-
1
-
-
48249106620
-
Cis-dimerization mediates function of junctional adhesion molecule A
-
Severson E.A., Jiang L., Ivanov A.I., Mandell K.J., Nusrat A., and Parkos C.A. Cis-dimerization mediates function of junctional adhesion molecule A. Mol Biol Cell 19 5 (2008) 1862-1872
-
(2008)
Mol Biol Cell
, vol.19
, Issue.5
, pp. 1862-1872
-
-
Severson, E.A.1
Jiang, L.2
Ivanov, A.I.3
Mandell, K.J.4
Nusrat, A.5
Parkos, C.A.6
-
2
-
-
65249125248
-
Junctional adhesion molecule A (JAM-A) interacts with afadin and PDZ-GEF2 to activate Rap1A, Regulate β1 integrin levels, and enhance cell migration
-
This report connects the function of dimerized JAM-A to interactions with the PDZ domain containing scaffold proteins Afadin and PDZ-GEF2. Data are shown to support how such interactions promote activation of the small G protein Rap1A and stabilize cell surface levels of β1 integrin that ultimately modulates epithelial cell migration.
-
Severson E.A., Lee W.Y., Capaldo C.T., Nusrat A., and Parkos C.A. Junctional adhesion molecule A (JAM-A) interacts with afadin and PDZ-GEF2 to activate Rap1A, Regulate β1 integrin levels, and enhance cell migration. Mol Biol Cell (2009). This report connects the function of dimerized JAM-A to interactions with the PDZ domain containing scaffold proteins Afadin and PDZ-GEF2. Data are shown to support how such interactions promote activation of the small G protein Rap1A and stabilize cell surface levels of β1 integrin that ultimately modulates epithelial cell migration.
-
(2009)
Mol Biol Cell
-
-
Severson, E.A.1
Lee, W.Y.2
Capaldo, C.T.3
Nusrat, A.4
Parkos, C.A.5
-
3
-
-
42049113615
-
Attenuation of junctional adhesion molecule-A is a contributing factor for breast cancer cell invasion
-
Naik M.U., Naik T.U., Suckow A.T., Duncan M.K., and Naik U.P. Attenuation of junctional adhesion molecule-A is a contributing factor for breast cancer cell invasion. Cancer Res 68 7 (2008) 2194-2203
-
(2008)
Cancer Res
, vol.68
, Issue.7
, pp. 2194-2203
-
-
Naik, M.U.1
Naik, T.U.2
Suckow, A.T.3
Duncan, M.K.4
Naik, U.P.5
-
5
-
-
0345991242
-
Essential role of junctional adhesion molecule-1 in basic fibroblast growth factor-induced endothelial cell migration
-
Naik M.U., Vuppalanchi D., and Naik U.P. Essential role of junctional adhesion molecule-1 in basic fibroblast growth factor-induced endothelial cell migration. Arterioscler Thromb Vasc Biol 23 12 (2003) 2165-2171
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, Issue.12
, pp. 2165-2171
-
-
Naik, M.U.1
Vuppalanchi, D.2
Naik, U.P.3
-
6
-
-
0035898658
-
The cell polarity protein ASIP/PAR-3 directly associates with junctional adhesion molecule (JAM)
-
Ebnet K., Suzuki A., Horikoshi Y., Hirose T., Zu M., Brickwedde M.K., Ohno S., and Vestweber D. The cell polarity protein ASIP/PAR-3 directly associates with junctional adhesion molecule (JAM). EMBO J 20 14 (2001) 3738-3748
-
(2001)
EMBO J
, vol.20
, Issue.14
, pp. 3738-3748
-
-
Ebnet, K.1
Suzuki, A.2
Horikoshi, Y.3
Hirose, T.4
Zu, M.5
Brickwedde, M.K.6
Ohno, S.7
Vestweber, D.8
-
7
-
-
2642614521
-
Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration
-
Martin-Padura I., Lostaglio S., Schneemann M., Williams L., Romano M., Fruscella P., Panzeri C., Stoppacciaro A., Ruco L., Villa A., et al. Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration. J Cell Biol 142 1 (1998) 117-127
-
(1998)
J Cell Biol
, vol.142
, Issue.1
, pp. 117-127
-
-
Martin-Padura, I.1
Lostaglio, S.2
Schneemann, M.3
Williams, L.4
Romano, M.5
Fruscella, P.6
Panzeri, C.7
Stoppacciaro, A.8
Ruco, L.9
Villa, A.10
-
8
-
-
15744362477
-
