Irregular distribution of cytochrome c oxidase protein subunits in aging and Alzheimer's disease

Annals of Neurology

Volumn 46, Issue 4, 1999, Pages 656-660

  Ojaimi, Joseline ^a,b   Masters, Colin L ^b   McLean, Catriona ^b   Opeskin, Ken ^c   McKelvie, Penny ^a   Byrne, Edward ^a  

^a ST VINCENT S HOSPITAL   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c Vic Institute of Forensic Medicine   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME C OXIDASE;

AGING; ALZHEIMER DISEASE; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME LOCALIZATION; ENZYME SUBUNIT; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PURKINJE CELL; QUANTITATIVE DIAGNOSIS;

AGING; ALZHEIMER DISEASE; BRAIN; ELECTRON TRANSPORT COMPLEX IV; HUMANS; IMMUNOHISTOCHEMISTRY; MIDDLE AGED;

EID: 0032850682     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/1531-8249(199910)46:4<656::AID-ANA16>3.0.CO;2-Q     Document Type: Article

References (21)

1. Trounce I, Byrne E, Marzuki S. Decline in skeletal muscle mitochondrial respiratory chain function: possible factor in aging. Lancet 1989;1:1269
2. Yen TC, Chen YS, King KL, et al. Liver mitochondrial respiratory function decline with age. Biochem Biophys Res Commun 1989;165:994-1003
3. Kish SJ, Bergeron C, Raiput A, et al. Brain cytochrome oxidase in Alzheimer's disease. J Neurochem 1992;59:776-779
4. Parker WD, Jr, Parks J, Filley CM, Kleinschmidt-DeMasters BK. Electron transport chain defects in Alzheimer's disease brain. Neurology 1994;44:1090-1096
5. Mutisya EM, Bowling AC, Beal MF. Cortical cytochrome oxidase activity is reduced in Alzheimer's disease. J Neurochem 1994;44:1086-1090
6. Maurer I, Zierz S, Möller H-J, Jerusalem F. Cytochrome c oxidase in Alzheimer's disease. Neurology 1995;45:1423 (Letter)
7. Chagnon P, Robitaille Y, Gauvreau D. Brain mitochondrial DNA polymorphism and cytochrome oxidase activity in Alzheimer's disease. Alzheimer's Res 1996;2:237-242
8. Cooper JM, Wischik C, Schapira AHV. Mitochondrial function in Alzheimer's disease. Lancet 1993;341:969-970
9. Reichmann H, Flörke S, Heberstreit G, et al. Analyses of energy metabolism and mitochondrial genome in postmortem brain from patients with Alzheimer's disease. J Neurol 1993; 240:377-380
10. Byrne E, Dennett X, Trounce I, Henderson R. Partial cytochrome oxidase (aa3) deficiency in chronic progressive external ophthalmoplegia. Histochemical and biochemical studies. J Neurol Sci 1985;71:257-271
11. Müller-Höcker J, Johannes A, Droste M, et al. Fatal cardiomyopathy in Kearns-Sayre syndrome with deficiency of cytochrome c oxidase in cardiac and skeletal muscle. Virchows Arch B Cell Pathol Incl Mol Pathol 1986;52:353-367
12. Müller-Höcker J. Cytochrome c oxidase deficient cardiomyocytes in the human heart - an age-related phenomenon. Am J Pathol 1989;134:1167-1173
13. Mirra SS, Heyman A, McKeel D, et al. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology 1991;41:479-486
14. Boenisch T, Farmilo AJ, Stead RH. Handbook of immunochemical staining methods. Carpenteria, CA: Dako Corporation, 1989
15. Simonian NA, Hyman BT. Functional alterations in Alzheimer's disease: selective loss of mitochondrial-encoded cytochrome oxidase mRNA in the hippocampal formation. J Neuropathol Exp Neurol 1994;53:508-512
16. Chandrasekaran K, Hatanpää K, Rapoport SI, Brady DR. Decreased expression of nuclear and mitochondrial DNA-encoded genes of oxidative phosphorylation in association neocortex in Alzheimer's disease. Brain Res Mol Brain Res 1997;44:99-104
17. Bertoni-Freddari C, Fattoretti P, Casoli T, et al. Morphological plasticity of synaptic mitochondria during aging. Brain Res 1993;628:193-200
18. Hevner RF, Wong-Riley MTT. Neuronal expression of nuclear and mitochondrial genes for cytochrome oxidase (CO) subunits analyzed by in situ hybridization: comparison with CO activity and protein. J Neurosci 1991;11:1942-1958
19. Liu S, Wong-Riley M. Disproportionate regulation of nuclear- and mitochondrial-encoded cytochrome oxidase subunit proteins by functional activity in neurons. Neuroscience 1995;67:197-210
20. Vale RD, Schnapp BJ, Reese TS, Sheetz MP. Movement of organelles along filaments dissociated from the axoplasm of the squid giant axon. Cell 1985;40:449-454
21. Matsuyama SS, Jarvik LF. Hypothesis: microtubules, a key to Alzheimer's disease. Proc Natl Acad Sci USA 1989;86:8152-8156