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Volumn 11, Issue 1 P.447-888, 2006, Pages 520-528

Role of the gut in the development of injury- and shock induced SIRS and MODS: The gut-lymph hypothesis, a review

Author keywords

Endothelial cell dysfunction; Gut lymph hypothesis; Lung injury; Mesenteric lymphatics; Review; Trauma; hemorrhagic shock

Indexed keywords


EID: 32944478013     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/1816     Document Type: Review
Times cited : (218)

References (48)
  • 1
    • 0000661570 scopus 로고
    • Transmural migration of intestinal bacteria
    • Schwinburg FB, A.M. Seligman & J. Fine: Transmural migration of intestinal bacteria. N. Engl J Med 242, 242-247 (1950)
    • (1950) N Engl J Med , vol.242 , pp. 242-247
    • Schwinburg, F.B.1    Seligman, A.M.2    Fine, J.3
  • 2
    • 0025677179 scopus 로고
    • Bacterial translocation of the gut flora
    • Deitch E.A.: Bacterial translocation of the gut flora. J Trauma 30:s184-s189 (1990)
    • (1990) J Trauma , vol.30
    • Deitch, E.A.1
  • 3
    • 0024075132 scopus 로고
    • Proposed mechanisms for the translocation of intestinal bacteria
    • Wells C.L., M.A. Maddaus & R.L. Simmons: Proposed mechanisms for the translocation of intestinal bacteria. Rev Inf Dis 10, 958-979 (1988)
    • (1988) Rev Inf Dis , vol.10 , pp. 958-979
    • Wells, C.L.1    Maddaus, M.A.2    Simmons, R.L.3
  • 4
    • 0025039336 scopus 로고
    • The process of microbial translocation
    • Alexander J.W., S.T. Boyce & G.F. Babcoc: The process of microbial translocation. Ann Surg 212, 496-512 (1990)
    • (1990) Ann Surg , vol.212 , pp. 496-512
    • Alexander, J.W.1    Boyce, S.T.2    Babcoc, G.F.3
  • 5
    • 0026744448 scopus 로고
    • Multiple organ failure: Pathophysiology and potential future therapy
    • Deitch E.A.: Multiple organ failure: Pathophysiology and potential future therapy. Ann Surg 216,117-134 (1992)
    • (1992) Ann Surg , vol.216 , pp. 117-134
    • Deitch, E.A.1
  • 7
    • 0031889919 scopus 로고    scopus 로고
    • The impact of antioxidant and splanchnic-directed therapy on persistent uncorrected gastric mucosal pH in the critically injured trauma patient
    • Barquist E, O. Kirton, J. Windsor, J. Hudson-Civetta & J. Civetta The impact of antioxidant and splanchnic-directed therapy on persistent uncorrected gastric mucosal pH in the critically injured trauma patient. J Trauma 44,355-60 (1998)
    • (1998) J Trauma , vol.44 , pp. 355-360
    • Barquist, E.1    Kirton, O.2    Windsor, J.3    Hudson-Civetta, J.4    Civetta, J.5
  • 8
    • 0032900817 scopus 로고    scopus 로고
    • Antioxidant therapy in the prevention of organ dysfunction syndrome and infectious complications after trauma: Early results of a prospective randomized study
    • Porter J.M., R.R. Ivatury, K. Azimuddin & R. Swami. Antioxidant therapy in the prevention of organ dysfunction syndrome and infectious complications after trauma: Early results of a prospective randomized study. Am Surg 65,478-483 (1999)
    • (1999) Am Surg , vol.65 , pp. 478-483
    • Porter, J.M.1    Ivatury, R.R.2    Azimuddin, K.3    Swami, R.4
  • 9
    • 0026008053 scopus 로고
    • Studies on the route, magnitude and time course of bacterial translocation in a model of systemic inflammation
    • Mainous M.R., P.Tso, S.D. Berg & E. A. Deitch: Studies on the route, magnitude and time course of bacterial translocation in a model of systemic inflammation. Arch Surg 126, 33-37 (1991)
    • (1991) Arch Surg , vol.126 , pp. 33-37
