Organophosphorus pesticides enhance the genotoxicity of benzo(a)pyrene by modulating its metabolism

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 671, Issue 1-2, 2009, Pages 84-92

  Hreljac, Irena ^a   Filipič, Metka ^a  

^a NATIONAL INSTITUTE OF BIOLOGY   (Slovenia)

Author keywords

Aldoketo reductase; Benzo(a)pyrene; Co genotoxicity; Micronucleus assay; Organophosphorous pesticides

Indexed keywords

AKR1C1 PROTEIN; AKR1C2 PROTEIN; BENZO[A]PYRENE; CYTOCHROME P450 1A; DIHYDRODIOL DEHYDROGENASE; ORGANOPHOSPHATE PESTICIDE; PARAOXON; PARAOXON METHYL; PARATHION METHYL; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HEPG2; COMET ASSAY; CONTROLLED STUDY; DNA STRAND BREAKAGE; ENZYME ACTIVITY; GENE EXPRESSION; GENOTOXICITY; HUMAN; HUMAN CELL; METABOLIC REGULATION; MICRONUCLEUS TEST; MUTATION; OXIDATIVE STRESS; PRIORITY JOURNAL;

BENZO(A)PYRENE; BIOTRANSFORMATION; CYTOCHROME P-450 CYP1A1; DRUG SYNERGISM; HEP G2 CELLS; HUMANS; MUTAGENICITY TESTS; MUTAGENS; ORGANOPHOSPHORUS COMPOUNDS; PESTICIDES; SALMONELLA TYPHIMURIUM;

BACTERIA (MICROORGANISMS);

EID: 70350277981     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2009.09.011     Document Type: Article

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