Junctional adhesion molecule 1 regulates epithelial cell morphology through effects on β1 integrins and Rap1 activity
-
Mandell K.J., Babbin B.A., Nusrat A., and Parkos C.A. Junctional adhesion molecule 1 regulates epithelial cell morphology through effects on β1 integrins and Rap1 activity. J Biol Chem 280 12 (2005) 11665-11674
-
(2005)
J Biol Chem
, vol.280
, Issue.12
, pp. 11665-11674
-
-
Mandell, K.J.1
Babbin, B.A.2
Nusrat, A.3
Parkos, C.A.4
-
9
-
-
0033565947
-
Cutting edge: combined treatment of TNF-α and IFN-γ causes redistribution of junctional adhesion molecule in human endothelial cells
-
Ozaki H., Ishii K., Horiuchi H., Arai H., Kawamoto T., Okawa K., Iwamatsu A., and Kita T. Cutting edge: combined treatment of TNF-α and IFN-γ causes redistribution of junctional adhesion molecule in human endothelial cells. J Immunol 163 2 (1999) 553-557
-
(1999)
J Immunol
, vol.163
, Issue.2
, pp. 553-557
-
-
Ozaki, H.1
Ishii, K.2
Horiuchi, H.3
Arai, H.4
Kawamoto, T.5
Okawa, K.6
Iwamatsu, A.7
Kita, T.8
-
10
-
-
37549038994
-
JAM-A regulates permeability and inflammation in the intestine in vivo
-
This is the first study demonstrating that JAM-A deficient mice have increased intestinal epithelial permeability and enhanced susceptibility to experimentally induced colitis. It was shown that the enhanced permeability associated with JAM-A deficiency correlates with altered epithelial claudin expression.
-
Laukoetter M.G., Nava P., Lee W.Y., Severson E.A., Capaldo C.T., Babbin B.A., Williams I.R., Koval M., Peatman E., Campbell J.A., et al. JAM-A regulates permeability and inflammation in the intestine in vivo. J Exp Med 204 13 (2007) 3067-3076. This is the first study demonstrating that JAM-A deficient mice have increased intestinal epithelial permeability and enhanced susceptibility to experimentally induced colitis. It was shown that the enhanced permeability associated with JAM-A deficiency correlates with altered epithelial claudin expression.
-
(2007)
J Exp Med
, vol.204
, Issue.13
, pp. 3067-3076
-
-
Laukoetter, M.G.1
Nava, P.2
Lee, W.Y.3
Severson, E.A.4
Capaldo, C.T.5
Babbin, B.A.6
Williams, I.R.7
Koval, M.8
Peatman, E.9
Campbell, J.A.10
-
11
-
-
33747393306
-
Fibroblast growth factor-2 failed to induce angiogenesis in junctional adhesion molecule-A-deficient mice
-
Cooke V.G., Naik M.U., and Naik U.P. Fibroblast growth factor-2 failed to induce angiogenesis in junctional adhesion molecule-A-deficient mice. Arterioscler Thromb Vasc Biol 26 9 (2006) 2005-2011
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, Issue.9
, pp. 2005-2011
-
-
Cooke, V.G.1
Naik, M.U.2
Naik, U.P.3
-
12
-
-
22244491607
-
JAM-A expression during embryonic development
-
Parris J.J., Cooke V.G., Skarnes W.C., Duncan M.K., and Naik U.P. JAM-A expression during embryonic development. Dev Dyn 233 4 (2005) 1517-1524
-
(2005)
Dev Dyn
, vol.233
, Issue.4
, pp. 1517-1524
-
-
Parris, J.J.1
Cooke, V.G.2
Skarnes, W.C.3
Duncan, M.K.4
Naik, U.P.5
-
13
-
-
38849155809
-
Association of F11 receptor gene polymorphisms with central obesity and blood pressure
-
Ong K.L., Leung R.Y., Wong L.Y., Cherny S.S., Sham P.C., Lam T.H., Lam K.S., and Cheung B.M. Association of F11 receptor gene polymorphisms with central obesity and blood pressure. J Intern Med 263 3 (2008) 322-332
-
(2008)
J Intern Med
, vol.263
, Issue.3
, pp. 322-332
-
-
Ong, K.L.1
Leung, R.Y.2
Wong, L.Y.3
Cherny, S.S.4
Sham, P.C.5
Lam, T.H.6
Lam, K.S.7
Cheung, B.M.8
-
14
-
-
34249323041
-
Junctional adhesion molecule-1 is upregulated in spontaneously hypertensive rats: evidence for a prohypertensive role within the brain stem
-
