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Volumn 11, Issue 7, 2009, Pages 665-679

Obesity, serious mental illness and antipsychotic drugs

Author keywords

Aetiology; Antipsychotic; Bipolar illness; Obesity; Schizophrenia

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; ARIPIPRAZOLE; ATYPICAL ANTIPSYCHOTIC AGENT; BETA 3 ADRENERGIC RECEPTOR; BETAHISTINE; CHLORPROMAZINE; CLOZAPINE; CYTOKINE; GHRELIN; GLUCOCORTICOID; HALOPERIDOL; HISTAMINE H1 RECEPTOR; HORMONE; LEPTIN; MELANOCORTIN 4 RECEPTOR; MIFEPRISTONE; NEUROLEPTIC AGENT; NEUROPEPTIDE Y; NEUROTRANSMITTER; OLANZAPINE; PLACEBO; QUETIAPINE; RISPERIDONE; SEROTONIN 2C RECEPTOR; ZIPRASIDONE;

EID: 70349194825     PISSN: 14628902     EISSN: 14631326     Source Type: Journal    
DOI: 10.1111/j.1463-1326.2009.01038.x     Document Type: Review
Times cited : (114)

References (185)
  • 1
    • 1642405087 scopus 로고    scopus 로고
    • The obesity epidemic, metabolic syndrome and future prevention strategies
    • James PT, Rigby N, Leach R. The obesity epidemic, metabolic syndrome and future prevention strategies. Eur J Cardiovasc Prev Rehabil 2004, 11:3-8.
    • (2004) Eur J Cardiovasc Prev Rehabil , vol.11 , pp. 3-8
    • James, P.T.1    Rigby, N.2    Leach, R.3
  • 5
    • 0036607520 scopus 로고    scopus 로고
    • Changes in body mass index for individuals with and without schizophrenia, 1987-1996
    • Homel P, Casey D, Allison DB. Changes in body mass index for individuals with and without schizophrenia, 1987-1996. Schizophr Res 2002, 55:277-284.
    • (2002) Schizophr Res , vol.55 , pp. 277-284
    • Homel, P.1    Casey, D.2    Allison, D.B.3
  • 6
    • 27744502054 scopus 로고    scopus 로고
    • Prevalence of the metabolic syndrome in patients with schizophrenia: baseline results from the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) schizophrenia trial and comparison with national estimates from NHANES III
    • McEvoy JP, Meyer JM, Goff DC. Prevalence of the metabolic syndrome in patients with schizophrenia: baseline results from the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) schizophrenia trial and comparison with national estimates from NHANES III. Schizophr Res 2005, 80:19-32.
    • (2005) Schizophr Res , vol.80 , pp. 19-32
    • McEvoy, J.P.1    Meyer, J.M.2    Goff, D.C.3    et al4
  • 7
    • 33947213594 scopus 로고    scopus 로고
    • Long-term maintenance of weight loss in patients with severe mental illness through a behavioural treatment programme in the UK
    • Pendlebury J, Bushe CJ, Wildgust HJ, Holt RI. Long-term maintenance of weight loss in patients with severe mental illness through a behavioural treatment programme in the UK. Acta Psychiatr Scand 2007, 115:286-294.
    • (2007) Acta Psychiatr Scand , vol.115 , pp. 286-294
    • Pendlebury, J.1    Bushe, C.J.2    Wildgust, H.J.3    Holt, R.I.4
  • 8
    • 0034782477 scopus 로고    scopus 로고
    • Prevalence of obesity in adolescent and young adult patients with and without schizophrenia and in relationship to antipsychotic medication
    • Theisen FM, Linden A, Geller F. Prevalence of obesity in adolescent and young adult patients with and without schizophrenia and in relationship to antipsychotic medication. J Psychiatr Res 2001, 35:339-345.
    • (2001) J Psychiatr Res , vol.35 , pp. 339-345
    • Theisen, F.M.1    Linden, A.2    Geller, F.3    et al4
  • 10
    • 33747398701 scopus 로고    scopus 로고
    • Olanzapine and haloperidol in first episode psychosis: two-year data
    • Green AI, Lieberman JA, Hamer RM. Olanzapine and haloperidol in first episode psychosis: two-year data. Schizophr Res 2006, 86:234-243.
    • (2006) Schizophr Res , vol.86 , pp. 234-243
    • Green, A.I.1    Lieberman, J.A.2    Hamer, R.M.3    et al4
  • 11
    • 0037712923 scopus 로고    scopus 로고
    • Atypical and conventional antipsychotic drugs in treatment-naive first-episode schizophrenia: a 52-week randomized trial of clozapine vs chlorpromazine
    • Lieberman JA, Phillips M, Gu H. Atypical and conventional antipsychotic drugs in treatment-naive first-episode schizophrenia: a 52-week randomized trial of clozapine vs chlorpromazine. Neuropsychopharmacology 2003, 28:995-1003.
    • (2003) Neuropsychopharmacology , vol.28 , pp. 995-1003
    • Lieberman, J.A.1    Phillips, M.2    Gu, H.3    et al4
  • 12
    • 0032977072 scopus 로고    scopus 로고
    • The unhealthy lifestyle of people with schizophrenia
    • Brown S, Birtwistle J, Roe L, Thompson C. The unhealthy lifestyle of people with schizophrenia. Psychol Med 1999, 29:697-701.
    • (1999) Psychol Med , vol.29 , pp. 697-701
    • Brown, S.1    Birtwistle, J.2    Roe, L.3    Thompson, C.4
  • 13
    • 0024892110 scopus 로고
    • Physical health of the long-term mentally ill in the community. Is there unmet need?
    • Brugha TS, Wing JK, Smith BL. Physical health of the long-term mentally ill in the community. Is there unmet need?. Br J Psychiatry 1989, 155:777-781.
    • (1989) Br J Psychiatry , vol.155 , pp. 777-781
    • Brugha, T.S.1    Wing, J.K.2    Smith, B.L.3
  • 14
    • 0029994207 scopus 로고    scopus 로고
    • Cardiovascular and respiratory risk factors and symptoms among general practice patients with long-term mental illness
    • Kendrick T. Cardiovascular and respiratory risk factors and symptoms among general practice patients with long-term mental illness. Br J Psychiatry 1996, 169:733-739.
    • (1996) Br J Psychiatry , vol.169 , pp. 733-739
    • Kendrick, T.1
  • 15
    • 0032929794 scopus 로고    scopus 로고
    • The distribution of body mass index among individuals with and without schizophrenia
    • Allison DB, Fontaine KR, Heo M. The distribution of body mass index among individuals with and without schizophrenia. J Clin Psychiatry 1999, 60:215-220.
    • (1999) J Clin Psychiatry , vol.60 , pp. 215-220
    • Allison, D.B.1    Fontaine, K.R.2    Heo, M.3    et al4
  • 16
    • 0020407036 scopus 로고
    • The body composition of the chronic mentally ill
    • Morgan DB, Hullin RP. The body composition of the chronic mentally ill. Hum Nutr Clin Nutr 1982, 36:439-448.
    • (1982) Hum Nutr Clin Nutr , vol.36 , pp. 439-448
    • Morgan, D.B.1    Hullin, R.P.2
  • 17
    • 85047696552 scopus 로고    scopus 로고
    • Increased visceral fat distribution in drug-naive and drug-free patients with schizophrenia
    • Thakore JH, Mann JN, Vlahos I, Martin A, Reznek R. Increased visceral fat distribution in drug-naive and drug-free patients with schizophrenia. Int J Obes Relat Metab Disord 2002, 26:137-141.
    • (2002) Int J Obes Relat Metab Disord , vol.26 , pp. 137-141
    • Thakore, J.H.1    Mann, J.N.2    Vlahos, I.3    Martin, A.4    Reznek, R.5
  • 18
    • 0346373688 scopus 로고    scopus 로고
    • Effects of antipsychotics on fat deposition and changes in leptin and insulin levels. Magnetic resonance imaging study of previously untreated people with schizophrenia
    • Zhang ZJ, Yao ZJ, Liu W, Fang Q, Reynolds GP. Effects of antipsychotics on fat deposition and changes in leptin and insulin levels. Magnetic resonance imaging study of previously untreated people with schizophrenia. Br J Psychiatry 2004, 184:58-62.
    • (2004) Br J Psychiatry , vol.184 , pp. 58-62
    • Zhang, Z.J.1    Yao, Z.J.2    Liu, W.3    Fang, Q.4    Reynolds, G.P.5
  • 19
    • 39049127051 scopus 로고    scopus 로고
    • Hepatic insulin resistance in antipsychotic naive schizophrenic patients: stable isotope studies of glucose metabolism
    • van Nimwegen LJ, Storosum JG, Blumer RM. Hepatic insulin resistance in antipsychotic naive schizophrenic patients: stable isotope studies of glucose metabolism. J Clin Endocrinol Metab 2008, 93:572-577.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 572-577
    • van Nimwegen, L.J.1    Storosum, J.G.2    Blumer, R.M.3    et al4
  • 20
    • 0028917432 scopus 로고
    • Weight gain as a risk factor for clinical diabetes mellitus in women
    • Colditz GA, Willett WC, Rotnitzky A, Manson JE. Weight gain as a risk factor for clinical diabetes mellitus in women. Ann Intern Med 1995, 122:481-486.
    • (1995) Ann Intern Med , vol.122 , pp. 481-486
    • Colditz, G.A.1    Willett, W.C.2    Rotnitzky, A.3    Manson, J.E.4
  • 24
    • 0030843960 scopus 로고    scopus 로고
    • Genetic and environmental factors in relative body weight and human adiposity
    • Maes HH, Neale MC, Eaves LJ. Genetic and environmental factors in relative body weight and human adiposity. Behav Genet 1997, 27:325-351.
    • (1997) Behav Genet , vol.27 , pp. 325-351
    • Maes, H.H.1    Neale, M.C.2    Eaves, L.J.3
  • 25
    • 33845567553 scopus 로고    scopus 로고
    • Genetics of obesity in humans
    • Farooqi S, O'Rahilly S. Genetics of obesity in humans. Endocr Rev 2006, 27:710-718.
    • (2006) Endocr Rev , vol.27 , pp. 710-718
    • Farooqi, S.1    O'Rahilly, S.2
  • 26
    • 34248594090 scopus 로고    scopus 로고
    • A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
    • Frayling TM, Timpson NJ, Weedon MN. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 2007, 316:889-894.
    • (2007) Science , vol.316 , pp. 889-894
    • Frayling, T.M.1    Timpson, N.J.2    Weedon, M.N.3    et al4
  • 27
    • 44349142294 scopus 로고    scopus 로고
    • Common variants near MC4R are associated with fat mass, weight and risk of obesity
    • Loos RJ, Lindgren CM, Li S. Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet 2008, 40:768-775.
