메뉴 건너뛰기




Volumn 111, Issue 10, 2008, Pages 5109-5117

Transgenic expression of JAK2V617F causes myeloproliferative disorders in mice

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROPOIETIN; JANUS KINASE 2; THROMBOPOIETIN; VAV PROTEIN;

EID: 46749137278     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2007-05-091579     Document Type: Article
Times cited : (173)

References (31)
  • 1
    • 25444483319 scopus 로고    scopus 로고
    • Myeloproliferative disorders: A practical review
    • Talarico LD. Myeloproliferative disorders: a practical review. Patient Care. 1998;30:37-57.
    • (1998) Patient Care , vol.30 , pp. 37-57
    • Talarico, L.D.1
  • 2
    • 0035449529 scopus 로고    scopus 로고
    • Classifying chronic myelomonocytic leukemia
    • Yavorkovsky LL, Cook P. Classifying chronic myelomonocytic leukemia. J Clin Oncol. 2001 ;19:3790-3792.
    • (2001) J Clin Oncol , vol.19 , pp. 3790-3792
    • Yavorkovsky, L.L.1    Cook, P.2
  • 3
    • 33845436745 scopus 로고    scopus 로고
    • The myeloproliferative disorders
    • Campbell PJ, Green AR. The myeloproliferative disorders. N Engl J Med. 2006:355:2452-2466.
    • (2006) N Engl J Med , vol.355 , pp. 2452-2466
    • Campbell, P.J.1    Green, A.R.2
  • 4
    • 0035810147 scopus 로고    scopus 로고
    • Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
    • Druker BJ, Talpaz M, Resta DJ, et al. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med. 2001;344:1031-1037.
    • (2001) N Engl J Med , vol.344 , pp. 1031-1037
    • Druker, B.J.1    Talpaz, M.2    Resta, D.J.3
  • 5
    • 20144363192 scopus 로고    scopus 로고
    • Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
    • Baxter EJ, Scott LM, Gampbell PJ, et al. Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders. Lancet. 2005;365:1054-1061.
    • (2005) Lancet , vol.365 , pp. 1054-1061
    • Baxter, E.J.1    Scott, L.M.2    Gampbell, P.J.3
  • 6
    • 20244369569 scopus 로고    scopus 로고
    • Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
    • Levine RL, Wadleigh M, Cools J, et al. Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell 2005;7:387-397.
    • (2005) Cancer Cell , vol.7 , pp. 387-397
    • Levine, R.L.1    Wadleigh, M.2    Cools, J.3
  • 7
    • 17844383458 scopus 로고    scopus 로고
    • A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
    • James C, Ugo V, Le Couedic JP, et al. A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature. 2005;434:1144-1148.
    • (2005) Nature , vol.434 , pp. 1144-1148
    • James, C.1    Ugo, V.2    Le Couedic, J.P.3
  • 8
    • 17644424955 scopus 로고    scopus 로고
    • A gain-of-function mutation of JAK2 in myeloproliferative disorders
    • Kralovics R, Passamonti F, Buser AS, et al. A gain-of-function mutation of JAK2 in myeloproliferative disorders. N Engl J Med. 2005;352:1779-1790.
    • (2005) N Engl J Med , vol.352 , pp. 1779-1790
    • Kralovics, R.1    Passamonti, F.2    Buser, A.S.3
  • 9
    • 20744460045 scopus 로고    scopus 로고
    • Identification of an acquired JAK2 mutation in polycythemia vera
    • Zhao R, Xing S, Li Z, et al. Identification of an acquired JAK2 mutation in polycythemia vera. J Biol Chem. 2005;280:22788-22792.
    • (2005) J Biol Chem , vol.280 , pp. 22788-22792
    • Zhao, R.1    Xing, S.2    Li, Z.3
  • 11
    • 33744490974 scopus 로고    scopus 로고
    • Expression of Jak2V617F causes a polycythemia vera-like disease with associated myelofibrosis in a murine bone marrow transplant model
    • Wernig G, MercherT, Okabe R, Levine RL, Lee BH, Gilliland DG. Expression of Jak2V617F causes a polycythemia vera-like disease with associated myelofibrosis in a murine bone marrow transplant model. Blood. 2006;107:4274-4281.
    • (2006) Blood , vol.107 , pp. 4274-4281
    • Wernig, G.1    Mercher, T.2    Okabe, R.3    Levine, R.L.4    Lee, B.H.5    Gilliland, D.G.6
