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Volumn 86, Issue 4, 2009, Pages 779-793

Obstacles to the successful development of an efficacious T cell-inducing HIV-1 vaccine

Author keywords

Adenovirus vectors; Animal models; Correlates of protection; STEP trial

Indexed keywords

ADENOVIRUS VECTOR; BACTERIAL VECTOR; DNA VACCINE; EPITOPE; GAG PROTEIN; GLYCOPROTEIN E1; GLYCOPROTEIN GP 120; GLYCOPROTEIN GP 160; HLA ANTIGEN CLASS 1; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; MODIFIED VACCINIA VIRUS ANKARA 5T4 VACCINE; NEF PROTEIN; NEUTRALIZING ANTIBODY; PARVOVIRUS VECTOR; PLASMID VECTOR; POL PROTEIN; PROTEINASE; VIRUS ENVELOPE PROTEIN; VIRUS PROTEIN;

EID: 70349647523     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0209094     Document Type: Review
Times cited : (14)

References (158)
  • 2
    • 38349151669 scopus 로고    scopus 로고
    • HIV-1 T-cell vaccines: Evaluating the next step
    • Pantaleo, G. (2008) HIV-1 T-cell vaccines: evaluating the next step. Lancet Infect. Dis. 8, 82-83.
    • (2008) Lancet Infect. Dis. , vol.8 , pp. 82-83
    • Pantaleo, G.1
  • 3
    • 38949170716 scopus 로고    scopus 로고
    • Prospects of HIV env modification as an approach to HIV vaccine design
    • Hu, S. L., Stamatatos, L. (2007) Prospects of HIV env modification as an approach to HIV vaccine design. Curr. HIV Res. 5, 507-513.
    • (2007) Curr. HIV Res , vol.5 , pp. 507-513
    • Hu, S.L.1    Stamatatos, L.2
  • 9
    • 43949124825 scopus 로고    scopus 로고
    • HLA class I-restricted T-cell responses may contribute to the control of human immunodeficiency virus infection, but such responses are not always necessary for long-term virus control
    • DOI 10.1128/JVI.02176-07
    • Emu, B., Sinclair, E., Hatano, H., Ferre, A., Shacklett, B., Martin, J. N., McCune, J. M., Deeks, S. G. (2008) HLA class I-restricted T-cell responses may contribute to the control of human immunodeficiency virus infection, but such responses are not always necessary for long-term virus control. J. Virol. 82, 5398-5407. (Pubitemid 351705247)
    • (2008) Journal of Virology , vol.82 , Issue.11 , pp. 5398-5407
    • Emu, B.1    Sinclair, E.2    Hatano, H.3    Ferre, A.4    Shacklett, B.5    Martin, J.N.6    McCune, J.M.7    Deeks, S.G.8
  • 12
    • 37349114897 scopus 로고    scopus 로고
    • Adherence as therapeutic citizenship: Impact of the history of access to antiretroviral drugs on adherence to treatment
    • DOI 10.1097/01.aids.0000298100.48990.58, PII 0000203020071000500005
    • Nguyen, V. K., Ako, C. Y., Niamba, P., Sylla, A., Tiendrebeogo, I. (2007) Adherence as therapeutic citizenship: impact of the history of access to antiretroviral drugs on adherence to treatment. AIDS 21 (Suppl. 5), S31-S35. (Pubitemid 350294904)
    • (2007) AIDS , vol.21 , Issue.SUPPL. 5
    • Nguyen, V.-K.1    Ako, C.Y.2    Niamba, P.3    Sylla, A.4    Tiendrebeogo, I.5
  • 13
    • 33847414203 scopus 로고    scopus 로고
    • Ten years of highly active antiretroviral therapy for HIV infection
    • Chen, L. F., Hoy, J., Lewin, S. R. (2007) Ten years of highly active antiretroviral therapy for HIV infection. Med. J. Aust. 186, 146-151. (Pubitemid 46331200)
    • (2007) Medical Journal of Australia , vol.186 , Issue.3 , pp. 146-151
    • Chen, L.F.1    Hoy, J.2    Lewin, S.R.3
  • 18
    • 38949186531 scopus 로고    scopus 로고
    • Roles of HIV-1 env variable regions in viral neutralization and vaccine development
    • Pinter, A. (2007) Roles of HIV-1 env variable regions in viral neutralization and vaccine development. Curr. HIV Res. 5, 542-553.
    • (2007) Curr. HIV Res , vol.5 , pp. 542-553
    • Pinter, A.1
  • 21
    • 0037192575 scopus 로고    scopus 로고
    • Naturally HIV-1 seroconverters with lowest viral load have best prognosis, but in time lose control of viraemia
    • DOI 10.1097/00002030-200203290-00016
    • Goudsmit, J., Bogaards, J. A., Jurriaans, S., Schuitemaker, H., Lange, J. M., Coutinho, R. A., Weverling, G. J. (2002) Naturally HIV-1 sero-converters with lowest viral load have best prognosis, but in time lose control of viremia. AIDS 16, 791-793. (Pubitemid 34274471)
    • (2002) AIDS , vol.16 , Issue.5 , pp. 791-793
    • Goudsmit, J.1    Bogaards, J.A.2    Jurriaans, S.3    Schuitemaker, H.4    Lange, J.M.A.5    Coutinho, R.A.6    Weverling, G.J.7
  • 23
    • 0028122380 scopus 로고
    • Shutting down HIV
    • Koup, R. A., Ho, D. D. (1994) Shutting down HIV. Nature 370, 416.