    • Mainous, M.R.1    Tso, P.2    Berg, S.D.3    Deitch, E.A.4
  • 10
    • 0027411590 scopus 로고
    • Trauma-hemorrhage and resuscitation in the mouse: Effects on cardiac output and organ blood flow
    • Wang P, F. Zheng, J. Burkhardt, & I. H. Chaudry: Trauma-hemorrhage and resuscitation in the mouse: effects on cardiac output and organ blood flow. Am J Physiol 264, H1166-H1173 (1993)
    • (1993) Am J Physiol , vol.264
    • Wang, P.1    Zheng, F.2    Burkhardt, J.3    Chaudry, I.H.4
  • 11
    • 0031606321 scopus 로고    scopus 로고
    • Animal models of sepsis and shock. A review and lessons learned
    • Deitch E.A.: Animal models of sepsis and shock. A review and lessons learned. Shock 9, 1-11 (1998)
    • (1998) Shock , vol.9 , pp. 1-11
    • Deitch, E.A.1
  • 12
    • 0023809141 scopus 로고
    • Hemorrhagic shock promotes the systemic translocation of bacteria from the gut
    • Baker T, E.A.Deitch, L. Ma & R. D. Berg: Hemorrhagic shock promotes the systemic translocation of bacteria from the gut. J Trauma 28, 896-906 (1988)
    • (1988) J Trauma , vol.28 , pp. 896-906
    • Baker, T.1    Deitch, E.A.2    Ma, L.3    Berg, R.D.4
  • 13
    • 0032471452 scopus 로고    scopus 로고
    • Gut-derived mesenteric lymph but not portal blood increases endothelial cell permeability and potentiates lung injury following hemorrhagic shock
    • Magnotti L.J., J. S. Upperman, D. Z. Xu, Q. Lu & E. A. Deitch: Gut-derived mesenteric lymph but not portal blood increases endothelial cell permeability and potentiates lung injury following hemorrhagic shock. Ann Surg 228, 518-527 (1998)
    • (1998) Ann Surg , vol.228 , pp. 518-527
    • Magnotti, L.J.1    Upperman, J.S.2    Xu, D.Z.3    Lu, Q.4    Deitch, E.A.5
  • 14
    • 0026695229 scopus 로고
    • Protective effects of prehaparinization on the microvasculature during and after hemorrhagic shock
    • Rana M.W., G. Singh, P. Wang, A. Ayala, M. Zhou & I. H. Chaudry: Protective effects of prehaparinization on the microvasculature during and after hemorrhagic shock. J Trauma 32, 420-426 (1992)
    • (1992) J Trauma , vol.32 , pp. 420-426
    • Rana, M.W.1    Singh, G.2    Wang, P.3    Ayala, A.4    Zhou, M.5    Chaudry, I.H.6
  • 15
    • 0032471452 scopus 로고    scopus 로고
    • Gut-derived mesenteric lymph but not portal blood increases endothelial cell permeability and potentiates lung injury following hemorrhagic shock
    • Magnotti L.J., J. S. Upperman, D. Z. Xu, Q. Lu & E. A. Deitch: Gut-derived mesenteric lymph but not portal blood increases endothelial cell permeability and potentiates lung injury following hemorrhagic shock. Ann Surg 228, 518-527 (1998)
    • (1998) Ann Surg , vol.228 , pp. 518-527
    • Magnotti, L.J.1    Upperman, J.S.2    Xu, D.Z.3    Lu, Q.4    Deitch, E.A.5
  • 16
    • 0035142246 scopus 로고    scopus 로고
    • A time course study of the protective effect of mesenteric lymph duct ligation on hemorrhagic shock-induced pulmonary injury and the toxic effects of lymph from shocked rats on endothelial cell monolayer permeability
    • Deitch E.A., C. A. Adams, Q. Lu & D. Z. Xu: A time course study of the protective effect of mesenteric lymph duct ligation on hemorrhagic shock-induced pulmonary injury and the toxic effects of lymph from shocked rats on endothelial cell monolayer permeability. Surgery 129, 39-47 (2001)
    • (2001) Surgery , vol.129 , pp. 39-47
    • Deitch, E.A.1    Adams, C.A.2    Lu, Q.3    Xu, D.Z.4
  • 17
    • 0034752549 scopus 로고    scopus 로고
