Chronic increases in sphingosine kinase-1 activity induce a pro-inflammatory, pro-angiogenic phenotype in endothelial cells

Cellular and Molecular Biology Letters

Volumn 14, Issue 3, 2009, Pages 424-441

  Limaye, Vidya ^a,b,c   Xia, Pu ^e   Hahn, Chris ^b   Smith, Malcolm ^d   Vadas, Mathew A ^e   Pitson, Stuart M ^b,c   Gamble, Jennifer R ^e  

^a ROYAL ADELAIDE HOSPITAL   (Australia)

^b INSTITUTE OF MEDICAL AND VETERINARY SCIENCE   (Australia)

^c UNIVERSITY OF ADELAIDE   (Australia)

^d REPATRIATION GENERAL HOSPITAL   (Australia)

^e UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Angiogenesis; Endothelial cells; Inflammation; Sphingosine kinase; TNF

Indexed keywords

CYTOKINE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; SPHINGOSINE KINASE 1; TUMOR NECROSIS FACTOR; VASCULAR CELL ADHESION MOLECULE 1; DRUG DERIVATIVE; LYSOPHOSPHOLIPID; PHOSPHOTRANSFERASE; SPHINGOSINE; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1-PHOSPHATE; SPHINGOSINE KINASE; TUMOR NECROSIS FACTOR ALPHA;

ADHESION; ANGIOGENESIS; ARTICLE; CELL ACTIVATION; CELL ADHESION; CELL FUNCTION; CELL MIGRATION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; HUMAN; HUMAN CELL; INFLAMMATION; NEUTROPHIL; OSTEOARTHRITIS; PROTEIN EXPRESSION; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; SYNOVIAL FLUID LEVEL; UMBILICAL VEIN; VECTOR CONTROL; CELL MOTION; CHRONIC DISEASE; CYTOLOGY; ENZYMOLOGY; METABOLISM; PHENOTYPE; VASCULAR ENDOTHELIUM;

ARTHRITIS, RHEUMATOID; CELL ADHESION; CELL MOVEMENT; CHRONIC DISEASE; E-SELECTIN; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; HUMANS; LYSOPHOSPHOLIPIDS; NEOVASCULARIZATION, PHYSIOLOGIC; OSTEOARTHRITIS; PHENOTYPE; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); SIGNAL TRANSDUCTION; SPHINGOSINE; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR CELL ADHESION MOLECULE-1;

EID: 70349573285     PISSN: 14258153     EISSN: 16891392     Source Type: Journal    
DOI: 10.2478/s11658-009-0009-1     Document Type: Article

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