-
3
-
-
2942642383
-
In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes
-
DOI 10.1084/jem.20040139
-
Tang, Q., K. J. Henriksen, M. Bi, E. B. Finger, G. Szot, J. Ye, E. L. Masteller, H. McDevitt, M. Bonyhadi, and J. A. Bluestone. 2004. In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes. J. Exp. Med. 199: 1455-1465. (Pubitemid 38780401)
-
(2004)
Journal of Experimental Medicine
, vol.199
, Issue.11
, pp. 1455-1465
-
-
Tang, Q.1
Henriksen, K.J.2
Bi, M.3
Finger, E.B.4
Szot, G.5
Ye, J.6
Masteller, E.L.7
McDevitt, H.8
Bonyhadi, M.9
Bluestone, J.A.10
-
4
-
-
22244448391
-
+ regulatory T cells
-
+ regulatory T cells. Arthritis Rheum. 52: 2212-2221.
-
(2005)
Arthritis Rheum.
, vol.52
, pp. 2212-2221
-
-
Morgan, M.E.1
Flierman, R.2
Van Duivenvoorde, L.M.3
Witteveen, H.J.4
Van Ewijk, W.5
Van Laar, J.M.6
De Vries, R.R.7
Toes, R.E.8
-
6
-
-
22144466887
-
+ Tregs
-
DOI 10.1172/JCI23963
-
Valmori, D., A. Merlo, N. E. Souleimanian, C. S. Hesdorffer, and M. Ayyoub. 2005. A peripheral circulating compartment of natural naive CD4 Tregs. J. Clin. Invest. 115: 1953-1962. (Pubitemid 40979735)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.7
, pp. 1953-1962
-
-
Valmori, D.1
Merlo, A.2
Souleimanian, N.E.3
Hesdorffer, C.S.4
Ayyoub, M.5
-
8
-
-
37549032709
-
+ T regulatory cells by activation independent expression of FOXP3
-
+ T regulatory cells by activation independent expression of FOXP3. Mol. Ther. 16: 194-202.
-
(2008)
Mol. Ther.
, vol.16
, pp. 194-202
-
-
Allan, S.E.1
Alstad, A.N.2
Merindol, N.3
Crellin, N.K.4
Amendola, M.5
Bacchetta, R.6
Naldini, L.7
Roncarolo, M.G.8
Soudeyns, H.9
Levings, M.K.10
-
10
-
-
0035806323
-
+ T regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function
-
+ T regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function. J. Exp. Med. 193: 1295-1302.
-
(2001)
J. Exp. Med.
, vol.193
, pp. 1295-1302
-
-
Levings, M.K.1
Sangregorio, R.2
Roncarolo, M.G.3
-
11
-
-
33846340789
-
FOXP3: Not just for regulatory T cells anymore
-
DOI 10.1002/eji.200636929
-
Ziegler, S. F. 2007. FOXP3: not just for regulatory T cells anymore. Eur. J. Immunol. 37: 21-23. (Pubitemid 46128782)
-
(2007)
European Journal of Immunology
, vol.37
, Issue.1
, pp. 21-23
-
-
Ziegler, S.F.1
-
12
-
-
44849100619
-
Is FOXP3 a bona fide marker for human regulatory T cells?
-
Roncarolo, M. G., and S. Gregori. 2008. Is FOXP3 a bona fide marker for human regulatory T cells? Eur. J. Immunol. 38: 925-927.
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 925-927
-
-
Roncarolo, M.G.1
Gregori, S.2
-
13
-
-
33745817085
-
+ T reg cells
-
+ T reg cells. J. Exp. Med. 203: 1701-1711.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 1701-1711
-
-
Liu, W.1
Putnam, A.L.2
Xu-Yu, Z.3
Szot, G.L.4
Lee, M.R.5
Zhu, S.6
Gottlieb, P.A.7
Kapranov, P.8
Gingeras, T.R.9
Fazekas De St Groth, B.10
-
14
-
-
52049118092
-
Clinical grade Treg: GMP isolation, improvement of purity by CD127 depletion, Treg expansion, and Treg cryopreservation
-
Peters, J. H., F. W. Preijers, R. Woestenenk, L. B. Hilbrands, H. J. Koenen, and I. Joosten. 2008. Clinical grade Treg: GMP isolation, improvement of purity by CD127 depletion, Treg expansion, and Treg cryopreservation. PLoS ONE 3: e3161.