Waki H., Liu B., Miyake M., Katahira K., Murphy D., Kasparov S., and Paton J.F. Junctional adhesion molecule-1 is upregulated in spontaneously hypertensive rats: evidence for a prohypertensive role within the brain stem. Hypertension 49 6 (2007) 1321-1327
-
(2007)
Hypertension
, vol.49
, Issue.6
, pp. 1321-1327
-
-
Waki, H.1
Liu, B.2
Miyake, M.3
Katahira, K.4
Murphy, D.5
Kasparov, S.6
Paton, J.F.7
-
15
-
-
46049083963
-
Unique role of junctional adhesion molecule-A in maintaining mucosal homeostasis in inflammatory bowel disease
-
This study reported enhanced permeability in the intestinal mucosa of JAM-A knockout mice that is independent of vascular endothelial cells. In addition, it was shown that treatment of wild-type mice with a JAM-A dimerization blocking antibody also results in enhanced intestinal mucosal permeability.
-
Vetrano S., Rescigno M., Rosaria Cera M., Correale C., Rumio C., Doni A., Fantini M., Sturm A., Borroni E., Repici A., Locati M., et al. Unique role of junctional adhesion molecule-A in maintaining mucosal homeostasis in inflammatory bowel disease. Gastroenterology 135 1 (2008) 173-184. This study reported enhanced permeability in the intestinal mucosa of JAM-A knockout mice that is independent of vascular endothelial cells. In addition, it was shown that treatment of wild-type mice with a JAM-A dimerization blocking antibody also results in enhanced intestinal mucosal permeability.
-
(2008)
Gastroenterology
, vol.135
, Issue.1
, pp. 173-184
-
-
Vetrano, S.1
Rescigno, M.2
Rosaria Cera, M.3
Correale, C.4
Rumio, C.5
Doni, A.6
Fantini, M.7
Sturm, A.8
Borroni, E.9
Repici, A.10
Locati, M.11
-
17
-
-
38449112244
-
Junctional adhesion molecules in angiogenesis
-
Naik T.U., Naik M.U., and Naik U.P. Junctional adhesion molecules in angiogenesis. Front Biosci 13 (2008) 258-262
-
(2008)
Front Biosci
, vol.13
, pp. 258-262
-
-
Naik, T.U.1
Naik, M.U.2
Naik, U.P.3
-
18
-
-
34249650761
-
The role of junctional adhesion molecules in vascular inflammation
-
Weber C., Fraemohs L., and Dejana E. The role of junctional adhesion molecules in vascular inflammation. Nat Rev Immunol 7 6 (2007) 467-477
-
(2007)
Nat Rev Immunol
, vol.7
, Issue.6
, pp. 467-477
-
-
Weber, C.1
Fraemohs, L.2
Dejana, E.3
-
19
-
-
61949276292
-
JAM-A promotes neutrophil chemotaxis by controlling integrin internalization and recycling
-
Cera M.R., Fabbri M., Molendini C., Corada M., Orsenigo F., Rehberg M., Reichel C.A., Krombach F., Pardi R., and Dejana E. JAM-A promotes neutrophil chemotaxis by controlling integrin internalization and recycling. J Cell Sci 122 Pt 2 (2009) 268-277
-
(2009)
J Cell Sci
, vol.122
, Issue.PART 2
, pp. 268-277
-
-
Cera, M.R.1
Fabbri, M.2
Molendini, C.3
Corada, M.4
Orsenigo, F.5
Rehberg, M.6
Reichel, C.A.7
Krombach, F.8
Pardi, R.9
Dejana, E.10
-
20
-
-
0035817623
-
Junctional adhesion molecule (JAM) binds to PAR-3: a possible mechanism for the recruitment of PAR-3 to tight junctions
-
Itoh M., Sasaki H., Furuse M., Ozaki H., Kita T., and Tsukita S. Junctional adhesion molecule (JAM) binds to PAR-3: a possible mechanism for the recruitment of PAR-3 to tight junctions. J Cell Biol 154 3 (2001) 491-497
-
(2001)
J Cell Biol
, vol.154
, Issue.3
, pp. 491-497
-
-
Itoh, M.1
Sasaki, H.2
Furuse, M.3
Ozaki, H.4
Kita, T.5
Tsukita, S.6
-
21
-
-
0038185285
-
Crystal structure of human junctional adhesion molecule 1: implications for reovirus binding
-
This study reported the human crystal structure of the extracelluar domain of JAM-A provided a structural basis for the further study of JAM-A function. The structural information provided predicted cis-homodimerization of JAM-A.