    • Hemorrhagic shock induced up-regulation of P-selectin expression is mediated by factors in mesenteric lymph and blunted by mesenteric lymph duct interruption
    • Adams C.A., J. T. Sambol, D. Z. Xu, Q. Lu, D. N. Granger & E. A. Deitch: Hemorrhagic shock induced Up-regulation of P-selectin expression is mediated by factors in mesenteric lymph and blunted by mesenteric lymph duct interruption. J Trauma 51, 625-632 (2001)
    • (2001) J Trauma , vol.51 , pp. 625-632
    • Adams, C.A.1    Sambol, J.T.2    Xu, D.Z.3    Lu, Q.4    Granger, D.N.5    Deitch, E.A.6
  • 18
    • 0040669783 scopus 로고    scopus 로고
    • Trauma-hemorrhage-induced neutrophil priming is prevented by mesenteric lymph duct ligation
    • Adams C.A., C. J. Hauser, J. M. Adams, Z. Fekete, D. Z. Xu, J. T. Sambol & E. A. Deitch: Trauma-hemorrhage-induced neutrophil priming is prevented by mesenteric lymph duct ligation. Shock 18, 513-517 (2002)
    • (2002) Shock , vol.18 , pp. 513-517
    • Adams, C.A.1    Hauser, C.J.2    Adams, J.M.3    Fekete, Z.4    Xu, D.Z.5    Sambol, J.T.6    Deitch, E.A.7
  • 19
    • 0035489648 scopus 로고    scopus 로고
    • Mesenteric lymph from rats subjected to trauma-hemorrhagic shock are injurious to rat pulmonary microvascular endothelial cells as well as human umbilical vein endothelial cells
    • Deitch E.A., C. A. Adams, Q. Lu & D. Z. Xu: Mesenteric lymph from rats subjected to trauma-hemorrhagic shock are injurious to rat pulmonary microvascular endothelial cells as well as human umbilical vein endothelial cells. Shock 16, 290-293 (2001)
    • (2001) Shock , vol.16 , pp. 290-293
    • Deitch, E.A.1    Adams, C.A.2    Lu, Q.3    Xu, D.Z.4
  • 20
    • 0036596647 scopus 로고    scopus 로고
    • Trauma-hemorrhagic shock mesenteric lymph upregulates adhesion molecule expression and IL-6 production in human umbilical vein endothelial cells
    • Dayal S.D., G. Hasko, Q. Lu, D. Z. Xu, J. M. Caruso, J. T. Sambol & Deitch EA: Trauma-hemorrhagic shock mesenteric lymph upregulates adhesion molecule expression and IL-6 production in Human Umbilical vein Endothelial Cells. Shock 17,491-495 (2002)
    • (2002) Shock , vol.17 , pp. 491-495
    • Dayal, S.D.1    Hasko, G.2    Lu, Q.3    Xu, D.Z.4    Caruso, J.M.5    Sambol, J.T.6    Deitch, E.A.7
  • 21
    • 0035174035 scopus 로고    scopus 로고
    • Entry of gut lymph into the circulation primes rat neutrophil respiratory burst in hemorrhagic shock
    • Adams J.M., C. J. Hauser, C. A. Adams, D. Z. Xu, D. H. Livingston & E. A. Deitch: Entry of gut lymph into the circulation primes rat neutrophil respiratory burst in hemorrhagic shock. Crit Care Med 29, 2194-219 (2001)
    • (2001) Crit Care Med , vol.29 , pp. 2194-2219
    • Adams, J.M.1    Hauser, C.J.2    Adams, C.A.3    Xu, D.Z.4    Livingston, D.H.5    Deitch, E.A.6
  • 23
    • 0037289421 scopus 로고    scopus 로고
    • Mesenteric lymph duct ligation prevents shock-induced RBC deformability and shape changes
    • Zaets S. B., T. L. Berezina, J. Caruso, D. Z. Xu, E. A. Deitch & G. W. Machiedo: Mesenteric lymph duct ligation prevents shock-induced RBC deformability and shape changes. J Surg Res 109, 51-56 (2003)
    • (2003) J Surg Res , vol.109 , pp. 51-56
    • Zaets, S.B.1    Berezina, T.L.2    Caruso, J.3    Xu, D.Z.4    Deitch, E.A.5    Machiedo, G.W.6
  • 24
    • 7944219710 scopus 로고    scopus 로고
    • The role of lymph factors in lung injury, bone marrow suppression, and endothelial cell dysfunction in a primate model of trauma-hemorrhagic shock