    • (1994) Nature , vol.370 , pp. 416
    • Koup, R.A.1    Ho, D.D.2
  • 28
    • 63449124466 scopus 로고    scopus 로고
    • Emerging concepts in the immunopathogenesis of AIDS
    • Douek, D. C., Roederer, M., Koup, R. A. (2008) Emerging concepts in the immunopathogenesis of AIDS. Annu. Rev. Med. 60, 471-484.
    • (2008) Annu. Rev. Med. , vol.60 , pp. 471-484
    • Douek, D.C.1    Roederer, M.2    Koup, R.A.3
  • 29
    • 44649201289 scopus 로고    scopus 로고
    • HIV infection and the gastrointestinal immune system
    • Brenchley, J. M., Douek, D. C. (2008) HIV infection and the gastrointestinal immune system. Mucosal Immunol. 1, 23-30.
    • (2008) Mucosal Immunol , vol.1 , pp. 23-30
    • Brenchley, J.M.1    Douek, D.C.2
  • 30
    • 59149086183 scopus 로고    scopus 로고
    • AIDS pathogenesis: A tale of two monkeys
    • Silvestri, G. (2008) AIDS pathogenesis: a tale of two monkeys. J. Med. Primatol. 37 (Suppl. 2), 6-12.
    • (2008) J. Med. Primatol. , vol.37 , Issue.SUPPL. 2 , pp. 6-12
    • Silvestri, G.1
  • 31
    • 57449099742 scopus 로고    scopus 로고
    • Immunity in natural SIV infections
    • Silvestri, G. (2009) Immunity in natural SIV infections. J. Intern. Med. 265, 97-109.
    • (2009) J. Intern. Med. , vol.265 , pp. 97-109
    • Silvestri, G.1
  • 35
    • 13544261553 scopus 로고    scopus 로고
    • DNA prime Listeria boost induces a cellular immune response to SIV antigens in the rhesus macaque model that is capable of limited suppression of SIV239 viral replication
    • DOI 10.1016/j.virol.2004.12.026
    • Boyer, J. D., Robinson, T. M., Maciag, P. C., Peng, X., Johnson, R. S., Pavlakis, G., Lewis, M. G., Shen, A., Siliciano, R., Brown, C. R., Weiner, D. B., Paterson, Y. (2005) DNA prime Listeria boost induces a cellular immune response to SIV antigens in the rhesus macaque model that is capable of limited suppression of SIV239 viral replication. Virology 333, 88-101. (Pubitemid 40222193)
    • (2005) Virology , vol.333 , Issue.1 , pp. 88-101
    • Boyer, J.D.1    Robinson, T.M.2    Maciag, P.C.3    Peng, X.4    Johnson, R.S.5    Pavlakis, G.6    Lewis, M.G.7    Shen, A.8    Siliciano, R.9    Brown, C.R.10    Weiner, D.B.11    Paterson, Y.12
  • 37
    • 17144465337 scopus 로고    scopus 로고
    • Immunization of rhesus macaques with a DNA prime/modified vaccinia virus Ankara boost regimen induces broad simian immunodeficiency virus (SIV)-specific T-cell responses and reduces initial viral replication but does not prevent disease progression following challenge with pathogenic SIVmac239
    • DOI 10.1128/JVI.76.14.7187-7202.2002
    • Horton, H., Vogel, T. U., Carter, D. K., Vielhuber, K., Fuller, D. H., Shipley, T., Fuller, J. T., Kunstman, K. J., Sutter, G., Montefiori, D. C., Erfle, V., Desrosiers, R. C., Wilson, N., Picker, L. J., Wolinsky, S. M., Wang, C., Allison, D. B., Watkins, D. I. (2002) Immunization of rhesus macaques with a DNA prime/modified vaccinia virus Ankara boost regimen induces broad simian immunodeficiency virus (SIV)-specific T-cell responses and reduces initial viral replication but does not prevent disease progression following challenge with pathogenic SIVmac239. J. Virol. 76, 7187-7202. (Pubitemid 41246232)
    • (2002) Journal of Virology , vol.76 , Issue.14 , pp. 7187-7202
    • Horton, H.1    Vogel, T.U.2    Carter, D.K.3    Vielhuber, K.4    Fuller, D.H.5    Shipley, T.6    Fuller, J.T.7    Kunstman, K.J.8    Sutter, G.9    Montefiori, D.C.10    Erfle, V.11    Desrosiers, R.C.12    Wilson, N.13    Picker, L.J.14    Wolinsky, S.M.15    Wang, C.16    Allison, D.B.17    Watkins, D.I.18
  • 46
    • 0035501136 scopus 로고    scopus 로고
    • Vaccine-elicited immune responses prevent clinical AIDS in SHIV(89.6P)-infected rhesus monkeys
    • Barouch, D. H., Fu, T. M., Montefiori, D. C., Lewis, M. G., Shiver, J. W., Letvin, N. L. (2001) Vaccine-elicited immune responses prevent clinical AIDS in SHIV(89.6P)-infected rhesus monkeys. Immunol. Lett. 79, 57-61.
