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Volumn 31, Issue 11, 2009, Pages 1651-1659

Biotechnology of flavours-the next generation

Author keywords

Aroma; Flavour; Fragrance; Genetic engineering; In situ product recovery; Volatiles

Indexed keywords

AGRICULTURAL SOURCES; AROMA; DE NOVO SYNTHESIS; ENVIRONMENTALLY-FRIENDLY; FLAVOUR; FLAVOUR PRECURSORS; FOOD INGREDIENTS; FUNCTIONALIZATIONS; GASPHASE; IMPROVED SUBSTRATE; IN SITU PRODUCT RECOVERY; IN-SITU; LARGER SUBSTRATES; MARKET SUCCESS; METABOLIC PATHWAYS; TWO-PHASE REACTIONS; VOLATILE ORGANIC CHEMICALS; VOLATILES;

EID: 70350289386     PISSN: 01415492     EISSN: 15736776     Source Type: Journal    
DOI: 10.1007/s10529-009-0083-5     Document Type: Review
Times cited : (184)

References (58)
  • 1
    • 34247609491 scopus 로고    scopus 로고
    • Vanillin production using metabolically engineered Escherichia coli under non-growing conditions
    • Barghini P, Di Gioia D, Fava F, Ruzzi M (2007) Vanillin production using metabolically engineered Escherichia coli under non-growing conditions. Microb Cell Fact 6:13.
    • (2007) Microb Cell Fact , vol.6 , pp. 13
    • Barghini, P.1    di Gioia, D.2    Fava, F.3    Ruzzi, M.4
  • 2
    • 50949084595 scopus 로고    scopus 로고
    • A ternary complex of hydroxycinnamoyl-CoA hydratase-lyase (HCHL) with acetyl-CoA and vanillin gives insights into substrate specificity and mechanism
    • Bennett JP, Bertin L, Moulton B, Fairlamb IJS, Brzozowski AM, Walton NJ, Grogan G (2008) A ternary complex of hydroxycinnamoyl-CoA hydratase-lyase (HCHL) with acetyl-CoA and vanillin gives insights into substrate specificity and mechanism. Biochem J 414:281-289.
    • (2008) Biochem J , vol.414 , pp. 281-289
    • Bennett, J.P.1    Bertin, L.2    Moulton, B.3    Fairlamb, I.J.S.4    Brzozowski, A.M.5    Walton, N.J.6    Grogan, G.7
  • 3
    • 33845270128 scopus 로고    scopus 로고
    • A kinetic study of lipase-catalyzed reversible kinetic resolution involving verification at miniplant-scale
    • Berendsen WR, Gendrot G, Freund A, Reuss M (2006) A kinetic study of lipase-catalyzed reversible kinetic resolution involving verification at miniplant-scale. Biotechnol Bioeng 95:883-892.
    • (2006) Biotechnol Bioeng , vol.95 , pp. 883-892
    • Berendsen, W.R.1    Gendrot, G.2    Freund, A.3    Reuss, M.4
  • 4
    • 33744520321 scopus 로고    scopus 로고
    • Cytochromes P 450 as versatile biocatalysts
    • Bernhardt R (2006) Cytochromes P 450 as versatile biocatalysts. J Biotechnol 124:128-145.
    • (2006) J Biotechnol , vol.124 , pp. 128-145
    • Bernhardt, R.1
  • 5
    • 56649120586 scopus 로고    scopus 로고
    • Characterization of monoterpene biotransformation in two pseudomonads
    • Bicas JL, Fontanille P, Pastore GM, Larroche C (2008) Characterization of monoterpene biotransformation in two pseudomonads. J Appl Microbiol 105:1991-2001.
    • (2008) J Appl Microbiol , vol.105 , pp. 1991-2001
    • Bicas, J.L.1    Fontanille, P.2    Pastore, G.M.3    Larroche, C.4
  • 6
    • 31144435087 scopus 로고    scopus 로고
    • A membrane bioreactor for the biotransformation of α-pinene oxide to isonovalal by Pseudomonas fluorescens NCIMB 11671
    • Boontawan A, Stuckey DC (2006) A membrane bioreactor for the biotransformation of α-pinene oxide to isonovalal by Pseudomonas fluorescens NCIMB 11671. Appl Microbiol Biotechnol 69:643-649.