  • 12
    • 33745721197 scopus 로고    scopus 로고
    • JAK2V617F expres-sion in murine hematopoietic cells leads to MPD mimicking human PV with secondary myelofibrosis
    • Lacout C, Pisani DF, Tulliez M, Gachelin FM, Vainchenker W, Villeval JL. JAK2V617F expres-sion in murine hematopoietic cells leads to MPD mimicking human PV with secondary myelofibrosis. Blood. 2006;108:1652-1660.
    • (2006) Blood , vol.108 , pp. 1652-1660
    • Lacout, C.1    Pisani, D.F.2    Tulliez, M.3    Gachelin, F.M.4    Vainchenker, W.5    Villeval, J.L.6
  • 13
    • 34447642422 scopus 로고    scopus 로고
    • Zaleskas VM, Krause DS, Lazarides K, et al. Molecular pathogenesis and therapy of polycythemia induced in mice by JAK2 V617F. PLoS ONE. 2006;1:e18.
    • Zaleskas VM, Krause DS, Lazarides K, et al. Molecular pathogenesis and therapy of polycythemia induced in mice by JAK2 V617F. PLoS ONE. 2006;1:e18.
  • 14
    • 33845798378 scopus 로고    scopus 로고
    • Characterization of murine JAK2V617F-positive myeloproliferative disease
    • Bumm TG, Elsea C, Corbin AS, et al. Characterization of murine JAK2V617F-positive myeloproliferative disease. Cancer Res. 2006;66:11156-11165.
    • (2006) Cancer Res , vol.66 , pp. 11156-11165
    • Bumm, T.G.1    Elsea, C.2    Corbin, A.S.3
  • 15
    • 21344440357 scopus 로고    scopus 로고
    • The JAK2 V617F activating tyrosine kinase mutation is an infrequent event in both "atypical" myeloproliferative disorders and the myeIodysplastic syndrome
    • Steensma DP, Dewald GW, Lasho TL, et al. The JAK2 V617F activating tyrosine kinase mutation is an infrequent event in both "atypical" myeloproliferative disorders and the myeIodysplastic syndrome. Blood. 2005;106:1207-1209.
    • (2005) Blood , vol.106 , pp. 1207-1209
    • Steensma, D.P.1    Dewald, G.W.2    Lasho, T.L.3
  • 16
    • 21344467318 scopus 로고    scopus 로고
    • Widespread occurrence of the JAK2 V617F mutation in chronic myeloproliferative disorders
    • Jones AV, Kreil S, Zoi K, et al. Widespread occurrence of the JAK2 V617F mutation in chronic myeloproliferative disorders. Blood. 2005:106:2162-2168.
    • (2005) Blood , vol.106 , pp. 2162-2168
    • Jones, A.V.1    Kreil, S.2    Zoi, K.3
  • 17
    • 27144466017 scopus 로고    scopus 로고
    • The V617F JAK2 mutation is uncommon in cancers and in myeloid malignancies other than the classic myeloproliferative disorders
    • Scott LM, Campbell PJ, Baxter EJ, et al. The V617F JAK2 mutation is uncommon in cancers and in myeloid malignancies other than the classic myeloproliferative disorders. Blood. 2005;106:2920-2921.
    • (2005) Blood , vol.106 , pp. 2920-2921
    • Scott, L.M.1    Campbell, P.J.2    Baxter, E.J.3
  • 19
    • 25844518265 scopus 로고    scopus 로고
    • The JAK2V617F activating mutation occurs in chronic myelomonocytic leukemia and acute myeloid leukemia, but not in acute lymphoblastic leukemia or chronic lymphocytic leukemia
    • Levine RL, Loriaux M, Huntly BJ, et al. The JAK2V617F activating mutation occurs in chronic myelomonocytic leukemia and acute myeloid leukemia, but not in acute lymphoblastic leukemia or chronic lymphocytic leukemia. Blood. 2005;106:3377-3379.
    • (2005) Blood , vol.106 , pp. 3377-3379
    • Levine, R.L.1    Loriaux, M.2    Huntly, B.J.3
  • 20
    • 33846012829 scopus 로고    scopus 로고
    • JAK2(V617F): Prevalence in a large Chinese hospital population
    • Xu X, Zhang Q, Luo J, et al. JAK2(V617F): prevalence in a large Chinese hospital population. Blood. 2007;109:339-342.
    • (2007) Blood , vol.109 , pp. 339-342
    • Xu, X.1    Zhang, Q.2    Luo, J.3
  • 21
    • 33845755386 scopus 로고    scopus 로고
    • Polycythemia vera is not initiated by JAK2V617F mutation
    • Nussenzveig RH, Swierczek SI, Jelinek J, et al. Polycythemia vera is not initiated by JAK2V617F mutation. Exp Hematol. 2007;35:32-38.