    • (2001) Immunol. Lett. , vol.79 , pp. 57-61
    • Barouch, D.H.1    Fu, T.M.2    Montefiori, D.C.3    Lewis, M.G.4    Shiver, J.W.5    Letvin, N.L.6
  • 49
    • 0142154176 scopus 로고    scopus 로고
    • Immunogenicity in pig-tailed macaques of poliovirus replicons expressing HIV-1 and SIV antigens and protection against SHIV-89.6P disease
    • DOI 10.1016/S0042-6822(03)00546-4
    • Fultz, P. N., Stallworth, J., Porter, D., Novak, M., Anderson, M. J., Morrow, C. D. (2003) Immunogenicity in pig-tailed macaques of poliovirus replicons expressing HIV-1 and SIV antigens and protection against SHIV-89.6P disease. Virology 315, 425-437. (Pubitemid 37324633)
    • (2003) Virology , vol.315 , Issue.2 , pp. 425-437
    • Fultz, P.N.1    Stallworth, J.2    Porter, D.3    Novak, M.4    Anderson, M.J.5    Morrow, C.D.6
  • 50
    • 0035811833 scopus 로고    scopus 로고
    • Protection from immunodeficiency virus challenges in rhesus macaques by multicomponent DNA immunization
    • DOI 10.1006/viro.2001.0958
    • Kim, J. J., Yang, J. S., Nottingham, L. K., Lee, D. J., Lee, M., Manson, K. H., Wyand, M. S., Boyer, J. D., Ugen, K. E., Weiner, D. B. (2001) Protection from immunodeficiency virus challenges in rhesus macaques by multicomponent DNA immunization. Virology 285, 204-217. (Pubitemid 32641882)
    • (2001) Virology , vol.285 , Issue.2 , pp. 204-217
    • Kim, J.J.1    Yang, J.-S.2    Nottingham, L.K.3    Lee, D.J.4    Lee, M.5    Manson, K.H.6    Wyand, M.S.7    Boyer, J.D.8    Ugen, K.E.9    Weiner, D.B.10
  • 52
    • 0036785549 scopus 로고    scopus 로고
    • Slowly declining levels of viral RNA and DNA in DNA/recombinant modified vaccinia virus Ankara-vaccinated macaques with controlled simian-human immunodeficiency virus SHIV-89.6P challenges
    • Tang, Y., Villinger, F., Staprans, S. I., Amara, R. R., Smith, J. M., Herndon, J. G., Robinson, H. L. (2002) Slowly declining levels of viral RNA and DNA in DNA/recombinant modified vaccinia virus Ankara-vaccinated macaques with controlled simian-human immunodeficiency virus SHIV-89.6P challenges. J. Virol. 76, 10147-10154.
    • (2002) J. Virol. , vol.76 , pp. 10147-10154
    • Tang, Y.1    Villinger, F.2    Staprans, S.I.3    Amara, R.R.4    Smith, J.M.5    Herndon, J.G.6    Robinson, H.L.7
  • 53
    • 0036129320 scopus 로고    scopus 로고
    • AIDS vaccine models: Challenging challenge viruses
    • Feinberg, M. B., Moore, J. P. (2002) AIDS vaccine models: challenging challenge viruses. Nat. Med. 8, 207-210.
    • (2002) Nat. Med. , vol.8 , pp. 207-210
    • Feinberg, M.B.1    Moore, J.P.2
  • 57
    • 38049027445 scopus 로고    scopus 로고
    • Improved protection against simian immunodeficiency virus mucosal challenge in macaques primed with a DNA vaccine and boosted with the recombinant modified vaccinia virus Ankara and recombinant Semliki Forest virus
    • Martinon, F., Brochard, P., Ripaux, M., Delache, B., Auregan, G., Vaslin, B., Le Grand, R. (2008) Improved protection against simian immunodeficiency virus mucosal challenge in macaques primed with a DNA vaccine and boosted with the recombinant modified vaccinia virus Ankara and recombinant Semliki Forest virus. Vaccine 26, 532-545.
    • (2008) Vaccine , vol.26 , pp. 532-545
    • Martinon, F.1    Brochard, P.2    Ripaux, M.3    Delache, B.4    Auregan, G.5    Vaslin, B.6    Le Grand, R.7
  • 59
    • 0033044138 scopus 로고    scopus 로고
    • Protection of macaques against intrarectal infection by a combination immunization regimen with recombinant simian immunodeficiency virus SIVmne gp160 vaccines
    • Polacino, P., Stallard, V., Montefiori, D. C., Brown, C. R., Richardson, B. A., Morton, W. R., Benveniste, R. E., Hu, S. L. (1999) Protection of macaques against intrarectal infection by a combination immunization regimen with recombinant simian immunodeficiency virus SIVmne gp160 vaccines. J. Virol. 73, 3134-3146. (Pubitemid 29135704)
    • (1999) Journal of Virology , vol.73 , Issue.4 , pp. 3134-3146
    • Polacino, P.1    Stallard, V.2    Montefiori, D.C.3    Brown, C.R.4    Richardson, B.A.5    Morton, W.R.6    Benveniste, R.E.7    Hu, S.-L.8
  • 61
    • 0032146171 scopus 로고    scopus 로고
    • Protective immunity induced by live attenuated simian immunodeficiency virus
    • DOI 10.1016/S0952-7915(98)80118-0
    • Johnson, R. P., Desrosiers, R. C. (1998) Protective immunity induced by live attenuated simian immunodeficiency virus. Curr. Opin. Immunol. 10, 436-443. (Pubitemid 28393827)
    • (1998) Current Opinion in Immunology , vol.10 , Issue.4 , pp. 436-443
    • Johnson, R.P.1    Desrosiers, R.C.2
  • 62
    • 41949104713 scopus 로고    scopus 로고
    • Vaccine protection by live, attenuated simian immunodeficiency virus in the absence of high-titer antibody responses and high-frequency cellular immune responses measurable in the periphery
    • Mansfield, K., Lang, S. M., Gauduin, M. C., Sanford, H. B., Lifson, J. D., Johnson, R. P., Desrosiers, R. C. (2008) Vaccine protection by live, attenuated simian immunodeficiency virus in the absence of high-titer antibody responses and high-frequency cellular immune responses measurable in the periphery. J. Virol. 82, 4135-4148.
