GATA-3: An unexpected regulator of cell lineage determination in skin

Genes and Development

Volumn 17, Issue 17, 2003, Pages 2108-2122

  Kaufman, Charles K ^a,b   Zhou, Ping ^b   Pasolli, H Amalia ^a   Rendl, Michael ^a   Bolotin, Diana ^a   Lim, Kim Chew ^c   Dai, Xing ^d   Alegre, Maria Luisa ^b   Fuchs, Elaine ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

GATA 3; Hair follicle development; IRS; Matrix; TGF s; Wnts

Indexed keywords

BETA GALACTOSIDASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 3; WNT PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL LINEAGE; CELL SPECIFICITY; CYTOLOGY; DNA MICROARRAY; EMBRYO; EPIDERMIS; HAIR; HAIR CELL; HAIR FOLLICLE; HAIR GROWTH; HAIR ROOT; LYMPHOCYTE DIFFERENTIATION; MORPHOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN APPENDAGE; SKIN CELL; SKIN GRAFT; STEM CELL; TRANSCRIPTION REGULATION;

ANIMALS; CELL DIFFERENTIATION; DNA-BINDING PROTEINS; GATA3 TRANSCRIPTION FACTOR; HAIR FOLLICLE; MICE; SKIN; SKIN TRANSPLANTATION; TRANS-ACTIVATORS;

ANIMALIA; STAPHYLOCOCCUS PHAGE 3A;

EID: 0041319629     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.1115203     Document Type: Article

References (61)

