Snapshots of DsbA in Action: Detection of Proteins in the Process of Oxidative Folding

Science

Volumn 303, Issue 5657, 2004, Pages 534-537

  Kadokura, Hiroshi ^a   Tian, Hongping ^a,c   Zander, Thomas ^b,d   Bardwell, James C A ^b   Beckwith, Jon ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^d NONE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL BONDS; MUTAGENESIS; OXIDATION; SULFIDE MINERALS;

MUTANTS;

PROTEINS;

DSBA PROTEIN; PROLINE; THIOREDOXIN;

PROTEIN;

ALKYLATION; ARTICLE; COVALENT BOND; DISULFIDE BOND; MUTATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FOLDING; PROTEIN PROCESSING;

AMINO ACID MOTIFS; BACTERIAL PROTEINS; DISULFIDES; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ESCHERICHIA COLI PROTEINS; ISOMERISM; MASS SPECTROMETRY; MEMBRANE PROTEINS; MOLECULAR WEIGHT; MUTATION; OXIDATION-REDUCTION; PLASMIDS; PROLINE; PROTEIN CONFORMATION; PROTEIN DISULFIDE-ISOMERASE; PROTEIN FOLDING; THIOREDOXIN; TRANSDUCTION, GENETIC;

EID: 1642556877     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1091724     Document Type: Article

References (32)

1. J. L. Martin, Structure 3, 245 (1995).
2. C. S. Sevier, C. A. Kaiser, Nature Rev. Mol. Cell Biol. 3, 836 (2002).
3. H. Kadokura, F. Katzen, J. Beckwith, Annu. Rev. Biochem. 72, 111 (2003).
4. J. C. Bardwell, K. McGovern, J. Beckwith, Cell 67, 581 (1991).
5. S. Kamitani, Y. Akiyama, K. Ito, EMBO J. 11, 57 (1992).
6. A. Zapun, J. C. Bardwell, T. E. Creighton, Biochemistry 32, 5083 (1993).
7. U. Grauschopf et al., Cell 83, 947 (1995).
8. S. Kishigami, Y. Akiyama, K. Ito, FEBS Lett. 364, 55 (1995).
9. J. C. Bardwell et al., Proc. Natl. Acad. Sci. U.S.A. 90, 1038 (1993).
10. T. Kobayashi et al., Proc. Natl. Acad. Sci. U.S.A. 94, 11857 (1997).
11. M. Bader, W. Muse, D. P. Ballou, C. Gassner, J. C. Bardwell, Cell 98, 217 (1999).
12. G. Jander, N. L. Martin, J. Beckwith, EMBO J. 13, 5121 (1994).
13. N. J. Darby, T. E. Creighton, Biochemistry 34, 3576 (1995).
14. F. Vinci, J. Couprie, P. Pucci, E. Quéméneur, M. Moutiez, Protein Sci. 11, 1600 (2002).
15. S. Kishigami, E. Kanaya, M. Kikuchi, K. Ito, J. Biol. Chem. 270, 17072 (1995).
16. H. Tian, D. Boyd, J. Beckwith, Proc. Natl. Acad. Sci. U.S.A. 97, 4730 (2000).
17. H. Kadokura, M. Bader, H. Tian, J. C. Bardwell, J. Beckwith, Proc. Natl. Acad. Sci. U.S.A. 97, 10884 (2000).
18. Materials and methods are available as supporting material on Science Online.
19. L. W. Guddat, J. C. Bardwell, T. Zander, J. L. Martin, Protein Sci. 6, 1148 (1997).
20. J. B. Charbonnier, P. Belin, M. Moutiez, E. A. Stura, E. Quéméneur, Protein Sci. 8, 96 (1999).
21. H. Kadokura et al., data not shown.
22. H. Kadokura, J. Beckwith, EMBO J. 21, 2354 (2002).
23. U. Grauschopf, A. Fritz, R. Glockshuber, EMBO J. 22, 3503 (2003).
24. R. Ortenberg, F. Katzen, J. Beckwith, unpublished results.
25. G. Richarme, Biochem. Biophys. Res. Commun. 252, 156 (1998).
26. J. Qin, G. M. Clore, W. P. Kennedy, J. Kuszewski, A. M. Gronenborn, Structure 4, 613 (1996).
27. A. Bateman et al., Nucleic Acids Res. 30, 276 (2002).
28. M. Molinari, A. Helenius, Nature 402, 90 (1999).
29. C. Frech, M. Wunderlich, R. Glockshuber, F. X. Schmid, EMBO J. 15, 392 (1996).
30. Y. Balmer et al., Proc. Natl. Acad. Sci. U.S.A. 100, 370 (2003).
31. K. Motohashi, A. Kondoh, M. T. Stumpp, T. Hisabori, Proc. Natl. Acad. Sci. U.S.A. 98, 11224 (2001).
32. We thank members of J.C.A.B. and J.B. laboratories for discussions. J.C.A.B. is a Pew Scholar. J.B. is an American Cancer Society Professor. Supported by NIH grants GM57039 (J.C.A.B.) and GM41883 (J.B.).