    • (2008) J. Virol. , vol.82 , pp. 4135-4148
    • Mansfield, K.1    Lang, S.M.2    Gauduin, M.C.3    Sanford, H.B.4    Lifson, J.D.5    Johnson, R.P.6    Desrosiers, R.C.7
  • 63
    • 0036827973 scopus 로고    scopus 로고
    • Live, attenuated simian immunodeficiency virus SIVmac-M4, with point mutations in the Env transmembrane protein intracytoplasmic domain, provides partial protection from mucosal challenge with pathogenic SIVmac251
    • DOI 10.1128/JVI.76.22.11365-11378.2002
    • Shacklett, B. L., Shaw, K. E., Adamson, L. A., Wilkens, D. T., Cox, C. A., Montefiori, D. C., Gardner, M. B., Sonigo, P., Luciw, P. A. (2002) Live, attenuated simian immunodeficiency virus SIVmac-M4, with point mutations in the env transmembrane protein intracytoplasmic domain, provides partial protection from mucosal challenge with pathogenic SIVmac251. J. Virol. 76, 11365-11378. (Pubitemid 35231292)
    • (2002) Journal of Virology , vol.76 , Issue.22 , pp. 11365-11378
    • Shacklett, B.L.1    Shaw, K.E.S.2    Adamson, L.A.3    Wilkens, D.T.4    Cox, C.A.5    Montefiori, D.C.6    Gardner, M.B.7    Sonigo, P.8    Luciw, P.A.9
  • 64
    • 0033029835 scopus 로고    scopus 로고
    • β-chemokine production in macaques vaccinated with live attenuated virus correlates with protection against simian immunodeficiency virus (SIVsm) challenge
    • Ahmed, R. K., Nilsson, C., Wang, Y., Lehner, T., Biberfeld, G., Thorstensson, R. (1999) β-Chemokine production in macaques vaccinated with live attenuated virus correlates with protection against simian immunodeficiency virus (SIVsm) challenge. J. Gen. Virol. 80, 1569-1574. (Pubitemid 29319846)
    • (1999) Journal of General Virology , vol.80 , Issue.7 , pp. 1569-1574
    • Ahmed, R.K.S.1    Nilsson, C.2    Wang, Y.3    Lehner, T.4    Biberfeld, G.5    Thorstensson, R.6
  • 65
    • 0028914161 scopus 로고
    • Cross-protective immune responses induced in rhesus macaques by immunization with attenuated macrophage-tropic simian immunodeficiency virus
    • Clements, J. E., Montelaro, R. C., Zink, M. C., Amedee, A. M., Miller, S., Trichel, A. M., Jagerski, B., Hauer, D., Martin, L. N., Bohm, R. P., et al. (1995) Cross-protective immune responses induced in rhesus macaques by immunization with attenuated macrophage-tropic simian immunodeficiency virus. J. Virol. 69, 2737-2744.
    • (1995) J. Virol. , vol.69 , pp. 2737-2744
    • Clements, J.E.1    Montelaro, R.C.2    Zink, M.C.3    Amedee, A.M.4    Miller, S.5    Trichel, A.M.6    Jagerski, B.7    Hauer, D.8    Martin, L.N.9    Bohm, R.P.10
  • 66
    • 1542287436 scopus 로고    scopus 로고
    • Repeated Low-Dose Mucosal Simian Immunodeficiency Virus SIVmac239 Challenge Results in the Same Viral and Immunological Kinetics as High-Dose Challenge: A Model for the Evaluation of Vaccine Efficacy in Nonhuman Primates
    • DOI 10.1128/JVI.78.6.3140-3144.2004
    • McDermott, A. B., Mitchen, J., Piaskowski, S., De Souza, I., Yant, L. J., Stephany, J., Furlott, J., Watkins, D. I. (2004) Repeated low-dose mucosal simian immunodeficiency virus SIVmac239 challenge results in the same viral and immunological kinetics as high-dose challenge: a model for the evaluation of vaccine efficacy in nonhuman primates. J. Virol. 78, 3140-3144. (Pubitemid 38314372)
    • (2004) Journal of Virology , vol.78 , Issue.6 , pp. 3140-3144
    • McDermott, A.B.1    Mitchen, J.2    Piaskowski, S.3    De Souza, I.4    Yant, L.J.5    Stephany, J.6    Furlott, J.7    Watkins, D.I.8
  • 70
    • 57149096855 scopus 로고    scopus 로고
    • Combining DNA technologies and different modes of immunization for induction of humoral and cellular anti-HIV-1 immune responses
    • Brave, A., Hallengard, D., Malm, M., Blazevic, V., Rollman, E., Stanescu, I., Krohn, K. (2009) Combining DNA technologies and different modes of immunization for induction of humoral and cellular anti-HIV-1 immune responses. Vaccine 27, 184-186.
    • (2009) Vaccine , vol.27 , pp. 184-186
    • Brave, A.1    Hallengard, D.2    Malm, M.3    Blazevic, V.4    Rollman, E.5    Stanescu, I.6    Krohn, K.7
  • 75
    • 67349094564 scopus 로고    scopus 로고
    • Novel SIVmac DNA vaccines encoding Env, Pol and Gag consensus proteins elicit strong cellular immune responses in cynomolgus macaques
    • Yan, J., Hokey, D. A., Morrow, M. P., Corbitt, N., Harris, K., Harris, D., Weiner, D. B. (2009) Novel SIVmac DNA vaccines encoding Env, Pol and Gag consensus proteins elicit strong cellular immune responses in cynomolgus macaques. Vaccine 27, 3260-3266.
