Self-assembled hydrogel nanoparticle of cholesterol-bearing pullulan as a carrier of protein drugs: Complexation and stabilization of insulin

Journal of Controlled Release

Volumn 54, Issue 3, 1998, Pages 313-320

  Akiyoshi, Kazunari ^a   Kobayashi, Seiichi ^a   Shichibe, Shozo ^a   Mix, Don ^b   Baudys, Miroslav ^b   Wan Kim, Sung ^b   Sunamoto, Junzo ^a  

^a KYOTO UNIVERSITY   (Japan)

^b UNIVERSITY OF UTAH   (United States)

Author keywords

Cholesterol bearing pullulan; Hydrogel nanoparticle; Hydrophobized polysaccharide; Insulin; Protein drug formulation

Indexed keywords

BOVINE SERUM ALBUMIN; DRUG CARRIER; INSULIN; NANOPARTICLE; PULLULAN;

ANIMAL EXPERIMENT; ARTICLE; COMPLEX FORMATION; DRUG FORMULATION; DRUG RELEASE; DRUG STABILITY; GEL PERMEATION CHROMATOGRAPHY; HYDROGEL; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; CHOLESTEROL; CHROMATOGRAPHY, GEL; CHYMOTRYPSIN; CIRCULAR DICHROISM; COLLOIDS; DRUG CARRIERS; DRUG STABILITY; GLUCANS; HYDROGEL; HYPOGLYCEMIC AGENTS; INSULIN; MALE; PARTICLE SIZE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0032516710     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(98)00017-0     Document Type: Article

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