-
Prota A.E., Campbell J.A., Schelling P., Forrest J.C., Watson M.J., Peters T.R., Aurrand-Lions M., Imhof B.A., Dermody T.S., and Stehle T. Crystal structure of human junctional adhesion molecule 1: implications for reovirus binding. Proc Natl Acad Sci U S A 100 9 (2003) 5366-5371. This study reported the human crystal structure of the extracelluar domain of JAM-A provided a structural basis for the further study of JAM-A function. The structural information provided predicted cis-homodimerization of JAM-A.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.9
, pp. 5366-5371
-
-
Prota, A.E.1
Campbell, J.A.2
Schelling, P.3
Forrest, J.C.4
Watson, M.J.5
Peters, T.R.6
Aurrand-Lions, M.7
Imhof, B.A.8
Dermody, T.S.9
Stehle, T.10
-
22
-
-
0034623082
-
Junctional adhesion molecule interacts with the PDZ domain-containing proteins AF-6 and ZO-1
-
Ebnet K., Schulz C.U., Meyer Z., Brickwedde M.K., Pendl G.G., and Vestweber D. Junctional adhesion molecule interacts with the PDZ domain-containing proteins AF-6 and ZO-1. J Biol Chem 275 36 (2000) 27979-27988
-
(2000)
J Biol Chem
, vol.275
, Issue.36
, pp. 27979-27988
-
-
Ebnet, K.1
Schulz, C.U.2
Meyer, Z.3
Brickwedde, M.K.4
Pendl, G.G.5
Vestweber, D.6
-
23
-
-
0033902942
-
Human junction adhesion molecule regulates tight junction resealing in epithelia
-
Liu Y., Nusrat A., Schnell F.J., Reaves T.A., Walsh S., Pochet M., and Parkos C.A. Human junction adhesion molecule regulates tight junction resealing in epithelia. J Cell Sci 113 Pt 13 (2000) 2363-2374
-
(2000)
J Cell Sci
, vol.113
, Issue.PART 13
, pp. 2363-2374
-
-
Liu, Y.1
Nusrat, A.2
Schnell, F.J.3
Reaves, T.A.4
Walsh, S.5
Pochet, M.6
Parkos, C.A.7
-
24
-
-
1942501686
-
Involvement of the junctional adhesion molecule-1 (JAM1) homodimer interface in regulation of epithelial barrier function
-
Mandell K.J., McCall I.C., and Parkos C.A. Involvement of the junctional adhesion molecule-1 (JAM1) homodimer interface in regulation of epithelial barrier function. J Biol Chem 279 16 (2004) 16254-16262
-
(2004)
J Biol Chem
, vol.279
, Issue.16
, pp. 16254-16262
-
-
Mandell, K.J.1
McCall, I.C.2
Parkos, C.A.3
-
25
-
-
38549166743
-
Interactions of the cell adhesion molecule nectin with transmembrane and peripheral membrane proteins for pleiotropic functions
-
Rikitake Y., and Takai Y. Interactions of the cell adhesion molecule nectin with transmembrane and peripheral membrane proteins for pleiotropic functions. Cell Mol Life Sci 65 2 (2008) 253-263
-
(2008)
Cell Mol Life Sci
, vol.65
, Issue.2
, pp. 253-263
-
-
Rikitake, Y.1
Takai, Y.2
-
26
-
-
35548932931
-
Nectin and nectin-like molecules: biology and pathology
-
Miyoshi J., and Takai Y. Nectin and nectin-like molecules: biology and pathology. Am J Nephrol 27 6 (2007) 590-604
-
(2007)
Am J Nephrol
, vol.27
, Issue.6
, pp. 590-604
-
-
Miyoshi, J.1
Takai, Y.2
-
27
-
-
14644404265
-
