Sialic acid, homocysteine and CRP: Potential markers for dementia

Neuroscience Letters

Volumn 465, Issue 3, 2009, Pages 282-284

  Davis, Gershwin ^a   Baboolal, Nelleen ^a   Nayak, Shivanand ^a   McRae, Amanda ^a  

^a UNIVERSITY OF THE WEST INDIES   (Trinidad and Tobago)

Author keywords

Alzheimer's disease; CRP; Dementia; Homocysteine; Sialic acid

Indexed keywords

BIOLOGICAL MARKER; C REACTIVE PROTEIN; HOMOCYSTEINE; SIALIC ACID;

AGED; ALZHEIMER DISEASE; ARTICLE; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DEMENTIA; FEMALE; HUMAN; MALE; MINI MENTAL STATE EXAMINATION; MULTIINFARCT DEMENTIA; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; QUESTIONNAIRE; REFERENCE VALUE; SEX DIFFERENCE;

AGED; ALZHEIMER DISEASE; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; DEMENTIA; FEMALE; HOMOCYSTEINE; HUMANS; MALE; N-ACETYLNEURAMINIC ACID; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 70349782210     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2009.09.035     Document Type: Article

References (33)

1. Central Statistical Office. Statistics at a Glance (2001), Central Statistical Office, Port-of-Spain
2. Chang C.Y., and Silverman D.H. Accuracy of early diagnosis and its impact on the management and course of Alzheimer's disease. Expert Rev. Mol. Diagn. 4 (2004) 63-69
3. Davis G.K., Baboolal N.S., Seales D., Ramchandani J., McKell S., and McRae A. Potential biomarkers for dementia in Trinidad and Tobago. Neurosci. Lett. 424 (2007) 27-30
4. Dik M.G., Jonker C., Hack C.E., Smit J.H., Comijs H.C., and Eikelenboom P. Serum inflammatory proteins and cognitive decline in older persons. Neurology 64 (2005) 1371-1377
5. Feldmann E., and Tornabene J. Diagnosis and treatment of cerebral amyloid angiopathy. Clin. Geriatr. Med. 7 (1991) 617-630
6. Folstein M.F., and McHugh P.R. Mini-mental state: a practical method for grading the state of patients for the clinician. J. Psychiatr. Res. 12 (1975) 189-198
7. Hangloo B., Kaul I., and Zargar H. Serum sialic acid levels in healthy individuals. J. Postgrad. Med. 36 (1990) 140-142
8. Kravitz B.A., Corrada M.M., and Kawas C.H. Elevated C-reactive protein levels are associated with prevalent dementia in the oldest-old. Alzheimers Dement. 5 (2009) 318-323
9. Kuo H.K., Yen C.J., Chang C.H., Kuo C.K., Chen J.H., and Sorond F. Relation of C-reactive protein to stroke, cognitive disorders, and depression in the general population: systematic review and meta-analysis. Lancet Neurol. 4 (2005) 371-380
10. Leske M.C., Wu S.Y., Hyman A., Nemesure B., Yang L., and Schachat A.P. Barbados Eye Study Group, hyperglycemia, blood pressure and the 9-year incidence of diabetic retinopathy: the Barbados Eye Studies. Ophthalmology 112 (2005) 799-805
11. Lindberg G., Eklund G.A., Gullberg B., and Rastam L. Serum sialic acid concentration and cardiovascular mortality. BMJ 302 (1991) 143-146
12. Lindberg G., Rastam G.L., Gulberg B., and Eklud G.A. Serum sialic acid concentration predicts both coronary heart disease and stroke mortality: multivariate analysis including 54 385 men and women during 20.5 year follow up. Int. J. Epidemiol. 21 (1992) 253-257
13. Melajarvi N., Gylling H., and Miettinen T. Sialic acids and the metabolism of low density lipoprotein. J. Lipid Res. 37 (1996) 1625-1631
14. Miller G.J., Maude G.H., and Beckles G.L. Incidence of hypertension and non-insulin dependant diabetes mellitus and associated risk factors in a rapidly developing Caribbean community: the St James survey, Trinidad. J. Epidemiol. Community Health 50 (1996) 497-504
