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Volumn 23, Issue 9, 2009, Pages 1577-1586

Involvement of mast cells by the malignant process in patients with Philadelphia chromosome negative myeloproliferative neoplasms

Author keywords

JAK2V617F; Mast cell; MplW515L; Myeloproliferative neoplasms

Indexed keywords

CD34 ANTIGEN; ERLOTINIB; JAK2 PROTEIN, HUMAN; JANUS KINASE 2; MPL PROTEIN, HUMAN; QUINAZOLINE DERIVATIVE; THROMBOPOIETIN RECEPTOR;

EID: 70349306855     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2009.85     Document Type: Article
Times cited : (14)

References (55)
  • 1
    • 13544275273 scopus 로고    scopus 로고
    • The polycythemias
    • Hoffman R, Benz Jr E, Shattil S, Furie B, Silberstein L, McGlave P, Heslop H (eds) 5th edn. Churchill Livingstone: Philadelphia
    • Hoffman R, Xu M, Finazzi G, Barbui T. The polycythemias. In: Hoffman R, Benz Jr E, Shattil S, Furie B, Silberstein L, McGlave P, Heslop H (eds). Hematology: Basic Principles and Practice, 5th edn. Churchill Livingstone: Philadelphia, 2008, 1073-1108.
    • (2008) Hematology: Basic Principles and Practice , pp. 1073-1108
    • Hoffman, R.1    Xu, M.2    Finazzi, G.3    Barbui, T.4
  • 2
    • 0141498506 scopus 로고    scopus 로고
    • Clinical and scientific advances in the Philadelphiachromosome negative chronic myeloproliferative disorders
    • Mesa RA. Clinical and scientific advances in the Philadelphiachromosome negative chronic myeloproliferative disorders. Int J Hematol 2002; 76: 193-203.
    • (2002) Int J Hematol , vol.76 , pp. 193-203
    • Mesa, R.A.1
  • 3
    • 34547771593 scopus 로고    scopus 로고
    • Cytogenetic and molecular aspects of Philadelphia negative chronic myeloproliferative disorders: Clinical implications
    • Review
    • Panani AD. Cytogenetic and molecular aspects of Philadelphia negative chronic myeloproliferative disorders: clinical implications. Cancer Lett 2007; 255: 12-25. Review.
    • (2007) Cancer Lett , vol.255 , pp. 12-25
    • Panani, A.D.1
  • 4
    • 0036439588 scopus 로고    scopus 로고
    • Exploring polycythaemia vera with fluorescence in situ hybridization: Additional cryptic 9p is the most frequent abnormality detected
    • Najfeld V, Montella L, Scalise A, Fruchtman S. Exploring polycythaemia vera with fluorescence in situ hybridization: additional cryptic 9p is the most frequent abnormality detected. Br J Haematol 2002; 119: 558-566.
    • (2002) Br J Haematol , vol.119 , pp. 558-566
    • Najfeld, V.1    Montella, L.2    Scalise, A.3    Fruchtman, S.4
  • 5
    • 20144363192 scopus 로고    scopus 로고
    • Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
    • Baxter EJ, Scott LM, Campbell PJ, East C, Fourouclas N, Swanton S et al. Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders. Lancet 2005; 365: 1054-1061.
    • (2005) Lancet , vol.365 , pp. 1054-1061
    • Baxter, E.J.1    Scott, L.M.2    Campbell, P.J.3    East, C.4    Fourouclas, N.5    Swanton, S.6
  • 6
    • 20244369569 scopus 로고    scopus 로고
    • Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
    • Levine RL, Wadleigh M, Cools J, Ebert BL, Wernig G, Huntly BJ et al. Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell 2005; 7: 387-397.
    • (2005) Cancer Cell , vol.7 , pp. 387-397
    • Levine, R.L.1    Wadleigh, M.2    Cools, J.3    Ebert, B.L.4    Wernig, G.5    Huntly, B.J.6
  • 7
    • 17844383458 scopus 로고    scopus 로고
    • A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
    • James C, Ugo V, Le Couédic JP, Staerk J, Delhommeau F, Lacout C et al. A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature 2005; 434: 1144-1148.
