufmann, H.2
Drach, J.3
-
32
-
-
36849017497
-
IL-6 involvement in epithelial cancers
-
Schafer ZT, Brugge JS: IL-6 involvement in epithelial cancers. J Clin Invest 117:3660-3663, 2007
-
(2007)
J Clin Invest
, vol.117
, pp. 3660-3663
-
-
Schafer, Z.T.1
Brugge, J.S.2
-
33
-
-
0037022341
-
IL-6 transgenic mouse model for extraosseous plasmacytoma
-
Kovalchuk AL, Kim JS, Park SS, et al: IL-6 transgenic mouse model for extraosseous plasmacytoma. Proc Natl Acad Sci U S A 99:1509-1514, 2002
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 1509-1514
-
-
Kovalchuk, A.L.1
Kim, J.S.2
Park, S.S.3
-
34
-
-
0033970534
-
The World Health Organization classification of neoplastic diseases of the haematopoietic and lymphoid tissues: Report of the Clinical Advisory Committee Meeting, Airlie House, Virginia, November 1997
-
Harris NL, Jaffe ES, Diebold J, et al: The World Health Organization classification of neoplastic diseases of the haematopoietic and lymphoid tissues: Report of the Clinical Advisory Committee Meeting, Airlie House, Virginia, November 1997. Histopathology 36:69-86, 2000
-
(2000)
Histopathology
, vol.36
, pp. 69-86
-
-
Harris, N.L.1
Jaffe, E.S.2
Diebold, J.3
-
35
-
-
0036212793
-
The interleukin-12 and interleukin-12 receptor system in normal and transformed human B lymphocytes
-
Airoldi I, Guglielmino R, Carra G, et al: The interleukin-12 and interleukin-12 receptor system in normal and transformed human B lymphocytes. Haematologica 87:434-442, 2002
-
(2002)
Haematologica
, vol.87
, pp. 434-442
-
-
Airoldi, I.1
Guglielmino, R.2
Carra, G.3
-
36
-
-
0028286005
-
DNA methylation and genomic imprinting
-
Razin A, Cedar H: DNA methylation and genomic imprinting. Cell 77:473-476, 1994
-
(1994)
Cell
, vol.77
, pp. 473-476
-
-
Razin, A.1
Cedar, H.2
-
37
-
-
0035839126
-
Epigenetic reprogramming in mammalian development
-
Reik W, Dean W, Walter J: Epigenetic reprogramming in mammalian development. Science 293:1089-1093, 2001
-
(2001)
Science
, vol.293
, pp. 1089-1093
-
-
Reik, W.1
Dean, W.2
Walter, J.3
-
38
-
-
0034744639
-
Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer
-
Baylin SB, Esteller M, Rountree MR, et al: Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer. Hum Mol Genet 10:687-692, 2001
-
(2001)
Hum Mol Genet
, vol.10
, pp. 687-692
-
-
Baylin, S.B.1
Esteller, M.2
Rountree, M.R.3
-
39
-
-
40849139208
-
Epigenetics in cancer
-
Esteller M: Epigenetics in cancer. N Engl J Med 358:1148-1159, 2008
-
(2008)
N Engl J Med
, vol.358
, pp. 1148-1159
-
-
Esteller, M.1
-
40
-
-
20144388146
-
Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer
-
Fraga MF, Ballestar E, Villar-Garea A, et al: Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer. Nat Genet 37:391-400, 2005
-
(2005)
Nat Genet
, vol.37
, pp. 391-400
-
-
Fraga, M.F.1
Ballestar, E.2
Villar-Garea, A.3
-
41
-
-
0345357773
-
Gene silencing in cancer in association with promoter hypermethylation
-
Herman JG, Baylin SB: Gene silencing in cancer in association with promoter hypermethylation. N Engl J Med 349:2042-2054, 2003
-
(2003)
N Engl J Med
, vol.349
, pp. 2042-2054
-
-
Herman, J.G.1
Baylin, S.B.2
-
43
-
-
43549099352
-
Interleukin-2, interleukin-12, and interferon-gamma levels and risk of young adult Hodgkin lymphoma
-
Cozen W, Gill PS, Salam MT, et al: Interleukin-2, interleukin-12, and interferon-gamma levels and risk of young adult Hodgkin lymphoma. Blood 111:3377-3382, 2008
-
(2008)
