Geldanamycin inhibits hemorrhage-induced increases in caspase-3 activity: Role of inducible nitric oxide synthase

Journal of Applied Physiology

Volumn 103, Issue 3, 2007, Pages 1045-1055

  Kiang, Juliann G ^a,b,c   Bowman, Phillip D ^d   Lu, Xinyue ^c   Li, Yansong ^c   Wu, Brian W ^c   Loh, Horace H ^e   Tsen, K T ^f   Tsokos, George C ^g  

^a ARMED FORCES RADIOBIOLOGY RESEARCH INSTITUTE   (United States)

^b UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^c WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

^d US ARMY INSTITUTE OF SURGICAL RESEARCH   (United States)

^e UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^f ARIZONA STATE UNIVERSITY   (United States)

^g HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Caspase 9; Cytochrome c; Hemorrhagic shock; Jejunum; Lung

Indexed keywords

APOPTOSOME; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE 3; CASPASE 9; CYTOCHROME C; GELDANAMYCIN; INDUCIBLE NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLEEDING; CONTROLLED STUDY; CYTOSOL; DRUG INHIBITION; ENZYME ACTIVITY; GENETIC TRANSFECTION; HEMORRHAGIC SHOCK; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ANOXIA; APOPTOSOMES; BENZOQUINONES; CALCIUM; CASPASE 3; CYTOSOL; HEMORRHAGE; JEJUNUM; LACTAMS, MACROCYCLIC; MALE; MICE; NITRIC OXIDE SYNTHASE TYPE II; PROTO-ONCOGENE PROTEINS C-AKT; SHOCK, HEMORRHAGIC; SIGNAL TRANSDUCTION;

EID: 34548393568     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00100.2007     Document Type: Article

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