    • (2005) Nature , vol.434 , pp. 1144-1148
    • James, C.1    Ugo, V.2    Le Couédic, J.P.3    Staerk, J.4    Delhommeau, F.5    Lacout, C.6
  • 9
    • 20744460045 scopus 로고    scopus 로고
    • Identification of an acquired JAK2 mutation in polycythemia vera
    • Zhao R, Xing S, Li Z, Fu X, Li Q, Krantz SB et al. Identification of an acquired JAK2 mutation in polycythemia vera. J Biol Chem 2005; 280: 22788-22792.
    • (2005) J Biol Chem , vol.280 , pp. 22788-22792
    • Zhao, R.1    Xing, S.2    Li, Z.3    Fu, X.4    Li, Q.5    Krantz, S.B.6
  • 10
    • 33746437130 scopus 로고    scopus 로고
    • MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia
    • Pikman Y, Lee BH, Mercher T, McDowell E, Ebert BL, Gozo M et al. MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia. PLoS Med 2006; 3: e270.
    • (2006) PLoS Med , vol.3
    • Pikman, Y.1    Lee, B.H.2    Mercher, T.3    McDowell, E.4    Ebert, B.L.5    Gozo, M.6
  • 11
    • 33750534561 scopus 로고    scopus 로고
    • MPL515 mutations in myeloproliferative and other myeloid disorders: A study of 1182 patients
    • Pardanani AD, Levine RL, Lasho T, Pikman Y, Mesa RA, Wadleigh M et al. MPL515 mutations in myeloproliferative and other myeloid disorders: a study of 1182 patients. Blood 2006; 108: 3472-3476.
    • (2006) Blood , vol.108 , pp. 3472-3476
    • Pardanani, A.D.1    Levine, R.L.2    Lasho, T.3    Pikman, Y.4    Mesa, R.A.5    Wadleigh, M.6
  • 12
    • 33744490974 scopus 로고    scopus 로고
    • Expression of Jak2V617F causes a polycythemia vera-like disease with associated myelofibrosis in a murine bone marrow transplant model
    • Wernig G, Mercher T, Okabe R, Levine RL, Lee BH, Gilliland DG. Expression of Jak2V617F causes a polycythemia vera-like disease with associated myelofibrosis in a murine bone marrow transplant model. Blood 2006; 107: 4274-4281.
    • (2006) Blood , vol.107 , pp. 4274-4281
    • Wernig, G.1    Mercher, T.2    Okabe, R.3    Levine, R.L.4    Lee, B.H.5    Gilliland, D.G.6
  • 13
    • 33745721197 scopus 로고    scopus 로고
    • JAK2V617F expression in murine hematopoietic cells leads to MPD mimicking human PV with secondary myelofibrosis
    • Lacout C, Pisani DF, Tulliez M, Gachelin FM, Vainchenker W, Villeval JL. JAK2V617F expression in murine hematopoietic cells leads to MPD mimicking human PV with secondary myelofibrosis. Blood 2006; 108: 1652-1660.
    • (2006) Blood , vol.108 , pp. 1652-1660
    • Lacout, C.1    Pisani, D.F.2    Tulliez, M.3    Gachelin, F.M.4    Vainchenker, W.5    Villeval, J.L.6
  • 14
    • 34447642422 scopus 로고    scopus 로고
    • Molecular pathogenesis and therapy of polycythemia induced in mice by JAK2V617F
    • Zaleskas VM, Krause DS, Lazarides K, Patel N, Hu Y, Li S et al. Molecular pathogenesis and therapy of polycythemia induced in mice by JAK2V617F. PLoS ONE 2006; 1: e18.
    • (2006) PLoS ONE , vol.1
    • Zaleskas, V.M.1    Krause, D.S.2    Lazarides, K.3    Patel, N.4    Hu, Y.5    Li, S.6
  • 15
    • 33845798378 scopus 로고    scopus 로고
    • Characterization of murine JAK2V617F-positive myeloproliferative disease
    • Bumm TG, Elsea C, Corbin AS, Loriaux M, Sherbenou D, Wood L et al. Characterization of murine JAK2V617F-positive myeloproliferative disease. Cancer Res 2006; 66: 11156-11165.
