A cis-proline in α-hemoglobin stabilizing protein directs the structural reorganization of α-hemoglobin

Journal of Biological Chemistry

Volumn 284, Issue 43, 2009, Pages 29462-29469

  Gell, David A ^a   Feng, Liang ^b   Zhou, Suiping ^c   Jeffrey, Philip D ^b   Bendak, Katerina ^a   Gow, Andrew ^d   Weiss, Mitchell J ^c   Shi, Yigong ^b   Mackay, Joel P ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b PRINCETON UNIVERSITY   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AXIAL POSITIONS; HEME POCKETS; NMR SPECTROSCOPY; REACTIVE OXYGEN SPECIES; REGULATORY PROTEIN; SIDE CHAINS; STRUCTURAL CHANGE; STRUCTURAL REORGANIZATION;

COORDINATION REACTIONS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OXYGEN; PORPHYRINS; X RAY CRYSTALLOGRAPHY;

HEMOGLOBIN;

ALPHA HEMOGLOBIN STABILIZING PROTEIN; BINDING PROTEIN; HEMOGLOBIN A; PROLINE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; GENETIC CONSERVATION; MUTAGENESIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STABILITY; PROTEIN STRUCTURE; X RAY CRYSTALLOGRAPHY;

BLOOD PROTEINS; CRYSTALLOGRAPHY, X-RAY; HEMOGLOBIN A; HUMANS; MOLECULAR CHAPERONES; MUTATION; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROLINE; PROTEIN STABILITY; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 70350365377     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.027045     Document Type: Article

References (69)