    • (2007) Exp Hematol , vol.35 , pp. 32-38
    • Nussenzveig, R.H.1    Swierczek, S.I.2    Jelinek, J.3
  • 22
    • 33947261202 scopus 로고    scopus 로고
    • In vitro expansion of erythroid progenitors from polycythemia vera patients leads to decrease in JAK2 V617F allele
    • Gaikwad A, Nussenzveig R, Liu E, Gottshalk S, Chang K, Prchal JT. In vitro expansion of erythroid progenitors from polycythemia vera patients leads to decrease in JAK2 V617F allele. Exp Hematol. 2007;35:587-595.
    • (2007) Exp Hematol , vol.35 , pp. 587-595
    • Gaikwad, A.1    Nussenzveig, R.2    Liu, E.3    Gottshalk, S.4    Chang, K.5    Prchal, J.T.6
  • 23
    • 0031962758 scopus 로고    scopus 로고
    • Transcriptional regulation of vav, a gene expressed throughout the hematopoietic compartment
    • Ogilvy S, Elefanty AG, Visvader J, Bath ML, Harris AW, Adams JM. Transcriptional regulation of vav, a gene expressed throughout the hematopoietic compartment. Blood. 1998;91:419-430.
    • (1998) Blood , vol.91 , pp. 419-430
    • Ogilvy, S.1    Elefanty, A.G.2    Visvader, J.3    Bath, M.L.4    Harris, A.W.5    Adams, J.M.6
  • 25
    • 33947541141 scopus 로고    scopus 로고
    • Erlotinib effectively inhibits JAK2V617F activity and polycythemia vera cell growth
    • Li Z, Xu M, Xing S, et al. Erlotinib effectively inhibits JAK2V617F activity and polycythemia vera cell growth. J Biol Chem. 2007;282:3428-3432.
    • (2007) J Biol Chem , vol.282 , pp. 3428-3432
    • Li, Z.1    Xu, M.2    Xing, S.3
  • 26
    • 35448951230 scopus 로고    scopus 로고
    • Characterization of a highly effective protein substrate for analysis of JAK2(V617F) activity
    • Li Z, Xing S, Wang S, Ho WT, Zhao ZJ. Characterization of a highly effective protein substrate for analysis of JAK2(V617F) activity. Exp Hematol. 2007;35:1624-1632.
    • (2007) Exp Hematol , vol.35 , pp. 1624-1632
    • Li, Z.1    Xing, S.2    Wang, S.3    Ho, W.T.4    Zhao, Z.J.5
  • 27
    • 33749358349 scopus 로고    scopus 로고
    • Progenitors homozygous for the V617F mutation occur in most patients with polycythemia vera, but not essential thrombocythemia
    • Scott LM, Scott MA, Campbell PJ, Green AR. Progenitors homozygous for the V617F mutation occur in most patients with polycythemia vera, but not essential thrombocythemia. Blood. 2006;108:2435-2437.
    • (2006) Blood , vol.108 , pp. 2435-2437
    • Scott, L.M.1    Scott, M.A.2    Campbell, P.J.3    Green, A.R.4
  • 28
    • 34547953018 scopus 로고    scopus 로고
    • Clinical profile of homozygous JAK2V617F mutation in patients with polycythemia vera or essential thrombocythemia
    • Vannucchi AM, Antonioli E, Guglielmelli P, et al. Clinical profile of homozygous JAK2V617F mutation in patients with polycythemia vera or essential thrombocythemia. Blood. 2007;110:840-846.
    • (2007) Blood , vol.110 , pp. 840-846
    • Vannucchi, A.M.1    Antonioli, E.2    Guglielmelli, P.3
  • 29
    • 36248991883 scopus 로고    scopus 로고
    • The JAK2 V617F allele burden in essential thrombocythemia, polycythemia vera and primary myelofibrosis: Impact on disease phenotype
    • Larsen TS, Pallisgaard N, Møller MB, Hassel-balch HC. The JAK2 V617F allele burden in essential thrombocythemia, polycythemia vera and primary myelofibrosis: impact on disease phenotype. Eur J Haematol. 2007;79:508-515.
    • (2007) Eur J Haematol , vol.79 , pp. 508-515
    • Larsen, T.S.1    Pallisgaard, N.2    Møller, M.B.3    Hassel-balch, H.C.4
  • 30
    • 38349035684 scopus 로고    scopus 로고
    • Shide K, Shimoda HK, Kumano T, et al. Development of ET, primary myelofibrosis and PV in mice expressing JAK2 V617F. Leukemia. 200822:87-95.
    • Shide K, Shimoda HK, Kumano T, et al. Development of ET, primary myelofibrosis and PV in mice expressing JAK2 V617F. Leukemia. 200822:87-95.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.