Chromosome 5q deletion and epigenetic suppression of the gene encoding α-catenin (CTNNA1) in myeloid cell transformation

Nature Medicine

Volumn 13, Issue 1, 2007, Pages 78-83

  Liu, Ting Xi ^a,b   Becker, Michael W ^c   Jelinek, Jaroslav ^d   Wu, Wen Shu ^b   Deng, Min ^a,b   Mikhalkevich, Natallia ^c   Hsu, Karl ^b   Bloomfield, Clara D ^e,f   Stone, Richard M ^b   DeAngelo, Daniel J ^b   Galinsky, Ilene A ^b   Issa, Jean Pierre ^d   Clarke, Michael F ^g   Look, A Thomas ^b  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF ROCHESTER   (United States)

^d UNIVERSITY OF TEXAS   (United States)

^e OHIO STATE UNIVERSITY   (United States)

^f UNIVERSITY OF CHICAGO   (United States)

^g STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CATENIN;

ACUTE GRANULOCYTIC LEUKEMIA; ALLELE; APOPTOSIS; ARTICLE; BONE MARROW CELL; CELL PROLIFERATION; CELL TRANSFORMATION; CHROMOSOME 5Q; CHROMOSOME DELETION; CONTROLLED STUDY; CTNNA1 GENE; DEACETYLATION; EPIGENETICS; GENE; GENE EXPRESSION REGULATION; GENE MUTATION; GENE REPRESSION; GENE SEQUENCE; GENETIC VARIABILITY; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; METHYLATION; MUTATIONAL ANALYSIS; MYELODYSPLASTIC SYNDROME; PRIORITY JOURNAL; PROMOTER REGION;

ACUTE DISEASE; ALPHA CATENIN; BLOTTING, WESTERN; CELL LINE; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 5; DNA METHYLATION; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; GREEN FLUORESCENT PROTEINS; HL-60 CELLS; HUMANS; HYDROXAMIC ACIDS; IN SITU HYBRIDIZATION, FLUORESCENCE; K562 CELLS; LEUKEMIA, MYELOID; MUTATION; MYELODYSPLASTIC SYNDROMES; MYELOID PROGENITOR CELLS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSFECTION; U937 CELLS;

EID: 33846113924     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm1512     Document Type: Article

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