    • (2008) Nat Genet , vol.40 , pp. 768-775
    • Loos, R.J.1    Lindgren, C.M.2    Li, S.3    et al4
  • 29
    • 34548493015 scopus 로고    scopus 로고
    • Neurotransmitters in key neurons of the hypothalamus that regulate feeding behavior and body weight
    • Meister B. Neurotransmitters in key neurons of the hypothalamus that regulate feeding behavior and body weight. Physiol Behav 2007, 92:263-271.
    • (2007) Physiol Behav , vol.92 , pp. 263-271
    • Meister, B.1
  • 30
    • 0036288345 scopus 로고    scopus 로고
    • Neither agouti-related protein nor neuropeptide Y is critically required for the regulation of energy homeostasis in mice
    • Qian S, Chen H, Weingarth D. Neither agouti-related protein nor neuropeptide Y is critically required for the regulation of energy homeostasis in mice. Mol Cell Biol 2002, 22:5027-5035.
    • (2002) Mol Cell Biol , vol.22 , pp. 5027-5035
    • Qian, S.1    Chen, H.2    Weingarth, D.3    et al4
  • 31
    • 0030889192 scopus 로고    scopus 로고
    • Targeted disruption of the melanocortin-4 receptor results in obesity in mice
    • Huszar D, Lynch CA, Fairchild-Huntress V. Targeted disruption of the melanocortin-4 receptor results in obesity in mice. Cell 1997, 88:131-141.
    • (1997) Cell , vol.88 , pp. 131-141
    • Huszar, D.1    Lynch, C.A.2    Fairchild-Huntress, V.3    et al4
  • 32
    • 34548473376 scopus 로고    scopus 로고
    • Appetite signaling: from gut peptides and enteric nerves to brain
    • Naslund E, Hellstrom PM. Appetite signaling: from gut peptides and enteric nerves to brain. Physiol Behav 2007, 92:256-262.
    • (2007) Physiol Behav , vol.92 , pp. 256-262
    • Naslund, E.1    Hellstrom, P.M.2
  • 34
    • 0035843183 scopus 로고    scopus 로고
    • A role for ghrelin in the central regulation of feeding
    • Nakazato M, Murakami N, Date Y. A role for ghrelin in the central regulation of feeding. Nature 2001, 409:194-198.
    • (2001) Nature , vol.409 , pp. 194-198
    • Nakazato, M.1    Murakami, N.2    Date, Y.3    et al4
  • 35
    • 34247853485 scopus 로고    scopus 로고
    • The adipocyte as an active participant in energy balance and metabolism
    • Badman MK, Flier JS. The adipocyte as an active participant in energy balance and metabolism. Gastroenterology 2007, 132:2103-2115.
    • (2007) Gastroenterology , vol.132 , pp. 2103-2115
    • Badman, M.K.1    Flier, J.S.2
  • 36
    • 0030878110 scopus 로고    scopus 로고
    • Congenital leptin deficiency is associated with severe early-onset obesity in humans
    • Montague CT, Farooqi IS, Whitehead JP. Congenital leptin deficiency is associated with severe early-onset obesity in humans. Nature 1997, 387:903-908.
    • (1997) Nature , vol.387 , pp. 903-908
    • Montague, C.T.1    Farooqi, I.S.2    Whitehead, J.P.3    et al4
  • 37
    • 0344450708 scopus 로고    scopus 로고
    • A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction
    • Clement K, Vaisse C, Lahlou N. A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction. Nature 1998, 392:398-401.
    • (1998) Nature , vol.392 , pp. 398-401
    • Clement, K.1    Vaisse, C.2    Lahlou, N.3    et al4
  • 38
    • 0034687376 scopus 로고    scopus 로고
    • Ghrelin induces adiposity in rodents
    • Tschop M, Smiley DL, Heiman ML. Ghrelin induces adiposity in rodents. Nature 2000, 407:908-913.
    • (2000) Nature , vol.407 , pp. 908-913
    • Tschop, M.1    Smiley, D.L.2    Heiman, M.L.3
  • 39
    • 3242796577 scopus 로고    scopus 로고
    • Is susceptibility to weight gain characterized by homeostatic or hedonic risk factors for overconsumption?
    • Blundell JE, Finlayson G. Is susceptibility to weight gain characterized by homeostatic or hedonic risk factors for overconsumption?. Physiol Behav 2004, 82:21-25.
    • (2004) Physiol Behav , vol.82 , pp. 21-25
    • Blundell, J.E.1    Finlayson, G.2
  • 41
    • 33748786233 scopus 로고    scopus 로고
    • Food intake and reward mechanisms in patients with schizophrenia: implications for metabolic disturbances and treatment with second-generation antipsychotic agents
    • Elman I, Borsook D, Lukas SE. Food intake and reward mechanisms in patients with schizophrenia: implications for metabolic disturbances and treatment with second-generation antipsychotic agents. Neuropsychopharmacology 2006, 31:2091-2120.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 2091-2120
    • Elman, I.1    Borsook, D.2    Lukas, S.E.3
  • 42
    • 33845541048 scopus 로고    scopus 로고
    • Attenuation of insulin-evoked responses in brain networks controlling appetite and reward in insulin resistance: the cerebral basis for impaired control of food intake in metabolic syndrome?
    • Anthony K, Reed LJ, Dunn JT. Attenuation of insulin-evoked responses in brain networks controlling appetite and reward in insulin resistance: the cerebral basis for impaired control of food intake in metabolic syndrome?. Diabetes 2006, 55:2986-2992.
    • (2006) Diabetes , vol.55 , pp. 2986-2992
    • Anthony, K.1    Reed, L.J.2    Dunn, J.T.3    et al4
  • 43
    • 34548050674 scopus 로고    scopus 로고
    • Understanding metabolic homeostasis and imbalance: what is the role of the endocannabinoid system?
    • Kunos G. Understanding metabolic homeostasis and imbalance: what is the role of the endocannabinoid system?. Am J Med 2007, 120(9 Suppl. 1):S18-S24.
    • (2007) Am J Med , vol.120 , Issue.9 SUPPL. 1
    • Kunos, G.1
  • 44
    • 0032547558 scopus 로고    scopus 로고
    • Dietary intake of schizophrenic patients in Nithsdale, Scotland: case-control study
    • McCreadie R, Macdonald E, Blacklock C. Dietary intake of schizophrenic patients in Nithsdale, Scotland: case-control study. BMJ 1998, 317:784-785.
    • (1998) BMJ , vol.317 , pp. 784-785
    • McCreadie, R.1    Macdonald, E.2    Blacklock, C.3    et al4
  • 46
    • 17844365325 scopus 로고    scopus 로고
    • Urbanisation and health
    • Godfrey R, Julien M. Urbanisation and health. Clin Med 2005, 5:137-141.
    • (2005) Clin Med , vol.5 , pp. 137-141
    • Godfrey, R.1    Julien, M.2
  • 48
    • 33646103388 scopus 로고    scopus 로고
    • Clustering of metabolic comorbidity in schizophrenia: a genetic contribution?
    • Gough SC, O' Donovan MC. Clustering of metabolic comorbidity in schizophrenia: a genetic contribution?. J Psychopharmacol 2005, 19(6 Suppl):47-55.
    • (2005) J Psychopharmacol , vol.19 , Issue.6 SUPPL , pp. 47-55
    • Gough, S.C.1    O' Donovan, M.C.2
  • 49
    • 33845472259 scopus 로고    scopus 로고
    • Resting metabolic rate and respiratory quotient: results from a genome-wide scan in the Quebec Family Study
    • Jacobson P, Rankinen T, Tremblay A, Perusse L, Chagnon YC, Bouchard C. Resting metabolic rate and respiratory quotient: results from a genome-wide scan in the Quebec Family Study. Am J Clin Nutr 2006, 84:1527-1533.
    • (2006) Am J Clin Nutr , vol.84 , pp. 1527-1533
    • Jacobson, P.1    Rankinen, T.2    Tremblay, A.3    Perusse, L.4    Chagnon, Y.C.5    Bouchard, C.6
  • 50
    • 33745092183 scopus 로고    scopus 로고
    • Differences in resting energy expenditure and body composition between patients with schizophrenia and healthy controls
    • Nilsson BM, Forslund AH, Olsson RM, Hambraeus L, Wiesel FA. Differences in resting energy expenditure and body composition between patients with schizophrenia and healthy controls. Acta Psychiatr Scand 2006, 114:27-35.
    • (2006) Acta Psychiatr Scand , vol.114 , pp. 27-35
    • Nilsson, B.M.1    Forslund, A.H.2    Olsson, R.M.3    Hambraeus, L.4    Wiesel, F.A.5
  • 51
    • 15944391388 scopus 로고    scopus 로고
    • Resting energy expenditure is lower than predicted in people taking atypical antipsychotic medication
    • Sharpe JK, Byrne NM, Stedman TJ, Hills AP. Resting energy expenditure is lower than predicted in people taking atypical antipsychotic medication. J Am Diet Assoc 2005, 105:612-615.
    • (2005) J Am Diet Assoc , vol.105 , pp. 612-615
    • Sharpe, J.K.1    Byrne, N.M.2    Stedman, T.J.3    Hills, A.P.4
  • 52
    • 35748972057 scopus 로고    scopus 로고
    • Measured and expected resting energy expenditure in patients with bipolar disorder on maintenance treatment
    • Soreca I, Mauri M, Castrogiovanni S, Simoncini M, Cassano GB. Measured and expected resting energy expenditure in patients with bipolar disorder on maintenance treatment. Bipolar Disord 2007, 9:784-788.
    • (2007) Bipolar Disord , vol.9 , pp. 784-788
    • Soreca, I.1    Mauri, M.2    Castrogiovanni, S.3    Simoncini, M.4    Cassano, G.B.5
  • 53
    • 24344463527 scopus 로고    scopus 로고
    • Fetal programming of body composition and musculoskeletal development
    • Sayer AA, Cooper C. Fetal programming of body composition and musculoskeletal development. Early Hum Dev 2005, 81:735-744.
    • (2005) Early Hum Dev , vol.81 , pp. 735-744
    • Sayer, A.A.1    Cooper, C.2
  • 54
    • 3042821955 scopus 로고    scopus 로고
    • Birth weight, weight at 1 y of age, and body composition in older men: findings from the Hertfordshire Cohort Study
    • Sayer AA, Syddall HE, Dennison EM. Birth weight, weight at 1 y of age, and body composition in older men: findings from the Hertfordshire Cohort Study. Am J Clin Nutr 2004, 80:199-203.
    • (2004) Am J Clin Nutr , vol.80 , pp. 199-203
    • Sayer, A.A.1    Syddall, H.E.2    Dennison, E.M.3    et al4
  • 55
    • 0038343015 scopus 로고    scopus 로고
    • The influence of birthweight and intrauterine environment on adiposity and fat distribution in later life
    • Rogers I. The influence of birthweight and intrauterine environment on adiposity and fat distribution in later life. Int J Obes Relat Metab Disord 2003, 27:755-777.