1. Byrne, C., Tainsky, M., and Fuchs, E. 1994. Programming gene expression in developing epidermis. Development 120: 2369-2383.
2. Cachon-Gonzalez, M.B., Fenner, S., Coffin, J.M., Moran, C., Best, S., and Stoye, J.P. 1994. Structure and expression of the hairless gene of mice. Proc. Natl. Acad. Sci. 91: 7717-7721.
3. Cantor, A.B. and Orkin, S.H. 2002. Transcriptional regulation of erythropoiesis: An affair involving multiple partners. Oncogene 21: 3368-3376.
4. Carlsson, P., Waterman, M.L., and Jones, K.A. 1993. The hLEF/TCF-1 α. HMG protein contains a context-dependent transcriptional activation domain that induces the TCR α enhancer in T cells. Genes & Dev. 7: 2418-2430.
5. Chan, E.F., Gat, U., McNiff, J.M., and Fuchs, E. 1999. A common human skin tumour is caused by activating mutations in α-catenin. Nat. Genet. 21: 410-413.
6. Conlon, R.A. and Rossant, J. 1992. Exogenous retinoic acid rapidly induces anterior ectopic expression of murine Hox-2 genes in vivo. Development 116: 357-368.
7. Cotsarelis, G., Sun, T.T., and Lavker, R.M. 1990. Label-retaining cells reside in the bulge area of pilosebaceous unit: Implications for follicular stem cells, hair cycle, and skin carcinogenesis. Cell 61: 1329-1337.
8. Dai, X., Schonbaum, C., Degenstein, L., Bai, W., Mahowald, A., and Fuchs, E. 1998. The ovo gene required for cuticle formation and oogenesis in flies is involved in hair formation and spermatogenesis in mice. Genes & Dev. 12: 3452-3463.
9. DasGupta, R. and Fuchs, E. 1999. Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation. Development 126: 4557-4568.
10. Dry, F.W. 1926. The coat of the mouse (Mus musculum). J. Genet. 16: 287-340.
11. Ellis, T., Gambardella, L., Horcher, M., Tschanz, S., Capol, J., Bertram, P., Jochum, W., Barrandon, Y., and Busslinger, M. 2001. The transcriptional repressor CDP (Cutl1) is essential for epithelial cell differentiation of the lung and the hair follicle. Genes & Dev. 15: 2307-2319.
12. Flanagan, S.P. 1966. 'Nude,' a new hairless gene with pleiotropic effects in the mouse. Genet. Res. 8: 295-309.
13. Fuchs, E., Merrill, B.J., Jamora, C., and DasGupta, R. 2001. At the roots of a never-ending cycle. Dev. Cell 1: 13-25.
14. Fuiiwara, T., Dehart, D.B., Sulik, K.K., and Hogan, B.L. 2002. Distinct requirements for extra-embryonic and embryonic bone morphogenetic protein 4 in the formation of the node and primitive streak and coordination of left-right asymmetry in the mouse. Development 129: 4685-4696.
15. Gambardella, L., Schneider-Maunoury, S., Voiculescu, O., Charnay, P., and Barrandon, Y. 2000. Pattern of expression of the transcription factor Krox-20 in mouse hair follicle. Mech. Dev. 96: 215-218.
16. Gat, U., DasGupta, R., Degenstein, L., and Fuchs, E. 1998. De novo hair follicle morphogenesis and hair tumors in mice expressing a truncated α-catenin in skin. Cell 95: 605-614.
17. Giese, K. and Grosschedl, R. 1993. LEF-1 contains an activation domain that stimulates transcription only in a specific context of factor-binding sites. EMBO J. 12: 4667-4676.
18. Hardman, M.J., Sisi, P., Banbury, D.N., and Byrne, C. 1998. Patterned acquisition of skin barrier function during development. Development 125: 1541-1552.
19. Hardy, M.H. 1992. The secret life of the hair follicle. Trends Genet. 8: 55-61.
20. Hattori, N., Kawamoto, H., Fujimoto, S., Kuno, K., and Katsura, Y. 1996. Involvement of transcription factors TCF-1 and GATA-3 in the initiation of the earliest step of T cell development in the thymus. J. Exp. Med. 184: 1137-1147.
21. Hendriks, R.W., Nawijn, M.C., Engel, J.D., van Doorninck, H., Grosveld, F., and Karis, A. 1999. Expression of the transcription factor GATA-3 is required for the development of the earliest T cell progenitors and correlates with stages of cellular proliferation in the thymus. Eur. J. Immunol. 29: 1912-1918.