-
(2008)
PLoS ONE
, vol.3
-
-
Peters, J.H.1
Preijers, F.W.2
Woestenenk, R.3
Hilbrands, L.B.4
Koenen, H.J.5
Joosten, I.6
-
18
-
-
3543140687
-
Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFα therapy
-
Ehrenstein, M. R., J. G. Evans, A. Singh, S. Moore, G. Warnes, D. A. Isenberg, and C. Mauri. 2004. Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFα therapy. J. Exp. Med. 200: 277-285.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 277-285
-
-
Ehrenstein, M.R.1
Evans, J.G.2
Singh, A.3
Moore, S.4
Warnes, G.5
Isenberg, D.A.6
Mauri, C.7
-
22
-
-
8344275995
-
+ regulatory T cells
-
+ regulatory T cells. Int. Immunol. 16: 1643-1656.
-
(2004)
Int. Immunol.
, vol.16
, pp. 1643-1656
-
-
Yagi, H.1
Nomura, T.2
Nakamura, K.3
Yamazaki, S.4
Kitawaki, T.5
Hori, S.6
Maeda, M.7
Onodera, M.8
Uchiyama, T.9
Fujii, S.10
Sakaguchi, S.11
-
23
-
-
27644449311
-
+ Tregs
-
+ Tregs. J. Clin. Invest. 115: 3276-3284.
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 3276-3284
-
-
Allan, S.E.1
Passerini, L.2
Bacchetta, R.3
Crellin, N.4
Dai, M.5
Orban, P.C.6
Ziegler, S.F.7
Roncarolo, M.G.8
Levings, M.K.9
-
26
-
-
33947121146
-
Transient regulatory T-cells: A state attained by all activated human T-cells
-
DOI 10.1016/j.clim.2006.10.014, PII S1521661606009405
-
Pillai, V., S. B. Ortega, C. K. Wang, and N. J. Karandikar. 2007. Transient regulatory T cells: a state attained by all activated human T cells. Clin. Immunol. 123: 18-29. (Pubitemid 46401504)
-
(2007)
Clinical Immunology
, vol.123
, Issue.1
, pp. 18-29
-
-
Pillai, V.1
Ortega, S.B.2
Wang, C.K.3
Karandikar, N.J.4
-
27
-
-
12444279957
-
Differentiation and expansion of T cells with regulatory function from human peripheral lymphocytes by stimulation in the presence of TGF-β
-
Rao, P. E., A. L. Petrone, and P. D. Ponath. 2005. Differentiation and expansion of T cells with regulatory function from human peripheral lymphocytes by stimulation in the presence of TGF-β. J. Immunol. 174: 1446-1455.
-
(2005)
J. Immunol.
, vol.174
, pp. 1446-1455
-
-
Rao, P.E.1
Petrone, A.L.2
Ponath, P.D.3
-
29
-
-
34047174849
-
Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production
-
Allan, S. E., S. Q. Crome, N. K. Crellin, L. Passerini, T. S. Steiner, R. Bacchetta, M. G. Roncarolo, and M. K. Levings. 2007. Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production. Int. Immunol. 19: 345-354.
-
(2007)
Int. Immunol.
, vol.19
, pp. 345-354
-
-
Allan, S.E.1
Crome, S.Q.2
Crellin, N.K.3
Passerini, L.4
Steiner, T.S.5
Bacchetta, R.6
Roncarolo, M.G.7
Levings, M.K.8
-
30
-
-
35448930435
-
+FOXP3 T cells by T cell receptor stimulation is transforming growth factor β dependent but does not confer a regulatory phenotype
-
+FOXP3 T cells by T cell receptor stimulation is transforming growth factor β dependent but does not confer a regulatory phenotype. Blood 110: 2983-2990.
