Blood compatibility and in vitro transfection studies on cationically modified pullulan for liver cell targeted gene delivery

Biomaterials

Volumn 30, Issue 34, 2009, Pages 6655-6664

  Rekha, M R ^a   Sharma, Chandra P ^a  

^a SREE CHITRA TIRUNAL INSTITUTE FOR MEDICAL SCIENCES AND TECHNOLOGY   (India)

Author keywords

Blood compatibility; Gene delivery; In vitro transfection; Pullulan

Indexed keywords

AMMONIUM CHLORIDE; BINDING AFFINITIES; BLOOD COMPATIBILITY; CATIONIC GROUPS; GEL-RETARDATION ASSAY; GENE DELIVERY; HEPATOCYTES; IN VITRO TRANSFECTION; IN-VITRO; IN-VIVO; LIVER CELLS; NANOCOMPLEXES; NONVIRAL VECTORS; PHYSICO-CHEMICAL CHARACTERIZATION; POLYETHYLENEIMINE; POSITIVE CHARGES; PULLULAN; PULLULANS; TARGETED GENE DELIVERY; TRIMETHYL;

AMMONIUM COMPOUNDS; BINDING ENERGY; BLOOD; BLOOD SUBSTITUTES; CELL MEMBRANES; CHLORINE COMPOUNDS; CYTOTOXICITY; GENE TRANSFER; LIVER; NUCLEIC ACIDS; POLYETHYLENES; ZETA POTENTIAL;

DYES;

CATIONIC PULLULAN; POLYETHYLENEIMINE; PULLULAN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BLOOD COMPATIBILITY; COMPLEX FORMATION; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; IN VITRO GENE TRANSFER; LIVER CELL; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; TOXICITY TESTING; ZETA POTENTIAL;

ANIMALS; BLOOD GROUPING AND CROSSMATCHING; CATIONS; GLUCANS; HUMANS; LIVER; MAGNETIC RESONANCE SPECTROSCOPY; MICE; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TRANSFECTION;

MUS;

EID: 70349765514     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2009.08.029     Document Type: Article

References (38)