22. Kuo, C.T. and Leiden, J.M. 1999. Transcriptional regulation of T lymphocyte development and function. Annu. Rev. Immunol. 17: 149-187.
23. Kurata, H., Lee, H.J., McClanahan, T., Coffman, R.L., O'Garra, A., and Arai, N. 2002. Friend of GATA is expressed in naive Th cells and functions as a repressor of GATA-3-mediated Th2 cell development. J. Immunol. 168: 4538-4545.
24. Lakshmanan, G., Lieuw, K.H., Lim, K.C., Gu, Y., Grosveld, F., Engel, J.D., and Karis, A. 1999. Localization of distant urogenital system-, central nervous system-, and endocardium-specific transcriptional regulatory elements in the GATA-3 locus. Mol. Cell. Biol. 19: 1558-1568.
25. Langbein, L., Rogers, M.A., Praetzel, S., Winter, H., and Schweizer, J. 2003. K6irs1, K6irs2, K6irs3, and K6irs4 represent the inner-root-sheath-specific type II epithelial keratins of the human hair follicle. J. Invest. Dermatol. 120: 512-522.
26. Lee, D., Prowse, D.M., and Brissette, J.L. 1999. Association between mouse nude gene expression and the initiation of epithelial terminal differentiation. Dev. Biol. 208: 362-374.
27. Li, M., Indra, A.K., Warot, X., Brocard, J., Messaddeq, N., Kato, S., Metzger, D., and Chambon, P. 2000. Skin abnormalities generated by temporally controlled RXRα mutations in mouse epidermis. Nature 407: 633-636.
28. Lim, K.C., Lakshmanan, G., Crawford, S.E., Gu, Y., Grosveld, F., and Engel, J.D. 2000. Gata3 loss leads to embryonic lethality due to noradrenaline deficiency of the sympathetic nervous system. Nat. Genet. 25: 209-212.
29. Lynch, M.H., O'Guin, W.M., Hardy, C., Mak, L., and Sun, T.T. 1986. Acidic and basic hair/nail ("hard") keratins: Their colocalization in upper cortical and cuticle cells of the human hair follicle and their relationship to "soft" keratins. J. Cell Biol. 103: 2593-2606.
30. Ma, L., Liu, J., Wu, T., Plikus, M., Jiang, T.X., Bi, Q., Liu, Y.H., Muller-Rover, S., Peters, H., Sundberg, J.P., et al. 2003. 'Cyclic alopecia' in Msx2 mutants: Defects in hair cycling and hair shaft differentiation. Development 130: 379-389.
31. Mill, P., Mo, R., Fu, H., Grachtchouk, M., Kim, P.C., Dlugosz, A.A., and Hui, C.C. 2003. Sonic hedgehog-dependent activation of Gli2 is essential for embryonic hair follicle development. Genes & Dev. 17: 282-294.
32. Millar, S.E. 2002. Molecular mechanisms regulating hair follicle development. J. Invest. Dermatol. 118: 216-225.
33. Nehls, M., Pfeifer, D., Schorpp, M., Hedrich, H., and Boehm, T. 1994. New member of the winged-helix protein family disrupted in mouse and rat nude mutations. Nature 372: 103-107.
34. Niemann, C. and Watt, F.M. 2002. Designer skin: Lineage commitment in postnatal epidermis. Trends Cell Biol. 12: 185-192.
35. O'Guin, W.M., Sun, T.T., and Manabe, M. 1992. Interaction of trichohyalin with intermediate filaments: Three immunologically defined stages of trichohyalin maturation. J. Invest. Dermatol. 98: 24-32.
36. Okamura, R.M., Sigvardsson, M., Galceran, J., Verbeek, S., Clevers, H., and Grosschedl, R. 1998. Redundant regulation of T cell differentiation and TCRα. gene expression by the transcription factors LEF-1 and TCF-1. Immunity 8: 11-20.
37. Oliver, R.F. and Jahoda, C.A. 1988. Dermal-epidermal interactions. Clin. Dermatol. 6: 74-82.
38. Oosterwegel, M., Timmerman, J., Leiden, J., and Clevers, H. 1992. Expression of GATA-3 during lymphocyte differentiation and mouse embryogenesis. Dev. Immunol. 3: 1-11.
39. Oshima, H., Rochat, A., Kedzia, C., Kobayashi, K., and Barrandon, Y. 2001. Morphogenesis and renewal of hair follicles from adult multipotent stem cells. Cell 104: 233-245.
40. Ouyang, W., Lohning, M., Gao, Z., Assenmacher, M., Ranganath, S., Radbruch, A., and Murphy, K.M. 2000. Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment. Immunity 12: 27-37.
41. Pandolfi, P.P., Roth, M.E., Karis, A., Leonard, M.W., Dzierzak, E., Grosveld, F.G., Engel, J.D., and Lindenbaum, M.H. 1995. Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis. Nat. Genet. 11: 40-44.