    • (2006) Cancer Res , vol.66 , pp. 11156-11165
    • Bumm, T.G.1    Elsea, C.2    Corbin, A.S.3    Loriaux, M.4    Sherbenou, D.5    Wood, L.6
  • 16
    • 46749137278 scopus 로고    scopus 로고
    • Transgenic expression of JAK2V617F causes myeloproliferative disorders in mice
    • Xing S, Wanting TH, Zhao W, Ma J, Wang S, Xu X et al. Transgenic expression of JAK2V617F causes myeloproliferative disorders in mice. Blood 2008; 111: 5109-5117.
    • (2008) Blood , vol.111 , pp. 5109-5117
    • Xing, S.1    Wanting, T.H.2    Zhao, W.3    Ma, J.4    Wang, S.5    Xu, X.6
  • 17
    • 38349035684 scopus 로고    scopus 로고
    • Development of et primary myelofibrosis and PV in mice expressing JAK2V617F
    • Shide K, Shimoda HK, Kumano T, Karube K, Kameda T, Takenaka K et al. Development of ET, primary myelofibrosis and PV in mice expressing JAK2V617F. Leukemia 2008; 22: 87-95.
    • (2008) Leukemia , vol.22 , pp. 87-95
    • Shide, K.1    Shimoda, H.K.2    Kumano, T.3    Karube, K.4    Kameda, T.5    Takenaka, K.6
  • 18
    • 43249084493 scopus 로고    scopus 로고
    • Ratio of mutant JAK2V617F to wild-type Jak2 determines the MPD phenotypes in transgenic mice
    • Tiedt R, Hao-Shen H, Sobas MA, Looser R, Dirnhofer S, Schwaller J et al. Ratio of mutant JAK2V617F to wild-type Jak2 determines the MPD phenotypes in transgenic mice. Blood 2008; 111: 3931-3940.
    • (2008) Blood , vol.111 , pp. 3931-3940
    • Tiedt, R.1    Hao-Shen, H.2    Sobas, M.A.3    Looser, R.4    Dirnhofer, S.5    Schwaller, J.6
  • 20
    • 0019818299 scopus 로고
    • Evidence that essential thrombocythemia is a clonal disorder with origin in a multipotent stem cell
    • Fialkow PJ, Faguet GB, Jacobson RJ, Vaidya K, Murphy S. Evidence that essential thrombocythemia is a clonal disorder with origin in a multipotent stem cell. Blood 1981; 58: 916-919.
    • (1981) Blood , vol.58 , pp. 916-919
    • Fialkow, P.J.1    Faguet, G.B.2    Jacobson, R.J.3    Vaidya, K.4    Murphy, S.5
  • 21
    • 0021956939 scopus 로고
    • Evidence for the involvement of B lymphoid cells in polycythemia vera and essential thrombocythemia
    • Raskind WH, Jacobson R, Murphy S, Adamson JW, Fialkow PJ. Evidence for the involvement of B lymphoid cells in polycythemia vera and essential thrombocythemia. J Clin Invest 1985; 75: 1388-1390.
    • (1985) J Clin Invest , vol.75 , pp. 1388-1390
    • Raskind, W.H.1    Jacobson, R.2    Murphy, S.3    Adamson, J.W.4    Fialkow, P.J.5
  • 22
    • 0028362575 scopus 로고
    • Clonality in chronic myeloproliferative disorders defined by X-chromosome linked probes: Demonstration of heterogeneity in lineage involvement
    • Tsukamoto N, Morita K, Maehara T, Okamoto K, Sakai H, Karasawa M et al. Clonality in chronic myeloproliferative disorders defined by X-chromosome linked probes: demonstration of heterogeneity in lineage involvement. Br J Haematol 1994; 86: 253-258.