    • Deitch E. A., R. Forsythe, D. Anjaria, D. H. Livingston, Q. Lu, D. Z. Xu & H. Redl: The role of lymph factors in lung injury, bone marrow suppression, and endothelial cell dysfunction in a primate model of trauma-hemorrhagic shock. Shock 22, 221-228 (2004)
    • (2004) Shock , vol.22 , pp. 221-228
    • Deitch, E.A.1    Forsythe, R.2    Anjaria, D.3    Livingston, D.H.4    Lu, Q.5    Xu, D.Z.6    Redl, H.7
  • 25
    • 0032755174 scopus 로고    scopus 로고
    • Gut-derived mesenteric lymph: A link between burn and lung injury
    • Magnotti L.J., D. Z. Xu, Q. Lu & E. A. Deitch: Gut-derived mesenteric lymph: A link between burn and lung injury. Arch Surg 134, 333-1341 (1999)
    • (1999) Arch Surg , vol.134 , pp. 333-1341
    • Magnotti, L.J.1    Xu, D.Z.2    Lu, Q.3    Deitch, E.A.4
  • 26
    • 0038722193 scopus 로고    scopus 로고
    • Burn-induced impairment of cardiac contractile function is due to gut-derived factors transported in mesenteric lymph
    • Sambol J. T., J. White, J. W. Horton & E. A. Deitch: Burn-induced impairment of cardiac contractile function is due to gut-derived factors transported in mesenteric lymph. Shock 18, 272-276 (2002)
    • (2002) Shock , vol.18 , pp. 272-276
    • Sambol, J.T.1    White, J.2    Horton, J.W.3    Deitch, E.A.4
  • 27
    • 0033562140 scopus 로고    scopus 로고
    • Posthemorrhagic shock mesenteric lymph primes circulating neutrophils and provokes lung injury
    • Zallen G., E. E. Moore, J. L. Johnson, D. Y. Tamura, D. J. Ciesla & C. C. Silliman: Posthemorrhagic shock mesenteric lymph primes circulating neutrophils and provokes lung injury. J Surg Res 83, 83-88 (1999)
    • (1999) J Surg Res , vol.83 , pp. 83-88
    • Zallen, G.1    Moore, E.E.2    Johnson, J.L.3    Tamura, D.Y.4    Ciesla, D.J.5    Silliman, C.C.6
  • 28
    • 9644290756 scopus 로고    scopus 로고
    • Systemic neutrophil priming by lipid mediators in post-shock mesenteric lymph exists across species
    • Sarin E. L., E. E. Moore, J. B. Moore, T. Masuno, J. L. Moore, A. Banerjee & C. C. Silliman: Systemic neutrophil priming by lipid mediators in post-shock mesenteric lymph exists across species. J. Trauma 57, 950-4 (2004)
    • (2004) J Trauma , vol.57 , pp. 950-954
    • Sarin, E.L.1    Moore, E.E.2    Moore, J.B.3    Masuno, T.4    Moore, J.L.5    Banerjee, A.6    Silliman, C.C.7
  • 29
    • 0035099039 scopus 로고    scopus 로고
    • Factors larger than 100 kD in post-hemorrhagic shock mesenteric lymph are toxic for endothelial cells
    • Adams C.A., D. Z. Xu, Q. Lu & E. A. Deitch: Factors larger than 100 kD in post-hemorrhagic shock mesenteric lymph are toxic for endothelial cells. Surgery 129, 351-362 (2001)
    • (2001) Surgery , vol.129 , pp. 351-362
    • Adams, C.A.1    Xu, D.Z.2    Lu, Q.3    Deitch, E.A.4
  • 30
    • 3042606212 scopus 로고    scopus 로고
    • A study of the biologic activity of trauma-hemorrhagic shock mesenteric lymph over time and the relative role of cytokines
    • Davidson M. T., E. A. Deitch, Q. Lu, A. Osband, E. Feketeova, Z. H. Nemeth, G. Hasko & D. Z. Xu: A study of the biologic activity of trauma-hemorrhagic shock mesenteric lymph over time and the relative role of cytokines. Surgery 136, 32-41 (2004)
    • (2004) Surgery , vol.136 , pp. 32-41
    • Davidson, M.T.1    Deitch, E.A.2    Lu, Q.3    Osband, A.4    Feketeova, E.5    Nemeth, Z.H.6    Hasko, G.7    Xu, D.Z.8
  • 31
    • 0034278233 scopus 로고    scopus 로고
    • The lipid fraction of post-hemorrhagic shock mesenteric lymph (PHSML) inhibits neutrophil apoptosis and enhances cytotoxic potential
