Identification and characterisation of the novel amyloid-beta peptide-induced protein p17

FEBS Letters

Volumn 583, Issue 19, 2009, Pages 3247-3253

  Nehar, Saheen ^a   Mishra, Manisha ^a   Heese, Klaus ^a  

^a NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

Alzheimer's disease; Amyloid; BDNF; Neurotrophin; TrkB

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; COMPLEMENTARY DNA; PROTEIN KINASE C; PROTEIN P17;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL LINE; CONTROLLED STUDY; DNA DETERMINATION; DOWNSTREAM PROCESSING; HUMAN; HUMAN CELL; HUMAN TISSUE; MOUSE; NEUROTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; SIGNAL TRANSDUCTION; UPREGULATION;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN; ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL LINE, TUMOR; DISEASE MODELS, ANIMAL; HUMANS; MICE; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; RATS; TISSUE DISTRIBUTION;

EID: 70349464654     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2009.09.018     Document Type: Article

References (32)

1. Nagy Z. The last neuronal division: a unifying hypothesis for the pathogenesis of Alzheimer's disease. J. Cell. Mol. Med. 9 (2005) 531-541
2. Hardy J., and Selkoe D.J. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 297 (2002) 353-356
3. Selkoe D.J. Cell biology of the amyloid beta-protein precursor and the mechanism of Alzheimer's disease. Annu. Rev. Cell Biol. 10 (1994) 373-403
4. Heininger K. A unifying hypothesis of Alzheimer's disease. II. Pathophysiological processes. Hum. Psychopharmacol. Clin. Exp. 14 (1999) 555-581
5. Gschwind M., and Huber G. Apoptotic cell death induced by beta-amyloid 1-42 peptide is cell type dependent. J. Neurochem. 65 (1995) 292-300
6. Toullec D., et al. The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C. J. Biol. Chem. 266 (1991) 15771-15781
7. Heese K., Nagai Y., and Sawada T. Identification of a new synaptic vesicle protein 2B mRNA transcript which is up-regulated in neurons by amyloid beta peptide fragment (1-42). Biochem. Biophys. Res. Commun. 289 (2001) 924-928
8. Yokota T., et al. Brain site-specific gene expression analysis in Alzheimer's disease patients. Eur. J. Clin. Invest. 36 (2006) 820-830
9. Heese K., Otten U., Mathivet P., Raiteri M., Marescaux C., and Bernasconi R. GABA(B) receptor antagonists elevate both mRNA and protein levels of the neurotrophins nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) but not neurotrophin-3 (NT-3) in brain and spinal cord of rats. Neuropharmacology 39 (2000) 449-462
10. Schubert D., et al. Clonal cell lines from the rat central nervous system. Nature 249 (1974) 224-227
11. Bottenstein J.E., and Sato G.H. Growth of a rat neuroblastoma cell line in serum-free supplemented medium. Proc. Natl. Acad. Sci. USA 76 (1979) 514-517
12. Kaplan D.R., Matsumoto K., Lucarelli E., and Thiele C.J. Induction of TrkB by retinoic acid mediates biologic responsiveness to BDNF and differentiation of human neuroblastoma cells. Eukaryotic Signal Transduction Group. Neuron 11 (1993) 321-331
13. Encinas M., Iglesias M., Liu Y., Wang H., Muhaisen A., Cena V., Gallego C., and Comella J.X. Sequential treatment of SH-SY5Y cells with retinoic acid and brain-derived neurotrophic factor gives rise to fully differentiated, neurotrophic factor-dependent, human neuron-like cells. J. Neurochem. 75 (2000) 991-1003
14. Heese K., Yamada T., Akatsu H., Yamamoto T., Kosaka K., Nagai Y., and Sawada T. Characterizing the new transcription regulator protein p60TRP. J. Cell. Biochem. 91 (2004) 1030-1042