-
(2007)
Blood
, vol.110
, pp. 2983-2990
-
-
Tran, D.Q.1
Ramsey, H.2
Shevach, E.M.3
-
31
-
-
34447503805
-
H17 and regulatory T cell differentiation mediated by retinoic acid
-
DOI 10.1126/science.1145697
-
Mucida, D., Y. Park, G. Kim, O. Turovskaya, I. Scott, M. Kronenberg, and H. Cheroutre. 2007. Reciprocal Th17 and regulatory T cell differentiation mediated by retinoic acid. Science 317: 256-260. (Pubitemid 47076203)
-
(2007)
Science
, vol.317
, Issue.5835
, pp. 256-260
-
-
Mucida, D.1
Park, Y.2
Kim, G.3
Turovskaya, O.4
Scott, I.5
Kronenberg, M.6
Cheroutre, H.7
-
33
-
-
34547757390
-
Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid
-
Sun, C. M., J. A. Hall, R. B. Blank, N. Bouladoux, M. Oukka, J. R. Mora, and Y. Belkaid. 2007. Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid. J. Exp. Med. 204: 1775-1785.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1775-1785
-
-
Sun, C.M.1
Hall, J.A.2
Blank, R.B.3
Bouladoux, N.4
Oukka, M.5
Mora, J.R.6
Belkaid, Y.7
-
34
-
-
34547769253
-
All-trans-retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of costimulation
-
Benson, M. J., K. Pino-Lagos, M. Rosemblatt, and R. J. Noelle. 2007. All-trans-retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of costimulation. J. Exp. Med. 204: 1765-1774.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1765-1774
-
-
Benson, M.J.1
Pino-Lagos, K.2
Rosemblatt, M.3
Noelle, R.J.4
-
35
-
-
34548762585
-
Activation of retinoic acid receptor-α favours regulatory T cell induction at the expense of IL-17-secreting T helper cell differentiation
-
DOI 10.1002/eji.200737621
-
Schambach, F., M. Schupp, M. A. Lazar, and S. L. Reiner. 2007. Activation of retinoic acid receptor α favours regulatory T cell induction at the expense of IL-17-secreting T helper cell differentiation. Eur. J. Immunol. 37: 2396-2399. (Pubitemid 47423609)
-
(2007)
European Journal of Immunology
, vol.37
, Issue.9
, pp. 2396-2399
-
-
Schambach, F.1
Schupp, M.2
Lazar, M.A.3
Reiner, S.L.4
-
36
-
-
38949164425
-
Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathway
-
Elias, K. M., A. Laurence, T. S. Davidson, G. Stephens, Y. Kanno, E. M. Shevach, and J. J. O'Shea. 2008. Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathway. Blood 111: 1013-1020.
-
(2008)
Blood
, vol.111
, pp. 1013-1020
-
-
Elias, K.M.1
Laurence, A.2
Davidson, T.S.3
Stephens, G.4
Kanno, Y.5
Shevach, E.M.6
O'Shea, J.J.7
-
37
-
-
53149137849
-
+ regulatory T cells and inhibits development of Th17 cells by enhancing TGF-β-driven Smad3 signaling and inhibiting IL-6 and IL-23 receptor expression
-
+ regulatory T cells and inhibits development of Th17 cells by enhancing TGF-β-driven Smad3 signaling and inhibiting IL-6 and IL-23 receptor expression. J. Immunol. 181: 2277-2284.
-
(2008)
J. Immunol.
, vol.181
, pp. 2277-2284
-
-
Xiao, S.1
Jin, H.2
Korn, T.3
Liu, S.M.4
Oukka, M.5
Lim, B.6
Kuchroo, V.K.7
-
38
-
-
55549084247
-
high cells
-
high cells. Immunity 29: 758-770.
-
(2008)
Immunity
, vol.29
, pp. 758-770
-
-
Hill, J.A.1
Hall, J.A.2
Sun, C.M.3
Cai, Q.4
Ghyselinck, N.5
Chambon, P.6
Belkaid, Y.7
Mathis, D.8
Benoist, C.9
-
39
-
-
64049110576
-
+ Treg cell conversion of naive T cells
-
+ Treg cell conversion of naive T cells. Immunity 30: 471-472.