    • (2009) Vaccine , vol.27 , pp. 3260-3266
    • Yan, J.1    Hokey, D.A.2    Morrow, M.P.3    Corbitt, N.4    Harris, K.5    Harris, D.6    Weiner, D.B.7
  • 76
    • 40549088502 scopus 로고    scopus 로고
    • Design, construction, and characterization of a multigenic modified vaccinia Ankara candidate vaccine against human immunodeficiency virus type 1 subtype C/B′
    • Chen, Z., Huang, Y., Zhao, X., Ba, L., Zhang, W., Ho, D. D. (2008) Design, construction, and characterization of a multigenic modified vaccinia Ankara candidate vaccine against human immunodeficiency virus type 1 subtype C/B′. J. Acquir. Immune Defic. Syndr. 47, 412-421.
    • (2008) J. Acquir. Immune Defic. Syndr. , vol.47 , pp. 412-421
    • Chen, Z.1    Huang, Y.2    Zhao, X.3    Ba, L.4    Zhang, W.5    Ho, D.D.6
  • 77
    • 67349254687 scopus 로고    scopus 로고
    • Recombinant measles viruses expressing single or multiple antigens of human immunode- Ficiency virus (HIV-1) induce cellular and humoral immune responses
    • Liniger, M., Zuniga, A., Morin, T. N., Combardiere, B., Marty, R., Wiegand, M., Ilter, O., Knuchel, M., Naim, H. Y. (2009) Recombinant measles viruses expressing single or multiple antigens of human immunode- ficiency virus (HIV-1) induce cellular and humoral immune responses. Vaccine 27, 3299-3305.
    • (2009) Vaccine , vol.27 , pp. 3299-3305
    • Liniger, M.1    Zuniga, A.2    Morin, T.N.3    Combardiere, B.4    Marty, R.5    Wiegand, M.6    Ilter, O.7    Knuchel, M.8    Naim, H.Y.9
  • 79
    • 4644318756 scopus 로고    scopus 로고
    • Adenoviruses as vaccine vectors
    • Tatsis, N., Ertl, H. C. (2004) Adenoviruses as vaccine vectors. Mol. Ther. 10, 616-629.
    • (2004) Mol. Ther. , vol.10 , pp. 616-629
    • Tatsis, N.1    Ertl, H.C.2
  • 82
    • 55049107224 scopus 로고    scopus 로고
    • Potent specific immune responses induced by prime-boost-boost strategies based on DNA, adenovirus, and Sendai virus vectors expressing gag gene of Chinese HIV-1 subtype B
    • Yu, S., Feng, X., Shu, T., Matano, T., Hasegawa, M., Wang, X., Ma, H., Li, H., Li, Z., Zeng, Y. (2008) Potent specific immune responses induced by prime-boost-boost strategies based on DNA, adenovirus, and Sendai virus vectors expressing gag gene of Chinese HIV-1 subtype B. Vaccine 26, 6124-6131.
    • (2008) Vaccine , vol.26 , pp. 6124-6131
    • Yu, S.1    Feng, X.2    Shu, T.3    Matano, T.4    Hasegawa, M.5    Wang, X.6    Ma, H.7    Li, H.8    Li, Z.9    Zeng, Y.10
  • 85
    • 58549089904 scopus 로고    scopus 로고
    • AIDSVAX immunization induces HIV-specific CD8+ T-cell responses in high-risk, HIV-negative volunteers who subsequently acquire HIV infection
    • Jones, N. G., DeCamp, A., Gilbert, P., Peterson, M. L., Gurwith, M., Cao, H. (2009) AIDSVAX immunization induces HIV-specific CD8+ T-cell responses in high-risk, HIV-negative volunteers who subsequently acquire HIV infection. Vaccine 27, 1136-1140.
    • (2009) Vaccine , vol.27 , pp. 1136-1140
    • Jones, N.G.1    Decamp, A.2    Gilbert, P.3    Peterson, M.L.4    Gurwith, M.5    Cao, H.6
  • 88
    • 0346366982 scopus 로고    scopus 로고
    • + T Cells to an HIV-1 Antigen through a Prime Boost Regimen with Heterologous E1-Deleted Adenoviral Vaccine Carriers
    • Pinto, A. R., Fitzgerald, J. C., Giles-Davis, W., Gao, G. P., Wilson, J. M., Ertl, H. C. (2003) Induction of CD8+ T cells to an HIV-1 antigen through a prime boost regimen with heterologous E1-deleted adenoviral vaccine carriers. J. Immunol. 171, 6774-6779. (Pubitemid 37532111)
    • (2003) Journal of Immunology , vol.171 , Issue.12 , pp. 6774-6779
    • Pinto, A.R.1    Fitzgerald, J.C.2    Giles-Davis, W.3    Gao, G.P.4    Wilson, J.M.5    Ertl, H.C.J.6
  • 96
    • 0030813127 scopus 로고    scopus 로고
    • Outcome of immunization of cynomolgus monkeys with recombinant semliki forest virus encoding human immunodeficiency virus type 1 envelope protein and challenge with a high dose of SHIV-4 virus
    • Berglund, P., Quesada-Rolander, M., Putkonen, P., Biberfeld, G., Thorstensson, R., Liljestrom, P. (1997) Outcome of immunization of cynomolgus monkeys with recombinant Semliki Forest virus encoding human immunodeficiency virus type 1 envelope protein and challenge with a high dose of SHIV-4 virus. AIDS Res. Hum. Retroviruses 13, 1487-1495. (Pubitemid 27500577)
    • (1997) AIDS Research and Human Retroviruses , vol.13 , Issue.17 , pp. 1487-1495
    • Berglund, P.1    Quesada-Rolander, M.2    Putkonen, P.3    Biberfeld, G.4    Thorstensson, R.5    Liljestrom, P.6
  • 98
    • 7044234963 scopus 로고    scopus 로고
    • Use of a Clostridium perfringens vector to express high levels of SIV p27 protein for the development of an oral SIV vaccine
    • DOI 10.1016/j.virol.2004.08.018, PII S004268220400529X
    • Chen, Y., Helmus, R., McClane, B., Hoffman, R., Watkins, S., Wehrli, T., Gupta, P. (2004) Use of a Clostridium perfringens vector to express high levels of SIV p27 protein for the development of an oral SIV vaccine. Virology 329, 226-233. (Pubitemid 39423973)
    • (2004) Virology , vol.329 , Issue.2 , pp. 226-233
    • Chen, Y.1    Helmus, R.2    McClane, B.3    Hoffman, R.4    Watkins, S.5    Wehrli, T.6    Gupta, P.7
  • 99
    • 55249123781 scopus 로고    scopus 로고
    • Recombinant Mycobacterium bovis BCG vector system expressing SIV gag protein stably and persistently induces antigen-specific humoral immune response concomitant with IFN γ response, even at three years after immunization
    • Kawahara, M. (2008) Recombinant Mycobacterium bovis BCG vector system expressing SIV gag protein stably and persistently induces antigen-specific humoral immune response concomitant with IFN γ response, even at three years after immunization. Clin. Immunol. 129, 492-498.