    • Gonzalez R. J., E. E. Moore, W. L. Biffl, D. J. Ciesla & C. C. Silliman: The lipid fraction of post-hemorrhagic shock mesenteric lymph (PHSML) inhibits neutrophil apoptosis and enhances cytotoxic potential. Shock 14, 404-8 (2000)
    • (2000) Shock , vol.14 , pp. 404-408
    • Gonzalez, R.J.1    Moore, E.E.2    Biffl, W.L.3    Ciesla, D.J.4    Silliman, C.C.5
  • 32
    • 17644426966 scopus 로고    scopus 로고
    • Trauma-hemorrhagic shock mesenteric lymph from rat contains a modified form of albumin that is implicated in endothelial cell toxicity
    • Kaiser V. L., Z. C Sifri, G. S. Dikdan, T. Berezina, S. Zaets, Q. Lu, D. Z. Xu & E. A. Deitch: Trauma-hemorrhagic shock mesenteric lymph from rat contains a modified form of albumin that is implicated in endothelial cell toxicity. Shock 23, 417-425 (2005)
    • (2005) Shock , vol.23 , pp. 417-425
    • Kaiser, V.L.1    Sifri, Z.C.2    Dikdan, G.S.3    Berezina, T.4    Zaets, S.5    Lu, Q.6    Xu, D.Z.7    Deitch, E.A.8
  • 33
    • 2342544813 scopus 로고    scopus 로고
    • The role of oxidant-mediated pathways in the cytotoxicity of endothelial cells exposed to mesenteric lymph from rats subjected to trauma-hemorrhagic shock
    • Osband A.J., E. A. Deitch, Q. Lu, S. Zaets, S. Dayal, B. Lukose & D. Z. Xu: The role of oxidant-mediated pathways in the cytotoxicity of endothelial cells exposed to mesenteric lymph from rats subjected to trauma-hemorrhagic shock. Shock 20, 269-273 (2003)
    • (2003) Shock , vol.20 , pp. 269-273
    • Osband, A.J.1    Deitch, E.A.2    Lu, Q.3    Zaets, S.4    Dayal, S.5    Lukose, B.6    Xu, D.Z.7
  • 34
    • 3042651558 scopus 로고    scopus 로고
    • Trauma-hemorrhagic shock mesenteric lymph induces endothelial apoptosis that involves both Caspase-dependent and Caspase independent mechanisms
    • Davidson M. T., E. A. Deitch, Q. Lu, G. Hasko, B. Abungu, Z. H. Nemeth, S. B. Zaets, L. D. Gaspers, A. P. Thomas & D. Z. Xu: Trauma-hemorrhagic shock mesenteric lymph induces endothelial apoptosis that involves both Caspase-dependent and Caspase independent mechanisms. Ann Surg 240, 123-131 (2004)
    • (2004) Ann Surg , vol.240 , pp. 123-131
    • Davidson, M.T.1    Deitch, E.A.2    Lu, Q.3    Hasko, G.4    Abungu, B.5    Nemeth, Z.H.6    Zaets, S.B.7    Gaspers, L.D.8    Thomas, A.P.9    Xu, D.Z.10
  • 35
    • 0036597817 scopus 로고    scopus 로고
    • Hypertonic saline improves intestinal mucosa barrier function and lung injury after trauma-hemorrhagic shock
    • Shi H. P., E. A. Deitch, D. Z. Xu, Q. Lu & C. J. Hauser: Hypertonic saline improves intestinal mucosa barrier function and lung injury after trauma-hemorrhagic shock. Shock 17, 496-501 (2002)
    • (2002) Shock , vol.17 , pp. 496-501
    • Shi, H.P.1    Deitch, E.A.2    Xu, D.Z.3    Lu, Q.4    Hauser, C.J.5
  • 36
    • 0038113416 scopus 로고    scopus 로고
    • Hypertonic saline resuscitation limits neutrophil activation after trauma-hemorrhagic shock
    • Deitch E.A., H. P. Shi, E. Feketeova, C. J. Hauser & D. Z. Xu: Hypertonic saline resuscitation limits neutrophil activation after trauma-hemorrhagic shock. Shock 19, 328-333 (2003)
    • (2003) Shock , vol.19 , pp. 328-333
    • Deitch, E.A.1    Shi, H.P.2    Feketeova, E.3    Hauser, C.J.4    Xu, D.Z.5
  • 37
  • 39
  • 40
    • 0034652190 scopus 로고    scopus 로고
    • Generation of in vivo activating factors in the ischemic intestine by pancreatic enzymes
    • Mitsuoka H., E. B. Kistler & G. W. Schmid-Schonbein: Generation of in vivo activating factors in the ischemic intestine by pancreatic enzymes. Pro Natl Acad Sci USA 97, 1772-1777 (2000)
    • (2000) Pro Natl Acad Sci USA , vol.97 , pp. 1772-1777