15. Mrak R.E., and Griffin W.S.T. Potential Inflammatory biomarkers in Alzheimer's disease. J. Alzheimers Dis. 8 (2005) 369-375
16. Pickup J.C. Inflammation and activated innate immunity in the pathogenesis of type 2 diabetes. Diabetes Care 27 (2004) 813-823
17. Pickup J.C., Mattock M.B., Cook M.A., Chusney G.D., Burt D., and Fltzgerald A.P. Serum sialic acid concentration and coronary heart disease in NIDDM. Diabetes Care 18 (1995) 1100-1103
18. Plassman B.L., Langa K.M., Fisher G.G., Heeringa S.G., Weir D.R., Ofstedal M.B., Burke J.R., Hurd M.D., Potter G.G., Rodgers W.L., Steffens D.C., Willis R.J., and Wallace R.B. Prevalence of dementia in the United States: the aging, demographics, and memory study. Neuroepidemiology. 29 (2007) 125-132
19. Ravaglia G., Forti P., Maioli F., Chiappelli M., Montesi F., Tumini E., Mariani E., Licastro F., and Patterson C. Inflammatory markers and risk of dementia: the conselice study of brain aging. Neurobiology of Aging 28 (2007) 1810-1820
20. Ringman J.M., Frautschy S.A., Cole G.M., Masterman D.L., and Cummings J.L. A potential role of the curry spice curcumin in Alzheimer's disease. Curr. Alzheimer Res. 2 (2005) 131-136
21. Schram M.T., Euser S.M., de Craen A.J., Witteman J.C., Frölich M., Hofman A., Jolles J., Breteler M.M., and Westendorp R.G. Systemic markers of inflammation and cognitive decline in old age. J. Am. Geriatr. Soc. 55 (2007) 708-716
22. Seshadri S. Elevated plasma homocysteine levels: risk factor or risk marker for the development of dementia and Alzheimer's disease?. J. Alzheimers Dis. 9 (2006) 393-398
23. Seshadri S., Beiser A., Selhub J., Jacques P.F., Rosenberg I.H., D'Agostino R.B., Wilson P.W., and Wolf P.A. Plasma homocysteine as a risk factor for dementia and Alzheimer's disease. N. Engl. J. Med. 346 (2002) 476-483
24. Stewart R., Powell J., Prince M., and Mann A. ACE genotype and cognitive decline in an African-Caribbean population. Neurobiol. Aging 25 (2004) 1369-1375
25. Vogel T., Dali-Youcef N., Kaltenbach G., and Andrès E. Homocysteine, vitamin B12, folate and cognitive functions: a systematic and critical review of the literature. Int. J. Clin. Pract. 63 (2009) 1061-1067
26. Wang S.S., Rymer D.L., and Good T.A. Reduction in cholesterol and sialic acid content protects cells from the toxic effects of β-amyloid peptides. J. Biol. Chem. 276 (2001) 42027-42034
27. Welch G.N., and Loscalzo J. Homocysteine and atherothrombosis. N. Engl. J. Med. 338 (1998) 1042-1050
28. Winzler R.T. Determination of serum glycoproteins. In: Glick D.T. (Ed). Methods of Biochemical analysis. II (1955), Interscience publishers, Inc., New York 298
29. Yaffe K. Metabolic syndrome and cognitive disorders: is the sum greater than its parts?. Alzheimer Dis. Assoc. Disord. 211 (2007) 67-71
30. Yaffe K., Kanaya A., Lindquist K., Simonsick E., Harris T., Shorr R., Tylavsky F., and Newman A. The metabolic syndrome, inflammation, and the risk of cognitive decline. JAMA 292 (2004) 2237-2242
31. Yamada M. Cerebral amyloid angiopathy: an overview. Neuropathology 20 (2000) 8-22
32. Yarema K. The sialic acid pathway in human cells (2006), John Hopkins University, Baltimore
33. Yasojima K., Schwab C., McGeer E.G., and McGeer P.L. Human neurons generate C-reactive protein and amyloid P: upregulation in Alzheimer's disease. Brain Res. 887 (2000) 80-89