    • (2008) Clin. Immunol. , vol.129 , pp. 492-498
    • Kawahara, M.1
  • 102
    • 33747340247 scopus 로고    scopus 로고
    • Safety and immunogenicity of attenuated Salmonella enterica serovar
    • DOI 10.1016/j.vaccine.2006.05.094, PII S0264410X06006888
    • Kotton, C. N., Lankowski, A. J., Scott, N., Sisul, D., Chen, L. M., Raschke, K., Borders, G., Boaz, M., Spentzou, A., Galan, J. E., Hohmann, E. L. (2006) Safety and immunogenicity of attenuated Salmonella enterica serovar Typhimurium delivering an HIV-1 gag antigen via the Salmonella type III secretion system. Vaccine 24, 6216-6224. (Pubitemid 44247245)
    • (2006) Vaccine , vol.24 , Issue.37-39 , pp. 6216-6224
    • Kotton, C.N.1    Lankowski, A.J.2    Scott, N.3    Sisul, D.4    Chen, L.M.5    Raschke, K.6    Borders, G.7    Boaz, M.8    Spentzou, A.9    Galan, J.E.10    Hohmann, E.L.11
  • 103
    • 0036184412 scopus 로고    scopus 로고
    • + T-cell response to human immunodeficiency virus type 1 Gag and Env generated by vaccination with recombinant vesicular stomatitis viruses
    • DOI 10.1128/JVI.76.6.2730-2738.2002
    • Haglund, K., Leiner, I., Kerksiek, K., Buonocore, L., Pamer, E., Rose, J. K. (2002) High-level primary CD8(+) T-cell response to human immunodeficiency virus type 1 gag and env generated by vaccination with recombinant vesicular stomatitis viruses. J. Virol. 76, 2730-2738. (Pubitemid 34184859)
    • (2002) Journal of Virology , vol.76 , Issue.6 , pp. 2730-2738
    • Haglund, K.1    Leiner, I.2    Kerksiek, K.3    Buonocore, L.4    Pamer, E.5    Rose, J.K.6
  • 108
  • 109
    • 34249930119 scopus 로고    scopus 로고
    • Effect of preexisting immunity to adenovirus human serotype 5 antigens on the immune responses of nonhuman primates to vaccine regimens based on human- Or chimpanzee-derived adenovirus vectors
    • DOI 10.1128/JVI.02497-06
    • McCoy, K., Tatsis, N., Korioth-Schmitz, B., Lasaro, M. O., Hensley, S. E., Lin, S. W., Li, Y., Giles-Davis, W., Cun, A., Zhou, D., Xiang, Z., Letvin, N. L., Ertl, H. C. (2007) Effect of preexisting immunity to adenovirus human serotype 5 antigens on the immune responses of nonhuman primates to vaccine regimens based on human- or chimpanzee-derived adenovirus vectors. J. Virol. 81, 6594-6604. (Pubitemid 46878063)
    • (2007) Journal of Virology , vol.81 , Issue.12 , pp. 6594-6604
    • McCoy, K.1    Tatsis, N.2    Korioth-Schmitz, B.3    Lasaro, M.O.4    Hensley, S.E.5    Lin, S.-W.6    Li, Y.7    Giles-Davis, W.8    Cun, A.9    Zhou, D.10    Xiang, Z.11    Letvin, N.L.12    Ertl, H.C.J.13
  • 111
    • 0036058450 scopus 로고    scopus 로고
    • Insertion of HIV-1 genes into Ad4ΔE3 vector abrogates increased pathogenesis in cotton rats due to E3 deletion
    • DOI 10.1006/viro.2001.1248
    • Patterson, L. J., Prince, G. A., Richardson, E., Alvord, W. G., Kalyan, N., Robert-Guroff, M. (2002) Insertion of HIV-1 genes into Ad4ΔE3 vector abrogates increased pathogenesis in cotton rats due to E3 deletion. Virology 292, 107-113. (Pubitemid 34925843)
    • (2002) Virology , vol.292 , Issue.1 , pp. 107-113
    • Patterson, L.J.1    Prince, G.A.2    Richardson, E.3    Alvord, W.G.4    Kalyan, N.5    Robert-Guroff, M.6
  • 112
    • 33751083817 scopus 로고    scopus 로고
    • DNA vaccines for HIV: Challenges and opportunities
    • DOI 10.1007/s00281-006-0046-z
    • Hokey, D. A., Weiner, D. B. (2006) DNA vaccines for HIV: challenges and opportunities. Springer Semin. Immunopathol. 28, 267-279. (Pubitemid 44764282)
    • (2006) Springer Seminars in Immunopathology , vol.28 , Issue.3 , pp. 267-279
    • Hokey, D.A.1    Weiner, D.B.2
  • 115
    • 43049181912 scopus 로고    scopus 로고
    • Safety and immunogenicity of recombinant low-dosage HIV-1 a vaccine candidates vectored by plasmid pTHr DNA or modified vaccinia virus Ankara (MVA) in humans in East Africa
    • Jaoko, W., Nakwagala, F. N., Anzala, O., Manyonyi, G. O., Birungi, J., Nanvubya, A., Bashir, F., Bhatt, K., Ogutu, H., Wakasiaka, S., et al. (2008) Safety and immunogenicity of recombinant low-dosage HIV-1 A vaccine candidates vectored by plasmid pTHr DNA or modified vaccinia virus Ankara (MVA) in humans in East Africa. Vaccine 26, 2788-2795.
