Attenuation of junctional adhesion molecule-A is a contributing factor for breast cancer cell invasion

Cancer Research

Volumn 68, Issue 7, 2008, Pages 2194-2203

  Naik, Meghna U ^a   Naik, Tejal U ^a   Suckow, Arthur T ^a   Duncan, Melinda K ^a   Naik, Ulhas P ^a,b  

^a UNIVERSITY OF DELAWARE   (United States)

^b University of Delaware   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

JUNCTIONAL ADHESION MOLECULE A;

ARTICLE; BREAST CANCER; CANCER CELL; CANCER INVASION; CELL ADHESION; CELL MIGRATION; HUMAN; HUMAN CELL; METASTASIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; TIGHT JUNCTION;

BREAST NEOPLASMS; CELL ADHESION MOLECULES; CELL LINE, TUMOR; CELL MOVEMENT; FOCAL ADHESIONS; HUMANS; IMMUNOGLOBULINS; IMMUNOHISTOCHEMISTRY; NEOPLASM INVASIVENESS; RNA, SMALL INTERFERING; TIGHT JUNCTIONS; TRANSFECTION;

EID: 42049113615     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-07-3057     Document Type: Article

References (49)

1. Dragsten PR, Blumenthal R, Handler JS. Membrane asymmetry in epithelia: is the tight junction a barrier to diffusion in the plasma membrane? Nature 1981;294:718-22.
2. van Meer G, Gumbiner B, Simons K. The tight junction does not allow lipid molecules to diffuse from one epithelial cell to the next. Nature 1986;322:639-41.
3. Fanning AS, Anderson JM. Protein modules as organizers of membrane structure. Curr Opin Cell Biol 1999;11:432-9.
4. Faris M, Ensoli B, Kokot N, Nel AE. Inflammatory cytokines induce the expression of basic fibroblast growth factor (bFGF) isoforms required for the growth of Kaposi's sarcoma and endothelial cells through the activation of AP-1 response elements in the bFGF promoter. AIDS 1998;12:19-27.
5. Matter K, Balda MS. Signalling to and from tight junctions. Nat Rev Mol Cell Biol 2003;4:225-36.
6. Fanning AS, Anderson JM. PDZ domains: fundamental building blocks in the organization of protein complexes at the plasma membrane. J Clin Invest 1999;103:767-72.
7. Furuse M, Fujita K, Hiiragi T, Fujimoto K, Tsukita S. Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin. J Cell Biol 1998;141:1539-50.
8. Gonzalez-Mariscal L, Lechuga S, Garay E. Role of tight junctions in cell proliferation and cancer. Prog Histochem Cytochem 2007;42:1-57.
9. Mandell KJ, Babbin BA, Nusrat A, Parkos CA. Junctional adhesion molecule 1 regulates epithelial cell morphology through effects on β1 integrins and Rap1 activity. J Biol Chem 2005;280:11665-74.
10. Sommers CL, Gelmann EP, Kemler R, Cowin P, Byers SW. Alterations in β-catenin phosphorylation and plakoglobin expression in human breast cancer cells. Cancer Res 1994;54:3544-52.
11. Sommers CL, Thompson EW, Torri JA, Kemler R, Gelmann EP, Byers, SW. Cell adhesion molecule uvomorulin expression in human breast cancer cell lines: relationship to morphology and invasive capacities. Cell Growth Differ 1991;2:365-72.
12. Nieman MT, Kim JB, Johnson KR, Wheelock MJ. Mechanism of extracellular domain-deleted dominant negative cadherins. J Cell Sci 1999;112:1621-32.
13. Nieman MT, Prudoff RS, Johnson KR, Wheelock MJ. N-cadherin promotes motility in human breast cancer cells regardless of their E-cadherin expression. J Cell Biol 1999;147:631-44.
14. Martin-Padura I, Lostaglio S, Schneemann M, et al. Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration. J Cell Biol 1998;142:117-27.
15. Naik UP, Eckfeld K. Junctional adhesion molecule 1 (JAM-1). J Biol Regul Homeostatic Agents 2003;17:341-7.
16. Santoso S, Orlova VV, Song K, Sachs UJ, Andrei-Selme CL, Chavakis T. The homophilic binding of junctional adhesion molecule-C mediates tumor cell-endothelial cell interactions. J Biol Chem 2005;280:36326-33.
17. Bazzoni G. The JAM family of junctional adhesion molecules. Curr Opin Cell Biol 2003;15:525-30.
18. Ebnet K, Suzuki A, Ohno S, Vestweber D. Junctional adhesion molecules (JAMs): more molecules with dual functions? J Cell Sci 2004;117:19-29.
19. Hirabayashi S, Tajima M, Yao I, Nishimura W, Mori H, Hata Y. JAM4, a junctional cell adhesion molecule interacting with a tight junction protein, MAGI-1. Mol Cell Biol 2003;23:4267-82.
20. Moog-Lutz C, Cave-Riant F, Guibal FC, et al. JAML, a novel protein with characteristics of a junctional adhesion molecule, is induced during differentiation of myeloid leukemia cells. Blood 2003;102:3371-8.
21. Zen K, Liu Y, McCall IC, et al. Neutrophil migration across tight junctions is mediated by adhesive interactions between epithelial coxsackie and adenovirus receptor and a junctional adhesion molecule-like protein on neutrophils. Mol Biol Cell 2005;16:2694-703.
