Production of a recombinant mouse monoclonal antibody in transgenic silkworm cocoons

FEBS Journal

Volumn 276, Issue 20, 2009, Pages 5806-5820

  Iizuka, Masashi ^a   Ogawa, Shingo ^b   Takeuchi, Atsushi ^a   Nakakita, Shinichi ^c   Kubo, Yuhki ^d   Miyawaki, Yoshitaka ^d   Hirabayashi, Jun ^c   Tomita, Masahiro ^a  

^a Higashihiroshima   (Japan)

^b Koken Co Ltd   (Japan)

^c KAGAWA UNIVERSITY   (Japan)

^d Masuda Chemical Industries Co Ltd   (Japan)

Author keywords

IgG; Monoclonal antibody; N glycosylation; Recombinant protein; Silk gland

Indexed keywords

COMPLEMENTARY DNA; FUCOSE; GLYCOPEPTIDASE; GLYCOPROTEIN; IMMUNOGLOBULIN G; MANNOSE; MESSENGER RNA; MONOCLONAL ANTIBODY; N ACETYLGLUCOSAMINE; PAUCIMANNOSE; PROTEIN G; RECOMBINANT ANTIBODY; SERICIN; SERICIN 1; UNCLASSIFIED DRUG;

ANTIBODY PRODUCTION; ANTIGEN BINDING; ARTICLE; BACULOVIRUS; COCOON; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; EXTRACTION; FUCOSYLATION; GENE EXPRESSION; HYBRIDOMA; IMMUNOGLOBULIN PRODUCTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PURIFICATION; SILKWORM; STRUCTURE ANALYSIS; SYNTHESIS; TISSUE SPECIFICITY; TRANSGENE; TRANSGENIC ORGANISM;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANTIBODIES, ANTI-IDIOTYPIC; ANTIBODIES, MONOCLONAL; BOMBYX; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; MICE; PROMOTER REGIONS, GENETIC; RECOMBINANT FUSION PROTEINS; SERICINS; SILK; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

BOMBYX MORI; HEXAPODA;

EID: 70349522023     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2009.07262.x     Document Type: Article

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