Proteomic study of neuron and astrocyte cultures from senescence- accelerated mouse SAMP8 reveals degenerative changes

Journal of Neurochemistry

Volumn 111, Issue 4, 2009, Pages 945-955

  Díez Vives, Cristina ^a   Gay, Marina ^b   García Matas, Silvia ^a   Comellas, Francesc ^c   Carrascal, Montserrat ^b   Abian, Joaquín ^b   Ortega Aznar, Arantxa ^d   Cristòfol, Rosa ^a   Sanfeliu, Coral ^a  

^a INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

^b CSIC   (Spain)

^c UNIVERSITAT POLITÈCNICA DE CATALUNYA   (Spain)

^d HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

Author keywords

Alzheimer's disease; Brain aging; Differential proteomics; Neuron and astrocyte cultures; Senescence accelerated prone mouse strain 8

Indexed keywords

ACTIN; ACYL COENZYME THIOESTERASE 1; ACYL COENZYME THIOESTERASE 2; CASPASE 3; CELL PROTEIN; CYTOSKELETON PROTEIN; ERLIN 2; FASCIN; HEAT SHOCK PROTEIN; PHOSPHOGLYCERATE DEHYDROGENASE; PHOSPHOGLYCERATE MUTASE 1; PHOSPHOSERINE AMINOTRANSFERASE; POLY(RC) BINDING PROTEIN 1; POLY(RC) BINDING PROTEIN 2; SERINE THREONINE PROTEIN PHOSPHATASE PP1 ALPHA; SUMO ACTIVATING ENZYME SUBUNIT 1; TUBULIN ALPHA 1A CHAIN; TUBULIN ALPHA 3 CHAIN; UNCLASSIFIED DRUG;

AGED; AGING; ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; ASTROCYTE; CELL CULTURE; COGNITIVE DEFECT; MOUSE; NERVE CELL; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEFECT; PROTEIN FUNCTION; PROTEOMICS; SENESCENCE ACCELERATED MOUSE; TIME OF FLIGHT MASS SPECTROMETRY;

AGING; ANIMALS; ASTROCYTES; CELLS, CULTURED; CEREBRAL CORTEX; COMPUTATIONAL BIOLOGY; DISEASE MODELS, ANIMAL; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; EMBRYO, MAMMALIAN; GENE EXPRESSION REGULATION; HEREDODEGENERATIVE DISORDERS, NERVOUS SYSTEM; METABOLIC NETWORKS AND PATHWAYS; MICE; MICE, INBRED STRAINS; NEURONS; PEPTIDE MAPPING; PROTEOMICS;

MUS;

EID: 70350135133     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2009.06374.x     Document Type: Article

References (46)