Expression of junctional adhesion molecule-A prevents spontaneous and random motility
-
Bazzoni G., Tonetti P., Manzi L., Cera M.R., Balconi G., and Dejana E. Expression of junctional adhesion molecule-A prevents spontaneous and random motility. J Cell Sci 118 Pt 3 (2005) 623-632
-
(2005)
J Cell Sci
, vol.118
, Issue.PART 3
, pp. 623-632
-
-
Bazzoni, G.1
Tonetti, P.2
Manzi, L.3
Cera, M.R.4
Balconi, G.5
Dejana, E.6
-
28
-
-
0035971241
-
Rap1 is activated by erythropoietin or interleukin-3 and is involved in regulation of beta1 integrin-mediated hematopoietic cell adhesion
-
Arai A., Nosaka Y., Kanda E., Yamamoto K., Miyasaka N., and Miura O. Rap1 is activated by erythropoietin or interleukin-3 and is involved in regulation of beta1 integrin-mediated hematopoietic cell adhesion. J Biol Chem 276 13 (2001) 10453-10462
-
(2001)
J Biol Chem
, vol.276
, Issue.13
, pp. 10453-10462
-
-
Arai, A.1
Nosaka, Y.2
Kanda, E.3
Yamamoto, K.4
Miyasaka, N.5
Miura, O.6
-
29
-
-
58849159701
-
Role of the small GTPase Rap1 for integrin activity regulation in endothelial cells and angiogenesis
-
Carmona G., Gottig S., Orlandi A., Scheele J., Bauerle T., Jugold M., Kiessling F., Henschler R., Zeiher A.M., Dimmeler S., and Chavakis E. Role of the small GTPase Rap1 for integrin activity regulation in endothelial cells and angiogenesis. Blood 113 2 (2009) 488-497
-
(2009)
Blood
, vol.113
, Issue.2
, pp. 488-497
-
-
Carmona, G.1
Gottig, S.2
Orlandi, A.3
Scheele, J.4
Bauerle, T.5
Jugold, M.6
Kiessling, F.7
Henschler, R.8
Zeiher, A.M.9
Dimmeler, S.10
Chavakis, E.11
-
30
-
-
7244242394
-
The cAMP-Epac-Rap1 pathway regulates cell spreading and cell adhesion to laminin-5 through the α3β1 integrin but not the α6β4 integrin
-
Enserink J.M., Price L.S., Methi T., Mahic M., Sonnenberg A., Bos J.L., and Tasken K. The cAMP-Epac-Rap1 pathway regulates cell spreading and cell adhesion to laminin-5 through the α3β1 integrin but not the α6β4 integrin. J Biol Chem 279 43 (2004) 44889-44896
-
(2004)
J Biol Chem
, vol.279
, Issue.43
, pp. 44889-44896
-
-
Enserink, J.M.1
Price, L.S.2
Methi, T.3
Mahic, M.4
Sonnenberg, A.5
Bos, J.L.6
Tasken, K.7
-
31
-
-
0033532074
-
Thermodynamic and kinetic characterization of the interaction between the Ras binding domain of AF6 and members of the Ras subfamily
-
Linnemann T., Geyer M., Jaitner B.K., Block C., Kalbitzer H.R., Wittinghofer A., and Herrmann C. Thermodynamic and kinetic characterization of the interaction between the Ras binding domain of AF6 and members of the Ras subfamily. J Biol Chem 274 19 (1999) 13556-13562
-
(1999)
J Biol Chem
, vol.274
, Issue.19
, pp. 13556-13562
-
-
Linnemann, T.1
Geyer, M.2
Jaitner, B.K.3
Block, C.4
Kalbitzer, H.R.5
Wittinghofer, A.6
Herrmann, C.7
-
32
-
-
0030724368
-
The Ras target AF-6 interacts with ZO-1 and serves as a peripheral component of tight junctions in epithelial cells
-