15. Islam O., Gong X., Rose-John S., and Heese K. Interleukin-6 and neural stem cells: more than gliogenesis. Mol. Biol. Cell 20 (2009) 188-199
16. Lacroix M., et al. Gene regulation by phorbol 12-myristate 13-acetate in MCF-7 and MDA-MB-231, two breast cancer cell lines exhibiting highly different phenotypes. Oncol. Rep. 12 (2004) 701-707
17. Platet N., Prevostel C., Derocq D., Joubert D., Rochefort H., and Garcia M. Breast cancer cell invasiveness: correlation with protein kinase C activity and differential regulation by phorbol ester in estrogen receptor-positive and -negative cells. Int. J. Cancer 75 (1998) 750-756
18. Mucke L., et al. High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation. J. Neurosci. 20 (2000) 4050-4058
19. Ting J.T., Kelley B.G., Lambert T.J., Cook D.G., and Sullivan J.M. Amyloid precursor protein overexpression depresses excitatory transmission through both presynaptic and postsynaptic mechanisms. Proc. Natl. Acad. Sci. USA 104 (2007) 353-358
20. Tong L., Balazs R., Thornton P.L., and Cotman C.W. Beta-amyloid peptide at sublethal concentrations downregulates brain-derived neurotrophic factor functions in cultured cortical neurons. J. Neurosci. 24 (2004) 6799-6809
21. Hock C., Heese K., Hulette C., Rosenberg C., and Otten U. Region-specific neurotrophin imbalances in Alzheimer disease: decreased levels of brain-derived neurotrophic factor and increased levels of nerve growth factor in hippocampus and cortical areas. Arch. Neurol. 57 (2000) 846-851
22. Hock C.H., Heese K., Olivieri G., Hulette C.H., Rosenberg C., Nitsch R.M., and Otten U. Alterations in neurotrophins and neurotrophin receptors in Alzheimer's disease. J. Neural. Transm. Suppl. 59 (2000) 171-174
23. Yamada K., and Nabeshima T. Brain-derived neurotrophic factor/TrkB signaling in memory processes. J. Pharmacol. Sci. 91 (2003) 267-270
24. Magrane J., Rosen K.M., Smith R.C., Walsh K., Gouras G.K., and Querfurth H.W. Intraneuronal beta-amyloid expression downregulates the Akt survival pathway and blunts the stress response. J. Neurosci. 25 (2005) 10960-10969
25. Hetman M., Kanning K., Cavanaugh J.E., and Xia Z. Neuroprotection by brain-derived neurotrophic factor is mediated by extracellular signal-regulated kinase and phosphatidylinositol 3-kinase. J. Biol. Chem. 274 (1999) 22569-22580
26. Deng X., Gao F., Flagg T., and May Jr. W.S. Mono- and multisite phosphorylation enhances Bcl2's antiapoptotic function and inhibition of cell cycle entry functions. Proc. Natl. Acad. Sci. USA 101 (2004) 153-158
27. Yamamoto K., Ichijo H., and Korsmeyer S.J. BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M. Mol. Cell. Biol. 19 (1999) 8469-8478
28. Haldar S., Jena N., and Croce C.M. Inactivation of Bcl-2 by phosphorylation. Proc. Natl. Acad. Sci. USA 92 (1995) 4507-4511
29. De Chiara G., et al. Bcl-2 phosphorylation by p38 MAPK: identification of target sites and biologic consequences. J. Biol. Chem. 281 (2006) 21353-21361
30. Tanaka C., and Nishizuka Y. The protein kinase C family for neuronal signaling. Annu. Rev. Neurosci. 17 (1994) 551-567
31. Hung A.Y., Haass C., Nitsch R.M., Qiu W.Q., Citron M., Wurtman R.J., Growdon J.H., and Selkoe D.J. Activation of protein kinase C inhibits cellular production of the amyloid beta-protein. J. Biol. Chem. 268 (1993) 22959-22962
32. Annaert W., and De Strooper B. A cell biological perspective on Alzheimer's disease. Annu. Rev. Cell Dev. Biol. 18 (2002) 25-51