메뉴 건너뛰기




Volumn 15, Issue 1, 2007, Pages 103-109

Molecular genetic analysis of the human dihydrofolate reductase gene: Relation with plasma total homocysteine, serum and red blood cell folate levels

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROFOLATE REDUCTASE; FOLIC ACID; HOMOCYSTEINE;

EID: 33845531853     PISSN: 10184813     EISSN: 14765438     Source Type: Journal    
DOI: 10.1038/sj.ejhg.5201713     Document Type: Article
Times cited : (49)

References (28)
  • 1
    • 0037370532 scopus 로고    scopus 로고
    • Biomarkers of nutrient exposure and status in onecarbon (methyl) metabolism
    • Mason JB: Biomarkers of nutrient exposure and status in onecarbon (methyl) metabolism. J Nutr 2003; 133 (Suppl 3): 941S-947S.
    • (2003) J Nutr , vol.133 , Issue.SUPPL. 3
    • Mason, J.B.1
  • 2
    • 21744441067 scopus 로고    scopus 로고
    • Dietary determinants of plasma homocysteine concentrations
    • Verhoef P, de Groot LC: Dietary determinants of plasma homocysteine concentrations. Semin Vasc Med 2005; 5: 110-123.
    • (2005) Semin Vasc Med , vol.5 , pp. 110-123
    • Verhoef, P.1    de Groot, L.C.2
  • 3
    • 0030979178 scopus 로고    scopus 로고
    • Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: Implications for cancer and neuronal damage
    • Blount BC, Mack MM, Wehr CM et al: Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: Implications for cancer and neuronal damage. Proc Natl Acad Sci USA 1997; 94: 3290-3295.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 3290-3295
    • Blount, B.C.1    Mack, M.M.2    Wehr, C.M.3
  • 5
    • 14044252841 scopus 로고    scopus 로고
    • Gene-nutrient interactions in one-carbon metabolism
    • Friso S, Choi SW: Gene-nutrient interactions in one-carbon metabolism. Curr Drug Metab 2005; 6: 37-46.
    • (2005) Curr Drug Metab , vol.6 , pp. 37-46
    • Friso, S.1    Choi, S.W.2
  • 6
    • 0027080461 scopus 로고
    • Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation
    • Czeizel AE, Dudas I: Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation. N Engl J Med 1992; 327: 1832-1835.
    • (1992) N Engl J Med , vol.327 , pp. 1832-1835
    • Czeizel, A.E.1    Dudas, I.2
  • 7
    • 0037164375 scopus 로고    scopus 로고
    • Homocysteine and cardiovascular disease: Evidence on causality from a meta-analysis
    • Wald DS, Law M, Morris JK: Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis. BW 2002; 325: 1202.
    • (2002) BMJ , vol.325 , pp. 1202
    • Wald, D.S.1    Law, M.2    Morris, J.K.3
  • 8
    • 20444445722 scopus 로고    scopus 로고
    • Homocysteine, MTHFR and risk of venous thrombosis: A meta-analysis of published epidemiological studies
    • den Heijer M, Lewington S, Clarke R: Homocysteine, MTHFR and risk of venous thrombosis: A meta-analysis of published epidemiological studies. J Thromb Haemost 2005; 3: 292-299.
    • (2005) J Thromb Haemost , vol.3 , pp. 292-299
    • den Heijer, M.1    Lewington, S.2    Clarke, R.3
  • 10
    • 0031768425 scopus 로고    scopus 로고
    • Properties of food folates determined by stability and susceptibility to intestinal pteroylpolyglutamate hydrolase action
    • Seyoum E, Selhub J: Properties of food folates determined by stability and susceptibility to intestinal pteroylpolyglutamate hydrolase action. J Nutr 1998; 128: 1956-1960.
    • (1998) J Nutr , vol.128 , pp. 1956-1960
    • Seyoum, E.1    Selhub, J.2
  • 11
    • 0021319887 scopus 로고
    • The functional human dihydrofolate reductase gene
    • Chen MJ, Shimada T, Moulton AD et al: The functional human dihydrofolate reductase gene. J Biol Chem 1984; 259: 3933-3943.