Yamamoto T., Harada N., Kano K., Taya S., Canaani E., Matsuura Y., Mizoguchi A., Ide C., and Kaibuchi K. The Ras target AF-6 interacts with ZO-1 and serves as a peripheral component of tight junctions in epithelial cells. J Cell Biol 139 3 (1997) 785-795
-
(1997)
J Cell Biol
, vol.139
, Issue.3
, pp. 785-795
-
-
Yamamoto, T.1
Harada, N.2
Kano, K.3
Taya, S.4
Canaani, E.5
Matsuura, Y.6
Mizoguchi, A.7
Ide, C.8
Kaibuchi, K.9
-
34
-
-
0026065140
-
Extracellular matrix-resident basic fibroblast growth factor: implication for the control of angiogenesis
-
Vlodavsky I., Fuks Z., Ishai-Michaeli R., Bashkin P., Levi E., Korner G., Bar-Shavit R., and Klagsbrun M. Extracellular matrix-resident basic fibroblast growth factor: implication for the control of angiogenesis. J Cell Biochem 45 2 (1991) 167-176
-
(1991)
J Cell Biochem
, vol.45
, Issue.2
, pp. 167-176
-
-
Vlodavsky, I.1
Fuks, Z.2
Ishai-Michaeli, R.3
Bashkin, P.4
Levi, E.5
Korner, G.6
Bar-Shavit, R.7
Klagsbrun, M.8
-
35
-
-
0026033307
-
The stimulatory effect of PDGF on vascular smooth muscle cell migration is mediated by the induction of endogenous basic FGF
-
Sato Y., Hamanaka R., Ono J., Kuwano M., Rifkin D.B., and Takaki R. The stimulatory effect of PDGF on vascular smooth muscle cell migration is mediated by the induction of endogenous basic FGF. Biochem Biophys Res Commun 174 3 (1991) 1260-1266
-
(1991)
Biochem Biophys Res Commun
, vol.174
, Issue.3
, pp. 1260-1266
-
-
Sato, Y.1
Hamanaka, R.2
Ono, J.3
Kuwano, M.4
Rifkin, D.B.5
Takaki, R.6
-
36
-
-
36849090838
-
VEGF in biological control
-
Breen E.C. VEGF in biological control. J Cell Biochem 102 6 (2007) 1358-1367
-
(2007)
J Cell Biochem
, vol.102
, Issue.6
, pp. 1358-1367
-
-
Breen, E.C.1
-
37
-
-
40849145557
-
165 induces human aortic smooth muscle cell migration by activating neuropilin-1-VEGFR1-PI3K axis
-
165 induces human aortic smooth muscle cell migration by activating neuropilin-1-VEGFR1-PI3K axis. Biochemistry 47 11 (2008) 3345-3351
-
(2008)
Biochemistry
, vol.47
, Issue.11
, pp. 3345-3351
-
-
Banerjee, S.1
Mehta, S.2
Haque, I.3
Sengupta, K.4
Dhar, K.5
Kambhampati, S.6
Van Veldhuizen, P.J.7
Banerjee, S.K.8
-
38
-
-
21344434097
-
Antibody against junctional adhesion molecule-C inhibits angiogenesis and tumor growth
-
Lamagna C., Hodivala-Dilke K.M., Imhof B.A., and Aurrand-Lions M. Antibody against junctional adhesion molecule-C inhibits angiogenesis and tumor growth. Cancer Res 65 13 (2005) 5703-5710
-
(2005)
Cancer Res
, vol.65
, Issue.13
, pp. 5703-5710
-
-
Lamagna, C.1
Hodivala-Dilke, K.M.2
Imhof, B.A.3
Aurrand-Lions, M.4
-
39
-
-
8444229240
-
The functional interaction of the β2 integrin lymphocyte function-associated antigen-1 with junctional adhesion molecule-A is mediated by the I domain
-
Fraemohs L., Koenen R.R., Ostermann G., Heinemann B., and Weber C. The functional interaction of the β2 integrin lymphocyte function-associated antigen-1 with junctional adhesion molecule-A is mediated by the I domain. J Immunol 173 10 (2004) 6259-6264
