CCR5 or CXCR4 use influences the relationship between CD4 cell depletion, NKp44L expression and NK cytotoxicity in SHIV-infected macaques

AIDS

Volumn 22, Issue 2, 2008, Pages 185-192

  Vieillard, Vincent ^a,e   Habib, Raphaelle El ^b   Brochard, Patricia ^c,d   Delache, Benoit ^c,d   Bovendo, Hugues Fausther ^a   Calvo, Julien ^c,d   Morin, Julie ^c,d   Picq, Isabelle ^c,d   Martinon, Frédéric ^c,d   Vaslin, Bruno ^c,d   Le Grand, Roger ^c,d   Debré, Patrice ^a  

^a ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^b SANOFI PASTEUR   (France)

^c INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE   (France)

^d UNIVERSITÉ PARIS SACLAY   (France)

^e PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

Anti 3S gp41 antibody; CCR5 and CXCR4 viral tropisms; Macaque model; Natural killer (NK) cells; NKp44 ligand; SHIV

Indexed keywords

CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; GLYCOPROTEIN GP 41; LIGAND; NKP44 LIGAND; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY PRODUCTION; ARTICLE; CD4 LYMPHOCYTE COUNT; CELL ACTIVITY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME LINKED IMMUNOSPOT ASSAY; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MACACA; NATURAL KILLER T CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MOTIF; VIROGENESIS; VIRUS LOAD;

AMINO ACID MOTIFS; ANIMALS; ANTIBODIES, VIRAL; CD4 LYMPHOCYTE COUNT; CD4-POSITIVE T-LYMPHOCYTES; CYTOTOXICITY TESTS, IMMUNOLOGIC; HIV ENVELOPE PROTEIN GP41; KILLER CELLS, NATURAL; MACACA FASCICULARIS; REASSORTANT VIRUSES; RECEPTORS, CCR4; RECEPTORS, CCR5; RECEPTORS, CXCR4; RECEPTORS, IMMUNOLOGIC; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 37549044238     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/QAD.0b013e3282f35551     Document Type: Article

References (29)

