Breast cancer cell invasiveness: Correlation with protein kinase C activity and differential regulation by phorbol ester in estrogen receptor- positive and -negative cells

International Journal of Cancer

Volumn 75, Issue 5, 1998, Pages 750-756

  Platet, Nadine ^a   Prévostel, Corinne ^a   Derocq, Danielle ^a   Joubert, Dominique ^a   Rochefort, Henri ^a   Garcia, Marcel ^a  

^a INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR; PHORBOL ESTER; PROTEIN KINASE C;

ARTICLE; BREAST CARCINOGENESIS; BREAST CARCINOMA; CANCER CELL CULTURE; CANCER INVASION; CELL MOTILITY; CELL SPREADING; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; METASTASIS POTENTIAL; MICROTUBULE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

BREAST NEOPLASMS; CARCINOMA; CHEMOTAXIS; COLLAGEN; DRUG COMBINATIONS; FEMALE; HUMANS; LAMININ; NEOPLASM INVASIVENESS; PROTEIN KINASE C; PROTEOGLYCANS; RECEPTORS, ESTROGEN; TETRADECANOYLPHORBOL ACETATE; TUMOR CELLS, CULTURED;

EID: 2642684554     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19980302)75:5<750::AID-IJC14>3.0.CO;2-A     Document Type: Article

References (26)

