Acquired uniparental disomy of chromosome 9p is a frequent stem cell defect in polycythemia vera

Experimental Hematology

Volumn 30, Issue 3, 2002, Pages 229-236

  Kralovics, Robert ^a,b   Guan, Yongli ^a   Prchal, Josef T ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; BONE MARROW CELL; CELL CLONING; CELL LINE; CHROMOSOME 10Q; CHROMOSOME 11Q; CHROMOSOME 9P; CHROMOSOME ANALYSIS; CONTROLLED STUDY; GENE EXPRESSION; GENE IDENTIFICATION; GENE OVEREXPRESSION; GENE SEQUENCE; GENETIC SCREENING; GENETIC TRANSFECTION; GRANULOCYTE; HEMATOPOIESIS; HUMAN; HUMAN CELL; LYMPHOID CELL; MITOTIC RECOMBINATION; POLYCYTHEMIA VERA; PRIORITY JOURNAL; PROTEIN ANALYSIS; SEQUENCE ANALYSIS; STEM CELL; UNIPARENTAL DISOMY;

ANIMALS; ANTIGENS, CD34; CARRIER PROTEINS; CHROMOSOMES, HUMAN, PAIR 10; CHROMOSOMES, HUMAN, PAIR 11; CHROMOSOMES, HUMAN, PAIR 9; DNA MUTATIONAL ANALYSIS; DRUG RESISTANCE; GENE EXPRESSION; GENES, P16; HEMATOPOIETIC STEM CELLS; HUMANS; LOSS OF HETEROZYGOSITY; MICE; MUTATION; NFI TRANSCRIPTION FACTORS; POLYCYTHEMIA VERA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTION FACTORS; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA; UNIPARENTAL DISOMY;

EID: 0036191941     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-472X(01)00789-5     Document Type: Article

References (22)

1. Polycythemia vera: Stem-cell and probable clonal origin of the disease
2. Clonal stability of blood cell lineages indicated by X-chromosomal transcriptional polymorphism
3. Chromosome studies in 104 patients with polycythemia vera
4. Molecular genetics and cytogenetics of myeloproliferative disorders
5. Letter: Bone-marrow responses in polycythemia vera
6. Polycythemia vera. The in vitro response of normal and abnormal stem cell lines to erythropoietin
7. Identification of increased protein tyrosine phosphatase activity in polycythemia vera erythroid progenitor cells
8. Defective expression of the SHP-1 phosphatase in polycythemia vera
9. Impaired expression of the thrombopoietin receptor by platelets from patients with polycythemia vera
10. Expression of bcl-x in erythroid precursors from patients with polycythemia vera
11. Cloning of PRV-1, a novel member of the uPAR receptor superfamily, which is overexpressed in polycythemia rubra vera
12. Increased expression of the INK4a/ARF locus in polycythemia vera
13. Familial polycythemia vera: Mode of inheritance, clonality, and genetic analysis of candidate genes and chromosomal regions
14. Rapid determination of clonality by detection of two closely linked X-chromosome exonic polymorphisms using allele-specific PCR
15. A polymorphism of the X-linked gene IDS increases the number of females informative for transcriptional clonality assays
16. Expression of five selected human mismatch repair genes simultaneously detected in normal and cancer cell lines by a nonradioactive multiplex reverse transcription polymerase chain reaction
17. p53-independent role of MDM2 in TGF-β1 resistance
18. Transcriptional analysis of the active X-chromosome in normal and clonal hematopoiesis
19. Hypermethylation of the p15INK4B gene in myelodysplastic syndromes
20. Two regions of deletion in 9p23-24 in sporadic breast cancer
21. Disruption of the murine nuclear factor I-A gene (Nfia) results in perinatal lethality, hydrocephalus, and agenesis of the corpus callosum
22. Roles of the NFI/CTF gene family in transcription and development