    • (1994) Br J Haematol , vol.86 , pp. 253-258
    • Tsukamoto, N.1    Morita, K.2    Maehara, T.3    Okamoto, K.4    Sakai, H.5    Karasawa, M.6
  • 23
    • 0020602184 scopus 로고
    • Polycythaemia rubra vera associated with unbalanced expression of the X chromosome and monoclonality of T lymphocytes
    • Williams CK, Ogunmola GB, Abugo O, Ukaejiofo EO, Esan GJ. Polycythaemia rubra vera associated with unbalanced expression of the X chromosome and monoclonality of T lymphocytes. Acta Haematol 1983; 70: 229-235.
    • (1983) Acta Haematol , vol.70 , pp. 229-235
    • Williams, C.K.1    Ogunmola, G.B.2    Abugo, O.3    Ukaejiofo, E.O.4    Esan, G.J.5
  • 24
    • 0023753816 scopus 로고
    • Evidence for pluripotent stem cell origin of idiopathic myelofibrosis: Clonal analysis of a case characterized by a N-ras gene mutation
    • Buschle M, Janssen JW, Drexler H, Lyons J, Anger B, Bartram CR. Evidence for pluripotent stem cell origin of idiopathic myelofibrosis: clonal analysis of a case characterized by a N-ras gene mutation. Leukemia 1988; 2: 658-660.
    • (1988) Leukemia , vol.2 , pp. 658-660
    • Buschle, M.1    Janssen, J.W.2    Drexler, H.3    Lyons, J.4    Anger, B.5    Bartram, C.R.6
  • 25
    • 0037372287 scopus 로고    scopus 로고
    • Both B and T lymphocytes may be clonally involved in myelofibrosis with myeloid metaplasia
    • Reeder TL, Bailey RJ, Dewald GW, Tefferi A. Both B and T lymphocytes may be clonally involved in myelofibrosis with myeloid metaplasia. Blood 2003; 101: 1981-1983.
    • (2003) Blood , vol.101 , pp. 1981-1983
    • Reeder, T.L.1    Bailey, R.J.2    Dewald, G.W.3    Tefferi, A.4
  • 26
    • 0036191941 scopus 로고    scopus 로고
    • Acquired uniparental disomy of chromosome 9p is a frequent stem cell defect in polycythemia vera
    • Kralovics R, Guan Y, Prchal JT. Acquired uniparental disomy of chromosome 9p is a frequent stem cell defect in polycythemia vera. Exp Hematol 2002; 30: 229-236.
    • (2002) Exp Hematol , vol.30 , pp. 229-236
    • Kralovics, R.1    Guan, Y.2    Prchal, J.T.3
  • 27
    • 21344465615 scopus 로고    scopus 로고
    • Clonality and molecular pathogenesis of mastocytosis
    • Akin C. Clonality and molecular pathogenesis of mastocytosis. Acta Haematol 2005; 114: 61-69.
    • (2005) Acta Haematol , vol.114 , pp. 61-69
    • Akin, C.1
  • 28
    • 33750611344 scopus 로고    scopus 로고
    • Involvement of various hematopoietic-cell lineages by the JAK2V617F mutation in polycythemia vera
    • Ishii T, Bruno E, Hoffman R, Xu M. Involvement of various hematopoietic-cell lineages by the JAK2V617F mutation in polycythemia vera. Blood 2006; 108: 3128-3134.
    • (2006) Blood , vol.108 , pp. 3128-3134
    • Ishii, T.1    Bruno, E.2    Hoffman, R.3    Xu, M.4
  • 29
    • 33646546386 scopus 로고    scopus 로고
    • The JAK2V617F mutation occurs in hematopoietic stem cells in polycythemia vera and predisposes toward erythroid differentiation
    • Jamieson CH, Gotlib J, Durocher JA, Chao MP, Mariappan MR, Lay M et al. The JAK2V617F mutation occurs in hematopoietic stem cells in polycythemia vera and predisposes toward erythroid differentiation. Proc Natl Acad Sci USA 2006; 103: 6224-6229.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 6224-6229
    • Jamieson, C.H.1    Gotlib, J.2    Durocher, J.A.3    Chao, M.P.4    Mariappan, M.R.5    Lay, M.6
  • 30
    • 33846007215 scopus 로고    scopus 로고
    • Evidence that the JAK2G1849T (V617F) mutation occurs in a lymphomyeloid progenitor in polycythemia vera and diopathic myelofibrosis
    • Delhommeau F, Dupont S, Tonetti C, Massé A, Godin I, Le Couedic JP et al. Evidence that the JAK2G1849T (V617F) mutation occurs in a lymphomyeloid progenitor in polycythemia vera and diopathic myelofibrosis. Blood 2007; 109: 71-77.