    • (2006) Appl Microbiol Biotechnol , vol.69 , pp. 643-649
    • Boontawan, A.1    Stuckey, D.C.2
  • 8
    • 34548221362 scopus 로고    scopus 로고
    • Biocatalysis in non-conventional media-ionic liquids, supercritical fluids and the gas phase
    • Cantone S, Hanefeld U, Basso A (2007) Biocatalysis in non-conventional media-ionic liquids, supercritical fluids and the gas phase. Green Chem 9:954-971.
    • (2007) Green Chem , vol.9 , pp. 954-971
    • Cantone, S.1    Hanefeld, U.2    Basso, A.3
  • 11
    • 47349130224 scopus 로고    scopus 로고
    • A genomic search approach to identify esterases in Propionibacterium freudenreichii involved in the formation of flavour in Emmental cheese
    • Dherbecourt J, Falentin H, Canaan S, Thierry A (2008) A genomic search approach to identify esterases in Propionibacterium freudenreichii involved in the formation of flavour in Emmental cheese. Microb Cell Fact 7:.
    • (2008) Microb Cell Fact 7
    • Dherbecourt, J.1    Falentin, H.2    Canaan, S.3    Thierry, A.4
  • 12
    • 29244445773 scopus 로고    scopus 로고
    • Biotransformation of terpenic substrates by resting cells of Aspergillus niger and Pseudomonas putida isolates
    • Divyashree MS, George J, Agrawal R (2006) Biotransformation of terpenic substrates by resting cells of Aspergillus niger and Pseudomonas putida isolates. J Food Sci Technol 43:73-76.
    • (2006) J Food Sci Technol , vol.43 , pp. 73-76
    • Divyashree, M.S.1    George, J.2    Agrawal, R.3
  • 13
    • 33745963786 scopus 로고    scopus 로고
    • An aqueous-organic two-phase bioprocess for efficient production of the natural aroma chemicals 2-phenylethanol and 2-phenylethylacetate with yeast
    • Etschmann MMW, Schrader J (2006) An aqueous-organic two-phase bioprocess for efficient production of the natural aroma chemicals 2-phenylethanol and 2-phenylethylacetate with yeast. Appl Microbiol Biotechnol 71:440-443.
    • (2006) Appl Microbiol Biotechnol , vol.71 , pp. 440-443
    • Etschmann, M.M.W.1    Schrader, J.2
  • 15
    • 70350270040 scopus 로고
    • γ-Decalactone
    • WO 8301072 A1 19830331 Application WO82-US1323 19820927
    • Farbood MI, Willis BJ (1983) γ-Decalactone. PCT Int Appl, WO 8301072 A1 19830331 Application WO82-US1323 19820927.
    • (1983) PCT Int Appl
    • Farbood, M.I.1    Willis, B.J.2
  • 16
    • 48749105317 scopus 로고    scopus 로고
    • Lycopene accumulation affects the biosynthesis of some carotenoid-related volatiles independent of ethylene in tomato
    • Gao H, Zhu H, Shao Y, Chen A, Lu C, Zhu B, Luo Y (2008) Lycopene accumulation affects the biosynthesis of some carotenoid-related volatiles independent of ethylene in tomato. J Integr Plant Biol 50:991-996.
    • (2008) J Integr Plant Biol , vol.50 , pp. 991-996
    • Gao, H.1    Zhu, H.2    Shao, Y.3    Chen, A.4    Lu, C.5    Zhu, B.6    Luo, Y.7
  • 17
    • 33644851856 scopus 로고    scopus 로고
    • Biosynthesis of mono- and sesquiterpenes in strawberry fruits and foliage: 2H labeling studies
    • Hampel D, Mosandl A, Wuest M (2006) Biosynthesis of mono- and sesquiterpenes in strawberry fruits and foliage: 2H labeling studies. J Agric Food Chem 54:1473-1478.
    • (2006) J Agric Food Chem , vol.54 , pp. 1473-1478
    • Hampel, D.1    Mosandl, A.2    Wuest, M.3
  • 18
    • 42349106782 scopus 로고    scopus 로고
    • The Ehrlich pathway for fusel alcohol production: A century of research on Saccharomyces cerevisiae metabolism
    • Hazelwood LA, Daran JM, van Maris AJA, Pronk JT, Dickinson JR (2008) The Ehrlich pathway for fusel alcohol production: A century of research on Saccharomyces cerevisiae metabolism. Appl Environm Microbiol 74:2259-2266.