1. Kihm, A. J., Kong, Y., Hong, W., Russell, J. E., Rouda, S., Adachi, K., Simon, M. C., Blobel, G. A., and Weiss, M. J. (2002) Nature 417, 758-763
2. Feng, L., Zhou, S., Gu, L., Gell, D. A., Mackay, J. P., Weiss, M. J., Gow, A. J., and Shi, Y. (2005) Nature 435, 697-701
3. Gell, D., Kong, Y., Eaton, S. A., Weiss, M. J., and Mackay, J. P. (2002) J. Biol. Chem. 277, 40602-40609
4. Yu, X., Kong, Y., Dore, L. C., Abdulmalik, O., Katein, A. M., Zhou, S., Choi, J. K., Gell, D., Mackay, J. P., Gow, A. J., and Weiss, M. J. (2007) J. Clin. Invest. 117, 1856-1865
5. Feng, L., Gell, D. A., Zhou, S., Gu, L., Kong, Y., Li, J., Hu, M., Yan, N., Lee, C., Rich, A. M., Armstrong, R. S., Lay, P. A., Gow, A. J., Weiss, M. J., Mackay, J. P., and Shi, Y. (2004) Cell 119, 629-640
6. Kong, Y., Zhou, S., Kihm, A. J., Katein, A. M., Yu, X., Gell, D. A., Mackay, J. P., Adachi, K., Foster-Brown, L., Louden, C. S., Gow, A. J., and Weiss, M. J. (2004) J. Clin. Invest. 114, 1457-1466
7. Alayash, A. I. (2004) Nat. Rev. Drug Discov. 3, 152-159
8. Rifkind, J. M., Nagababu, E., Ramasamy, S., and Ravi, L. B. (2003) Redox Rep. 8, 234-237
9. Fessas, P. (1963) Blood 21, 21-32
10. Nathan, D. G., Stossel, T. B., Gunn, R. B., Zarkowsky, H. S., and Laforet, M. T. (1969) J. Clin. Invest. 48, 33-41
11. Finch, C. A., and Sturgeon, P. (1957) Blood 12, 64-73
12. Gabuzda, T. G., Nathan, D. G., and Gardner, F. H. (1963) J. Clin. Invest. 42, 1678-1688
13. Luzzatto, L., and Notaro, R. (2002) Nature 417, 703-705
14. de Sanctis, D., Pesce, A., Nardini, M., Bolognesi, M., Bocedi, A., and Ascenzi, P. (2004) IUBMB Life 56, 643-651
15. Halder, P., Trent, J. T., 3rd, and Hargrove, M. S. (2007) Proteins 66, 172-182
16. Dewilde, S., Kiger, L., Burmester, T., Hankeln, T., Baudin-Creuza, V., Aerts, T., Marden, M. C., Caubergs, R., and Moens, L. (2001) J. Biol. Chem. 276, 38949-38955
17. Lecomte, J. T., Scott, N. L., Vu, B. C., and Falzone, C. J. (2001) Biochemistry 40, 6541-6552
18. Levy, A., and Rifkind, J. M. (1985) Biochemistry 24, 6050-6054
19. Peterson-Kennedy, S. E., McGourty, J. L., Kalweit, J. A., and Hoffman, B. M. (1986) J. Am. Chem. Soc. 108, 1739-1746
20. Robinson, V. L., Smith, B. B., and Arnone, A. (2003) Biochemistry 42, 10113-10125
21. Rachmilewitz, E. A., Peisach, J., and Blumberg, W. E. (1971) J. Biol. Chem. 246, 3356-3366
22. Santiveri, C. M., Pérez-Cañadillas, J. M., Vadivelu, M. K., Allen, M. D., Rutherford, T. J., Watkins, N. A., and Bycroft, M. (2004) J. Biol. Chem. 279, 34963-34970
23. Fischer, G. (2000) Chem. Soc. Rev. 29, 119-127
24. Shaw, P. E. (2007) EMBO Rep. 8, 40-45
25. Lu, K. P., Finn, G., Lee, T. H., and Nicholson, L. K. (2007) Nat. Chem. Biol. 3, 619-629
26. Marley, J., Lu, M., and Bracken, C. (2001) J. Biomol. NMR 20, 71-75
27. Clore, G. M., and Gronenborn, A. M. (1994) Methods Enzymol. 239, 349-363
28. Montelione, G. T., Lyons, B. A., Emerson, S. D., and Tashiro, M. (1992) J. Am. Chem. Soc. 114, 10974-10975
29. Otwinowski, Z., and Minor, W. (1997) Methods Enzymol. 276, 307-326
30. Navaza, J. (2001) Acta Crystallogr. D Biol. Crystallogr. 57, 1367-1372
31. Jones, T. A., Zou, J. Y., Cowan, S. W., and Kjeldgaard, M. (1991) Acta Crystallogr. A 47, 110-119
32. Brünger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J. S., Kuszewski, J., Nilges, M., Pannu, N. S., Read, R. J., Rice, L. M., Simonson, T., and Warren, G. L. (1998) Acta Crystallogr. D. Biol. Crystallogr. 54, (Pt 5) 905-921
33. Grathwohl, C., and Wuthrich, K. (1981) Biopolymers 20, 2623-2633
34. Reimer, U., Scherer, G., Drewello, M., Kruber, S., Schutkowski, M., and Fischer, G. (1998) J. Mol. Biol. 279, 449-460
