Gut injury and gut-induced lung injury after trauma hemorrhagic shock is gender and estrus cycle specific in the rat

Journal of Trauma

Volumn 55, Issue 3, 2003, Pages 531-539

  Caruso, Joseph M ^a   Deitch, Edwin A ^a   Xu, Da Zhong ^a   Lu, Qi ^a   Dayal, Sara D ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

Hemorrhagic shock; Intestinal dysfunction; Lung injury; Nitric oxide; Proestrus; Sepsis

Indexed keywords

MYELOPEROXIDASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ESTRUS CYCLE; FEMALE; HEMORRHAGIC SHOCK; INTESTINE INJURY; LAPAROTOMY; LUNG INJURY; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; PROESTRUS; RAT; SEPSIS; SEX DIFFERENCE;

ANIMALS; ESTROUS CYCLE; FEMALE; INTESTINES; LUNG; MALE; NITRIC OXIDE; PEROXIDASE; RATS; RATS, SPRAGUE-DAWLEY; RESUSCITATION; SEX FACTORS; SHOCK, HEMORRHAGIC; WOUNDS AND INJURIES;

EID: 0141522755     PISSN: 00225282     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.TA.0000025584.46870.95     Document Type: Article

References (44)

1. Deitch EA. Multiple organ failure: pathophysiology and potential future therapy. Ann Surg. 1992; 216: 117-134.
2. Moore FA, Sauaia A, Moore EE. Post injury multiple organ failure: a bimodal phenomenon. J Trauma. 1996; 40: 501-513.
3. Ivatory RR, Simon RJ, Islam S, Fueg A, Rohman M, Stahl WM. A prospective randomized study of end points of resuscitation after major trauma: global oxygen transport indices versus organ-specific gastric mucosal pH. J Am Coll Surg. 1996; 183: 145-154.
4. Rush BF, Sori AJ, Murphy TF, Smith S, Flanagan JJ, Machiedo GW. Endotoxemia and bacteremia hemorrhagic shock. Ann Surg. 1988; 207; 549-554.
5. Doig CJ, Sutherland LR, Sandham JD, Fick GH, Verhoef M, Meddings JB. Increased intestinal permeability is associated with the development of multiple organ dysfunction syndrome in critically ill ICU patients. Am J Respir Crit Care Med. 1998; 158: 444-451.
6. Magnotti LJ, Upperman JS, Xu DZ, Lu Q, Deitch EA. Gut-derived mesenteric lymph but not portal blood increases endothelial cell permeability and promotes lung injury after hemorrhagic shock. Ann Surg. 1998; 228: 518-527.
7. Magnotti LJ, Xu DZ, Lu Q, Deitch EA. Gut-derived mesenteric lymph: a link between burn and lung injury. Arch Surg. 1999; 134: 1333-1340.
8. Wichmann MW, Zellweger R, DeMaso CM, Ayala A, Chaudry IH. Enhanced immune responses in females as opposed to decreased responses in males following hemorrhagic shock and resuscitation. Cytokine. 1996; 8: 853-863.
9. Zellweger R, Wichmann MW, Ayala A, Stein S, DeMaso CM, Chaudry IH. Females in proestrus state maintain better splenic immune functions and tolerate sepsis better than males. Crit Care Med. 1997; 25: 106-110.
10. Jarrar D, Wang P, Coiffi WG, Bland KI, Chaudry IH. Mechanisms of the salutary effects of dehydroepiandrosterone after trauma-hemorrhage: direct or indirect effects on cardiac and hepatocellular functions? Arch Surg. 2000; 135: 416-423.
11. Adams CA, Magnotti LJ, Xu DZ, Lu Q, Deitch EA. Acute lung injury after hemorrhagic shock is dependent on gut injury and sex. Am Surg. 2000; 66: 905-913.
12. McGowan JE, Barnes MW, Finland M. Bacteremia at Boston city hospital: occurrence and mortality during 12 selected years (1935-1972), with special reference to hospital-acquired cases. J Infect Dis. 1975; 132: 316-335.
13. Eachempati SR, Lynn H, Barie PS. Gender-based differences in outcome in patients with sepsis. Arch Surg. 1999; 134: 1342-1347.
14. Schroder J, Kahlke V, Staubach KH, Zabel P, Stuber F. Gender differences in human sepsis. Arch Surg. 1998; 133: 1200-1205.
15. Angele MK, Schwacha MG, Ayala A, Chaudry IH. Effect of gender and sex hormones on immune responses following shock: a review article. Shock. 2000; 14: 81-90.
16. Mendelsohn ME, Karas RH. The protective effects of estrogen on the cardiovascular system. N Engl J Med. 1999; 340: 1801-1811.
17. Allan G, Bhattacherjee P, Brook CD, Read NG, Parke AJ. Myeloperoxidase activity as a quantitative marker of polymorphonuclear leukocyte activity into an experimental myocardial infarct: the effect of ibuprofen on infarct size and polymorphonuclear leukocyte accumulation. J Cardiovasc Pharmacol. 1985; 7: 1154-1160.
18. Baker HJ, Lindsey JR, Weisbroth SH. The Laboratory Rat, Volume 1, Biology and Diseases. New York: Academic Press; 1979: 54-156.