Blood
, vol.111
, pp. 3377-3382
-
-
Cozen, W.1
Gill, P.S.2
Salam, M.T.3
-
44
-
-
0013773866
-
5-Azacytidine, a new, highly effective cancerostatic
-
Sorm F, Piskala A, Cihak A, et al: 5-Azacytidine, a new, highly effective cancerostatic. Experientia 20:202-203, 1964
-
(1964)
Experientia
, vol.20
, pp. 202-203
-
-
Sorm, F.1
Piskala, A.2
Cihak, A.3
-
45
-
-
27144509196
-
DNA methyltransferase inhibitors and the development of epigenetic cancer therapies
-
Lyko F, Brown R: DNA methyltransferase inhibitors and the development of epigenetic cancer therapies. J Natl Cancer Inst 97:1498-1506, 2005
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 1498-1506
-
-
Lyko, F.1
Brown, R.2
-
46
-
-
0036965821
-
Zebularine: A novel DNA methylation inhibitor that forms a covalent complex with DNA methyltransferases
-
Zhou L, Cheng X, Connolly BA, et al: Zebularine: A novel DNA methylation inhibitor that forms a covalent complex with DNA methyltransferases. J Mol Biol 321:591-599, 2002
-
(2002)
J Mol Biol
, vol.321
, pp. 591-599
-
-
Zhou, L.1
Cheng, X.2
Connolly, B.A.3
-
47
-
-
33646071894
-
Decitabine improves patient outcomes in myelodysplastic syndromes: Results of a phase III randomized study
-
Kantarjian H, Issa JP, Rosenfeld CS, et al: Decitabine improves patient outcomes in myelodysplastic syndromes: Results of a phase III randomized study. Cancer 106:1794-1803, 2006
-
(2006)
Cancer
, vol.106
, pp. 1794-1803
-
-
Kantarjian, H.1
Issa, J.P.2
Rosenfeld, C.S.3
-
48
-
-
23844557794
-
Characterization of DNA demethylation effects induced by 5-Aza-2′-deoxycytidine in patients with myelodysplastic syndrome
-
Mund C, Hackanson B, Stresemann C, et al: Characterization of DNA demethylation effects induced by 5-Aza-2′-deoxycytidine in patients with myelodysplastic syndrome. Cancer Res 65:7086-7090, 2005
-
(2005)
Cancer Res
, vol.65
, pp. 7086-7090
-
-
Mund, C.1
Hackanson, B.2
Stresemann, C.3
-
49
-
-
34948845116
-
Safety and clinical activity of the combination of 5-azacytidine, valproic acid, and all-trans retinoic acid in acute myeloid leukemia and myelodysplastic syndrome
-
Soriano AO, Yang H, Faderl S, et al: Safety and clinical activity of the combination of 5-azacytidine, valproic acid, and all-trans retinoic acid in acute myeloid leukemia and myelodysplastic syndrome. Blood 110:2302-2308, 2007
-
(2007)
Blood
, vol.110
, pp. 2302-2308
-
-
Soriano, A.O.1
Yang, H.2
Faderl, S.3
-
50
-
-
0030887047
-
Phase I evaluation of intravenous recombinant human interleukin 12 in patients with advanced malignancies
-
Atkins MB, Robertson MJ, Gordon M, et al: Phase I evaluation of intravenous recombinant human interleukin 12 in patients with advanced malignancies. Clin Cancer Res 3:409-417, 1997
-
(1997)
Clin Cancer Res
, vol.3
, pp. 409-417
-
-
Atkins, M.B.1
Robertson, M.J.2
Gordon, M.3
-
51
-
-
13844262749
-
Intratumoral injection of DNA encoding human interleukin 12 into patients with metastatic melanoma: Clinical efficacy
-
Heinzerling L, Burg G, Dummer R, et al: Intratumoral injection of DNA encoding human interleukin 12 into patients with metastatic melanoma: Clinical efficacy. Hum Gene Ther 16:35-48, 2005
-
(2005)
Hum Gene Ther
, vol.16
, pp. 35-48
-
-
Heinzerling, L.1
Burg, G.2
Dummer, R.3
-
52
-
-
0035831628
-
Interleukin 12 gene therapy of cancer by peritumoral injection of transduced autologous fibroblasts: Outcome of a phase I study
-