1. Grossman Z, Meier-Schellersheim M, Sousa AE, Victorino RM, Paul WE. CD4+ T-cell depletion in HIV infection: are we closer to understanding the cause? Nat Med 2002; 8:319-323.
2. Alimonti JB, Ball TB, Fowke KR. Mechanisms of CD4+ T lymphocyte cell death in human immunodeficiency virus infection and AIDS. J Gen Virol 2003; 84:1649-1661.
3. Gougeon ML. Apoptosis as an HIV strategy to escape immune attack. Nat Rev Immunol 2003; 3:392-404.
4. Derdeyn CA, Silvestri G. Viral and host factors in the pathogenesis of HIV infection. Curr Opin Immunol 2005; 17:366-373.
5. Vieillard V, Strominger JL, Debre P. NK cytotoxicity against CD4+ T cells during HIV-1 infection: a gp41 peptide induces the expression of an NKp44 ligand. Proc Natl Acad Sci U S A 2005; 102:10981-10986.
6. Ward J, Bonaparte M, Sacks J, Guterman J, Fogli M, Mavilio D. NK HIV modulates the expression of ligands important in triggering natural killer cell cy. Blood 2007 In press.
7. Vieillard V, Costagliola D, Simon A, Debre P, French Asymptomatiques a Long Terme (ALT) Study Group. Specific adaptive humoral response against a gp41 motif inhibits CD4 T-cell sensitivity to NK lysis during HIV-1 infection. AIDS 2006; 20:1795-1804.
8. Fauci AS, Mavilio D, Kottilil S. NK cells in HIV infection: paradigm for protection or targets for ambush. Nat Rev Immunol 2005; 5:835-843.
9. Alter G, Altfeld M. NK cell function in HIV-1 infection. Curr Mol Med 2006; 6:621-629.
10. Reimann KA, Li JT, Veazey R, Halloran M, Park IW, Karlsson GB, et al. A chimeric simian/human immunodeficiency virus expressing a primary patient human immunodeficiency virus type 1 isolate env causes an AIDS-like disease after in vivo passage in rhesus monkeys. J Virol 1996; 70:6922-6928.
11. Harouse JM, Gettie A, Eshetu T, Tan RC, Bohm R, Blanchard J, et al. Mucosal transmission and induction of simian AIDS by CCR5-specific simian/human immunodeficiency virus SHIV (SF162P3). J Virol 2001; 75:1990-1995.
12. Aubertin AM, Le Grand R, Wang Y, Beyer C, Tao L, Neildez O, et al. Generation of CD8+ T cell-generated suppressor factor and beta-chemokines by targeted iliac lymph node immunization in rhesus monkeys challenged with SHIV-89.6P by the rectal route. AIDS Res Hum Retroviruses 2000; 16:381-392.
13. Hofmann-Lehmann R, Vlasak J, Williams AL, Chenine AL, McClure HM, Anderson DC, et al. Live attenuated, nef-deleted SIV is pathogenic in most adult macaques after prolonged observation. AIDS 2003; 17:157-166.
14. Davenport MP, Zhang L, Shiver JW, Casmiro DR, Ribeiro RM, Perelson AS. Influence of peak viral load on the extent of CD4+ T-cell depletion in simian HIV infection. J Acquir Immune Defic Syndr 2006; 41:259-265.
15. Theodorou I, Meyer L, Magierowska M, Katlama C, Rouzioux C. HIV-1 infection in an individual homozygous for CCR5 delta 32. Seroco Study Group. Lancet 1997; 349: 1219-1220.
16. Davenport MP, Zaunders JJ, Hazenberg MD, Schuitemaker H, van Rij RP. Cell turnover and cell tropism in HIV-1 infection. Trends Microbiol 2002; 10:275-278.
17. Tersmette M, Lange JM, de Goede RE, de Wolf F, Eeftink-Schattenkerk JK, Schellekens PT, et al. Association between biological properties of human immunodeficiency virus variants and risk for AIDS and AIDS mortality. Lancet 1989; 1:983-985.
18. Scarlatti G, Tresoldi E, Bjorndal A, Fredriksson R, Colognesi C, Deng HK, et al. In vivo evolution of HIV-1 co-receptor usage and sensitivity to chemokine-mediated suppression. Nat Med 1997; 3:1259-1265.
19. Connor RI, Sheridan KE, Ceradini D, Choe S, Landau NR. Change in coreceptor use coreceptor use correlates with disease progression in HIV-1-infected individuals. J Exp Med 1997; 185:621-628.
20. Shankarappa R, Margolick JB, Gange SJ, Rodrigo AG, Upchurch D, Farzadegan H, et al. Consistent viral evolutionary changes associated with the progression of human immunodeficiency virus type 1 infection. J Virol 1999; 73: 10489-10502.
21. Watson A, Ranchalis J, Travis B, McClure J, Sutton W, Johnson PR, et al. Plasma viremia in macaques infected with simian immunodeficiency virus: plasma viral load early in infection predicts survival. J Virol 1997; 71:284-290.
22. Regoes RR, Staprans SI, Feinberg MB, Bonhoeffer S. Contribution of peaks of virus load to simian immunodeficiency virus pathogenesis. J Virol 2002; 76:2573-2578.
23. Autran B, Carcelain G, Combadiere B, Debre P. Therapeutic vaccines for chronic infections. Science 2004; 305:205-208.
24. Benito JM, López M, Soriano V. The role of CD8+ T-cell response in HIV infection. AIDS Rev 2004; 6:79-88.
25. Scott-Algara D, Truong LX, Versmisse P, David A, Luong TT, Nguyen NV, et al. Cutting edge: increased NK cell activity in HIV-1-exposed but uninfected Vietnamese intravascular drug users. J Immunol 2003; 171:5663-5667.
26. Bruunsgaard H, Pedersen C, Skinhoj P, Pedersen BK. Clinical progression of HIV infection: role of NK cells. Scand J Immunol 1997; 46:91-95.
27. Ironson G, Balbin E, Solomon G, Fahey J, Klimas N, Schneiderman N, Fletcher MA. Relative preservation of natural killer cell cytotoxicity and number in healthy AIDS patients with low CD4 cell counts. AIDS 2001; 15:2065-2673.
28. Martin MP, Qi Y, Gao X, Yamada E, Martin JN, Pereyra F, et al. Innate partnership of HLA-B and KIR3DL1 subtypes against HIV-1. Nat Gen 2007; 39:733-740.
29. Bonaparte MI, Barker E. Inability of natural killer cells to destroy autologous HIV-infected T lymphocytes. AIDS 2003; 17:487-494.