    • (2008) Appl Environm Microbiol , vol.74 , pp. 2259-2266
    • Hazelwood, L.A.1    Daran, J.M.2    van Maris, A.J.A.3    Pronk, J.T.4    Dickinson, J.R.5
  • 19
    • 58449120818 scopus 로고    scopus 로고
    • Characterization of the rice carotenoid cleavage dioxygenase 1 reveals a novel route for geranial biosynthesis
    • Ilg A, Beyer P, Al-Babili S (2009) Characterization of the rice carotenoid cleavage dioxygenase 1 reveals a novel route for geranial biosynthesis. FEBS J 276:736-747.
    • (2009) FEBS J , vol.276 , pp. 736-747
    • Ilg, A.1    Beyer, P.2    Al-Babili, S.3
  • 20
    • 37849039819 scopus 로고    scopus 로고
    • Cloning and characterization of two Lactobacillus casei genes encoding a cystathionine lyase
    • Irmler S, Raboud S, Beisert B, Rauhut D, Berthoud H (2008) Cloning and characterization of two Lactobacillus casei genes encoding a cystathionine lyase. Appl Environ Microbiol 74:99-106.
    • (2008) Appl Environ Microbiol , vol.74 , pp. 99-106
    • Irmler, S.1    Raboud, S.2    Beisert, B.3    Rauhut, D.4    Berthoud, H.5
  • 21
    • 48749084892 scopus 로고    scopus 로고
    • Isolation of cDNAs and functional characterisation of two multi-product terpene synthase enzymes from sandalwood, Santalum album L
    • Jones CG, Keeling CI, Ghisalberti EL, Barbour EL, Plummer JA, Bohlmann J (2008) Isolation of cDNAs and functional characterisation of two multi-product terpene synthase enzymes from sandalwood, Santalum album L. Arch Biochem Biophys 477:121-130.
    • (2008) Arch Biochem Biophys , vol.477 , pp. 121-130
    • Jones, C.G.1    Keeling, C.I.2    Ghisalberti, E.L.3    Barbour, E.L.4    Plummer, J.A.5    Bohlmann, J.6
  • 22
    • 45849137834 scopus 로고    scopus 로고
    • In situ recovery of the aroma compound perillene from stirred-tank cultured Pleurotus ostreatus using gas stripping and adsorption on polystyrene
    • Krings U, Berger RG (2008) In situ recovery of the aroma compound perillene from stirred-tank cultured Pleurotus ostreatus using gas stripping and adsorption on polystyrene. Biotechnol Lett 30:1347-1351.
    • (2008) Biotechnol Lett , vol.30 , pp. 1347-1351
    • Krings, U.1    Berger, R.G.2
  • 23
    • 0035936935 scopus 로고    scopus 로고
    • Phenyl propenoic side chain degradation of ferulic acid by Pycnoporus cinnabarinus-elucidation of metabolic pathways using [5-2H]-ferulic acid
    • Krings U, Pilawa S, Theobald C, Berger RG (2001) Phenyl propenoic side chain degradation of ferulic acid by Pycnoporus cinnabarinus-elucidation of metabolic pathways using [5-2H]-ferulic acid. J Biotechnol 85:305-314.
    • (2001) J Biotechnol , vol.85 , pp. 305-314
    • Krings, U.1    Pilawa, S.2    Theobald, C.3    Berger, R.G.4
  • 24
    • 47349085400 scopus 로고    scopus 로고
    • In vivo ESR spin trapping detection of carbon-centered α-farnesene radicals
    • Krings U, Andersen ML, Berger RG (2008a) In vivo ESR spin trapping detection of carbon-centered α-farnesene radicals. J Agric Food Chem 56:4333-4339.
    • (2008) J Agric Food Chem , vol.56 , pp. 4333-4339
    • Krings, U.1    Andersen, M.L.2    Berger, R.G.3
  • 25
    • 39149101459 scopus 로고    scopus 로고
    • A labeling study on the formation of perillene by submerged cultured oyster mushroom, Pleurotus ostreatus
    • Krings U, Hapetta D, Berger RG (2008b) A labeling study on the formation of perillene by submerged cultured oyster mushroom, Pleurotus ostreatus. Appl Microbiol Biotechnol 78:533-541.