    • (2007) Blood , vol.109 , pp. 71-77
    • Delhommeau, F.1    Dupont, S.2    Tonetti, C.3    Massé, A.4    Godin, I.5    Le Couedic, J.P.6
  • 31
    • 33846976182 scopus 로고    scopus 로고
    • The JAK2V617F mutation involves B-and T-lymphocyte lineages in a subgroup of patients with Philadelphia-chromosome negative chronic myeloproliferative disorders
    • Larsen TS, Christensen JH, Hasselbalch HC, Pallisgaard N. The JAK2V617F mutation involves B-and T-lymphocyte lineages in a subgroup of patients with Philadelphia-chromosome negative chronic myeloproliferative disorders. Br J Haematol 2007; 136: 745-751.
    • (2007) Br J Haematol , vol.136 , pp. 745-751
    • Larsen, T.S.1    Christensen, J.H.2    Hasselbalch, H.C.3    Pallisgaard, N.4
  • 32
    • 34247473543 scopus 로고    scopus 로고
    • Haematopoietic cell lineage distribution of MPLW515L/K mutations in patients with idiopathic myelofibrosis
    • Hu WY, Zhao Y, Ishii T, Sozer S, Shi J, Zhang W et al. Haematopoietic cell lineage distribution of MPLW515L/K mutations in patients with idiopathic myelofibrosis. Br J Haematol 2007; 137: 378-379.
    • (2007) Br J Haematol , vol.137 , pp. 378-379
    • Hu, W.Y.1    Zhao, Y.2    Ishii, T.3    Sozer, S.4    Shi, J.5    Zhang, W.6
  • 33
    • 36348999273 scopus 로고    scopus 로고
    • Evidence for MPLW515L/K mutations in hematopoietic stem cells in primitive myelofibrosis
    • Chaligné R, James C, Tonetti C, Besancenot R, Le Couédic JP, Fava F et al. Evidence for MPLW515L/K mutations in hematopoietic stem cells in primitive myelofibrosis. Blood 2007; 110: 3735-3743.
    • (2007) Blood , vol.110 , pp. 3735-3743
    • Chaligné, R.1    James, C.2    Tonetti, C.3    Besancenot, R.4    Le Couédic, J.P.5    Fava, F.6
  • 34
    • 38349101871 scopus 로고    scopus 로고
    • Classification and diagnosis of myeloproliferative neoplasms: The 2008 World Health Organization criteria and point-of-care diagnostic algorithms
    • Tefferi A, Vardiman JW. Classification and diagnosis of myeloproliferative neoplasms: the 2008 World Health Organization criteria and point-of-care diagnostic algorithms. Leukemia 2008; 22: 14-22.
    • (2008) Leukemia , vol.22 , pp. 14-22
    • Tefferi, A.1    Vardiman, J.W.2
  • 35
    • 13544254271 scopus 로고    scopus 로고
    • The constitutive mobilization of bone marrow-repopulating cells into the peripheral blood in idiopathic myelofibrosis
    • Xu M, Bruno E, Chao J, Ni H, Lindgren V, Nunez R et al. The constitutive mobilization of bone marrow-repopulating cells into the peripheral blood in idiopathic myelofibrosis. Blood 2005; 105: 1699-1705.
    • (2005) Blood , vol.105 , pp. 1699-1705
    • Xu, M.1    Bruno, E.2    Chao, J.3    Ni, H.4    Lindgren, V.5    Nunez, R.6
  • 36
    • 0031964971 scopus 로고    scopus 로고
    • Interleukin-4 promotes the development of tryptase and chymase double-positive human mast cells accompanied by cell maturation
    • Toru H, Eguchi M, Matsumoto R, Yanagida M, Yata J, Nakahata T. Interleukin-4 promotes the development of tryptase and chymase double-positive human mast cells accompanied by cell maturation. Blood 1998; 91: 187-195.
