Geldanamycin analog 17-DMAG inhibits iNOS and caspases in gamma-irradiated human T cells

Radiation Research

Volumn 172, Issue 3, 2009, Pages 321-330

  Kiang, Juliann G ^a   Smith, Joan T ^a   Agravante, Neil G ^a  

^a ARMED FORCES RADIOBIOLOGY RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

17 DEMETHOXY 17 (2 DIMETHYLAMINOETHYLAMINO)GELDANAMYCIN; APOPTOSOME; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE 3; CASPASE 9; CELL CYCLE PROTEIN 37; CYTOCHROME C; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; KRUPPEL LIKE FACTOR 6; MALONALDEHYDE; NITRIC OXIDE; 17-(DIMETHYLAMINOETHYLAMINO)-17-DEMETHOXYGELDANAMYCIN; BENZOQUINONE DERIVATIVE; CASPASE; GELDANAMYCIN; MACROCYCLIC LACTAM; NOS2A PROTEIN, HUMAN; RADIOPROTECTIVE AGENT;

APOPTOSIS; ARTICLE; CELL FUNCTION; CELL PROTECTION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; GAMMA RADIATION; HUMAN; HUMAN CELL; LIPID PEROXIDATION; NITRATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIATION DOSE; RADIATION EXPOSURE; RADIATION INJURY; T LYMPHOCYTE; DOSE RESPONSE; ENZYMOLOGY; LEUKEMIA CELL LINE; METABOLISM; PHYSIOLOGY; RADIATION RESPONSE;

BENZOQUINONES; CASPASES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOSE-RESPONSE RELATIONSHIP, RADIATION; GAMMA RAYS; HUMANS; JURKAT CELLS; LACTAMS, MACROCYCLIC; NITRIC OXIDE SYNTHASE TYPE II; RADIATION DOSAGE; RADIATION TOLERANCE; RADIATION-PROTECTIVE AGENTS; T-LYMPHOCYTES;

EID: 70349909701     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/RR1585.1     Document Type: Article

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