    • (2008) Appl Microbiol Biotechnol , vol.78 , pp. 533-541
    • Krings, U.1    Hapetta, D.2    Berger, R.G.3
  • 26
    • 34548391489 scopus 로고    scopus 로고
    • Cloning and functional characterization of three terpene synthases from lavender (Lavandula angustifolia)
    • Landmann C, Fink B, Festner M, Dregus M, Engel K-H, Schwab W (2007) Cloning and functional characterization of three terpene synthases from lavender (Lavandula angustifolia). Arch Biochem Biophy 465:417-429.
    • (2007) Arch Biochem Biophy , vol.465 , pp. 417-429
    • Landmann, C.1    Fink, B.2    Festner, M.3    Dregus, M.4    Engel, K.-H.5    Schwab, W.6
  • 28
    • 33748881848 scopus 로고    scopus 로고
    • Production of food aroma compounds: Microbial and enzymatic methodologies
    • Longo MA, Sanroman MA (2006) Production of food aroma compounds: Microbial and enzymatic methodologies. Food Technol Biotechnol 44:335-353.
    • (2006) Food Technol Biotechnol , vol.44 , pp. 335-353
    • Longo, M.A.1    Sanroman, M.A.2
  • 29
    • 33947608924 scopus 로고    scopus 로고
    • Biotransformation of limonene: A review of the main metabolic pathways
    • Marostica J, Mario R, Pastore GM (2007) Biotransformation of limonene: A review of the main metabolic pathways. Quim Nova 30:382-387.
    • (2007) Quim Nova , vol.30 , pp. 382-387
    • Marostica, J.1    Mario, R.2    Pastore, G.M.3
  • 31
    • 34247184062 scopus 로고    scopus 로고
    • Pathway analysis of branched-chain ester biosynthesis in apple using deuterium labeling and enantioselective gas chromatography-mass spectrometry
    • Matich A, Rowan D (2007) Pathway analysis of branched-chain ester biosynthesis in apple using deuterium labeling and enantioselective gas chromatography-mass spectrometry. J Agric Food Chem 55:2727-2735.
    • (2007) J Agric Food Chem , vol.55 , pp. 2727-2735
    • Matich, A.1    Rowan, D.2
  • 32
    • 84989160703 scopus 로고    scopus 로고
    • Identification and flavor productivity of flavor producing wild yeasts isolated from various fruits
    • (in Japanese)
    • Matsuta Y, Ueki Atsuko, Ueki K (2009) Identification and flavor productivity of flavor producing wild yeasts isolated from various fruits. Nippon Jozo Kyokaishi 104: 57-74 (in Japanese).
    • (2009) Nippon Jozo Kyokaishi , vol.104 , pp. 57-74
    • Matsuta, Y.1    Atsuko, U.2    Ueki, K.3
  • 33
    • 62349127732 scopus 로고    scopus 로고
    • Carotenoid breakdown products the norisoprenoids in wine aroma
    • Mendes-Pinto MM (2009) Carotenoid breakdown products the norisoprenoids in wine aroma. Arch Biochem Biophys 483:236-245.
    • (2009) Arch Biochem Biophys , vol.483 , pp. 236-245
    • Mendes-Pinto, M.M.1
  • 34
    • 34547496584 scopus 로고    scopus 로고
    • An activity, stability and selectivity comparison of propioin synthesis by thiamine diphosphate-dependent enzymes in a solid/gas bioreactor
    • Mikolajek R, Spiess AC, Pohl M, Lamare S, Buechs J (2007) An activity, stability and selectivity comparison of propioin synthesis by thiamine diphosphate-dependent enzymes in a solid/gas bioreactor. ChemBioChem 8:1063-1070.
    • (2007) ChemBioChem , vol.8 , pp. 1063-1070
    • Mikolajek, R.1    Spiess, A.C.2    Pohl, M.3    Lamare, S.4    Buechs, J.5
  • 36
    • 55549097860 scopus 로고    scopus 로고
    • Enhanced bioproduction of carvone in a two-liquid-phase partitioning bioreactor with a highly hydrophobic biocatalyst
    • Morrish JLE, Brennan ET, Dry HC, Daugulis AJ (2008) Enhanced bioproduction of carvone in a two-liquid-phase partitioning bioreactor with a highly hydrophobic biocatalyst. Biotech Bioeng 101:768-775.