19. Wang P, Zheng F, Burkhardt J, Chaudry IH. Trauma-hemorrhage and resuscitation in the mouse: effects on cardiac output and organ flow. Am J Physiol. 1993; 264: H1166-H1173.
20. Deitch EA. Animal models of sepsis and shock: a review and lessons learned. Shock. 1998; 9: 1-11.
21. Baker T, Deitch EA, Ma L, Berg RD. Hemorrhagic shock promotes the systemic translocation of bacteria from the gut. J Trauma. 1988; 28: 896-906.
22. Rana MW, Singh G, Wang P, Ayala A, Zhou M, Chaudry IH. Protective effects of preheparinization on the microvasculature during and after hemorrhagic shock. Ann Surg. 1998; 228: 518-527.
23. Mishima S, Xu DZ, Lu Q, Deitch EA. Bacterial translocation is inhibited in inducible nitric oxide synthase knockout mice after endotoxin challenge but not in a model of bacterial overgrowth. Arch Surg. 1997; 132: 1190-1195.
24. Szabo C. Alteration in nitric oxide production in various forms of circulatory shock. New Horiz. 1995; 3: 2-32.
25. Salzmann AL. Nitric oxide in the gut. New Horiz. 1995; 3: 33-45.
26. Bone RC. Toward an epidemiology and natural history of SIRS. JAMA. 1992; 268: 3452-3455.
27. Offner PJ, Moore EE, Biffl WL. Male gender is a risk factor for major infections after surgery. Arch Surg. 1999; 134: 935-940.
28. Deitch EA, Adams CA, Lu Q, Xu DZ. A time course study of the protective effect of mesenteric lymph duct ligation on hemorrhagic shock-induced pulmonary injury and the toxic effects of lymph from shocked rats on the endothelial cell monolayer permeability. Surgery. 2001; 129: 39-47.
29. Dayal SD, Haskó G, Lu Q, et al. Trauma/hemorrhagic shock mesenteric lymph upregulates adhesion molecule expression and IL-6 production in human umbilical vein endothelial cells. Shock. In press.
30. Upperman JS, Deitch EA, Guo W, Lu Q, Xu DZ. Post hemorrhagic shock mesenteric lymph is cytotoxic to endothelial cells and activates neutrophils. Shock. 1998; 10: 407-414.
31. Altura BM. Sex and estrogens in protection against circulatory stress reactions. Am J Physiol. 1976; 231: 842-847.
32. Slimmer LM, Blair ML. Female reproductive cycle influences plasma volume and protein restitution after hemorrhage in the conscious rat. Am J Physiol. 1996; 119: R626-R633.
33. Kuebler JF, Doraid J, Toth B, et al. Estradiol administration improves splanchnic perfusion following trauma-hemorrhage and sepsis. Arch Surg. 2002; 137: 74-79.
34. Zhang Y, Davidge ST. Effect of estrogen replacement on vasoconstrictor responses in rat mesenteric arteries. Hypertension. 1999; 34: 1117-1122.
35. Ferrer M, Meyer M, Osol G. Estrogen replacement increases adrenergic-mediated relaxation of rat mesenteric arteries. J Vasc Res. 1996; 33: 124-131.
36. Altura BM. Sex and estrogens and responsiveness of terminal arterioles to neurohypophyseal hormones and catecholamines. J Pharmacol Exp Ther. 1975; 193: 403-412.
37. Crofton JT, Share L. Sexual dimorphism in vasopressin and cardiovascular response to hemorrhage in the rat. Circ Res. 1990; 66: 1345-1353.
38. St-Louis J, Parent A, Lariviere R, Schiffrin EL. Vasopressin responses and receptors in the mesenteric vasculature of estrogen treated rats. Am J Physiol. 1986; 86: H885-H889.
39. Moghadasian MH, Godin DV. Gender-related antioxidant profiles in the gastrointestinal tract of the rat. Mol Cell Biochem. 1996; 155: 43-49.
40. Kauser K, Sonnenberg D, Tse J, Rubanyi GM. 17β-estradiol attenuates endotoxin-induced excessive nitric oxide production in ovariectomized rats in vivo. Am J Physiol. 1997; 273: H506-H509.
41. Mendelsohn ME, Karas RH. Estrogen and the blood vessel wall. Curr Opin Cardiol. 1994; 9: 619-626.
42. Arnal JF, Clemens S, Pechet C, et al. Ethinylestradiol does not enhance the expression of nitric oxide synthase in bovine endothelial cells but increases the release of bioactive nitric oxide by inhibiting superoxide anion production. Proc Natl Acad Sci U S A. 1996; 93: 4108-4113.
43. De Caterina R, Libby P, Peng HB, et al. Nitric oxide decreases cytokine-induced endothelial activation: nitric oxide selectively reduces expression of adhesion molecules and proinflammatory cytokines. J Clin Invest. 1995; 96: 60-68.
44. Zeihar AM, Fisslthaler B, Schray-Utz B, Busse R. Nitric oxide selectively reduces the expression of adhesion molecules and proinflammatory cytokines. J Clin Invest. 1995; 96: 60-68.