    • (2008) Vaccine , vol.26 , pp. 2788-2795
    • Jaoko, W.1    Nakwagala, F.N.2    Anzala, O.3    Manyonyi, G.O.4    Birungi, J.5    Nanvubya, A.6    Bashir, F.7    Bhatt, K.8    Ogutu, H.9    Wakasiaka, S.10
  • 117
    • 0026484050 scopus 로고
    • Adenovirus-based expression vectors and recombinant vaccines
    • Graham, F. L., Prevec, L. (1992) Adenovirus-based expression vectors and recombinant vaccines. Biotechnology 20, 363-390.
    • (1992) Biotechnology , vol.20 , pp. 363-390
    • Graham, F.L.1    Prevec, L.2
  • 118
    • 0036618178 scopus 로고    scopus 로고
    • Preferential transformation of human neuronal cells by human adenoviruses and the origin of HEK 293 cells
    • Shaw, G., Morse, S., Ararat, M., Graham, F. L. (2002) Preferential transformation of human neuronal cells by human adenoviruses and the origin of HEK 293 cells. FASEB J. 16, 869-871.
    • (2002) FASEB J. , vol.16 , pp. 869-871
    • Shaw, G.1    Morse, S.2    Ararat, M.3    Graham, F.L.4
  • 121
    • 0036147328 scopus 로고    scopus 로고
    • E4orf6 variants with separate abilities to augment adenovirus replication and direct nuclear localization of the E1B 55-kilodalton protein
    • Orlando, J. S., Ornelles, D. A. (2002) E4orf6 variants with separate abilities to augment adenovirus replication and direct nuclear localization of the E1B 55-kilodalton protein. J. Virol. 76, 1475-1487.
    • (2002) J. Virol. , vol.76 , pp. 1475-1487
    • Orlando, J.S.1    Ornelles, D.A.2
  • 125
    • 1542299092 scopus 로고    scopus 로고
    • Recent advances in the development of HIV-1 vaccines using replication-incompetent adenovirus vectors
    • Shiver, J. W., Emini, E. A. (2004) Recent advances in the development of HIV-1 vaccines using replication-incompetent adenovirus vectors. Annu. Rev. Med. 55, 355-372.
    • (2004) Annu. Rev. Med. , vol.55 , pp. 355-372
    • Shiver, J.W.1    Emini, E.A.2
  • 129
    • 0042890357 scopus 로고    scopus 로고
    • Structural and phylogenetic analysis of adenovirus hexons by use of high-resolution X-ray crystallographic, molecular modeling, and sequence-based methods
    • Rux, J. J., Kuser, P. R., Burnett, R. M. (2003) Structural and phylogenetic analysis of adenovirus hexons by use of high-resolution X-ray crystallographic, molecular modeling, and sequence-based methods. J. Virol. 77, 9553-9566.
    • (2003) J. Virol. , vol.77 , pp. 9553-9566
    • Rux, J.J.1    Kuser, P.R.2    Burnett, R.M.3
  • 130
    • 27144508046 scopus 로고    scopus 로고
    • + T cell induction, is dependent on type I IFN signaling during vaccination with adenovirus vectors
    • Hensley, S. E., Giles-Davis, W., McCoy, K. C., Weninger, W., Ertl, H. C. (2005) Dendritic cell maturation, but not CD8+ T cell induction, is dependent on type I IFN signaling during vaccination with adenovirus vectors. J. Immunol. 175, 6032-6041. (Pubitemid 41508089)
    • (2005) Journal of Immunology , vol.175 , Issue.9 , pp. 6032-6041
    • Hensley, S.E.1    Giles-Davis, W.2    McCoy, K.C.3    Weninger, W.4    Ertl, H.C.J.5
  • 131
    • 3142764761 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1-specific immune responses in primates upon sequential immunization with adenoviral vaccine carriers of human and simian serotypes
    • DOI 10.1128/JVI.78.14.7392-7399.2004
    • Reyes-Sandoval, A., Fitzgerald, J. C., Grant, R., Roy, S., Xiang, Z. Q., Li, Y., Gao, G. P., Wilson, J. M., Ertl, H. C. (2004) Human immunodeficiency virus type 1-specific immune responses in primates upon sequential immunization with adenoviral vaccine carriers of human and simian serotypes. J. Virol. 78, 7392-7399. (Pubitemid 38915884)
    • (2004) Journal of Virology , vol.78 , Issue.14 , pp. 7392-7399
    • Reyes-Sandoval, A.1    Fitzgerald, J.C.2    Grant, R.3    Roy, S.4    Xiang, Z.Q.5    Li, Y.6    Gao, G.P.7    Wilson, J.M.8    Ertl, H.C.J.9
  • 132
    • 33845466958 scopus 로고    scopus 로고
    • Immunogenicity of heterologous recombinant adenovirus prime-boost vaccine regimens is enhanced by circumventing vector cross-reactivity
    • DOI 10.1128/JVI.01749-06
    • Thorner, A. R., Lemckert, A. A., Goudsmit, J., Lynch, D. M., Ewald, B. A., Denholtz, M., Havenga, M. J., Barouch, D. H. (2006) Immunogenicity of heterologous recombinant adenovirus prime-boost vaccine regimens is enhanced by circumventing vector cross-reactivity. J. Virol. 80, 12009-12016. (Pubitemid 44904350)
    • (2006) Journal of Virology , vol.80 , Issue.24 , pp. 12009-12016
    • Thorner, A.R.1    Lemckert, A.A.C.2    Goudsmit, J.3    Lynch, D.M.4    Ewald, B.A.5    Denholtz, M.6    Havenga, M.J.E.7    Barouch, D.H.8
  • 135
    • 13944254982 scopus 로고    scopus 로고
    • Placebo-controlled phase 3 trial of a recombinant glycoprotein 120 vaccine to prevent HIV-1 infection
    • Flynn, N. M., Forthal, D. N., Harro, C. D., Judson, F. N., Mayer, K. H., Para, M. F. (2005) Placebo-controlled phase 3 trial of a recombinant glycoprotein 120 vaccine to prevent HIV-1 infection. J. Infect. Dis. 191, 654-665.