35. Jakob, R. P., and Schmid, F. X. (2008) J. Mol. Biol. 377, 1560-1575
36. Jakob, R. P., and Schmid, F. X. (2009) J. Mol. Biol. 387, 1017-1031
37. Schubert, M., Labudde, D., Oschkinat, H., and Schmieder, P. (2002) J. Biomol. NMR 24, 149-154
38. Riccio, A., Vitagliano, L., di Prisco, G., Zagari, A., and Mazzarella, L. (2002) Proc. Natl. Acad. Sci. U.S.A. 99, 9801-9806
39. Pesce, A., De Sanctis, D., Nardini, M., Dewilde, S., Moens, L., Hankeln, T., Burmester, T., Ascenzi, P., and Bolognesi, M. (2004) IUBMB Life 56, 657-664
40. Sadelain, M., Boulad, F., Galanello, R., Giardina, P., Locatelli, F., Maggio, A., Rivella, S., Riviere, I., and Tisdale, J. (2007) Hum. Gene. Ther. 18, 1-9
41. Hamdane, D., Vasseur-Godbillon, C., Baudin-Creuza, V., Hoa, G. H., and Marden, M. C. (2007) J. Biol. Chem. 282, 6398-6404
42. Zhou, S., Olson, J. S., Fabian, M., Weiss, M. J., and Gow, A. J. (2006) J. Biol. Chem. 281, 32611-32618
43. Brantley, R. E., Jr., Smerdon, S. J., Wilkinson, A. J., Singleton, E. W., and Olson, J. S. (1993) J. Biol. Chem. 268, 6995-7010
44. Balagopalakrishna, C., Manoharan, P. T., Abugo, O. O., and Rifkind, J. M. (1996) Biochemistry 35, 6393-6398
45. Dou, Y., Admiraal, S. J., Ikeda-Saito, M., Krzywda, S., Wilkinson, A. J., Li, T., Olson, J. S., Prince, R. C., Pickering, I. J., and George, G. N. (1995) J. Biol. Chem. 270, 15993-16001
46. Carrell, R. W. (1999) Science. 285, 1861
47. Mulcair, M. D., Schaeffer, P. M., Oakley, A. J., Cross, H. F., Neylon, C., Hill, T. M., and Dixon, N. E. (2006) Cell 125, 1309-1319
48. Fothergill, J. (1982) Nature 298, 705-706
49. Seidman, J. G., and Seidman, C. (2002) J. Clin. Invest. 109, 451-455
50. Wedemeyer, W. J., Welker, E., and Scheraga, H. A. (2002) Biochemistry 41, 14637-14644
51. Bauer, F., and Sticht, H. (2007) FEBS Lett. 581, 1555-1560
52. Russell, B. S., Zhong, L., Bigotti, M. G., Cutruzzolà, F., and Bren, K. L. (2003) J. Biol. Inorg. Chem. 8, 156-166
53. Shan, L., Tong, Y., Xie, T., Wang, M., and Wang, J. (2007) Biochemistry 46, 11504-11513
54. Krieger, F., Möglich, A., and Kiefhaber, T. (2005) J. Am Chem. Soc. 127, 3346-3352
55. Kabsch, W., and Sander, C. (1983) Biopolymers 22, 2577-2637
56. Pahlke, D., Freund, C., Leitner, D., and Labudde, D. (2005) BMC Struct. Biol. 5, 8
57. Nathaniel, C., Wallace, L. A., Burke, J., and Dirr, H. W. (2003) Biochem. J. 372, 241-246
58. Schultz, D. A., and Baldwin, R. L. (1992) Protein Sci. 1, 910-916
59. Schultz, D. A., Friedman, A. M., White, M. A., and Fox, R. O. (2005) Protein Sci. 14, 2862-2870
60. Kadokura, H., Nichols, L., 2nd, and Beckwith, J. (2005) J. Bacteriol. 187, 1519-1522
61. Kadokura, H., Tian, H., Zander, T., Bardwell, J. C., and Beckwith, J. (2004) Science 303, 534-537
62. McHarg, J., Kelly, S. M., Price, N. C., Cooper, A., and Littlechild, J. A. (1999) Eur. J. Biochem. 259, 939-945
63. Nam, G. H., Cha, S. S., Yun, Y. S., Oh, Y. H., Hong, B. H., Lee, H. S., and Choi, K. Y. (2003) Biochem. J. 375, 297-305
64. Smith, C. A., Cross, J. A., Bognar, A. L., and Sun, X. (2006) Acta Crystallogr. D. Biol. Crystallogr. 62, 548-558
65. Su, D., Berndt, C., Fomenko, D. E., Holmgren, A., and Gladyshev, V. N. (2007) Biochemistry 46, 6903-6910
66. Bacik, J. P., and Hazes, B. (2007) J. Mol. Biol. 365, 1545-1558
67. Noble, C. G., Hollingworth, D., Martin, S. R., Ennis-Adeniran, V., Smerdon, S. J., Kelly, G., Taylor, I. A., and Ramos, A. (2005) Nat. Struct. Mol. Biol. 12, 144-151
68. Ouyang, N., Gao, Y. G., Hu, H. Y., and Xia, Z. X. (2006) Proteins 65, 1021-1031
69. Paoli, M., Liddington, R., Tame, J., Wilkinson, A., and Dodson, G. (1996) J. Mol. Biol. 256, 775-792