    • (2003) Int J Obes Relat Metab Disord , vol.27 , pp. 755-777
    • Rogers, I.1
  • 56
    • 0026496482 scopus 로고
    • Schizophrenia after prenatal exposure to the Dutch Hunger Winter of 1944-1945
    • Susser ES, Lin SP. Schizophrenia after prenatal exposure to the Dutch Hunger Winter of 1944-1945. Arch Gen Psychiatry 1992, 49:983-988.
    • (1992) Arch Gen Psychiatry , vol.49 , pp. 983-988
    • Susser, E.S.1    Lin, S.P.2
  • 57
    • 42949100803 scopus 로고    scopus 로고
    • The hypothalamic-pituitary-adrenal-axis in the regulation of energy balance
    • Nieuwenhuizen AG, Rutters F. The hypothalamic-pituitary-adrenal-axis in the regulation of energy balance. Physiol Behav 2008, 94:169-177.
    • (2008) Physiol Behav , vol.94 , pp. 169-177
    • Nieuwenhuizen, A.G.1    Rutters, F.2
  • 58
    • 0029972402 scopus 로고    scopus 로고
    • The regulation of adipose tissue distribution in humans
    • Bjorntorp P. The regulation of adipose tissue distribution in humans. Int J Obes Relat Metab Disord 1996, 20:291-302.
    • (1996) Int J Obes Relat Metab Disord , vol.20 , pp. 291-302
    • Bjorntorp, P.1
  • 59
    • 0024854194 scopus 로고
    • The effects of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency
    • Salomon F, Cuneo RC, Hesp R, Sonksen PH. The effects of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency. N Engl J Med 1989, 321:1797-1803.
    • (1989) N Engl J Med , vol.321 , pp. 1797-1803
    • Salomon, F.1    Cuneo, R.C.2    Hesp, R.3    Sonksen, P.H.4
  • 60
    • 4444251446 scopus 로고    scopus 로고
    • Understanding schizophrenia and diabetes
    • Dinan T, Peveler R, Holt R. Understanding schizophrenia and diabetes. Hosp Med 2004, 65:485-488.
    • (2004) Hosp Med , vol.65 , pp. 485-488
    • Dinan, T.1    Peveler, R.2    Holt, R.3
  • 61
    • 35748971041 scopus 로고    scopus 로고
    • Insulin and insulin-like growth factor-1 abnormalities in antipsychotic-naive schizophrenia
    • Venkatasubramanian G, Chittiprol S, Neelakantachar N. Insulin and insulin-like growth factor-1 abnormalities in antipsychotic-naive schizophrenia. Am J Psychiatry 2007, 164:1557-1560.
    • (2007) Am J Psychiatry , vol.164 , pp. 1557-1560
    • Venkatasubramanian, G.1    Chittiprol, S.2    Neelakantachar, N.3    et al4
  • 63
    • 0031762908 scopus 로고    scopus 로고
    • Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: depot difference and regulation by glucocorticoid
    • Fried SK, Bunkin DA, Greenberg AS. Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: depot difference and regulation by glucocorticoid. J Clin Endocrinol Metab 1998, 83:847-850.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 847-850
    • Fried, S.K.1    Bunkin, D.A.2    Greenberg, A.S.3
  • 64
    • 33646002942 scopus 로고    scopus 로고
    • Smoldering systemic inflammation: a link between schizophrenia, smoking and obesity
    • Justo D. Smoldering systemic inflammation: a link between schizophrenia, smoking and obesity. Acta Psychiatr Scand 2006, 113:245-246.
    • (2006) Acta Psychiatr Scand , vol.113 , pp. 245-246
    • Justo, D.1
  • 65
    • 0141832614 scopus 로고    scopus 로고
    • Relationship of depression to diabetes types 1 and 2: epidemiology, biology, and treatment
    • Musselman DL, Betan E, Larsen H, Phillips LS. Relationship of depression to diabetes types 1 and 2: epidemiology, biology, and treatment. Biol Psychiatry 2003, 54:317-329.
    • (2003) Biol Psychiatry , vol.54 , pp. 317-329
    • Musselman, D.L.1    Betan, E.2    Larsen, H.3    Phillips, L.S.4
  • 66
    • 33646681652 scopus 로고    scopus 로고
    • A 24-week randomized study of olanzapine versus ziprasidone in the treatment of schizophrenia or schizoaffective disorder in patients with prominent depressive symptoms
    • Kinon BJ, Lipkovich I, Edwards SB, Adams DH, Ascher-Svanum H, Siris SG. A 24-week randomized study of olanzapine versus ziprasidone in the treatment of schizophrenia or schizoaffective disorder in patients with prominent depressive symptoms. J Clin Psychopharmacol 2006, 26:157-162.
    • (2006) J Clin Psychopharmacol , vol.26 , pp. 157-162
    • Kinon, B.J.1    Lipkovich, I.2    Edwards, S.B.3    Adams, D.H.4    Ascher-Svanum, H.5    Siris, S.G.6
  • 67
    • 34147185609 scopus 로고    scopus 로고
    • Metabolic control in patients with schizophrenia treated with amisulpride or olanzapine
    • Peuskens J, De Hert M, Mortimer A. Metabolic control in patients with schizophrenia treated with amisulpride or olanzapine. Int Clin Psychopharmacol 2007, 22:145-152.
    • (2007) Int Clin Psychopharmacol , vol.22 , pp. 145-152
    • Peuskens, J.1    De Hert, M.2    Mortimer, A.3
  • 68
    • 16644402581 scopus 로고    scopus 로고
    • A comparison of weight change during treatment with olanzapine or aripiprazole: results from a randomized, double-blind study
    • McQuade RD, Stock E, Marcus R. A comparison of weight change during treatment with olanzapine or aripiprazole: results from a randomized, double-blind study. J Clin Psychiatry 2004, 65(Suppl. 18):47-56.
    • (2004) J Clin Psychiatry , vol.65 , Issue.SUPPL. 18 , pp. 47-56
    • McQuade, R.D.1    Stock, E.2    Marcus, R.3    et al4
  • 69
    • 26444456116 scopus 로고    scopus 로고
    • Olanzapine versus ziprasidone: results of a 28-week double-blind study in patients with schizophrenia
    • Breier A, Berg PH, Thakore JH. Olanzapine versus ziprasidone: results of a 28-week double-blind study in patients with schizophrenia. Am J Psychiatry 2005, 162:1879-1887.
    • (2005) Am J Psychiatry , vol.162 , pp. 1879-1887
    • Breier, A.1    Berg, P.H.2    Thakore, J.H.3    et al4
  • 70
    • 0344033647 scopus 로고    scopus 로고
    • A double-blind, randomized, placebo-controlled trial of olanzapine in the prevention of psychotic relapse
    • Beasley CM, Sutton VK, Hamilton SH. A double-blind, randomized, placebo-controlled trial of olanzapine in the prevention of psychotic relapse. J Clin Psychopharmacol 2003, 23:582-594.
    • (2003) J Clin Psychopharmacol , vol.23 , pp. 582-594
    • Beasley, C.M.1    Sutton, V.K.2    Hamilton, S.H.3    et al4
  • 71
    • 0345293130 scopus 로고    scopus 로고
    • Effectiveness and cost of olanzapine and haloperidol in the treatment of schizophrenia: a randomized controlled trial
    • Rosenheck R, Perlick D, Bingham S. Effectiveness and cost of olanzapine and haloperidol in the treatment of schizophrenia: a randomized controlled trial. JAMA 2003, 290:2693-2702.
    • (2003) JAMA , vol.290 , pp. 2693-2702
    • Rosenheck, R.1    Perlick, D.2    Bingham, S.3    et al4
  • 72
    • 33750614310 scopus 로고    scopus 로고
    • Effectiveness of long-term aripiprazole therapy in patients with acutely relapsing or chronic, stable schizophrenia: a 52-week, open-label comparison with olanzapine
    • Chrzanowski WK, Marcus RN, Torbeyns A, Nyilas M, McQuade RD. Effectiveness of long-term aripiprazole therapy in patients with acutely relapsing or chronic, stable schizophrenia: a 52-week, open-label comparison with olanzapine. Psychopharmacology 2006, 189:259-266.
    • (2006) Psychopharmacology , vol.189 , pp. 259-266
    • Chrzanowski, W.K.1    Marcus, R.N.2    Torbeyns, A.3    Nyilas, M.4    McQuade, R.D.5
  • 73
    • 21344437952 scopus 로고    scopus 로고
    • Olanzapine versus lithium in the maintenance treatment of bipolar disorder: a 12-month, randomized, double-blind, controlled clinical trial
    • Tohen M, Greil W, Calabrese JR. Olanzapine versus lithium in the maintenance treatment of bipolar disorder: a 12-month, randomized, double-blind, controlled clinical trial. Am J Psychiatry 2005, 162:1281-1290.
    • (2005) Am J Psychiatry , vol.162 , pp. 1281-1290
    • Tohen, M.1    Greil, W.2    Calabrese, J.R.3    et al4
  • 74
    • 11144354711 scopus 로고    scopus 로고
    • Relapse prevention in bipolar I disorder: 18-month comparison of olanzapine plus mood stabiliser v. mood stabiliser alone
    • Tohen M, Chengappa KN, Suppes T. Relapse prevention in bipolar I disorder: 18-month comparison of olanzapine plus mood stabiliser v. mood stabiliser alone. Br J Psychiatry 2004, 184:337-345.
    • (2004) Br J Psychiatry , vol.184 , pp. 337-345
    • Tohen, M.1    Chengappa, K.N.2    Suppes, T.3    et al4
  • 75
    • 34547218869 scopus 로고    scopus 로고
    • Efficacy and tolerability of olanzapine, quetiapine, and risperidone in the treatment of early psychosis: a randomized, double-blind 52-week comparison
    • McEvoy JP, Lieberman JA, Perkins DO. Efficacy and tolerability of olanzapine, quetiapine, and risperidone in the treatment of early psychosis: a randomized, double-blind 52-week comparison. Am J Psychiatry 2007, 164:1050-1060.
    • (2007) Am J Psychiatry , vol.164 , pp. 1050-1060
    • McEvoy, J.P.1    Lieberman, J.A.2    Perkins, D.O.3    et al4
  • 76
    • 44949155699 scopus 로고    scopus 로고
    • Antipsychotic-induced weight gain in chronic and first-episode psychotic disorders: a systematic critical reappraisal
    • Alvarez-Jimenez M, Gonzalez-Blanch C, Crespo-Facorro B. Antipsychotic-induced weight gain in chronic and first-episode psychotic disorders: a systematic critical reappraisal. CNS Drugs 2008, 22:547-562.
    • (2008) CNS Drugs , vol.22 , pp. 547-562
    • Alvarez-Jimenez, M.1    Gonzalez-Blanch, C.2    Crespo-Facorro, B.3    et al4
  • 77
    • 34447300177 scopus 로고    scopus 로고
    • Weight gain as an adverse effect of some commonly prescribed drugs: a systematic review
    • Leslie WS, Hankey CR, Lean ME. Weight gain as an adverse effect of some commonly prescribed drugs: a systematic review. QJM 2007, 100:395-404.