    • (1998) Blood , vol.91 , pp. 187-195
    • Toru, H.1    Eguchi, M.2    Matsumoto, R.3    Yanagida, M.4    Yata, J.5    Nakahata, T.6
  • 37
    • 34248648755 scopus 로고    scopus 로고
    • Culture of human mast cells from peripheral blood progenitors
    • Saito H, Kato A, Matsumoto K, Okayama Y. Culture of human mast cells from peripheral blood progenitors. Nat Protoc 2006; 1: 2178-2183.
    • (2006) Nat Protoc , vol.1 , pp. 2178-2183
    • Saito, H.1    Kato, A.2    Matsumoto, K.3    Okayama, Y.4
  • 38
    • 33947541141 scopus 로고    scopus 로고
    • Erlotinib effectively inhibits JAK2V617F activity and polycythemia vera cell growth
    • Li Z, Xu M, Xing S, Ho WT, Ishii T, Li Q et al. Erlotinib effectively inhibits JAK2V617F activity and polycythemia vera cell growth. J Biol Chem 2007; 282: 3428-3432.
    • (2007) J Biol Chem , vol.282 , pp. 3428-3432
    • Li, Z.1    Xu, M.2    Xing, S.3    Ho, W.T.4    Ishii, T.5    Li, Q.6
  • 39
    • 36348996511 scopus 로고    scopus 로고
    • T cells from patients with polycythemia vera elaborate growth factors which contribute to endogenous erythroid and megakaryocyte colony formation
    • Ishii T, Zhao Y, Shi J, Sozer S, Hoffman R, Xu M. T cells from patients with polycythemia vera elaborate growth factors which contribute to endogenous erythroid and megakaryocyte colony formation. Leukemia 2007; 21: 2433-2441.
    • (2007) Leukemia , vol.21 , pp. 2433-2441
    • Ishii, T.1    Zhao, Y.2    Shi, J.3    Sozer, S.4    Hoffman, R.5    Xu, M.6
  • 40
    • 33846917131 scopus 로고    scopus 로고
    • The hypomorphic Gata1low mutation alters the proliferation/ differentiation potential of the common megakaryocytic-erythroid progenitor
    • Ghinassi B, Sanchez M, Martelli F, Amabile G, Vannucchi AM, Migliaccio G et al. The hypomorphic Gata1low mutation alters the proliferation/ differentiation potential of the common megakaryocytic-erythroid progenitor. Blood 2007; 109: 1460-1471.
    • (2007) Blood , vol.109 , pp. 1460-1471
    • Ghinassi, B.1    Sanchez, M.2    Martelli, F.3    Amabile, G.4    Vannucchi, A.M.5    Migliaccio, G.6
  • 41
    • 0027715015 scopus 로고
    • The human IgE network
    • Review
    • Sutton BJ, Gould HJ. The human IgE network. Nature 1993; 366: 421-428. Review.
    • (1993) Nature , vol.366 , pp. 421-428
    • Sutton, B.J.1    Gould, H.J.2
  • 42
    • 0026709365 scopus 로고
    • Conservation of signal transduction mechanisms via the human Fc epsilon RI alpha after transfection into a rat mast cell line, RBL 2H3
    • Gilfillan AM, Kado-Fong H, Wiggan GA, Hakimi J, Kent U, Kochan JP. Conservation of signal transduction mechanisms via the human Fc epsilon RI alpha after transfection into a rat mast cell line, RBL 2H3. J Immunol 1992; 149: 2445-2451.
    • (1992) J Immunol , vol.149 , pp. 2445-2451
    • Gilfillan, A.M.1    Kado-Fong, H.2    Wiggan, G.A.3    Hakimi, J.4    Kent, U.5    Kochan, J.P.6
  • 43
    • 22244480680 scopus 로고    scopus 로고
    • Fc{epsilon}RI-mediated mast cell degranulation requires calciumindependent microtubule-dependent translocation of granules to the plasma membrane
    • Nishida K, Yamasaki S, Ito Y, Kabu K, Hattori K, Tezuka T et al. Fc{epsilon}RI-mediated mast cell degranulation requires calciumindependent microtubule-dependent translocation of granules to the plasma membrane. J Cell Biol 2005; 170: 115-126.