-
(2009)
Immunity
, vol.30
, pp. 471-472
-
-
Mucida, D.1
Pino-Lagos, K.2
Kim, G.3
Nowak, E.4
Benson, M.J.5
Kronenberg, M.6
Noelle, R.J.7
Cheroutre, H.8
-
42
-
-
38049110724
-
Attack on the clones? Human FOXP3 detection by PCH101, 236A/E7, 206D, and 259D reveals 259D as the outlier with lower sensitivity
-
Pillai, V., and N. J. Karandikar. 2008. Attack on the clones? Human FOXP3 detection by PCH101, 236A/E7, 206D, and 259D reveals 259D as the outlier with lower sensitivity. Blood 111: 463-464.
-
(2008)
Blood
, vol.111
, pp. 463-464
-
-
Pillai, V.1
Karandikar, N.J.2
-
44
-
-
34848876937
-
- T cells
-
- T cells. J. Immunol. 179: 2041-2045.
-
(2007)
J. Immunol.
, vol.179
, pp. 2041-2045
-
-
Dominitzki, S.1
Fantini, M.C.2
Neufert, C.3
Nikolaev, A.4
Galle, P.R.5
Scheller, J.6
Monteleone, G.7
Rose-John, S.8
Neurath, M.F.9
Becker, C.10
-
45
-
-
47249085266
-
STAT6 Inhibits TGF-β1-mediated Foxp3 induction through direct binding to the Foxp3 promoter, which is reverted by retinoic acid receptor
-
Takaki, H., K. Ichiyama, K. Koga, T. Chinen, G. Takaesu, Y. Sugiyama, S. Kato, A. Yoshimura, and T. Kobayashi. 2008. STAT6 Inhibits TGF-β1-mediated Foxp3 induction through direct binding to the Foxp3 promoter, which is reverted by retinoic acid receptor. J. Biol. Chem. 283: 14955-14962.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 14955-14962
-
-
Takaki, H.1
Ichiyama, K.2
Koga, K.3
Chinen, T.4
Takaesu, G.5
Sugiyama, Y.6
Kato, S.7
Yoshimura, A.8
Kobayashi, T.9
-
46
-
-
59749103715
-
Inducible reprogramming of human T cells into Treg cells by a conditionally active form of FOXP3
-
Allan, S. E., G. X. Song-Zhao, T. Abraham, A. N. McMurchy, and M. K. Levings. 2008. Inducible reprogramming of human T cells into Treg cells by a conditionally active form of FOXP3. Eur. J. Immunol. 38: 3282-3289.
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 3282-3289
-
-
Allan, S.E.1
Song-Zhao, G.X.2
Abraham, T.3
McMurchy, A.N.4
Levings, M.K.5
-
47
-
-
33746189406
-
FOXP3 and NFAT: Partners in tolerance
-
Rudensky, A. Y., M. Gavin, and Y. Zheng. 2006. FOXP3 and NFAT: partners in tolerance. Cell 126: 253-256.
-
(2006)
Cell
, vol.126
, pp. 253-256
-
-
Rudensky, A.Y.1
Gavin, M.2
Zheng, Y.3
-
48
-
-
53749094183
-
+ regulatory T cell function
-
+ regulatory T cell function. Science 322: 271-275.
-
(2008)
Science
, vol.322
, pp. 271-275
-
-
Wing, K.1
Onishi, Y.2
Prieto-Martin, P.3
Yamaguchi, T.4
Miyara, M.5
Fehervari, Z.6
Nomura, T.7
Sakaguchi, S.8
-
49
-
-
58249112156
-
CTLA-4 (CD152) controls homeostasis and suppressive capacity of regulatory T cells in mice
-
Kolar, P., K. Knieke, J. K. Hegel, D. Quandt, G. R. Burmester, H. Hoff, and M. C. Brunner-Weinzierl. 2009. CTLA-4 (CD152) controls homeostasis and suppressive capacity of regulatory T cells in mice. Arthritis Rheum. 60: 123-132.
-
(2009)
Arthritis Rheum.
, vol.60
, pp. 123-132
-
-
Kolar, P.1
Knieke, K.2
Hegel, J.K.3
Quandt, D.4
Burmester, G.R.5
Hoff, H.6
Brunner-Weinzierl, M.C.7
|