    • (1984) J Biol Chem , vol.259 , pp. 3933-3943
    • Chen, M.J.1    Shimada, T.2    Moulton, A.D.3
  • 12
    • 0020353098 scopus 로고
    • Intronless human dihydrofolate reductase genes are derived from processed RNA molecules
    • Chen W, Shimada T, Moulton AD, Harrison M, Nienhuis AW: Intronless human dihydrofolate reductase genes are derived from processed RNA molecules. Proc Natl Acad Sci USA 1982; 79: 7435-7439.
    • (1982) Proc Natl Acad Sci USA , vol.79 , pp. 7435-7439
    • Chen, W.1    Shimada, T.2    Moulton, A.D.3    Harrison, M.4    Nienhuis, A.W.5
  • 13
    • 0021216769 scopus 로고
    • Chromosomal organization of the human dihydrofolate reductase genes: Dispersion, selective amplification, and a novel form of polymorphism
    • Anagnou NP, O'Brien SJ, Shimada T, Nash WG, Chen MJ, Nienhuis AW: Chromosomal organization of the human dihydrofolate reductase genes: dispersion, selective amplification, and a novel form of polymorphism. Proc Natl Acad Sci USA 1984; 81: 5170-5174.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 5170-5174
    • Anagnou, N.P.1    O'Brien, S.J.2    Shimada, T.3    Nash, W.G.4    Chen, M.J.5    Nienhuis, A.W.6
  • 14
    • 0021659679 scopus 로고
    • Human dihydrofolate reductase gene organization. Extensive conservation of the G+C-Rich 5′ non-coding sequence and strong intron size divergence from homologous mammalian genes
    • Yang JK, Masters JN, Attardi G: Human dihydrofolate reductase gene organization. extensive conservation of the G+C-Rich 5′ non-coding sequence and strong intron size divergence from homologous mammalian genes. J Mol Biol 1984; 176: 169-187.
    • (1984) J Mol Biol , vol.176 , pp. 169-187
    • Yang, J.K.1    Masters, J.N.2    Attardi, G.3
  • 15
    • 0017251735 scopus 로고
    • Dihydrofolate reductase deficiency causing megaloblastic anemia in two families
    • Tauro GP, Danks DM, Rowe PB et al: Dihydrofolate reductase deficiency causing megaloblastic anemia in two families. N Engl J Med 1976; 294: 466-470.
    • (1976) N Engl J Med , vol.294 , pp. 466-470
    • Tauro, G.P.1    Danks, D.M.2    Rowe, P.B.3
  • 16
    • 0016760113 scopus 로고
    • Inborn errors of folate metabolism (second of two parts)
    • Erbe RW: Inborn errors of folate metabolism (second of two parts). N Engl Med 1975; 293: 807-812.
    • (1975) N Engl Med , vol.293 , pp. 807-812
    • Erbe, R.W.1
  • 17
    • 0029433839 scopus 로고
    • Molecular mechanisms of resistance to antifolates, a review
    • Banerjee D, Ercikan-Abali E, Waltham M et al: Molecular mechanisms of resistance to antifolates, a review. Acta Biochim Pol 1995; 42: 457-464.
    • (1995) Acta Biochim Pol , vol.42 , pp. 457-464
    • Banerjee, D.1    Ercikan-Abali, E.2    Waltham, M.3
  • 18
    • 0042914711 scopus 로고    scopus 로고
    • Homocysteine, pharmacogenetics, and neurotoxicity in children with leukemia
    • Yishi S, Griener J, Cheng C et al: Homocysteine, pharmacogenetics, and neurotoxicity in children with leukemia. J Clin Oncol 2003; 21: 3084-3091.
    • (2003) J Clin Oncol , vol.21 , pp. 3084-3091
    • Yishi, S.1    Griener, J.2    Cheng, C.3
  • 20
    • 0942290719 scopus 로고    scopus 로고
    • New 19bp deletion polymorphism in intron-1 of dihydrofolate reductase (DHFR): A risk factor for spina bifida acting in mothers during pregnancy?
    • Johnson WG, Stenroos ES, Spychala JR, Chatkupt S, Ming SX, Buyske S: New 19bp deletion polymorphism in intron-1 of dihydrofolate reductase (DHFR): A risk factor for spina bifida acting in mothers during pregnancy? Am J Med Genet 2004; 124A: 339-345.