    • (2007) QJM , vol.100 , pp. 395-404
    • Leslie, W.S.1    Hankey, C.R.2    Lean, M.E.3
  • 78
    • 0032751075 scopus 로고    scopus 로고
    • Antipsychotic-induced weight gain: a comprehensive research synthesis
    • Allison DB, Mentore JL, Heo M. Antipsychotic-induced weight gain: a comprehensive research synthesis. Am J Psychiatry 1999, 156:1686-1696.
    • (1999) Am J Psychiatry , vol.156 , pp. 1686-1696
    • Allison, D.B.1    Mentore, J.L.2    Heo, M.3    et al4
  • 79
    • 33645464191 scopus 로고    scopus 로고
    • Weight change with atypical antipsychotics in the treatment of schizophrenia
    • Haddad P. Weight change with atypical antipsychotics in the treatment of schizophrenia. J Psychopharmacol 2005, 19(6 Suppl):16-27.
    • (2005) J Psychopharmacol , vol.19 , Issue.6 SUPPL , pp. 16-27
    • Haddad, P.1
  • 80
    • 33645700534 scopus 로고    scopus 로고
    • The SOHO (Schizophrenia Outpatient Health Outcome) study: implications for the treatment of schizophrenia
    • Haro JM, Salvador-Carulla L. The SOHO (Schizophrenia Outpatient Health Outcome) study: implications for the treatment of schizophrenia. CNS Drugs 2006, 20:293-301.
    • (2006) CNS Drugs , vol.20 , pp. 293-301
    • Haro, J.M.1    Salvador-Carulla, L.2
  • 81
    • 0347596648 scopus 로고    scopus 로고
    • Obesity as a risk factor for antipsychotic noncompliance
    • Weiden PJ, Mackell JA, McDonnell DD. Obesity as a risk factor for antipsychotic noncompliance. Schizophr Res 2004, 66:51-57.
    • (2004) Schizophr Res , vol.66 , pp. 51-57
    • Weiden, P.J.1    Mackell, J.A.2    McDonnell, D.D.3
  • 82
    • 18844364769 scopus 로고    scopus 로고
    • Association between early and rapid weight gain and change in weight over one year of olanzapine therapy in patients with schizophrenia and related disorders
    • Kinon BJ, Kaiser CJ, Ahmed S, Rotelli MD, Kollack-Walker S. Association between early and rapid weight gain and change in weight over one year of olanzapine therapy in patients with schizophrenia and related disorders. J Clin Psychopharmacol 2005, 25:255-258.
    • (2005) J Clin Psychopharmacol , vol.25 , pp. 255-258
    • Kinon, B.J.1    Kaiser, C.J.2    Ahmed, S.3    Rotelli, M.D.4    Kollack-Walker, S.5
  • 83
    • 25144456112 scopus 로고    scopus 로고
    • Effectiveness of antipsychotic drugs in patients with chronic schizophrenia
    • Lieberman JA, Stroup TS, McEvoy JP. Effectiveness of antipsychotic drugs in patients with chronic schizophrenia. N Engl J Med 2005, 353:1209-1223.
    • (2005) N Engl J Med , vol.353 , pp. 1209-1223
    • Lieberman, J.A.1    Stroup, T.S.2    McEvoy, J.P.3    et al4
  • 84
    • 0030993030 scopus 로고    scopus 로고
    • Olanzapine versus haloperidol in the treatment of schizophrenia and schizoaffective and schizophreniform disorders: results of an international collaborative trial
    • Tollefson GD, Beasley CM, Tran PV. Olanzapine versus haloperidol in the treatment of schizophrenia and schizoaffective and schizophreniform disorders: results of an international collaborative trial. Am J Psychiatry 1997, 154:457-465.
    • (1997) Am J Psychiatry , vol.154 , pp. 457-465
    • Tollefson, G.D.1    Beasley, C.M.2    Tran, P.V.3    et al4
  • 85
    • 0034910756 scopus 로고    scopus 로고
    • Bodyweight gain associated with atypical antipsychotics: epidemiology and therapeutic implications
    • Russell JM, Mackell JA. Bodyweight gain associated with atypical antipsychotics: epidemiology and therapeutic implications. CNS Drugs 2001, 15:537-551.
    • (2001) CNS Drugs , vol.15 , pp. 537-551
    • Russell, J.M.1    Mackell, J.A.2
  • 86
    • 33744485015 scopus 로고    scopus 로고
    • Early predictors of substantial weight gain in bipolar patients treated with olanzapine
    • Lipkovich I, Citrome L, Perlis R. Early predictors of substantial weight gain in bipolar patients treated with olanzapine. J Clin Psychopharmacol 2006, 26:316-320.
    • (2006) J Clin Psychopharmacol , vol.26 , pp. 316-320
    • Lipkovich, I.1    Citrome, L.2    Perlis, R.3    et al4
  • 87
    • 17644416418 scopus 로고    scopus 로고
    • Is cannabis an anti-antipsychotic? The experience in psychiatric intensive care
    • Isaac M, Isaac M, Holloway F. Is cannabis an anti-antipsychotic? The experience in psychiatric intensive care. Hum Psychopharmacol 2005, 20:207-210.
    • (2005) Hum Psychopharmacol , vol.20 , pp. 207-210
    • Isaac, M.1    Isaac, M.2    Holloway, F.3
  • 88
    • 0035024729 scopus 로고    scopus 로고
    • Factors influencing acute weight change in patients with schizophrenia treated with olanzapine, haloperidol, or risperidone
    • Basson BR, Kinon BJ, Taylor CC, Szymanski KA, Gilmore JA, Tollefson GD. Factors influencing acute weight change in patients with schizophrenia treated with olanzapine, haloperidol, or risperidone. J Clin Psychiatry 2001, 62:231-238.
    • (2001) J Clin Psychiatry , vol.62 , pp. 231-238
    • Basson, B.R.1    Kinon, B.J.2    Taylor, C.C.3    Szymanski, K.A.4    Gilmore, J.A.5    Tollefson, G.D.6
  • 89
    • 0036514352 scopus 로고    scopus 로고
    • Weight gain associated with olanzapine and risperidone in adolescent patients: a comparative prospective study
    • Ratzoni G, Gothelf D, Brand-Gothelf A. Weight gain associated with olanzapine and risperidone in adolescent patients: a comparative prospective study. J Am Acad Child Adolesc Psychiatry 2002, 41:337-343.
    • (2002) J Am Acad Child Adolesc Psychiatry , vol.41 , pp. 337-343
    • Ratzoni, G.1    Gothelf, D.2    Brand-Gothelf, A.3    et al4
  • 90
    • 33646683308 scopus 로고    scopus 로고
    • Risperidone-related weight gain: genetic and nongenetic predictors
    • Lane HY, Liu YC, Huang CL. Risperidone-related weight gain: genetic and nongenetic predictors. J Clin Psychopharmacol 2006, 26:128-134.
    • (2006) J Clin Psychopharmacol , vol.26 , pp. 128-134
    • Lane, H.Y.1    Liu, Y.C.2    Huang, C.L.3    et al4
  • 91
    • 0035039480 scopus 로고    scopus 로고
    • Antipsychotic-associated weight gain and clinical outcome parameters
    • Blin O, Micallef J. Antipsychotic-associated weight gain and clinical outcome parameters. J Clin Psychiatry 2001, 62(Suppl. 7):11-21.
    • (2001) J Clin Psychiatry , vol.62 , Issue.SUPPL. 7 , pp. 11-21
    • Blin, O.1    Micallef, J.2
  • 92
    • 14844297025 scopus 로고    scopus 로고
    • Olanzapine vs. other antipsychotics in actual out-patient settings: six months tolerability results from the European Schizophrenia Out-patient Health Outcomes study
    • Lambert M, Haro JM, Novick D. Olanzapine vs. other antipsychotics in actual out-patient settings: six months tolerability results from the European Schizophrenia Out-patient Health Outcomes study. Acta Psychiatr Scand 2005, 111:232-243.
    • (2005) Acta Psychiatr Scand , vol.111 , pp. 232-243
    • Lambert, M.1    Haro, J.M.2    Novick, D.3    et al4
  • 93
    • 0035108241 scopus 로고    scopus 로고
    • Long-term olanzapine treatment: weight change and weight-related health factors in schizophrenia
    • Kinon BJ, Basson BR, Gilmore JA, Tollefson GD. Long-term olanzapine treatment: weight change and weight-related health factors in schizophrenia. J Clin Psychiatry 2001, 62:92-100.
    • (2001) J Clin Psychiatry , vol.62 , pp. 92-100
    • Kinon, B.J.1    Basson, B.R.2    Gilmore, J.A.3    Tollefson, G.D.4
  • 94
    • 0035124876 scopus 로고    scopus 로고
    • Weight change and atypical antipsychotic treatment in patients with schizophrenia
    • Jones B, Basson BR, Walker DJ, Crawford AM, Kinon BJ. Weight change and atypical antipsychotic treatment in patients with schizophrenia. J Clin Psychiatry 2001, 62(Suppl. 2):41-44.
    • (2001) J Clin Psychiatry , vol.62 , Issue.SUPPL. 2 , pp. 41-44
    • Jones, B.1    Basson, B.R.2    Walker, D.J.3    Crawford, A.M.4    Kinon, B.J.5
  • 95
    • 0035971518 scopus 로고    scopus 로고
    • Weight gain over 4 months in schizophrenia patients: a comparison of olanzapine and risperidone
    • Ganguli R, Brar JS, Ayrton Z. Weight gain over 4 months in schizophrenia patients: a comparison of olanzapine and risperidone. Schizophr Res 2001, 49:261-267.
    • (2001) Schizophr Res , vol.49 , pp. 261-267
    • Ganguli, R.1    Brar, J.S.2    Ayrton, Z.3
  • 96
    • 35748955227 scopus 로고    scopus 로고
    • Olanzapine versus placebo in the treatment of adolescents with bipolar mania
    • Tohen M, Kryzhanovskaya L, Carlson G. Olanzapine versus placebo in the treatment of adolescents with bipolar mania. Am J Psychiatry 2007, 164:1547-1556.
    • (2007) Am J Psychiatry , vol.164 , pp. 1547-1556
    • Tohen, M.1    Kryzhanovskaya, L.2    Carlson, G.3    et al4
  • 97
    • 0034786122 scopus 로고    scopus 로고
    • A prospective open-label treatment trial of olanzapine monotherapy in children and adolescents with bipolar disorder
    • Frazier JA, Biederman J, Tohen M. A prospective open-label treatment trial of olanzapine monotherapy in children and adolescents with bipolar disorder. J Child Adolesc Psychopharmacol 2001, 11:239-250.