-
(2004)
J Immunol
, vol.173
, Issue.10
, pp. 6259-6264
-
-
Fraemohs, L.1
Koenen, R.R.2
Ostermann, G.3
Heinemann, B.4
Weber, C.5
-
40
-
-
58849161367
-
LFA-1 binding destabilizes the JAM-A homophilic interaction during leukocyte transmigration
-
Wojcikiewicz E.P., Koenen R.R., Fraemohs L., Minkiewicz J., Azad H., Weber C., and Moy V.T. LFA-1 binding destabilizes the JAM-A homophilic interaction during leukocyte transmigration. Biophys J 96 1 (2008) 285-293
-
(2008)
Biophys J
, vol.96
, Issue.1
, pp. 285-293
-
-
Wojcikiewicz, E.P.1
Koenen, R.R.2
Fraemohs, L.3
Minkiewicz, J.4
Azad, H.5
Weber, C.6
Moy, V.T.7
-
41
-
-
0035184161
-
Reduced expression of junctional adhesion molecule and platelet/endothelial cell adhesion molecule-1 (CD31) at human vascular endothelial junctions by cytokines tumor necrosis factor-α plus interferon-γ Does not reduce leukocyte transmigration under flow
-
Shaw S.K., Perkins B.N., Lim Y.C., Liu Y., Nusrat A., Schnell F.J., Parkos C.A., and Luscinskas F.W. Reduced expression of junctional adhesion molecule and platelet/endothelial cell adhesion molecule-1 (CD31) at human vascular endothelial junctions by cytokines tumor necrosis factor-α plus interferon-γ Does not reduce leukocyte transmigration under flow. Am J Pathol 159 6 (2001) 2281-2291
-
(2001)
Am J Pathol
, vol.159
, Issue.6
, pp. 2281-2291
-
-
Shaw, S.K.1
Perkins, B.N.2
Lim, Y.C.3
Liu, Y.4
Nusrat, A.5
Schnell, F.J.6
Parkos, C.A.7
Luscinskas, F.W.8
-
42
-
-
19944428045
-
Coordinated redistribution of leukocyte LFA-1 and endothelial cell ICAM-1 accompany neutrophil transmigration
-
Shaw S.K., Ma S., Kim M.B., Rao R.M., Hartman C.U., Froio R.M., Yang L., Jones T., Liu Y., Nusrat A., et al. Coordinated redistribution of leukocyte LFA-1 and endothelial cell ICAM-1 accompany neutrophil transmigration. J Exp Med 200 12 (2004) 1571-1580
-
(2004)
J Exp Med
, vol.200
, Issue.12
, pp. 1571-1580
-
-
Shaw, S.K.1
Ma, S.2
Kim, M.B.3
Rao, R.M.4
Hartman, C.U.5
Froio, R.M.6
Yang, L.7
Jones, T.8
Liu, Y.9
Nusrat, A.10
-
43
-
-
66549086638
-
Regulated release and functional modulation of junctional adhesion molecule A by disintegrin metalloproteinases
-
This study demomnstrates that the extracellular domain of JAM-A is cleaved under inflammatory conditions. It is shown that cleaved JAM-A released under inflammatory conditions can decrease neutrophil transmigration.
-
Koenen R.R., Pruessmeyer J., Soehnlein O., Fraemohs L., Zernecke A., Schwarz N., Reiss K., Sarabi A., Lindbom L., Hackeng T.M., et al. Regulated release and functional modulation of junctional adhesion molecule A by disintegrin metalloproteinases. Blood 113 (2009) 4799-4809. This study demomnstrates that the extracellular domain of JAM-A is cleaved under inflammatory conditions. It is shown that cleaved JAM-A released under inflammatory conditions can decrease neutrophil transmigration.