    • (2005) J. Infect. Dis. , vol.191 , pp. 654-665
    • Flynn, N.M.1    Forthal, D.N.2    Harro, C.D.3    Judson, F.N.4    Mayer, K.H.5    Para, M.F.6
  • 138
    • 37549037877 scopus 로고    scopus 로고
    • Intradermal/subcutaneous immunization by electroporation improves plasmid vaccine delivery and potency in pigs and rhesus macaques
    • Hirao, L. A., Wu, L., Khan, A. S., Satishchandran, A., Draghia-Akli, R., Weiner, D. B. (2008) Intradermal/subcutaneous immunization by electroporation improves plasmid vaccine delivery and potency in pigs and rhesus macaques. Vaccine 26, 440-448.
    • (2008) Vaccine , vol.26 , pp. 440-448
    • Hirao, L.A.1    Wu, L.2    Khan, A.S.3    Satishchandran, A.4    Draghia-Akli, R.5    Weiner, D.B.6
  • 140
    • 33746192136 scopus 로고    scopus 로고
    • HIV/AIDS preventive vaccine 'prime-boost' phase III trial: Foundations and initial lessons learned from Thailand
    • DOI 10.1097/01.aids.0000237362.26370.f8, PII 0000203020060713000001
    • Rerks-Ngarm, S., Brown, A. E., Khamboonruang, C., Thongcharoen, P., Kunasol, P. (2006) HIV/AIDS preventive vaccine "prime-boost" phase III trial: foundations and initial lessons learned from Thailand. AIDS 20, 1471-1479. (Pubitemid 44100207)
    • (2006) AIDS , vol.20 , Issue.11 , pp. 1471-1479
    • Rerks-Ngarm, S.1    Brown, A.E.2    Khamboonruang, C.3    Thongcharoen, P.4    Kunasol, P.5
  • 141
    • 58149136160 scopus 로고    scopus 로고
    • Post-step modifications for research on HIV vaccines
    • Corey, L., McElrath, M. J., Kublin, J. G. (2009) Post-step modifications for research on HIV vaccines. AIDS 23, 3-8.
    • (2009) AIDS , vol.23 , pp. 3-8
    • Corey, L.1    McElrath, M.J.2    Kublin, J.G.3
  • 152
    • 0029852819 scopus 로고    scopus 로고
    • Increased plasma human immunodeficiency virus type 1 burden following antigenic challenge with pneumococcal vaccine
    • Brichacek, B., Swindells, S., Janoff, E. N., Pirruccello, S., Stevenson, M. (1996) Increased plasma human immunodeficiency virus type 1 burden following antigenic challenge with pneumococcal vaccine. J. Infect. Dis. 174, 1191-1199. (Pubitemid 26393896)
    • (1996) Journal of Infectious Diseases , vol.174 , Issue.6 , pp. 1191-1199
    • Brichacek, B.1    Swindells, S.2    Janoff, E.N.3    Pirruccello, S.4    Stevenson, M.5
  • 154
    • 0034494046 scopus 로고    scopus 로고
    • Effect of influenza vaccination on disease progression among HIV-infected persons
    • Sullivan, P. S., Hanson, D. L., Dworkin, M. S., Jones, J. L., Ward, J. W. (2000) Effect of influenza vaccination on disease progression among HIV-infected persons. AIDS 14, 2781-2785.
    • (2000) AIDS , vol.14 , pp. 2781-2785
    • Sullivan, P.S.1    Hanson, D.L.2    Dworkin, M.S.3    Jones, J.L.4    Ward, J.W.5
  • 158
    • 0014122647 scopus 로고
    • Active immunization of rats with a cell-free extract of the erythrocytic parasites of Plasmodium berghei
    • Zuckerman, A., Hamburger, Y., Spira, D. (1967) Active immunization of rats with a cell-free extract of the erythrocytic parasites of Plasmodium berghei. Exp. Parasitol. 21, 84-97.
    • (1967) Exp. Parasitol. , vol.21 , pp. 84-97
    • Zuckerman, A.1    Hamburger, Y.2    Spira, D.3


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