1. Butler D., Bendiske J., Michaelis M. L., Karanian D. A. Bahr B. A. (2007a) Microtubule stabilizing agent prevents protein accumulation-induced loss of synaptic markers. Eur. J. Pharmacol. 562, 20 27.
2. Butterfield D. A. Poon H. F. (2005) The senescence-accelerated prone mouse (SAMP8): a model of age-related cognitive decline with relevance to alterations of the gene expression and protein abnormalities in Alzheimer's disease. Exp. Gerontol. 40, 774 783.
3. Butterfield D. A., Howard B. J., Yatin S., Allen K. L. Carney J. M. (1997a) Free radical oxidation of brain proteins in accelerated senescence and its modulation by N-tert-butyl-alpha-phenylnitrone. Proc. Natl Acad. Sci. USA 94, 674 678.
4. Canudas A. M., Gutiérrez-Cuesta J., Rodríguez M. I., Acuña-Castroviejo D., Sureda F. X., Camins A. Pallàs M. (2005) Hyperphosphorylation of microtubule-associated protein tau in senescence-accelerated mouse (SAM). Mech. Ageing Dev. 126, 1300 1304.
5. Cao Danh H., Strolin Benedetti M. Dostert P. (1983) Age-related changes in aldehyde dehydrogenase activity of rat brain, liver, and heart. J. Neurochem. 41, 618 622.
6. Farr S. A., Poon H. F., Dogrukol-Ak D., Drake J., Banks W. A., Eyerman E., Butterfield D. A. Morley J. E. (2003) The antioxidants alpha-lipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice. J. Neurochem. 84, 1173 1183.
7. Flood J. F. Morley J. E. (1998) Learning and memory in the SAMP8 mouse. Neurosci. Biobehav. Rev. 22, 1 20.
8. Frandsen A. Schousboe A. (1990) Development of excitatory amino acid induced cytotoxicity in cultured neurons. Int. J. Dev. Neurosci. 8, 209 216.
9. Fujibayashi Y., Yamamoto S., Waki A., Konishi J. Yonekura Y. (1998) Increased mitochondrial DNA deletion in the brain of SAMP8, a mouse model for spontaneous oxidative stress brain. Neurosci. Lett. 254, 109 112.
10. Galvin J. E. Ginsberg S. D. (2003) Expression profiling in the aging brain: a perspective. Ageing Res. Rev. 4, 529 547.
11. García-Matas S., Gutiérrez-Cuesta J., Coto-Montes A., Rubio-Acero R., Díez-Vives C., Camins A., Pallàs M., Sanfeliu C. Cristòfol R. (2008) Dysfunction of astrocytes in the senescence- accelerated mice SAMP8 reduces their neuroprotective capacity. Aging Cell 7, 630 640.
12. Gulesserian T., Kim S. H., Fountoulakis M. Lubec G. (2002) Aberrant expression of centractin and capping proteins, integral constituents of the dynactin complex, in fetal Down syndrome brain. Biochem. Biophys. Res. Commun. 291, 62 67.
13. Hájek P., Chomyn A. Attardi G. (2007) Identification of a novel mitochondrial complex containing mitofusin 2 and stomatin-like protein 2. J. Biol. Chem. 282, 5670 5681.
14. Jouvenceau A., Hédou G., Potier B., Kollen M., Dutar P. Mansuy I. M. (2006) Partial inhibition of PP1 alters bidirectional synaptic plasticity in the hippocampus. Eur. J. Neurosci. 24, 564 572.
15. Kawamata T., Akiguchi I., Maeda K., Tanaka C., Higuchi K., Hosokawa M. Takeda T. (1998) Age-related changes in the brains of senescence-accelerated mice (SAM): association with glial and endothelial reactions. Microsc. Res. Tech. 43, 59 67.
16. Kimata Y., Higashio H. Kohno K. (2000) Impaired proteasome function rescues thermosensitivity of yeast cells lacking the coatomer subunit epsilon-COP. J. Biol. Chem. 275, 10655 10660.
17. Kumar V. B., Franko M. W., Farr S. A., Armbrecht J. Morley J. E. (2000) Identification of age-dependent changes in expression of senescence-accelerated mouse (SAMP8) hippocampal proteins by expression array analysis. Biochem. Biophys. Res. Commun. 272, 657 661.
18. Lü L., Li J., Yew D. T., Rudd J. A. Mak Y. T. (2008) Oxidative stress on the astrocytes in culture derived from a senescence accelerated mouse strain. Neurochem. Int. 52, 282 289.
19. Lü L., Mak Y. T., Fang M. Yew D. T. (2009) The difference in gliosis induced by β-amyloid and Tau treatments in astrocyte cultures derived from senescence accelerated and normal mouse strains. Biogerontology E-pub ahead of print, DOI : I., Zierz S. Möller H.-J. (2000) A selective defect of cytochrome c oxidase is present in brain of Alzheimer disease patients. Neurobiol. Aging 21, 455 462.
20. Mishra G. R., Suresh M., Kumaran K. et al. (2006) Human protein reference database - 2006 update. Nucleic Acids Res., 34, D411 D414.
21. Morley J. E., Farr S. A., Kumar V. B. Banks W. A. (2002) Alzheimer's disease through the eye of a mouse. Acceptance lecture for the 2001 Gayle A. Olson and Richard D. Olson prize. Peptides 23, 589 599.
22. Nabeshi H., Oikawa S., Inoue S., Nishino K. Kawanishi S. (2006) Proteomic analysis for protein carbonyl as an indicator of oxidative damage in senescence-accelerated mice. Free Radic. Res. 40, 1173 1181.
23. Ojaimi J., Masters C. L., McLean C., Opeskin K., McKelvie P. Byrne E. (1999) Irregular distribution of cytochrome c oxidase protein subunits in aging and Alzheimer's disease. Ann. Neurol. 46, 656 660.