    • (2001) J Child Adolesc Psychopharmacol , vol.11 , pp. 239-250
    • Frazier, J.A.1    Biederman, J.2    Tohen, M.3    et al4
  • 98
    • 35948994989 scopus 로고    scopus 로고
    • Aripiprazole in juvenile bipolar disorder comorbid with attention-deficit/hyperactivity disorder: an open clinical trial
    • Tramontina S, Zeni CP, Pheula GF, de Souza CK, Rohde LA. Aripiprazole in juvenile bipolar disorder comorbid with attention-deficit/hyperactivity disorder: an open clinical trial. CNS Spectr 2007, 12:758-762.
    • (2007) CNS Spectr , vol.12 , pp. 758-762
    • Tramontina, S.1    Zeni, C.P.2    Pheula, G.F.3    de Souza, C.K.4    Rohde, L.A.5
  • 99
    • 34248519860 scopus 로고    scopus 로고
    • Expert Consensus Meeting, Dublin, 14-15 April 2005, consensus summary. Metabolic and lifestyle issues and severe mental illness - new connections to well-being
    • Expert Consensus Meeting, Dublin, 14-15 April 2005, consensus summary. Metabolic and lifestyle issues and severe mental illness - new connections to well-being. J Psychopharmacol 2005, 19(Suppl):118-122.
    • (2005) J Psychopharmacol , vol.19 , Issue.SUPPL , pp. 118-122
  • 100
    • 0346908838 scopus 로고    scopus 로고
    • London, Published by the, National Institute for Clinical Excellence, Available from URL, (Accessed 12 February 2008)
    • Clinical guidelines 1 2002, http://www.nice.org.uk, London, Published by the, National Institute for Clinical Excellence, Available from URL, (Accessed 12 February 2008)
    • (2002) Clinical guidelines 1
  • 101
    • 0842348094 scopus 로고    scopus 로고
    • Consensus development conference on antipsychotic drugs and obesity and diabetes
    • Consensus development conference on antipsychotic drugs and obesity and diabetes. Diabetes Care 2004, 27:596-601.
    • (2004) Diabetes Care , vol.27 , pp. 596-601
  • 102
    • 33748998982 scopus 로고    scopus 로고
    • Genetics of antipsychotic treatment emergent weight gain in schizophrenia
    • Muller DJ, Kennedy JL. Genetics of antipsychotic treatment emergent weight gain in schizophrenia. Pharmacogenomics 2006, 7:863-887.
    • (2006) Pharmacogenomics , vol.7 , pp. 863-887
    • Muller, D.J.1    Kennedy, J.L.2
  • 103
    • 0037097014 scopus 로고    scopus 로고
    • Association of antipsychotic drug-induced weight gain with a 5-HT2C receptor gene polymorphism
    • Reynolds GP, Zhang ZJ, Zhang XB. Association of antipsychotic drug-induced weight gain with a 5-HT2C receptor gene polymorphism. Lancet 2002, 359:2086-2087.
    • (2002) Lancet , vol.359 , pp. 2086-2087
    • Reynolds, G.P.1    Zhang, Z.J.2    Zhang, X.B.3
  • 104
    • 0038474172 scopus 로고    scopus 로고
    • Polymorphism of the promoter region of the serotonin 5-HT(2C) receptor gene and clozapine-induced weight gain
    • Reynolds GP, Zhang Z, Zhang X. Polymorphism of the promoter region of the serotonin 5-HT(2C) receptor gene and clozapine-induced weight gain. Am J Psychiatry 2003, 160:677-679.
    • (2003) Am J Psychiatry , vol.160 , pp. 677-679
    • Reynolds, G.P.1    Zhang, Z.2    Zhang, X.3
  • 105
    • 23144441853 scopus 로고    scopus 로고
    • The role of 5-HT2C receptor polymorphisms in the pharmacogenetics of antipsychotic drug treatment
    • Reynolds GP, Templeman LA, Zhang ZJ. The role of 5-HT2C receptor polymorphisms in the pharmacogenetics of antipsychotic drug treatment. Prog Neuropsychopharmacol Biol Psychiatry 2005, 29:1021-1028.
    • (2005) Prog Neuropsychopharmacol Biol Psychiatry , vol.29 , pp. 1021-1028
    • Reynolds, G.P.1    Templeman, L.A.2    Zhang, Z.J.3
  • 106
    • 17644394540 scopus 로고    scopus 로고
    • Polymorphisms of the 5-HT2C receptor and leptin genes are associated with antipsychotic drug-induced weight gain in Caucasian subjects with a first-episode psychosis
    • Templeman LA, Reynolds GP, Arranz B, San L. Polymorphisms of the 5-HT2C receptor and leptin genes are associated with antipsychotic drug-induced weight gain in Caucasian subjects with a first-episode psychosis. Pharmacogenet Genomics 2005, 15:195-200.
    • (2005) Pharmacogenet Genomics , vol.15 , pp. 195-200
    • Templeman, L.A.1    Reynolds, G.P.2    Arranz, B.3    San, L.4
  • 107
    • 0037202751 scopus 로고    scopus 로고
    • 759C/T genetic variation of 5HT(2C) receptor and clozapine-induced weight gain
    • Basile VS, Masellis M, De Luca V, Meltzer HY, Kennedy JL. 759C/T genetic variation of 5HT(2C) receptor and clozapine-induced weight gain. Lancet 2002, 30:1790-1791.
    • (2002) Lancet , vol.30 , pp. 1790-1791
    • Basile, V.S.1    Masellis, M.2    De Luca, V.3    Meltzer, H.Y.4    Kennedy, J.L.5
  • 109
    • 0036894725 scopus 로고    scopus 로고
    • 5HT2A and 5HT2C receptor polymorphisms and predicting clinical response to olanzapine in schizophrenia
    • Ellingrod VL, Perry PJ, Lund BC. 5HT2A and 5HT2C receptor polymorphisms and predicting clinical response to olanzapine in schizophrenia. J Clin Psychopharmacol 2002, 22:622-624.
    • (2002) J Clin Psychopharmacol , vol.22 , pp. 622-624
    • Ellingrod, V.L.1    Perry, P.J.2    Lund, B.C.3    et al4
  • 110
    • 2342525335 scopus 로고    scopus 로고
    • [Association of -2548G/A functional polymorphism in the promoter region of leptin gene with antipsychotic agent-induced weight gain]
    • Zhang ZJ, Yao ZJ, Mou XD. [Association of -2548G/A functional polymorphism in the promoter region of leptin gene with antipsychotic agent-induced weight gain]. Zhonghua Yi Xue Za Zhi 2003, 83:2119-2123.
    • (2003) Zhonghua Yi Xue Za Zhi , vol.83 , pp. 2119-2123
    • Zhang, Z.J.1    Yao, Z.J.2    Mou, X.D.3    et al4
  • 111
    • 34247890009 scopus 로고    scopus 로고
    • Leptin and leptin receptor gene polymorphisms and increases in body mass index (BMI) from olanzapine treatment in persons with schizophrenia
    • Ellingrod VL, Bishop JR, Moline J, Lin YC, Miller dD. Leptin and leptin receptor gene polymorphisms and increases in body mass index (BMI) from olanzapine treatment in persons with schizophrenia. Psychopharmacol Bull 2007, 40:57-62.
    • (2007) Psychopharmacol Bull , vol.40 , pp. 57-62
    • Ellingrod, V.L.1    Bishop, J.R.2    Moline, J.3    Lin, Y.C.4    Miller, D.5
  • 112
    • 38349056887 scopus 로고    scopus 로고
    • Possible association between the -2548A/G polymorphism of the leptin gene and olanzapine-induced weight gain
    • Kang SG, Lee HJ, Park YM. Possible association between the -2548A/G polymorphism of the leptin gene and olanzapine-induced weight gain. Prog Neuropsychopharmacol Biol Psychiatry 2008, 32:160-163.
    • (2008) Prog Neuropsychopharmacol Biol Psychiatry , vol.32 , pp. 160-163
    • Kang, S.G.1    Lee, H.J.2    Park, Y.M.3    et al4
  • 113
    • 33947512695 scopus 로고    scopus 로고
    • 759 C/T polymorphism of 5-HT2C receptor gene and early phase weight gain associated with antipsychotic drug treatment
    • Ryu S, Cho EY, Park T. 759 C/T polymorphism of 5-HT2C receptor gene and early phase weight gain associated with antipsychotic drug treatment. Prog Neuropsychopharmacol Biol Psychiatry 2007, 31:673-677.
    • (2007) Prog Neuropsychopharmacol Biol Psychiatry , vol.31 , pp. 673-677
    • Ryu, S.1    Cho, E.Y.2    Park, T.3    et al4
  • 114
    • 25144477595 scopus 로고    scopus 로고
    • Polymorphism of the adrenergic receptor alpha 2a -1291C>G genetic variation and clozapine-induced weight gain
    • Wang YC, Bai YM, Chen JY, Lin CC, Lai IC, Liou YJ. Polymorphism of the adrenergic receptor alpha 2a -1291C>G genetic variation and clozapine-induced weight gain. J Neural Transm 2005, 112:1463-1468.
    • (2005) J Neural Transm , vol.112 , pp. 1463-1468
    • Wang, Y.C.1    Bai, Y.M.2    Chen, J.Y.3    Lin, C.C.4    Lai, I.C.5    Liou, Y.J.6
  • 115
    • 25144497419 scopus 로고    scopus 로고
    • C825T polymorphism in the human G protein beta3 subunit gene is associated with long-term clozapine treatment-induced body weight change in the Chinese population
    • Wang YC, Bai YM, Chen JY, Lin CC, Lai IC, Liou YJ. C825T polymorphism in the human G protein beta3 subunit gene is associated with long-term clozapine treatment-induced body weight change in the Chinese population. Pharmacogenet Genomics 2005, 15:743-748.
    • (2005) Pharmacogenet Genomics , vol.15 , pp. 743-748
    • Wang, Y.C.1    Bai, Y.M.2    Chen, J.Y.3    Lin, C.C.4    Lai, I.C.5    Liou, Y.J.6
  • 116
    • 20144388485 scopus 로고    scopus 로고
    • The SNAP-25 gene may be associated with clinical response and weight gain in antipsychotic treatment of schizophrenia
    • Muller DJ, Klempan TA, De Luca V. The SNAP-25 gene may be associated with clinical response and weight gain in antipsychotic treatment of schizophrenia. Neurosci Lett 2005, 379:81-89.
    • (2005) Neurosci Lett , vol.379 , pp. 81-89
    • Muller, D.J.1    Klempan, T.A.2    De Luca, V.3    et al4
  • 117
    • 49149108655 scopus 로고    scopus 로고
    • SNAP-25 gene polymorphisms and weight gain in schizophrenic patients
    • Musil R, Spellmann I, Riedel M. SNAP-25 gene polymorphisms and weight gain in schizophrenic patients. J Psychiatr Res 2008, 42:963-970.