    • (2005) J Cell Biol , vol.170 , pp. 115-126
    • Nishida, K.1    Yamasaki, S.2    Ito, Y.3    Kabu, K.4    Hattori, K.5    Tezuka, T.6
  • 44
    • 0029871686 scopus 로고    scopus 로고
    • Surface expression of CD63 antigen (AD1 antigen) in P815 mastocytoma cells by transfected IgE receptors
    • Furuno T, Teshima R, Kitani S, Sawada J, Nakanishi M. Surface expression of CD63 antigen (AD1 antigen) in P815 mastocytoma cells by transfected IgE receptors. Biochem Biophys Res Commun 1996; 219: 740-744.
    • (1996) Biochem Biophys Res Commun , vol.219 , pp. 740-744
    • Furuno, T.1    Teshima, R.2    Kitani, S.3    Sawada, J.4    Nakanishi, M.5
  • 45
    • 0032820883 scopus 로고    scopus 로고
    • The CD69 early activation molecule is overexpressed in human bone marrow mast cells from adults with indolent systemic mast cell disease
    • D́az-Agust́n B, Escribano L, Bravo P, Herrero S, Nuñez R, Navalón R et al. The CD69 early activation molecule is overexpressed in human bone marrow mast cells from adults with indolent systemic mast cell disease. Br J Haematol 1999; 106: 400-405.
    • (1999) Br J Haematol , vol.106 , pp. 400-405
    • D́az-Agust́n, B.1    Escribano, L.2    Bravo, P.3    Herrero, S.4    Nuñez, R.5    Navalón, R.6
  • 46
    • 0542420329 scopus 로고    scopus 로고
    • Human bone marrow mast cells from indolent systemic mast cell disease constitutively express increased amounts of the CD63 protein on their surface
    • Escribano L, Orfao A, D́az Agust́n B, Cerveró C, Herrero S, Villarrubia J et al. Human bone marrow mast cells from indolent systemic mast cell disease constitutively express increased amounts of the CD63 protein on their surface. Cytometry 1998; 34: 223-228.
    • (1998) Cytometry , vol.34 , pp. 223-228
    • Escribano, L.1    Orfao, A.2    D́az Agust́n, B.3    Cerveró, C.4    Herrero, S.5    Villarrubia, J.6
  • 47
    • 33749358349 scopus 로고    scopus 로고
    • Progenitors homozygous for the V617F mutation occur in most patients with polycythemia vera, but not essential thrombocythemia
    • Scott LM, Scott MA, Campbell PJ, Green AR. Progenitors homozygous for the V617F mutation occur in most patients with polycythemia vera, but not essential thrombocythemia. Blood 2006; 108: 2435-2437.
    • (2006) Blood , vol.108 , pp. 2435-2437
    • Scott, L.M.1    Scott, M.A.2    Campbell, P.J.3    Green, A.R.4
  • 48
    • 0019793469 scopus 로고
    • Spleen colony-forming cell as common precursor for tissue mast cells and granulocytes
    • Kitamura Y, Yokoyama M, Matsuda H, Ohno T, Mori KJ. Spleen colony-forming cell as common precursor for tissue mast cells and granulocytes. Nature 1981; 291: 159-160.
    • (1981) Nature , vol.291 , pp. 159-160
    • Kitamura, Y.1    Yokoyama, M.2    Matsuda, H.3    Ohno, T.4    Mori, K.J.5
  • 49
    • 0018096538 scopus 로고
    • Decrease of mast cells in W/Wv mice and their increase by bone marrow transplantation
    • Kitamura Y, Go S, Hatanaka K. Decrease of mast cells in W/Wv mice and their increase by bone marrow transplantation. Blood 1978; 52: 447-452.