    • (2008) Biotech Bioeng , vol.101 , pp. 768-775
    • Morrish, J.L.E.1    Brennan, E.T.2    Dry, H.C.3    Daugulis, A.J.4
  • 37
    • 67649135036 scopus 로고    scopus 로고
    • Improved monoterpene biotransformation with Penicillium sp. by use of a closed gas loop bioreactor
    • doi:10.1007/s10295-009-0558-3
    • Pescheck M, Mirata MA, Brauer B, Krings U,Berger RG, Schrader J (2009) Improved monoterpene biotransformation with Penicillium sp. by use of a closed gas loop bioreactor J Ind Microbiol Biotechnol. doi:10.1007/s10295-009-0558-3.
    • (2009) J Ind Microbiol Biotechnol
    • Pescheck, M.1    Mirata, M.A.2    Brauer, B.3    Krings, U.4    Berger, R.G.5    Schrader, J.6
  • 38
    • 32444433426 scopus 로고    scopus 로고
    • Biosynthesis of plant volatiles: Nature's diversity and ingenuity
    • (Washington, DC)
    • Pichersky E, Noel JP, Dudareva N (2006) Biosynthesis of plant volatiles: Nature's diversity and ingenuity. Science (Washington, DC) 311:808-811.
    • (2006) Science , vol.311 , pp. 808-811
    • Pichersky, E.1    Noel, J.P.2    Dudareva, N.3
  • 40
    • 34547170651 scopus 로고    scopus 로고
    • Microbial production of C13-norisoprenoids and other aroma compounds via carotenoid cleavage
    • Rodriguez-Bustamante E, Sanchez S (2007) Microbial production of C13-norisoprenoids and other aroma compounds via carotenoid cleavage. Crit Revs Microbiol 33:211-230.
    • (2007) Crit Revs Microbiol , vol.33 , pp. 211-230
    • Rodriguez-Bustamante, E.1    Sanchez, S.2
  • 41
    • 41049106006 scopus 로고    scopus 로고
    • P450cam biocatalysis in surfactant-stabilized two-phase emulsions
    • Ryan JD, Clark DS (2008) P450cam biocatalysis in surfactant-stabilized two-phase emulsions. Biotechnol Bioeng 99:1311-1319.
    • (2008) Biotechnol Bioeng , vol.99 , pp. 1311-1319
    • Ryan, J.D.1    Clark, D.S.2
  • 42
    • 34248165882 scopus 로고    scopus 로고
    • Characterization of purified green bell pepper hydroperoxide lyase expressed by Yarrowia lipolytica: Radicals detection during catalysis
    • Santiago-Gomez MP, Vergely C, Policar C, Nicaud JM, Belin JM, Rochette L, Husson F (2007) Characterization of purified green bell pepper hydroperoxide lyase expressed by Yarrowia lipolytica: Radicals detection during catalysis. Enzyme Microb Technol 41:13-18.
    • (2007) Enzyme Microb Technol , vol.41 , pp. 13-18
    • Santiago-Gomez, M.P.1    Vergely, C.2    Policar, C.3    Nicaud, J.M.4    Belin, J.M.5    Rochette, L.6    Husson, F.7
  • 44
    • 38349103968 scopus 로고    scopus 로고
    • Improvement of P450BM-3 whole-cell biocatalysis by integrating heterologous cofactor regeneration combining glucose facilitator and dehydrogenase in E. coli
    • Schewe H, Kaup BA, Schrader J (2008) Improvement of P450BM-3 whole-cell biocatalysis by integrating heterologous cofactor regeneration combining glucose facilitator and dehydrogenase in E. coli. Appl Microbiol Biotechnol 78:55-65.
    • (2008) Appl Microbiol Biotechnol , vol.78 , pp. 55-65
    • Schewe, H.1    Kaup, B.A.2    Schrader, J.3
  • 47
    • 15044354250 scopus 로고    scopus 로고
    • Biocatalytic preparation of natural flavours and fragrances
    • Serra S, Fuganti C, Brenna E (2005) Biocatalytic preparation of natural flavours and fragrances. Trends Biotechnol 23:193-198.