22. Naik MU, Mousa SA, Parkos CA, Naik UP. Signaling through JAM-1 and αvβ3 is required for the angiogenic action of bFGF: dissociation of the JAM-1 and αvβ3 complex. Blood 2003;102:2108-14.
23. Ebnet K, Schulz CU, Meyer Zu Brickwedde MK, Pendl GG, Vestweber D. Junctional adhesion molecule (JAM) interacts with the PDZ domain containing proteins AF-6 and ZO-1. J Biol Chem 2000;275:27979-88.
24. Bazzoni G, Martinez-Estrada OM, Orsenigo F, Cordenonsi M, Citi S, Dejana E. Interaction of junctional adhesion molecule with the tight junction components ZO-1, cingulin, and occludin. J Biol Chem 2000;275:20520-6.
25. Kostrewa D, Brockhaus M, D'Arcy A, et al. X-ray structure of junctional adhesion molecule: structural basis for homophilic adhesion via a novel dimerization motif. EMBO J 2001;20:4391-8.
26. Williams LA, Martin-Padura I, Dejana E, Hogg N, Simmons DL. Identification and characterisation of human Junctional Adhesion Molecule (JAM). Mol Immunol 1999;36:1175-88.
27. Naik UP, Naik MU, Eckfeld K, Martin-DeLeon P, Spychala J. Characterization and chromosomal localization of JAM-1, a platelet receptor for a stimulatory monoclonal antibody. J Cell Sci 2001;114:539-47.
28. Soler AP, Miller RD, Laughlin KV, Carp NZ, Klurfeld DM, Mullin JM. Increased tight junctional permeability is associated with the development of colon cancer. Carcinogenesis 1999;20:1425-31.
29. Cui W, Ning J, Naik UP, Duncan MK. OptiRNAi, an RNAi design tool. Comput Methods Programs Biomed 2004;75:67-73.
30. Naik MU, Vuppalanchi D, Naik UP. Essential role of junctional adhesion molecule-1 in basic fibroblast growth factor-induced endothelial cell migration. Arterioscler Thromb Vasc Biol 2003;23:2165-71.
31. Naik UP, Naik MU. Association of CIB with GPIIb/IIIa during outside-in signaling is required for platelet spreading on fibrinogen. Blood 2003;102:1355-62.
32. Naik MU, Naik UP. Junctional adhesion molecule-A-induced endothelial cell migration on vitronectin is integrin αvβ3 specific. J Cell Sci 2006;119:490-9.
33. Thompson EW, Paik S, Brunner N, et al. Association of increased basement membrane invasiveness with absence of estrogen receptor and expression of vimentin in human breast cancer cell lines. J Cell Physiol 1992;150:534-44.
34. Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100:57-70.
35. Konopka G, Tekiela J, Iverson M, Wells C, Duncan SA. Junctional adhesion molecule-A is critical for the formation of pseudocanaliculi and modulates E-cadherin expression in hepatic cells. J Biol Chem 2007;282:28137-48.
36. Yano T, Hernandez-Blazquez FJ, Omori Y, Yamasaki H. Reduction of malignant phenotype of HEPG2 cell is associated with the expression of connexin 26 but not connexin 32. Carcinogenesis 2001;22:1593-600.
37. Martin TA, Watkins G, Mansel RE, Jiang WG. Hepatocyte growth factor disrupts tight junctions in human breast cancer cells. Cell Biol Int 2004;28:361-71.
38. Balda MS, Matter K. Tight junctions. J Cell Sci 1998;111:541-7.
39. Balda MS, Matter K. Transmembrane proteins of tight junctions. Semin Cell Dev Biol 2000;11:281-9.
40. Bazzoni G. Endothelial tight junctions: permeable barriers of the vessel wall. Thromb Haemost 2006;95:36-42.
41. Dejana E, Corada M, Lampugnani MG. Endothelial cell-to-cell junctions. FASEB J 1995;9:910-8.
42. Gumbiner BM. Regulation of cadherin adhesive activity. J Cell Biol 2000;148:399-404.
43. Ozaki H, Ishii K, Horiuchi H, et al. Cutting edge: combined treatment of TNF-α and IFN-γ causes redistribution of junctional adhesion molecule in human endothelial cells. J Immunol 1999;163:553-7.
44. Shaw SK, Perkins BN, Lim YC, et al. Reduced expression of junctional adhesion molecule and platelet/endothelial cell adhesion molecule-1 (CD31) at human vascular endothelial junctions by cytokines tumor necrosis factor-α plus interferon-γ does not reduce leukocyte transmigration under flow. Am J Pathol 2001;159:2281-91.
45. Santibanez JF, Quintanilla M, Martinez J. TGF-β ([1]) and Smad4 overexpression induce a less invasive phenotype in highly invasive spindle carcinoma cells. FEBS Lett 2002;520:171-6.
46. Lee JM, Dedhar S, Kalluri R, Thompson EW. The epithelial-mesenchymal transition: new insights in signaling, development, and disease. J Cell Biol 2006;172:973-81.
47. Bazzoni G, Martinez-Estrada OM, Mueller F, et al. Homophilic interaction of junctional adhesion molecule. J Biol Chem 2000;275:30970-6.
48. Ostermann G, Weber KS, Zernecke A, Schroder A, Weber C. JAM-1 is a ligand of the β2 integrin LFA-1 involved in transendothelial migration of leukocytes. Nat Immunol 2002;3:151-8.
49. Cooke VG, Naik MU, Naik UP. Fibroblast growth factor-2 failed to induce angiogenesis in junctional adhesion molecule-A-deficient mice. Arterioscler Thromb Vasc Biol 2006;26:2005-11.