    • (2008) J Psychiatr Res , vol.42 , pp. 963-970
    • Musil, R.1    Spellmann, I.2    Riedel, M.3    et al4
  • 118
    • 47249138191 scopus 로고    scopus 로고
    • BDNF levels and genotype are associated with antipsychotic-induced weight gain in patients with chronic schizophrenia
    • Zhang XY, Zhou DF, Wu GY. BDNF levels and genotype are associated with antipsychotic-induced weight gain in patients with chronic schizophrenia. Neuropsychopharmacology 2008, 33:2200-2205.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 2200-2205
    • Zhang, X.Y.1    Zhou, D.F.2    Wu, G.Y.3    et al4
  • 120
    • 45849139351 scopus 로고    scopus 로고
    • Antipsychotic induced weight gain in schizophrenia: mechanisms and management
    • Rege S. Antipsychotic induced weight gain in schizophrenia: mechanisms and management. Aust N Z J Psychiatry 2008, 42:369-381.
    • (2008) Aust N Z J Psychiatry , vol.42 , pp. 369-381
    • Rege, S.1
  • 121
    • 39649118908 scopus 로고    scopus 로고
    • Clozapine and olanzapine are associated with food craving and binge eating: results from a randomized double-blind study
    • Kluge M, Schuld A, Himmerich H. Clozapine and olanzapine are associated with food craving and binge eating: results from a randomized double-blind study. J Clin Psychopharmacol 2007, 27:662-666.
    • (2007) J Clin Psychopharmacol , vol.27 , pp. 662-666
    • Kluge, M.1    Schuld, A.2    Himmerich, H.3    et al4
  • 122
    • 34547124048 scopus 로고    scopus 로고
    • Clozapine/olanzapine-induced recurrence or deterioration of binge eating-related eating disorders
    • Gebhardt S, Haberhausen M, Krieg JC. Clozapine/olanzapine-induced recurrence or deterioration of binge eating-related eating disorders. J Neural Transm 2007, 114:1091-1095.
    • (2007) J Neural Transm , vol.114 , pp. 1091-1095
    • Gebhardt, S.1    Haberhausen, M.2    Krieg, J.C.3    et al4
  • 123
    • 33646249125 scopus 로고    scopus 로고
    • The hypothalamic H1 receptor: a novel therapeutic target for disrupting diurnal feeding rhythm and obesity
    • Masaki T, Yoshimatsu H. The hypothalamic H1 receptor: a novel therapeutic target for disrupting diurnal feeding rhythm and obesity. Trends Pharmacol Sci 2006, 27:279-284.
    • (2006) Trends Pharmacol Sci , vol.27 , pp. 279-284
    • Masaki, T.1    Yoshimatsu, H.2
  • 124
    • 0035140171 scopus 로고    scopus 로고
    • Central infusion of histamine reduces fat accumulation and upregulates UCP family in leptin-resistant obese mice
    • Masaki T, Yoshimatsu H, Chiba S, Watanabe T, Sakata T. Central infusion of histamine reduces fat accumulation and upregulates UCP family in leptin-resistant obese mice. Diabetes 2001, 50:376-384.
    • (2001) Diabetes , vol.50 , pp. 376-384
    • Masaki, T.1    Yoshimatsu, H.2    Chiba, S.3    Watanabe, T.4    Sakata, T.5
  • 125
    • 0035140173 scopus 로고    scopus 로고
    • Targeted disruption of histamine H1-receptor attenuates regulatory effects of leptin on feeding, adiposity, and UCP family in mice
    • Masaki T, Yoshimatsu H, Chiba S, Watanabe T, Sakata T. Targeted disruption of histamine H1-receptor attenuates regulatory effects of leptin on feeding, adiposity, and UCP family in mice. Diabetes 2001, 50:385-391.
    • (2001) Diabetes , vol.50 , pp. 385-391
    • Masaki, T.1    Yoshimatsu, H.2    Chiba, S.3    Watanabe, T.4    Sakata, T.5
  • 126
    • 0034711425 scopus 로고    scopus 로고
    • Binding of antipsychotic drugs to human brain receptors focus on newer generation compounds
    • Richelson E, Souder T. Binding of antipsychotic drugs to human brain receptors focus on newer generation compounds. Life Sci 2000, 68:29-39.
    • (2000) Life Sci , vol.68 , pp. 29-39
    • Richelson, E.1    Souder, T.2
  • 127
    • 37249034101 scopus 로고    scopus 로고
    • Atypical antipsychotic-induced metabolic side effects: insights from receptor-binding profiles
    • Nasrallah HA. Atypical antipsychotic-induced metabolic side effects: insights from receptor-binding profiles. Mol Psychiatry 2008, 13:27-35.
    • (2008) Mol Psychiatry , vol.13 , pp. 27-35
    • Nasrallah, H.A.1
  • 128
  • 129
    • 33847635179 scopus 로고    scopus 로고
    • From the cover: antipsychotic drug-induced weight gain mediated by histamine H1 receptor-linked activation of hypothalamic AMP-kinase
    • Kim SF, Huang AS, Snowman AM, Teuscher C, Snyder SH. From the cover: antipsychotic drug-induced weight gain mediated by histamine H1 receptor-linked activation of hypothalamic AMP-kinase. Proc Natl Acad Sci U S A 2007, 104:3456-3459.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 3456-3459
    • Kim, S.F.1    Huang, A.S.2    Snowman, A.M.3    Teuscher, C.4    Snyder, S.H.5
  • 130
    • 33644684681 scopus 로고    scopus 로고
    • Receptor occupancy-based analysis of the contributions of various receptors to antipsychotics-induced weight gain and diabetes mellitus
    • Matsui-Sakata A, Ohtani H, Sawada Y. Receptor occupancy-based analysis of the contributions of various receptors to antipsychotics-induced weight gain and diabetes mellitus. Drug Metab Pharmacokinet 2005, 20:368-378.
    • (2005) Drug Metab Pharmacokinet , vol.20 , pp. 368-378
    • Matsui-Sakata, A.1    Ohtani, H.2    Sawada, Y.3
  • 131
    • 10744226540 scopus 로고    scopus 로고
    • H(1)-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs
    • Goudie AJ, Halford JC, Dovey TM, Cooper GD, Neill JC. H(1)-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs. Neuropsychopharmacology 2003, 28:2209-2211.
    • (2003) Neuropsychopharmacology , vol.28 , pp. 2209-2211
    • Goudie, A.J.1    Halford, J.C.2    Dovey, T.M.3    Cooper, G.D.4    Neill, J.C.5
  • 132
    • 0038014053 scopus 로고    scopus 로고
    • H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs
    • Kroeze WK, Hufeisen SJ, Popadak BA. H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs. Neuropsychopharmacology 2003, 28:519-526.
    • (2003) Neuropsychopharmacology , vol.28 , pp. 519-526
    • Kroeze, W.K.1    Hufeisen, S.J.2    Popadak, B.A.3    et al4
  • 133
    • 14844355232 scopus 로고    scopus 로고
    • The effect of betahistine, a histamine H1 receptor agonist/H3 antagonist, on olanzapine-induced weight gain in first-episode schizophrenia patients
    • Poyurovsky M, Pashinian A, Levi A, Weizman R, Weizman A. The effect of betahistine, a histamine H1 receptor agonist/H3 antagonist, on olanzapine-induced weight gain in first-episode schizophrenia patients. Int Clin Psychopharmacol 2005, 20:101-103.
    • (2005) Int Clin Psychopharmacol , vol.20 , pp. 101-103
    • Poyurovsky, M.1    Pashinian, A.2    Levi, A.3    Weizman, R.4    Weizman, A.5
  • 134
    • 0029985448 scopus 로고    scopus 로고
    • The serotonergic agent fluoxetine reduces neuropeptide Y levels and neuropeptide Y secretion in the hypothalamus of lean and obese rats
    • Dryden S, Frankish HM, Wang Q, Pickavance L, Williams G. The serotonergic agent fluoxetine reduces neuropeptide Y levels and neuropeptide Y secretion in the hypothalamus of lean and obese rats. Neuroscience 1996, 72:557-566.
    • (1996) Neuroscience , vol.72 , pp. 557-566
    • Dryden, S.1    Frankish, H.M.2    Wang, Q.3    Pickavance, L.4    Williams, G.5
  • 135
    • 0028909857 scopus 로고
    • Eating disorder and epilepsy in mice lacking 5-HT2c serotonin receptors
    • Tecott LH, Sun LM, Akana SF. Eating disorder and epilepsy in mice lacking 5-HT2c serotonin receptors. Nature 1995, 374:542-546.
    • (1995) Nature , vol.374 , pp. 542-546
    • Tecott, L.H.1    Sun, L.M.2    Akana, S.F.3    et al4
  • 136
    • 33745427099 scopus 로고    scopus 로고
    • Olanzapine differentially affects 5-HT2Aand2C receptor mRNA expression in the rat brain
    • Huang XF, Han M, Huang X, Zavitsanou K, Deng C. Olanzapine differentially affects 5-HT2Aand2C receptor mRNA expression in the rat brain. Behav Brain Res 2006, 171:355-362.
    • (2006) Behav Brain Res , vol.171 , pp. 355-362
    • Huang, X.F.1    Han, M.2    Huang, X.3    Zavitsanou, K.4    Deng, C.5
  • 137
    • 33745025286 scopus 로고    scopus 로고
    • Clozapine, but not haloperidol, increases neuropeptide Y neuronal expression in the rat hypothalamus
    • Kirk SL, Cahir M, Reynolds GP. Clozapine, but not haloperidol, increases neuropeptide Y neuronal expression in the rat hypothalamus. J Psychopharmacol 2006, 20:577-579.
    • (2006) J Psychopharmacol , vol.20 , pp. 577-579
    • Kirk, S.L.1    Cahir, M.2    Reynolds, G.P.3
  • 138
    • 0031770263 scopus 로고    scopus 로고
    • Influence of typical and atypical antipsychotics on neuropeptide Y-like immunoreactivity and NPY mRNA expression in rat striatum
    • Obuchowicz E, Turchan J. Influence of typical and atypical antipsychotics on neuropeptide Y-like immunoreactivity and NPY mRNA expression in rat striatum. Neuropeptides 1998, 32:473-480.
    • (1998) Neuropeptides , vol.32 , pp. 473-480
    • Obuchowicz, E.1    Turchan, J.2
  • 139
    • 33646428953 scopus 로고    scopus 로고
    • Neuropeptide Y mRNA expression levels following chronic olanzapine, clozapine and haloperidol administration in rats
    • Huang XF, Deng C, Zavitsanou K. Neuropeptide Y mRNA expression levels following chronic olanzapine, clozapine and haloperidol administration in rats. Neuropeptides 2006, 40:213-219.
    • (2006) Neuropeptides , vol.40 , pp. 213-219
    • Huang, X.F.1    Deng, C.2    Zavitsanou, K.3
  • 140
    • 0036703780 scopus 로고    scopus 로고
    • Differential activation of orexin neurons by antipsychotic drugs associated with weight gain
    • Fadel J, Bubser M, Deutch AY. Differential activation of orexin neurons by antipsychotic drugs associated with weight gain. J Neurosci 2002, 22:6742-6746.