1. ALBINI, A., IWAMOTO, Y., KLEINMAN, H.K., MARTIN, G.R., AARONSON, S.A., KOZLOWSKI, J.M. and MCEWAN, R.N., A rapid in vitro assay for quantitating the invasion potential of tumor cells. Cancer Res., 47, 3239-3245 (1987).
2. ALVARO, V., LÉVY, L., DUBRAY, C., ROCHE, A., PHILLON, F., QUÉRAT, B. and JOUBERT, D., Invasive human pituitary tumors express a point mutated a protein kinase C. J. clin. Endocrinol. Metab., 77, 1125-1129 (1993).
3. ALVARO, V., TOURAINE, P., RAISMAN VOZARI, R., BAI-GRENIER, F., BIRMAN, P. and JOUBERT, D., Protein kinase C activity and expression in normal and adenomatous human pituitaries. Int. J. Cancer, 50, 724-730 (1992).
4. BLOBE, G.C., OBEID, L.M. and HANNUN, Y.A., Regulation of protein kinase C and role in cancer biology. Cancer Metastasis Rev., 13, 411-431 (1994).
5. BLOBE, G.G., SACHS, C.W., KHAN, W.A., FABBRO, D., STABEL, S., WETSEL, W.C., OBEID, L.M., FINE, R.L. and HANNUN, Y.A., Selective regulation of expression of protein kinase C (PKC) isoenzymes in multidrug-resistant MCF-7 cells. Functional significance of enhanced expression of PKC alpha. J. biol. Chem., 268, 658-664 (1993).
6. 2+ -dependent protein kinase of human mammary carcinoma cells: inverse relationship to estrogen receptors. Int. J. Cancer, 40, 344-348 (1987).
7. DEKKER, L.V. and PARKER, P.J., Protein-kinase C-α question of specificity. Trends biochem. Sci., 19, 73-77 (1994).
8. GARCIA, M., DEROCQ, D., FREISS, G. and ROCHEFORT, H., Activation of estrogen receptor transfected into a receptor-negative breast cancer cell line decreases the metastatic and invasive potential of the cells. Proc. nat. Acad. Sci. (Wash.), 89, 11538-11542 (1992).
9. HÄHNEL, R. and GSCHWENDT, M., The interaction between protein kinase C (PKC) and estrogens. Int. J. Oncol., 7, 11-16 (1995).
10. HARRINGTON, E.O., LOFFLER, J., NELSON, P.R., KENT, K.C., SIMONS, M. and WARE, J.A., Enhancement of migration by protein kinase Cα and inhibition of proliferation and cell cycle progression by protein kinase Cδ in capillary endothelial cells. J. biol. Chem., 272, 7390-7397 (1997).
11. HARTWIG, J.H., THELEN, M., ROSEN, A., JANMEY, P.A., NAIRN, A.C. and ADEREM, A., MARCKS is an actin filament crosslinking protein regulated by protein kinase C and calcium-calmodulin. Nature (Lond.), 356, 618-622 (1992).
12. HIDAKA, H., INAGAKI, M., KAWAMOTO, S. and SASAKI, Y., Isoquinolinesulfonamides. novel and potent inhibitors of cyclic nucleotide dependent protein kinase and protein kinase C. Biochemistry, 23, 5036-5041 (1984).
13. JAKEN, S. and KILEY, S.C., Protein kinase C: interactions and consequences. Trends Cell Biol. 4, 223-227 (1994).
14. KENNEDY, M.J., PRESTIGIACOMO, L.J., TYLER, G., STRATFORD, MAY, W. and DAVIDSON, N.E., Differential effects of bryostatin 1 and phorbol ester on human breast cancer cell lines. Cancer Res., 52, 1278-1283 (1992).
15. 2+ mobilization and protein kinase C activation in the induction of spontaneous metastasis by mouse mammary adenocarcinoma cells. Cancer Res., 49, 2597-2602 (1989).
16. MANNI, A., BUKWALTER, E., ETINDI, R., KUNSELMAN, S., ROSSINI, A., MAUGER, D., DABBS, D. and DEMERS, L., Induction of a less aggressive breast cancer phenotype by protein kinase C-α and -β overexpression. Cell Growth Differ., 7, 1187-1198 (1996).
17. NISHIZUKA, Y., Protein kinase C and lipid signaling for sustained cellular responses. FASEB J., 9, 484-496 (1995).
18. O'BRIAN, C.A., VOGEL, V.G., SINGLETARY, S.E. and WARD, N.E., Elevated protein kinase C expression in human breast tumor biopsies relative to normal breast tissue. Cancer Res., 49, 3215-3217 (1989).
19. PRÉVOSTEL, C., ALVARO, V., DE BOISVILLIERS, F., MARTIN, A., JAFFIOL, C. and JOUBERT, D., The natural protein kinase Ca mutant is present in human thyroid neoplasms. Oncogene, 11, 669-674 (1995).
20. SAITO, N., KIKKAWA, U., NISHIZUKA, Y. and TANAKA, C., Distribution of protein kinase C like immunoreactive neurons in rat brain. J Neurosci., 8, 369-382 (1988).
21. SEYNAEVE, C.M., STETLER-STEVENSON, M., SEBERS, S., KAUR, G., SAUSVILLE, E.A., and WORLAND, P.J., Cell cycle arrest and growth inhibition by the protein kinase antagonist UCN-01 in human breast carcinoma cells. Cancer Res., 53, 2081-2086 (1993).
22. SHEIKH, M.S., GARCIA, M., PUJOL, P., FONTANA, J.A. and ROCHEFORT, H., Why are estrogen-receptor-negative breast cancers more aggressive than the estrogen-receptor-positive breast cancers? lnvasion Metastasis, 14, 329-336 (1995).
23. TAMM, I., CARDINALE, I. and SEHGAL, P.B., lnterleukin-6 and 12-otetradecanoyl phorbol-13-acetate act synergistically in inducing cell-cell separation and migration of human breast carcinoma cells. Cytokine, 3, 212-223 (1991).
24. THELEN, M., ROSEN, A., NAIRN, A.C. and ADEREM, A., Regulation by phosphorylation of reversible association of a myristoylated protein kinase C substrate with the plasma membrane. Nature (Lond.), 351, 320-322 (1991).
25. VALETTE, A., GAS, N., JOZAN, S., ROUBINET, F., DUPONT, M.A. and BAYARD, F., Influence of 12-O-tetradecanoylphorbol-13-acetate on proliferation and maturation of human breast carcinoma cells (MCF7): relationship to cell cycle events. Cancer Res., 47, 1615-1620 (1987).
26. WAYS, D.K., KUKOLY, C.A., DEVENTE, J., HOOKER, J.L., BRYANT, W.O., POSEKANY, K.J., FLETCHER, D.J., COOK, P.P. and PARKER, P.J., MCF-7 breast cancer cells transfected with protein kinase C-α exhibit altered expression of other protein kinase C isoforms and display a more aggressive neoplastic phenotype. J. clin. Invest., 95, 1906-1915 (1995).