-
(2009)
Blood
, vol.113
, pp. 4799-4809
-
-
Koenen, R.R.1
Pruessmeyer, J.2
Soehnlein, O.3
Fraemohs, L.4
Zernecke, A.5
Schwarz, N.6
Reiss, K.7
Sarabi, A.8
Lindbom, L.9
Hackeng, T.M.10
-
44
-
-
85047691079
-
Increased DC trafficking to lymph nodes and contact hypersensitivity in junctional adhesion molecule-A-deficient mice
-
Cera M.R., Del Prete A., Vecchi A., Corada M., Martin-Padura I., Motoike T., Tonetti P., Bazzoni G., Vermi W., Gentili F., et al. Increased DC trafficking to lymph nodes and contact hypersensitivity in junctional adhesion molecule-A-deficient mice. J Clin Invest 114 5 (2004) 729-738
-
(2004)
J Clin Invest
, vol.114
, Issue.5
, pp. 729-738
-
-
Cera, M.R.1
Del Prete, A.2
Vecchi, A.3
Corada, M.4
Martin-Padura, I.5
Motoike, T.6
Tonetti, P.7
Bazzoni, G.8
Vermi, W.9
Gentili, F.10
-
45
-
-
17944374159
-
X-ray structure of junctional adhesion molecule: structural basis for homophilic adhesion via a novel dimerization motif
-
Kostrewa D., Brockhaus M., D'Arcy A., Dale G.E., Nelboeck P., Schmid G., Mueller F., Bazzoni G., Dejana E., Bartfai T., et al. X-ray structure of junctional adhesion molecule: structural basis for homophilic adhesion via a novel dimerization motif. EMBO J 20 16 (2001) 4391-4398
-
(2001)
EMBO J
, vol.20
, Issue.16
, pp. 4391-4398
-
-
Kostrewa, D.1
Brockhaus, M.2
D'Arcy, A.3
Dale, G.E.4
Nelboeck, P.5
Schmid, G.6
Mueller, F.7
Bazzoni, G.8
Dejana, E.9
Bartfai, T.10
-
46
-
-
0032547833
-
A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits occludin in fibroblasts
-
Furuse M., Sasaki H., Fujimoto K., and Tsukita S. A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits occludin in fibroblasts. J Cell Biol 143 2 (1998) 391-401
-
(1998)
J Cell Biol
, vol.143
, Issue.2
, pp. 391-401
-
-
Furuse, M.1
Sasaki, H.2
Fujimoto, K.3
Tsukita, S.4
-
47
-
-
33748445496
-
Claudins-key pieces in the tight junction puzzle
-
Koval M. Claudins-key pieces in the tight junction puzzle. Cell Commun Adhes 13 3 (2006) 127-138
-
(2006)
Cell Commun Adhes
, vol.13
, Issue.3
, pp. 127-138
-
-
Koval, M.1
-
48
-
-
33645963995
-
Claudins and epithelial paracellular transport
-
Van Itallie C.M., and Anderson J.M. Claudins and epithelial paracellular transport. Annu Rev Physiol 68 (2006) 403-429
-
(2006)
Annu Rev Physiol
, vol.68
, pp. 403-429
-
-
Van Itallie, C.M.1
Anderson, J.M.2
-
49
-
-
3242705077
-
RhoA, Rac1, and Cdc42 exert distinct effects on epithelial barrier via selective structural and biochemical modulation of junctional proteins and F-actin
-
Bruewer M., Hopkins A.M., Hobert M.E., Nusrat A., and Madara J.L. RhoA, Rac1, and Cdc42 exert distinct effects on epithelial barrier via selective structural and biochemical modulation of junctional proteins and F-actin. Am J Physiol Cell Physiol 287 2 (2004) C327-335
-
(2004)
Am J Physiol Cell Physiol
, vol.287
, Issue.2
-
-
Bruewer, M.1
Hopkins, A.M.2
Hobert, M.E.3
Nusrat, A.4
Madara, J.L.5
-
50
-
-
33745637979
-
Antibody blockade of junctional adhesion molecule-A in rabbit corneal endothelial tight junctions produces corneal swelling
-
Mandell K.J., Holley G.P., Parkos C.A., and Edelhauser H.F. Antibody blockade of junctional adhesion molecule-A in rabbit corneal endothelial tight junctions produces corneal swelling. Invest Ophthalmol Vis Sci 47 6 (2006) 2408-2416
-
(2006)
Invest Ophthalmol Vis Sci
, vol.47
, Issue.6
, pp. 2408-2416
-
-
Mandell, K.J.1
Holley, G.P.2
Parkos, C.A.3
Edelhauser, H.F.4
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