42. Panteleyev, A.A., Paus, R., and Christiano, A.M. 2000. Patterns of hairless (hr) gene expression in mouse hair follicle morphogenesis and cycling. Am. J. Pathol. 157: 1071-1079.
43. Panteleyev, A.A., Jahoda, C.A., and Christiano, A.M. 2001. Hair follicle predetermination. J. Cell Sci. 114: 3419-3431.
44. Patient, R.K. and McGhee, J.D. 2002. The GATA family (vertebrates and invertebrates). Curr. Opin. Genet. Dev. 12: 416-422.
45. Pennisi, D., Bowles, J., Nagy, A., Muscat, G., and Koopman, P. 2000. Mice-null for sox18 are viable and display a mild coat defect. Mol. Cell. Biol. 20: 9331-9336.
46. Robins, E.J. and Breathnach, A.S. 1970. Fine structure of bulbar end of human foetal hair follicle at stage of differentiation of inner root sheath. J. Anat. 107: 131-146.
47. Schaeren-Wiemers, N. and Gerfin-Moser, A. 1993. A single protocol to detect transcripts of various types and expression levels in neural tissue and cultured cells: In situ hybridization using digoxigenin-labelled cRNA probes. Histochemistry 100: 431-440.
48. Schilham, M.W., Wilson, A., Moerer, P., Benaissa-Trouw, B.J., Cumano, A., and Clevers, H.C. 1998. Critical involvement of Tcf-1 in expansion of thymocytes. J. Immunol. 161: 3984-3991.
49. Segre, J.A., Nemhauser, J.L., Taylor, B.A., Nadeau, J.H., and Lander, E.S. 1995. Positional cloning of the nude locus: Genetic, physical, and transcription maps of the region and mutations in the mouse and rat. Genomics 28: 549-559.
50. Segre, J.A., Bauer, C., and Fuchs, E. 1999. Klf4 is a transcription factor required for establishing the barrier function of the skin. Nat. Genet. 22: 356-360.
51. Taylor, G., Lehrer, M.S., Jensen, P.J., Sun, T.T., and Lavker, R.M. 2000. Involvement of follicular stem cells in forming not only the follicle but also the epidermis. Cell 102: 451-461.
52. Ting, C.N., Olson, M.C., Barton, K.P., and Leiden, J.M. 1996. Transcription factor GATA-3 is required for development of the T-cell lineage. Nature 384: 474-478.
53. Tsang, A.P., Visvader, J.E., Turner, C.A., Fujiwara, Y., Yu, C., Weiss, M.J., Crossley, M., and Orkin, S.H. 1997. FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation. Cell 90: 109-119.
54. van Doorninck, J.H., van Der Wees, J., Karis, A., Goedknegt, E., Engel, J.D., Coesmans, M., Rutteman, M., Grosveld, F., and De Zeeuw, C.I. 1999. GATA-3 is involved in the development of serotonergic neurons in the caudal raphe nuclei. J. Neurosci. 19: RC12.
55. van Genderen, C., Okamura, R.M., Farinas, I., Quo, R.G., Parslow, T.G., Bruhn, L., and Grosschedl, R. 1994. Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice. Genes & Dev. 8: 2691-2703.
56. Verbeek, S., Izon, D., Hofhuis, F., Robanus-Maandag, E., te Riele, H., van de Wetering, M., Oosterwegel, M., Wilson, A., MacDonald, H.R., and Clevers, H. 1995. An HMG-box-containing T-cell factor required for thymocyte differentiation. Nature 374: 70-74.
57. Winter, H., Langbein, L., Praetzel, S., Jacobs, M., Rogers, M.A., Leigh, I.M., Tidman, N., and Schweizer, J. 1998. A novel human type II cytokeratin, K6hf, specifically expressed in the companion layer of the hair follicle. J. Invest. Dermatol. 111: 955-962.
58. Zhang, D.H., Cohn, L., Ray, P., Bottomly, K., and Ray, A. 1997. Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 gene. J. Biol. Chem. 272: 21597-21603.
59. Zheng, W. and Flavell, R.A. 1997. The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell 89: 587-596.
60. Zhou, M., Ouyang, W., Gong, Q., Katz, S.G., White, J.M., Orkin, S.H., and Murphy, K.M. 2001. Friend of GATA-1 represses GATA-3-dependent activity in CD4+ T cells. J. Exp. Med. 194: 1461-1471.
61. Zhou, P., Byrne, C., Jacobs, J., and Fuchs, E. 1995. Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fate. Genes & Dev. 9: 700-713.