    • (2005) Trends Biotechnol , vol.23 , pp. 193-198
    • Serra, S.1    Fuganti, C.2    Brenna, E.3
  • 48
    • 11844256914 scopus 로고    scopus 로고
    • Biotransformation of the sesquiterpene (+)-valencene by cytochrome P450cam and P450BM-3
    • Sowden RJ, Yasmin S, Rees NH, Bell SG, Wong LL (2005) Biotransformation of the sesquiterpene (+)-valencene by cytochrome P450cam and P450BM-3. Org Biomol Chem 3:57-64.
    • (2005) Org Biomol Chem , vol.3 , pp. 57-64
    • Sowden, R.J.1    Yasmin, S.2    Rees, N.H.3    Bell, S.G.4    Wong, L.L.5
  • 52
    • 54049118783 scopus 로고    scopus 로고
    • Stress response of Nidula niveo-tomentosa to UV-A light
    • Taupp DE, Nimtz M, Berger RG, Zorn H (2008) Stress response of Nidula niveo-tomentosa to UV-A light. Mycologia 100:529-538.
    • (2008) Mycologia , vol.100 , pp. 529-538
    • Taupp, D.E.1    Nimtz, M.2    Berger, R.G.3    Zorn, H.4
  • 53
    • 34249898122 scopus 로고    scopus 로고
    • Carotenoids: Properties, applications and biotransformation in flavor compounds
    • Uenojo M, Marostica Junior MR, Pastore GM (2007) Carotenoids: Properties, applications and biotransformation in flavor compounds. Quim Nova 30:616-622.
    • (2007) Quim Nova , vol.30 , pp. 616-622
    • Uenojo, M.1    Marostica Jr., M.R.2    Pastore, G.M.3
  • 54
    • 44249107290 scopus 로고    scopus 로고
    • Pathways that produce volatile sulphur compounds from methionine in Oenococcus oeni
    • Vallet A, Lucas P, Lonvaud-Funel A, de Revel G (2008) Pathways that produce volatile sulphur compounds from methionine in Oenococcus oeni. J Appl Microbiol 104:1833-1840.
    • (2008) J Appl Microbiol , vol.104 , pp. 1833-1840
    • Vallet, A.1    Lucas, P.2    Lonvaud-Funel, A.3    de Revel, G.4
  • 55
    • 45149133700 scopus 로고    scopus 로고
    • The carotenoid cleavage dioxygenase 1 enzyme has broad substrate specificity, cleaving multiple carotenoids at two different bond positions
    • Vogel JT, Tan BC, McCarty DR, Klee HJ (2008) The carotenoid cleavage dioxygenase 1 enzyme has broad substrate specificity, cleaving multiple carotenoids at two different bond positions. J Biol Chem 283:11364-11373.
    • (2008) J Biol Chem , vol.283 , pp. 11364-11373
    • Vogel, J.T.1    Tan, B.C.2    McCarty, D.R.3    Klee, H.J.4
  • 56
    • 36248952133 scopus 로고    scopus 로고
    • Microbial transformation of propenylbenzenes for natural flavor production
    • Xu P, Hua D, Ma C (2007) Microbial transformation of propenylbenzenes for natural flavor production. Trends Biotechnol 25:571-576.
    • (2007) Trends Biotechnol , vol.25 , pp. 571-576
    • Xu, P.1    Hua, D.2    Ma, C.3
  • 57
    • 0021763770 scopus 로고
    • Enzymic catalysis in organic media at 100°C
    • Zaks A, Klibanov AM (1984) Enzymic catalysis in organic media at 100°C. Science 224:1249-1251.
    • (1984) Science , vol.224 , pp. 1249-1251
    • Zaks, A.1    Klibanov, A.M.2
  • 58
    • 70350268101 scopus 로고    scopus 로고
    • Use of carotene-degrading oxidoreductase of Lepista irina in dishwashing or laundry detergents for treatment of stains
    • EP 1398381 A1 20040317
    • Zorn H, Langhoff S, Berger RG (2004) Use of carotene-degrading oxidoreductase of Lepista irina in dishwashing or laundry detergents for treatment of stains. Eur Pat Appl, EP 1398381 A1 20040317.
    • (2004) Eur Pat Appl
    • Zorn, H.1    Langhoff, S.2    Berger, R.G.3


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