    • (2002) J Neurosci , vol.22 , pp. 6742-6746
    • Fadel, J.1    Bubser, M.2    Deutch, A.Y.3
  • 141
    • 16844363642 scopus 로고    scopus 로고
    • Effect of chronic olanzapine treatment on nerve growth factor and brain-derived neurotrophic factor in the rat brain
    • Angelucci F, Aloe L, Iannitelli A, Gruber SH, Mathe AA. Effect of chronic olanzapine treatment on nerve growth factor and brain-derived neurotrophic factor in the rat brain. Eur Neuropsychopharmacol 2005, 15:311-317.
    • (2005) Eur Neuropsychopharmacol , vol.15 , pp. 311-317
    • Angelucci, F.1    Aloe, L.2    Iannitelli, A.3    Gruber, S.H.4    Mathe, A.A.5
  • 142
    • 0242351929 scopus 로고    scopus 로고
    • Lower CSF orexin A (hypocretin-1) levels in patients with schizophrenia treated with haloperidol compared to unmedicated subjects
    • Dalal MA, Schuld A, Pollmacher T. Lower CSF orexin A (hypocretin-1) levels in patients with schizophrenia treated with haloperidol compared to unmedicated subjects. Mol Psychiatry 2003, 8:836-837.
    • (2003) Mol Psychiatry , vol.8 , pp. 836-837
    • Dalal, M.A.1    Schuld, A.2    Pollmacher, T.3
  • 143
    • 0036276522 scopus 로고    scopus 로고
    • Weight gain associated with increased food intake and low habitual activity levels in male adolescent schizophrenic inpatients treated with olanzapine
    • Gothelf D, Falk B, Singer P. Weight gain associated with increased food intake and low habitual activity levels in male adolescent schizophrenic inpatients treated with olanzapine. Am J Psychiatry 2002, 159:1055-1057.
    • (2002) Am J Psychiatry , vol.159 , pp. 1055-1057
    • Gothelf, D.1    Falk, B.2    Singer, P.3    et al4
  • 144
    • 32844467665 scopus 로고    scopus 로고
    • Olanzapine impairs glycogen synthesis and insulin signaling in L6 skeletal muscle cells
    • Engl J, Laimer M, Niederwanger A. Olanzapine impairs glycogen synthesis and insulin signaling in L6 skeletal muscle cells. Mol Psychiatry 2005, 10:1089-1096.
    • (2005) Mol Psychiatry , vol.10 , pp. 1089-1096
    • Engl, J.1    Laimer, M.2    Niederwanger, A.3    et al4
  • 145
    • 14644415476 scopus 로고    scopus 로고
    • Metabolic dysregulation with atypical antipsychotics occurs in the absence of underlying disease: a placebo-controlled study of olanzapine and risperidone in dogs
    • Ader M, Kim SP, Catalano KJ. Metabolic dysregulation with atypical antipsychotics occurs in the absence of underlying disease: a placebo-controlled study of olanzapine and risperidone in dogs. Diabetes 2005, 54:862-871.
    • (2005) Diabetes , vol.54 , pp. 862-871
    • Ader, M.1    Kim, S.P.2    Catalano, K.J.3    et al4
  • 146
    • 33745905593 scopus 로고    scopus 로고
    • Cannabis and neurodevelopment: implications for psychiatric disorders
    • Sundram S. Cannabis and neurodevelopment: implications for psychiatric disorders. Hum Psychopharmacol 2006, 21:245-254.
    • (2006) Hum Psychopharmacol , vol.21 , pp. 245-254
    • Sundram, S.1
  • 147
    • 33751169802 scopus 로고    scopus 로고
    • Long-term safety and tolerability of long-acting injectable risperidone in patients with schizophrenia or schizoaffective disorder
    • Lindenmayer JP, Khan A, Eerdekens M, Van Hove I, Kushner S. Long-term safety and tolerability of long-acting injectable risperidone in patients with schizophrenia or schizoaffective disorder. Eur Neuropsychopharmacol 2007, 17:138-144.
    • (2007) Eur Neuropsychopharmacol , vol.17 , pp. 138-144
    • Lindenmayer, J.P.1    Khan, A.2    Eerdekens, M.3    Van Hove, I.4    Kushner, S.5
  • 148
    • 0038149626 scopus 로고    scopus 로고
    • Long-acting injectable risperidone: efficacy and safety of the first long-acting atypical antipsychotic
    • Kane JM, Eerdekens M, Lindenmayer JP, Keith SJ, Lesem M, Karcher K. Long-acting injectable risperidone: efficacy and safety of the first long-acting atypical antipsychotic. Am J Psychiatry 2003, 160:1125-1132.
    • (2003) Am J Psychiatry , vol.160 , pp. 1125-1132
    • Kane, J.M.1    Eerdekens, M.2    Lindenmayer, J.P.3    Keith, S.J.4    Lesem, M.5    Karcher, K.6
  • 149
    • 42549153837 scopus 로고    scopus 로고
    • Long-term weight loss observed with olanzapine orally disintegrating tablets in overweight patients with chronic schizophrenia. A 1 year open-label, prospective trial
    • Chawla B, Luxton-Andrew H. Long-term weight loss observed with olanzapine orally disintegrating tablets in overweight patients with chronic schizophrenia. A 1 year open-label, prospective trial. Hum Psychopharmacol 2008, 23:211-216.
    • (2008) Hum Psychopharmacol , vol.23 , pp. 211-216
    • Chawla, B.1    Luxton-Andrew, H.2
  • 150
    • 35348992825 scopus 로고    scopus 로고
    • Orally disintegrating olanzapine induces less weight gain in adolescents than standard oral tablets
    • Crocq MA, Guillon MS, Bailey PE, Provost D. Orally disintegrating olanzapine induces less weight gain in adolescents than standard oral tablets. Eur Psychiatry 2007, 22:453-454.
    • (2007) Eur Psychiatry , vol.22 , pp. 453-454
    • Crocq, M.A.1    Guillon, M.S.2    Bailey, P.E.3    Provost, D.4
  • 151
    • 33846596713 scopus 로고    scopus 로고
    • Lower weight gain with the orally disintegrating olanzapine than with standard tablets in first-episode never treated psychotic patients
    • Arranz B, San L, Duenas RM. Lower weight gain with the orally disintegrating olanzapine than with standard tablets in first-episode never treated psychotic patients. Hum Psychopharmacol 2007, 22:11-15.
    • (2007) Hum Psychopharmacol , vol.22 , pp. 11-15
    • Arranz, B.1    San, L.2    Duenas, R.M.3    et al4
  • 153
    • 5444233534 scopus 로고    scopus 로고
    • Weight loss after switching from conventional olanzapine tablets to orally disintegrating olanzapine tablets
    • de Haan L, van Amelsvoort T, Rosien K, Linszen D. Weight loss after switching from conventional olanzapine tablets to orally disintegrating olanzapine tablets. Psychopharmacology 2004, 175:389-390.
    • (2004) Psychopharmacology , vol.175 , pp. 389-390
    • de Haan, L.1    van Amelsvoort, T.2    Rosien, K.3    Linszen, D.4
  • 154
    • 34547524961 scopus 로고    scopus 로고
    • Do formulation switches exacerbate existing medical illness? Results of an open-label transition to orally disintegrating risperidone tablets
    • Chue P, Prinzo RS, Binder CE. Do formulation switches exacerbate existing medical illness? Results of an open-label transition to orally disintegrating risperidone tablets. Hum Psychopharmacol 2007, 22:307-314.
    • (2007) Hum Psychopharmacol , vol.22 , pp. 307-314
    • Chue, P.1    Prinzo, R.S.2    Binder, C.E.3
  • 155
    • 12144288597 scopus 로고    scopus 로고
    • Serum ghrelin concentrations in patients receiving olanzapine or risperidone
    • Togo T, Hasegawa K, Miura S. Serum ghrelin concentrations in patients receiving olanzapine or risperidone. Psychopharmacology 2004, 172:230-232.
    • (2004) Psychopharmacology , vol.172 , pp. 230-232
    • Togo, T.1    Hasegawa, K.2    Miura, S.3    et al4
  • 156
    • 20444379998 scopus 로고    scopus 로고
    • Correlation of serum ghrelin levels with body mass index and carbohydrate metabolism in patients treated with atypical antipsychotics
    • Palik E, Birkas KD, Faludi G, Karadi I, Cseh K. Correlation of serum ghrelin levels with body mass index and carbohydrate metabolism in patients treated with atypical antipsychotics. Diabetes Res Clin Pract 2005, 68(Suppl. 1):S60-S64.
    • (2005) Diabetes Res Clin Pract , vol.68 , Issue.SUPPL. 1
    • Palik, E.1    Birkas, K.D.2    Faludi, G.3    Karadi, I.4    Cseh, K.5
  • 157
    • 23944508874 scopus 로고    scopus 로고
    • Hormonal correlates of clozapine-induced weight gain in psychotic children: an exploratory study
    • Sporn AL, Bobb AJ, Gogtay N. Hormonal correlates of clozapine-induced weight gain in psychotic children: an exploratory study. J Am Acad Child Adolesc Psychiatry 2005, 44:925-933.
    • (2005) J Am Acad Child Adolesc Psychiatry , vol.44 , pp. 925-933
    • Sporn, A.L.1    Bobb, A.J.2    Gogtay, N.3    et al4
  • 158
    • 25144504301 scopus 로고    scopus 로고
    • A prospective study of serum ghrelin levels in patients treated with clozapine
    • Theisen FM, Gebhardt S, Bromel T. A prospective study of serum ghrelin levels in patients treated with clozapine. J Neural Transm 2005, 112:1411-1416.
    • (2005) J Neural Transm , vol.112 , pp. 1411-1416
    • Theisen, F.M.1    Gebhardt, S.2    Bromel, T.3    et al4
  • 159
    • 21344462380 scopus 로고    scopus 로고
    • Ghrelin plasma levels during psychopharmacological treatment
    • Himmerich H, Fulda S, Kunzel HE. Ghrelin plasma levels during psychopharmacological treatment. Neuropsychobiology 2005, 52:11-16.
    • (2005) Neuropsychobiology , vol.52 , pp. 11-16
    • Himmerich, H.1    Fulda, S.2    Kunzel, H.E.3    et al4
  • 160
    • 34547150496 scopus 로고    scopus 로고
    • Changes in neuroendocrine and metabolic hormones induced by atypical antipsychotics in normal-weight patients with schizophrenia
    • Popovic V, Doknic M, Maric N. Changes in neuroendocrine and metabolic hormones induced by atypical antipsychotics in normal-weight patients with schizophrenia. Neuroendocrinology 2007, 85:249-256.
    • (2007) Neuroendocrinology , vol.85 , pp. 249-256
    • Popovic, V.1    Doknic, M.2    Maric, N.3    et al4
  • 161
    • 0033759310 scopus 로고    scopus 로고
    • Elevated levels of insulin, leptin, and blood lipids in olanzapine-treated patients with schizophrenia or related psychoses
    • Melkersson KI, Hulting AL, Brismar KE. Elevated levels of insulin, leptin, and blood lipids in olanzapine-treated patients with schizophrenia or related psychoses. J Clin Psychiatry 2000, 61:742-749.