1. Curiel D.T., Gerritsen W.R., and Krul M.R. Progress in cancer gene therapy. Cancer Gene Ther 7 (2000) 1197-1199
2. El-Aneed A. An overview of current delivery systems in cancer gene therapy. J Control Release 94 (2004) 1-14
3. Simon R.H., Engelhardt J.F., Yang Y., Zepeda M., Weber-Pendelton S., Grossman M., et al. Adenovirus-mediated gene transfer of the CFTR gene to the lung of non-human primates: a toxicity study. Hum Gene Ther 4 (1993) 771-780
4. Lee M., and Kim S.W. Polymeric gene carriers. Pharmaceutical News 9 (2002) 407-415
5. Lv H., Zhang S., Wang B., Cui S., and Yan J. Toxicity of cationic lipids and cationic polymers in gene delivery. J Control Release 114 (2006) 100-109
6. Masago K., Itaka K., Nishiyama N., Chung U., and Kataoka K. Gene delivery with biocompatible cationic polymer: pharmacogenomic analysis on cell bioactivity. Biomaterials 28 (2007) 5169-5175
7. Liang B., He M.-, Chan C.-y., Chen Y.-c., Li X.-P., Li Y., et al. The use of folate-PEG-grafted-hybranched-PEI nonviral vector for the inhibition of glioma growth in the rat. Biomaterials 30 (2009) 4014-4020
8. Kainthan R.K., Gnanamani M., Ganguli M., Ghosh T., Brooks D.E., Souvik M., et al. Blood compatibility of novel water solube hyperbranched polyglycerol based multivalent cationic polymers and their interaction with DNA. Biomaterials 27 (2006) 5377-5390
9. Kimoto T., Shibuya T., and Shiobara S. Safety studies of a novel starch, pullulan: chronic toxicity in rats and bacterial mutagenicity. Food Chem Toxicol 35 (1997) 323-329
10. Akiyoshi K., Kobayashi S., Schibe S., Mix D., Baudys M., and Kim S.W. Self-assembled hydrogel nanoparticle of cholesterol-bearing pullulan as a carrier of protein drugs: complexation and stabilization of insulin. J Control Release 54 (1998) 313-320
11. Na K., and Bae Y.H. Self-assembled hydrogel nanoparticles responsive to tumor extracellular pH from pullulan derivative/sulfonamide conjugate: characterization, aggregation, and adriamycin release in vitro. Pharm Res 19 (2002) 681-687
12. Kaneo Y., Tanaka T., Nakano T., and Yamaguchi Y. Evidence for receptor-mediated hepatic uptake of pullulan in rats. J Control Release 70 (2001) 365-373
13. Tanaka T., Fujishima Y., Hanano S., and Kaneo Y. Intracellular disposition of polysaccharides in rat liver parenchymal and nonparenchymal cells. Int J Pharm 286 (2004) 9-17
14. Nogusa H., Yamamoto K., Yano T., Kajiki M., Hamana H., and Okuno S. Distribution characteristics of carboxymethylpullulan-peptide-doxorubicin conjugates in tumor-bearing rats: different sequence of peptide spacers and doxorubicin contents. Biol Pharm Bull 23 (2000) 621-626
15. Jo J., Yamamoto M., Matsumoto K., Nakamura T., and Tabata Y. Liver targeting of plasmid DNA with a cationized pullulan for tumor suression. J Nanosci Nanotechnol 6 (2006) 2853-2859
16. Juan A.S., Hlawaty H., Chaubet F., Letourneur D., and Feldman L.J. Cationized pullulan 3D matrices as new materials for gene transfer. J Biomed Mater Res 82A (2007) 354-362
17. Bendoraitiene J., Kavaliauskaite R., Klimaviciute R., and Zemaitaitis A. Peculiarities of starch cationization with glycidyltrimethylammonium chloride. Starch/Stärke 58 (2006) 623-631
18. Murthy N., Robichaud J.R., Tirrell D.A., Stayton P.S., and Hoffman A.S. The design and synthesis of polymers for eukaryotic membrane disruption. J Control Release 61 (1999) 137-143
19. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 (1970) 680-685
20. Kanchan V., and Panda A.K. Interactions of antigen-loaded polylactide particles with macrophages and their correlation with the immune response. Biomaterials 28 (2007) 5344-5357
21. Rejman J., Bragonzi A., and Conese M. Role of clathrin- and caveolaemediated endocytosis in gene transfer mediated by lipo- and polyplexes. Mol Ther 12 (2005) 468-474
22. Orlandi P.A., and Fishman P.H. Filipin-dependent inhibition of cholera toxin: evidence for toxin internalization and activation through caveolae-like domains. J Cell Biol 141 (1998) 905-915
23. Xu Y., Du Y., Huang R., and Gao L. Preparation and modification of N-(2-hydroxyl) propyl-3-trimethyl ammonium chitosan chloride nanoparticle as a protein carrier. Biomaterials 24 (2003) 5015-5022
24. Chein S. Biohysical behaviour of red cells in suspensions. In: Surgenor D.M. (Ed). Red blood cell (1975), AP, New York 1032-1121
25. Morgan M., Larvin V.L., and Pearson J.L. Biochemical characterization of polycation-induced cytotoxicity to human vascular endothelial cells. J Cell Sci 94 (1989) 553-559
26. Fischer D., Li Y., Ahlemeyer B., Krieglstein J., and Kissel T. In vitro cytotoxicity testing of polycations: influence of polymer structure on cell viability and haemolysis. Biomaterials 24 (2003) 1121-1131
27. Jumaa M., Furkert F.H., and Muller B.W. A new lipid emulsion formulation with high antimicrobial efficacy using chitosan. Eur J Pharm Biopharm 53 (2002) 115-123
28. In: Silver F.H. (Ed). Biomaterials medical devices and tissue engineering: an integrated approach (1994), Chapman & Hall, London 153-192
29. Plank C., Mechtler K., Szoka F.C.J., and Wagner E. Activation of the complement system by synthetic DNA complexes: a potential barrier for intravenous gene delivery. Human Gene Therapy 7 (1996) 1437-1446
30. Todaa M., Kitazawa T., Hirata I., Hirano Y., and Iwata H. Complement activation on surfaces carrying amino groups. Biomaterials 29 (2008) 407-417
31. Ogris M., Brunner S., Schuller S., Kircheis R., and Wagner E. PEGylated DNA/transferrin-PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery. Gene Ther 6 (1999) 595-605
32. Hed J., Gallen G., Johansson S.G., and Larsson P. The use of fluorescence quenching in flow cytofluorometry to measure the attachment and ingestion phases in phagocytosis in peripheral blood without prior cell separation. J Immunol Methods 101 (1987) 119-125
33. Teramura Y., Kaneda Y., Totani T., and Iwata H. Behaviour of synthetic polymers immobilized on a cell membrane. Biomaterials 29 (2008) 1345-1355
34. Gonçalves C., Mennesson E., Fuchs R., Gorvel J.-P., Midoux P., and Pichon C. Macropinocytosis of polyplexes and recycling of plasmid via the clathrin-dependent pathway impair the transfection efficiency of human hepatocarcinoma cells. Mol Ther 10 (2004) 373-385
35. 1H NMR relaxation time. J Mol Struct 602-603 (2002) 473-483
36. In: Harris J.M. (Ed). Polyethylene glycol chemistry: biotechnical and biomedical applications (1992), Plenum Press, New York
37. Godbey W.T., Wu K.K., and Mikos A.G. Poly (ethyleneimine)-mediated gene delivery affects endothelial cell function and viability. Biomaterials 22 (2001) 471-480
38. Kanatani I., Ikai T., Okazaki A., J-i J., Yamamoto M., Imamura M., et al. Efficient gene transfer by pullulan-spermine occurs through both clathrin- and raft/caveolae-dependent mechanisms. J Control Release 116 (2006) 75-82