Kang WK, Park C, Yoon HL, et al: Interleukin 12 gene therapy of cancer by peritumoral injection of transduced autologous fibroblasts: Outcome of a phase I study. Hum Gene Ther 12:671-684, 2001
-
(2001)
Hum Gene Ther
, vol.12
, pp. 671-684
-
-
Kang, W.K.1
Park, C.2
Yoon, H.L.3
-
53
-
-
0032900383
-
Immunological effects of interleukin 12 administered by bolus intravenous injection to patients with cancer
-
Robertson MJ, Cameron C, Atkins MB, et al: Immunological effects of interleukin 12 administered by bolus intravenous injection to patients with cancer. Clin Cancer Res 5:9-16, 1999
-
(1999)
Clin Cancer Res
, vol.5
, pp. 9-16
-
-
Robertson, M.J.1
Cameron, C.2
Atkins, M.B.3
-
54
-
-
33750611474
-
Review: Novel nonviral delivery approaches for interleukin-12 protein and gene systems-Curbing toxicity and enhancing adjuvant activity
-
Salem ML, Gillanders WE, Kadima AN, et al: Review: Novel nonviral delivery approaches for interleukin-12 protein and gene systems-Curbing toxicity and enhancing adjuvant activity. J Interferon Cytokine Res 26:593-608, 2006
-
(2006)
J Interferon Cytokine Res
, vol.26
, pp. 593-608
-
-
Salem, M.L.1
Gillanders, W.E.2
Kadima, A.N.3
-
55
-
-
10744233452
-
Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2′- deoxycytidine (decitabine) in hematopoietic malignancies
-
Issa JP, Garcia-Manero G, Giles FJ, et al: Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2′- deoxycytidine (decitabine) in hematopoietic malignancies. Blood 103:1635-1640, 2004
-
(2004)
Blood
, vol.103
, pp. 1635-1640
-
-
Issa, J.P.1
Garcia-Manero, G.2
Giles, F.J.3
-
56
-
-
17444452612
-
Low-dose 5-aza-2′- deoxycytidine, a DNA hypomethylating agent, for the treatment of high-risk myelodysplastic syndrome: A multicenter phase II study in elderly patients
-
Wijermans P, Lubbert M, Verhoef G, et al: Low-dose 5-aza-2′- deoxycytidine, a DNA hypomethylating agent, for the treatment of high-risk myelodysplastic syndrome: A multicenter phase II study in elderly patients. J Clin Oncol 18:956-962, 2000
-
(2000)
J Clin Oncol
, vol.18
, pp. 956-962
-
-
Wijermans, P.1
Lubbert, M.2
Verhoef, G.3
-
57
-
-
0026605457
-
IL-12 receptor: II. Distribution and regulation of receptor expression
-
Desai BB, Quinn PM, Wolitzky AG, et al: IL-12 receptor: II. Distribution and regulation of receptor expression. J Immunol 148:3125-3132, 1992
-
(1992)
J Immunol
, vol.148
, pp. 3125-3132
-
-
Desai, B.B.1
Quinn, P.M.2
Wolitzky, A.G.3
-
58
-
-
8044250881
-
Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells
-
Szabo SJ, Dighe AS, Gubler U, et al: Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells. J Exp Med 185:817-824, 1997
-
(1997)
J Exp Med
, vol.185
, pp. 817-824
-
-
Szabo, S.J.1
Dighe, A.S.2
Gubler, U.3
-
59
-
-
0035843169
-
Inactivation of the apoptosis effector Apaf-1 in malignant melanoma
-
Soengas MS, Capodieci P, Polsky D, et al: Inactivation of the apoptosis effector Apaf-1 in malignant melanoma. Nature 409:207-211, 2001
-
(2001)
Nature
, vol.409
, pp. 207-211
-
-
Soengas, M.S.1
Capodieci, P.2
Polsky, D.3
-
60
-
-
0036194917
-
Enhancement of the antitumor activity of interleukin-12 by targeted delivery to neovasculature
-
Halin C, Rondini S, Nilsson F, et al: Enhancement of the antitumor activity of interleukin-12 by targeted delivery to neovasculature. Nat Biotechnol 20:264-269, 2002
-
(2002)
Nat Biotechnol
, vol.20
, pp. 264-269
-
-
Halin, C.1
Rondini, S.2
Nilsson, F.3
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