24. Pallas M., Camins A., Smith M. A., Perry G., Lee H. Casadesus G. (2008) From aging to Alzheimer's disease: unveiling 'the switch' with the senescence-accelerated mouse model (SAMP8). J. Alzheimers Dis. 15, 615 624.
25. Pearce M. M. P., Wang Y., Kelley G. G. Wojcikiewicz R. J. H. (2007) SPFH2 mediates the endoplasmic reticulum-associated degradation of inositol 1,4,5-triphosphate receptors and other substrates in mammalian cells. J. Biol. Chem. 282, 20104 20115.
26. Picklo M. J., Olson S. J., Markesbery W. R. Montine T. J. (2001) Expression and activities of aldo-keto oxidoreductases in Alzheimer disease. J. Neuropathol. Exp. Neurol. 60, 686 695.
27. Poon H. F., Castegna A., Farr S. A., Thongboonkerd V., Lynn B. C., Banks W. A., Morley J. E., Klein J. B. Butterfield D. A. (2004) Quantitative proteomics analysis of specific protein expression and oxidative modification in aged senescence-accelerated-prone 8 mice brain. Neuroscience 126, 915 928.
28. Poon H. F., Vaishnav R. A., Butterfield D. A., Getchell M. L. Getchell T. V. (2005) Proteomic identification of differentially expressed proteins in the aging murine olfactory system and transcriptional analysis of the associated genes. J. Neurochem. 94, 380 392.
29. Poon H. F., Calabrese V., Calvani M. Butterfield A. (2006) Proteomic analyses of specific protein oxidation and protein expression in aged rat brain and its modulation by L-acetylcarnitine: insights into the mechanisms of action of this proposed therapeutic agent for CNS disorders associated with oxidative stress. Antioxid. Redox Signal. 8, 381 394.
30. Quero C., Colomé N., Prieto M. R., Carrascal M., Posada M., Gelpí E. Abian J. (2004) Determination of protein markers in human serum: analysis of protein expression in toxic oil syndrome. Proteomics 4, 303 315.
31. Ramirez-Boo M., Garrido J. J., Ogueta S., Calvete J. J., Gómez-Díaz C. Moreno A. (2006) Analysis of porcine peripheral blood mononuclear cells proteome by 2-DE and MS: analytical and biological variability in the protein expression level and protein identification. Proteomics 6, S215 S225.
32. Shevchenko A., Wilm M., Vorm O. Mann M. (1996) Mass spectrometric sequencing of proteins from silver-stained polyacrylamide gels. Anal. Chem. 68, 850 858.
33. Shiozaki A., Tsuji T., Kohno R., Kawamata J., Uemura K., Teraoka H. Shimohama S. (2004) Proteome analysis of brain proteins in Alzheimer's disease: subproteomics following sequentially extracted protein preparation. J. Alzheimers Dis. 6, 257 268.
34. Sowell R. A., Joshua B. O. Butterfield D. A. (2009) Proteomics in animal models of Alzheimer's and Parkinson's diseases. Ageing Res. Rev. 8, 1 17.
35. Sultana R., Boyd-Kimball D., Cai J., Pierce W. M., Klein J. B., Merchant M. Butterfield D. A. (2007) Proteomics analysis of the Alzheimer's disease hippocampal proteome. J. Alzheimers Dis. 11, 153 164.
36. Sureda F. X., Gutiérrez-Cuesta J., Romeu M., Mulero M., Canudas A. M., Camins A., Mallol J. Pallàs M. (2006) Changes in oxidative stress parameters and neurodegeneration markers in the brain of the senescence-accelerated mice SAMP8. Exp. Gerontol. 41, 360 367.
37. Takeda T. (1999) Senescence-accelerated mouse (SAM): a biogerontological resource in aging research. Neurobiol. Aging 20, 105 110.
38. Takeda T. (2009) Senescence-accelerated mouse (SAM) with special references to neurodegeneration models, SAMP8 and SAMP10. Neurochem. Res. 34, 639 659.
39. Takemura M., Nakamura S., Akiguchi I., Ueno M., Oka N., Ishikawa S., Shimada A., Kimura J. Takeda T. (1993) β/A4 protein-like immunoreactive granular structures in the brain of senescence-accelerated mouse. Am. J. Pathol. 142, 1887 1897.
40. Tomobe K. Nomura Y. (2009) Neurochemistry, neuropathology, and heredity in SAMP8: a mouse model of senescence. Neurochem. Res. 34, 660 669.
41. Tsugita A., Kawakami T., Uchida T., Sakai T., Kamo M., Matsui T., Watanabe Y., Morimasa T., Hosokawa K. Toda T. (2000) Proteoma analysis of mouse brain: two-dimensional electrophoresis profiles of tissue proteins during the course of aging. Electrophoresis 21, 1853 1871.
42. Verdier-Pinard P., Wang F., Martello L., Burd B., Orr G. A. Horwitz S. B. (2003) Analysis of tubulin isotypes and mutations from taxol-resistant cells by combined isoelectrofocusing and mass spectrometry. Biochemistry 42, 5349 5357.
43. Vernace V. A., Schmidt-Glenewinkel T. Figueiredo-Pereira M. E. (2007) Aging and regulated protein degradation: who has the upper hand? Aging Cell 6, 599 606.
44. Wang G. P., Khatoon S., Iqbal K. Grundke-Iqbal I. (1991) Brain ubiquitin is markedly elevated in Alzheimer disease. Brain Res. 566, 146 151.
45. Wang Q., Liu Y., Zou X., Wang Q., An M., Guan X., He J., Tong Y. Ji J. (2008) The hippocampal proteomic analysis of senescence-accelerated mouse: implications of Uchl3 and mitofilin in cognitive disorder and mitochondria dysfunction in SAMP8. Neurochem. Res. 32, 1776 1782.
46. Zellner M., Veitinger M. Umlauf E. (2009) The role of proteomics in dementia and Alzheimer's disease. Acta Neuropathol. 118, 181 195.