    • Mitsuoka, H.1    Kistler, E.B.2    Schmid-Schonbein, G.W.3
  • 41
    • 1942511057 scopus 로고    scopus 로고
    • Serine proteases are involved in the pathogenesis of trauma-hemorrhagic shock-induced gut and lung injury
    • Deitch E. A., H. P. Shi, Q. Lu, E. Feketeova & D. Z. Xu: Serine proteases are involved in the pathogenesis of trauma-hemorrhagic shock-induced gut and lung injury. Shock 19, 452-456 (2003)
    • (2003) Shock , vol.19 , pp. 452-456
    • Deitch, E.A.1    Shi, H.P.2    Lu, Q.3    Feketeova, E.4    Xu, D.Z.5
  • 43
    • 32944469687 scopus 로고    scopus 로고
    • Immunological effects of sex hormones following hemorrhagic shock: Potential therapeutic applications
    • Angele M. K., M. Wichmann, S. Eisenmenger, F. W. Schildberg & I. H. Chaudry: Immunological effects of sex hormones following hemorrhagic shock: potential therapeutic applications. XX vs, YY 1, 39-47 (2003)
    • (2003) XX vs. YY , vol.1 , pp. 39-47
    • Angele, M.K.1    Wichmann, M.2    Eisenmenger, S.3    Schildberg, F.W.4    Chaudry, I.H.5
  • 44
    • 32944471632 scopus 로고    scopus 로고
    • Gut origin sepsis and MODS: The role of sex hormones in modulating intestinal and distant organ injury
    • Ananthakrishnan P. & E. A. Deitch: Gut origin sepsis and MODS: the role of sex hormones in modulating intestinal and distant organ injury. XX vs. XY 1, 108-117 (2003)
    • (2003) XX vs. XY , vol.1 , pp. 108-117
    • Ananthakrishnan, P.1    Deitch, E.A.2
  • 45
    • 0033778316 scopus 로고    scopus 로고
    • Acute lung injury after hemorrhagic shock is dependent on gut injury and gender
    • Adams C.A., L. J. Magnotti, D. Z. Xu, Q. Lu & E. A. Deitch: Acute lung injury after hemorrhagic shock is dependent on gut injury and gender. Am Surg 66, 905-913 (2000)
    • (2000) Am Surg , vol.66 , pp. 905-913
    • Adams, C.A.1    Magnotti, L.J.2    Xu, D.Z.3    Lu, Q.4    Deitch, E.A.5
  • 46
    • 0141522755 scopus 로고    scopus 로고
    • Gut injury and gut-induced lung injury after trauma hemorrhagic shock is gender and estrus cycle specific in the rat
    • Caruso J. M., E. A. Deitch, D. Z. Xu, Q. Lu & S. D. Dayal: Gut Injury and gut-induced lung injury after trauma hemorrhagic shock is gender and estrus cycle specific in the rat. J. Trauma 55,531-539 (2003)
    • (2003) J Trauma , vol.55 , pp. 531-539
    • Caruso, J.M.1    Deitch, E.A.2    Xu, D.Z.3    Lu, Q.4    Dayal, S.D.5
  • 47
    • 0028965103 scopus 로고
    • Elemental diet and IV-TPN-induced bacterial translocation is associated with loss of intestinal mucosal barrier function against bacteria
    • Deitch E.A., D. Z. Xu, M. B. Nahrun, D. C. Deitch, Q. Lu & A. A. Marino: Elemental diet and IV-TPN-induced bacterial translocation is associated with loss of intestinal mucosal barrier function against bacteria. Ann Surg 221, 299-307 (1995)
    • (1995) Ann Surg , vol.221 , pp. 299-307
    • Deitch, E.A.1    Xu, D.Z.2    Nahrun, M.B.3    Deitch, D.C.4    Lu, Q.5    Marino, A.A.6
  • 48
    • 11144283121 scopus 로고    scopus 로고
    • Sex hormones modulate distant organ injury in both a trauma/hemorrhagic shock model and a burn model
    • Ananthakrishnan P., D. B. Cohen, D. Z. Xu, Q. Lu, E. Feketeova & E. A. Deitch: Sex hormones modulate distant organ injury in both a trauma/hemorrhagic shock model and a burn model. Surgery 137, 56-65 (2005)
    • (2005) Surgery , vol.137 , pp. 56-65
    • Ananthakrishnan, P.1    Cohen, D.B.2    Xu, D.Z.3    Lu, Q.4    Feketeova, E.5    Deitch, E.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.