    • (2004) Am J Med Genet , vol.124 A , pp. 339-345
    • Johnson, W.G.1    Stenroos, E.S.2    Spychala, J.R.3    Chatkupt, S.4    Ming, S.X.5    Buyske, S.6
  • 21
    • 0028949953 scopus 로고
    • Is hyperhomocysteinaermia a risk factor for recurrent venous thrombosis?
    • den Heijer M, Blom HJ, Gerrits WB et al: Is hyperhomocysteinaermia a risk factor for recurrent venous thrombosis? Lancet 1995; 345: 882-885.
    • (1995) Lancet , vol.345 , pp. 882-885
    • den Heijer, M.1    Blom, H.J.2    Gerrits, W.B.3
  • 22
    • 0024284028 scopus 로고
    • A simple salting out procedure for extracting DNA from human nucleated cells
    • Miller SA, Dykes DD, Polesky HF: A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988; 16: 1215.
    • (1988) Nucleic Acids Res , vol.16 , pp. 1215
    • Miller, S.A.1    Dykes, D.D.2    Polesky, H.F.3
  • 23
    • 0028913608 scopus 로고
    • Three different methods for the determination of total homocysteine in plasma
    • te Poele-Pothoff MT, van den Berg M, Franken DG et al: Three different methods for the determination of total homocysteine in plasma. Ann Clin Biochem 1995; 32: 218-220.
    • (1995) Ann Clin Biochem , vol.32 , pp. 218-220
    • te Poele-Pothoff, M.T.1    van den Berg, M.2    Franken, D.G.3
  • 24
    • 0029122937 scopus 로고
    • Functional analysis and dna polymorphism of the tandemly repeated sequences in the 5′-terminal regulatory region of the human gene for thymidylate synthase
    • Horie N, Aiba H, Oguro K, Hojo H, Takeishi K: Functional analysis and dna polymorphism of the tandemly repeated sequences in the 5′-terminal regulatory region of the human gene for thymidylate synthase. Cell Struct Funct 1995; 20: 191-197.
    • (1995) Cell Struct Funct , vol.20 , pp. 191-197
    • Horie, N.1    Aiba, H.2    Oguro, K.3    Hojo, H.4    Takeishi, K.5
  • 25
    • 0029564716 scopus 로고
    • Nine-bp repeat polymorphism in exon 1 of the HMSH3 gene
    • Nakajima E, Orimo H, Ikejima M, Shimada T: Nine-bp repeat polymorphism in exon 1 of the HMSH3 gene. Jpn J Hum Genet 1995; 40: 343-345.
    • (1995) Jpn J Hum Genet , vol.40 , pp. 343-345
    • Nakajima, E.1    Orimo, H.2    Ikejima, M.3    Shimada, T.4
  • 26
    • 0034771885 scopus 로고    scopus 로고
    • A novel single-nucleotide polymorphism in the 3′-untranslated region of the human dihydrofolate reductase gene with enhanced expression
    • Goto Y, Yue I., Yokoi A et al: A novel single-nucleotide polymorphism in the 3′-untranslated region of the human dihydrofolate reductase gene with enhanced expression. Clin Cancer Res 2001; 7: 1952-1956.
    • (2001) Clin Cancer Res , vol.7 , pp. 1952-1956
    • Goto, Y.1    Yue, I.2    Yokoi, A.3
  • 27
    • 15744388471 scopus 로고    scopus 로고
    • Common dihydrofolate reductase 19-base pair deletion allele: A novel risk factor for pieterm delivery
    • Johnson WG, Scholl TO, Spychala JR, Buyske S, Stenroos ES, Chen X: Common dihydrofolate reductase 19-base pair deletion allele: A novel risk factor for pieterm delivery. Am J Clin Nub, 2005; 81: 664-668.
    • (2005) Am J Clin Nub , vol.81 , pp. 664-668
    • Johnson, W.G.1    Scholl, T.O.2    Spychala, J.R.3    Buyske, S.4    Stenroos, E.S.5    Chen, X.6
  • 28
    • 0020608106 scopus 로고
    • The nucleotide sequence of the CDNA coding for the human dihydrofolic acid reductase
    • Masters JN, Attardi G: The nucleotide sequence of the CDNA coding for the human dihydrofolic acid reductase. Gene 1983; 21: 59-63.
    • (1983) Gene , vol.21 , pp. 59-63
    • Masters, J.N.1    Attardi, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.