    • (2000) J Clin Psychiatry , vol.61 , pp. 742-749
    • Melkersson, K.I.1    Hulting, A.L.2    Brismar, K.E.3
  • 162
    • 0035111503 scopus 로고    scopus 로고
    • Insulin and leptin levels in patients with schizophrenia or related psychoses - a comparison between different antipsychotic agents
    • Melkersson KI, Hulting AL. Insulin and leptin levels in patients with schizophrenia or related psychoses - a comparison between different antipsychotic agents. Psychopharmacology 2001, 154:205-212.
    • (2001) Psychopharmacology , vol.154 , pp. 205-212
    • Melkersson, K.I.1    Hulting, A.L.2
  • 163
    • 0034809696 scopus 로고    scopus 로고
    • Association of olanzapine-induced weight gain with an increase in body fat
    • Eder U, Mangweth B, Ebenbichler C. Association of olanzapine-induced weight gain with an increase in body fat. Am J Psychiatry 2001, 158:1719-1722.
    • (2001) Am J Psychiatry , vol.158 , pp. 1719-1722
    • Eder, U.1    Mangweth, B.2    Ebenbichler, C.3    et al4
  • 166
    • 34249032097 scopus 로고    scopus 로고
    • Similar frequency of abnormal correlation between serum leptin levels and BMI before and after olanzapine treatment in schizophrenia
    • Baptista T, Davila A, El FY. Similar frequency of abnormal correlation between serum leptin levels and BMI before and after olanzapine treatment in schizophrenia. Int Clin Psychopharmacol 2007, 22:205-211.
    • (2007) Int Clin Psychopharmacol , vol.22 , pp. 205-211
    • Baptista, T.1    Davila, A.2    El, F.Y.3    et al4
  • 167
    • 33745362873 scopus 로고    scopus 로고
    • The efficacy of mifepristone in the reduction and prevention of olanzapine-induced weight gain in rats
    • Beebe KL, Block T, Debattista C, Blasey C, Belanoff JK. The efficacy of mifepristone in the reduction and prevention of olanzapine-induced weight gain in rats. Behav Brain Res 2006, 171:225-229.
    • (2006) Behav Brain Res , vol.171 , pp. 225-229
    • Beebe, K.L.1    Block, T.2    Debattista, C.3    Blasey, C.4    Belanoff, J.K.5
  • 168
    • 33747414468 scopus 로고    scopus 로고
    • Clozapine reverses increased brown adipose tissue thermogenesis induced by 3,4-methylene-dioxymethamphetamine and by cold exposure in conscious rats
    • Blessing WW, Zilm A, Ootsuka Y. Clozapine reverses increased brown adipose tissue thermogenesis induced by 3,4-methylene-dioxymethamphetamine and by cold exposure in conscious rats. Neuroscience 2006, 141:2067-2073.
    • (2006) Neuroscience , vol.141 , pp. 2067-2073
    • Blessing, W.W.1    Zilm, A.2    Ootsuka, Y.3
  • 169
    • 33744992710 scopus 로고    scopus 로고
    • Long term treatment with olanzapine mixed with the food in male rats induces body fat deposition with no increase in body weight and no thermogenic alteration
    • Minet-Ringuet J, Even PC, Goubern M, Tome D, de Beaurepaire R. Long term treatment with olanzapine mixed with the food in male rats induces body fat deposition with no increase in body weight and no thermogenic alteration. Appetite 2006, 46:254-262.
    • (2006) Appetite , vol.46 , pp. 254-262
    • Minet-Ringuet, J.1    Even, P.C.2    Goubern, M.3    Tome, D.4    de Beaurepaire, R.5
  • 171
    • 8444253000 scopus 로고    scopus 로고
    • Clozapine blocks sympathetic and thermogenic reactions induced by orexin A in rat
    • Monda M, Viggiano A, Viggiano A, Fuccio F, De Luca V. Clozapine blocks sympathetic and thermogenic reactions induced by orexin A in rat. Physiol Res 2004, 53:507-513.
    • (2004) Physiol Res , vol.53 , pp. 507-513
    • Monda, M.1    Viggiano, A.2    Viggiano, A.3    Fuccio, F.4    De Luca, V.5
  • 173
    • 21244453135 scopus 로고    scopus 로고
    • Current therapy issues and unmet clinical needs in the treatment of schizophrenia: a review of the new generation antipsychotics
    • Lublin H, Eberhard J, Levander S. Current therapy issues and unmet clinical needs in the treatment of schizophrenia: a review of the new generation antipsychotics. Int Clin Psychopharmacol 2005, 20:183-198.
    • (2005) Int Clin Psychopharmacol , vol.20 , pp. 183-198
    • Lublin, H.1    Eberhard, J.2    Levander, S.3
  • 174
    • 2442509789 scopus 로고    scopus 로고
    • Managing atypical antipsychotic-associated weight gain: 12-month data on a multimodal weight control program
    • Menza M, Vreeland B, Minsky S, Gara M, Radler DR, Sakowitz M. Managing atypical antipsychotic-associated weight gain: 12-month data on a multimodal weight control program. J Clin Psychiatry 2004, 65:471-477.
    • (2004) J Clin Psychiatry , vol.65 , pp. 471-477
    • Menza, M.1    Vreeland, B.2    Minsky, S.3    Gara, M.4    Radler, D.R.5    Sakowitz, M.6
  • 175
    • 33947274677 scopus 로고    scopus 로고
    • Atypical antipsychotic drugs directly impair insulin action in adipocytes: effects on glucose transport, lipogenesis, and antilipolysis
    • Vestri HS, Maianu L, Moellering DR, Garvey WT. Atypical antipsychotic drugs directly impair insulin action in adipocytes: effects on glucose transport, lipogenesis, and antilipolysis. Neuropsychopharmacology 2007, 32:765-772.
    • (2007) Neuropsychopharmacology , vol.32 , pp. 765-772
    • Vestri, H.S.1    Maianu, L.2    Moellering, D.R.3    Garvey, W.T.4
  • 176
    • 27144450193 scopus 로고    scopus 로고
    • Antipsychotic drugs activate SREBP-regulated expression of lipid biosynthetic genes in cultured human glioma cells: a novel mechanism of action?
    • Ferno J, Raeder MB, Vik-Mo AO. Antipsychotic drugs activate SREBP-regulated expression of lipid biosynthetic genes in cultured human glioma cells: a novel mechanism of action?. Pharmacogenomics J 2005, 5:298-304.
    • (2005) Pharmacogenomics J , vol.5 , pp. 298-304
    • Ferno, J.1    Raeder, M.B.2    Vik-Mo, A.O.3    et al4
  • 177
    • 0037210111 scopus 로고    scopus 로고
    • Clozapine-induced weight gain predicts improvement in psychopathology
    • Meltzer HY, Perry E, Jayathilake K. Clozapine-induced weight gain predicts improvement in psychopathology. Schizophr Res 2003, 59:19-27.
    • (2003) Schizophr Res , vol.59 , pp. 19-27
    • Meltzer, H.Y.1    Perry, E.2    Jayathilake, K.3
  • 178
    • 0014879380 scopus 로고
    • Weight changes with schizophrenic psychosis and psychotropic drug therapy
    • Holden JM, Holden UP. Weight changes with schizophrenic psychosis and psychotropic drug therapy. Psychosomatics 1970, 11:551-561.
    • (1970) Psychosomatics , vol.11 , pp. 551-561
    • Holden, J.M.1    Holden, U.P.2
  • 179
    • 0036115924 scopus 로고    scopus 로고
    • Antipsychotic-induced weight gain and therapeutic response: a differential association
    • Czobor P, Volavka J, Sheitman B. Antipsychotic-induced weight gain and therapeutic response: a differential association. J Clin Psychopharmacol 2002, 22:244-251.
    • (2002) J Clin Psychopharmacol , vol.22 , pp. 244-251
    • Czobor, P.1    Volavka, J.2    Sheitman, B.3    et al4
  • 180
    • 34848827473 scopus 로고    scopus 로고
    • Changes in serum lipids, independent of weight, are associated with changes in symptoms during long-term clozapine treatment
    • Procyshyn RM, Wasan KM, Thornton AE. Changes in serum lipids, independent of weight, are associated with changes in symptoms during long-term clozapine treatment. J Psychiatry Neurosci 2007, 32:331-338.
    • (2007) J Psychiatry Neurosci , vol.32 , pp. 331-338
    • Procyshyn, R.M.1    Wasan, K.M.2    Thornton, A.E.3    et al4
  • 181
    • 28644433423 scopus 로고    scopus 로고
    • Course and predictors of weight gain in people with first-episode psychosis treated with olanzapine or haloperidol
    • Zipursky RB, Gu H, Green AI. Course and predictors of weight gain in people with first-episode psychosis treated with olanzapine or haloperidol. Br J Psychiatry 2005, 187:537-543.
    • (2005) Br J Psychiatry , vol.187 , pp. 537-543
    • Zipursky, R.B.1    Gu, H.2    Green, A.I.3    et al4
  • 182
    • 34548137741 scopus 로고    scopus 로고
    • Effectiveness, safety, and tolerability of ziprasidone for treating schizophrenia patients undergoing usual care: a 12-month, open-label, flexible-dose, naturalistic observational trial
    • Ratner Y, Gibel A, Yorkov V, Ritsner MS. Effectiveness, safety, and tolerability of ziprasidone for treating schizophrenia patients undergoing usual care: a 12-month, open-label, flexible-dose, naturalistic observational trial. Prog Neuropsychopharmacol Biol Psychiatry 2007, 31:1401-1409.
    • (2007) Prog Neuropsychopharmacol Biol Psychiatry , vol.31 , pp. 1401-1409
    • Ratner, Y.1    Gibel, A.2    Yorkov, V.3    Ritsner, M.S.4
  • 183
    • 33748439003 scopus 로고    scopus 로고
    • Intake of sugar-sweetened beverages and weight gain: a systematic review
    • Malik VS, Schulze MB, Hu FB. Intake of sugar-sweetened beverages and weight gain: a systematic review. Am J Clin Nutr 2006, 84:274-288.
    • (2006) Am J Clin Nutr , vol.84 , pp. 274-288
    • Malik, V.S.1    Schulze, M.B.2    Hu, F.B.3
  • 184
    • 43749104014 scopus 로고    scopus 로고
    • Pharmacological management of atypical antipsychotic-induced weight gain
    • Baptista T, Elfakih Y, Uzcategui E. Pharmacological management of atypical antipsychotic-induced weight gain. CNS Drugs 2008, 22:477-495.
    • (2008) CNS Drugs , vol.22 , pp. 477-495
    • Baptista, T.1    Elfakih, Y.2    Uzcategui, E.3    et al4


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