    • (1978) Blood , vol.52 , pp. 447-452
    • Kitamura, Y.1    Go, S.2    Hatanaka, K.3
  • 50
    • 9144230590 scopus 로고    scopus 로고
    • Development of both human connective tissue-type and mucosal-type mast cells in mice from hematopoietic stem cells with identical distribution pattern to human body
    • Kambe N, Hiramatsu H, Shimonaka M, Fujino H, Nishikomori R, Heike T et al. Development of both human connective tissue-type and mucosal-type mast cells in mice from hematopoietic stem cells with identical distribution pattern to human body. Blood 2004; 103: 860-867.
    • (2004) Blood , vol.103 , pp. 860-867
    • Kambe, N.1    Hiramatsu, H.2    Shimonaka, M.3    Fujino, H.4    Nishikomori, R.5    Heike, T.6
  • 51
    • 41949118675 scopus 로고    scopus 로고
    • Dimerization by a cytokine receptor is necessary for constitutive activation of JAK2V617F
    • Lu X, Huang LJ, Lodish HF. Dimerization by a cytokine receptor is necessary for constitutive activation of JAK2V617F. J Biol Chem 2008; 283: 5258-5266.
    • (2008) J Biol Chem , vol.283 , pp. 5258-5266
    • Lu, X.1    Huang, L.J.2    Lodish, H.F.3
  • 52
    • 47049098437 scopus 로고    scopus 로고
    • Lestaurtinib (CEP701) is a JAK2 inhibitor that suppresses JAK2/STAT5 signaling and the proliferation of primary erythroid cells from patients with myeloproliferative disorders
    • Hexner EO, Serdikoff C, Jan M, Swider CR, Robinson C, Yang S et al. Lestaurtinib (CEP701) is a JAK2 inhibitor that suppresses JAK2/STAT5 signaling and the proliferation of primary erythroid cells from patients with myeloproliferative disorders. Blood 2007; 111: 5663-5671.
    • (2007) Blood , vol.111 , pp. 5663-5671
    • Hexner, E.O.1    Serdikoff, C.2    Jan, M.3    Swider, C.R.4    Robinson, C.5    Yang, S.6
  • 53
    • 38949086558 scopus 로고    scopus 로고
    • WP1066, a novel JAK2 inhibitor, suppresses proliferation and induces apoptosis in erythroid human cells carrying the JAK2V617F mutation
    • Verstovsek S, Manshouri T, Quintás-Cardama A, Harris D, Cortes J, Giles FJ et al. WP1066, a novel JAK2 inhibitor, suppresses proliferation and induces apoptosis in erythroid human cells carrying the JAK2V617F mutation. Clin Cancer Res 2008; 14: 788-796.
    • (2008) Clin Cancer Res , vol.14 , pp. 788-796
    • Verstovsek, S.1    Manshouri, T.2    Quintás-Cardama, A.3    Harris, D.4    Cortes, J.5    Giles, F.J.6
  • 54
    • 41249099841 scopus 로고    scopus 로고
    • Efficacy of TG101348, a selective JAK2 inhibitor, in treatment of a murine model of JAK2V617F-induced polycythemia vera
    • Wernig G, Kharas MG, Okabe R, Moore SA, Leeman DS, Cullen DE et al. Efficacy of TG101348, a selective JAK2 inhibitor, in treatment of a murine model of JAK2V617F-induced polycythemia vera. Cancer Cell 2008; 13: 311-320.
    • (2008) Cancer Cell , vol.13 , pp. 311-320
    • Wernig, G.1    Kharas, M.G.2    Okabe, R.3    Moore, S.A.4    Leeman, D.S.5    Cullen, D.E.6
  • 55
    • 47249129126 scopus 로고    scopus 로고
    • LS104, a non-ATP-competitive smallmolecule inhibitor of JAK2, is potently inducing apoptosis in JAK2V617F-positive cells
    • Lipka DB, Hoffmann LS, Heidel F, Markova B, Blum MC, Breitenbuecher F et al. LS104, a non-ATP-competitive smallmolecule inhibitor of JAK2, is potently inducing apoptosis in JAK2V617F-positive cells. Mol Cancer Ther 2008; 7: 1176-1184.
    • (2008) Mol Cancer Ther , vol.7 , pp. 1176-1184
    • Lipka, D.B.1    Hoffmann, L.S.2    Heidel, F.3    Markova, B.4    Blum, M.C.5    Breitenbuecher, F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.