Central infusion of histamine reduces fat accumulation and upregulates UCP family in leptin-resistant obese mice

Diabetes

Volumn 50, Issue 2, 2001, Pages 376-384

  Masaki, Takayuki ^a   Yoshimatsu, Hironobu ^a   Chiba, Seiichi ^a   Watanabe, Takeshi ^b   Sakata, Toshiie ^a  

^a OITA UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; HISTAMINE; HISTAMINE H1 RECEPTOR; INSULIN; LEPTIN; UNCOUPLING PROTEIN 3;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY FAT; BODY WEIGHT; CALORIC INTAKE; CONTROLLED STUDY; ENERGY BALANCE; ENERGY EXPENDITURE; FOOD INTAKE; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; HYPOTHALAMUS; INSULIN BLOOD LEVEL; INSULIN TOLERANCE TEST; LIPID STORAGE; MALE; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; SUBCUTANEOUS FAT;

EID: 0035140171     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.50.2.376     Document Type: Article

References (44)

1. The deadly quartet: Upper-body obesity, glucose intolerance, hypertriglyceridemia, and hypertension
2. Positional cloning of the mouse obese gene and its human homologue
3. Weight-reducing effects of the plasma protein encoded by the obese gene
4. Effects of the obese gene product on body weight regulation in ob/ob mice
5. Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks
6. Thermogenic mechanism in brown fat
7. Uncoupling protein-2: A novel gene linked to obesity and hyperinsulinemia
8. Uncoupling protein-3: A new member of the mitochondrial Carder family with tissue-specific expression
9. UCP3: An uncoupling protein homologue expressed preferentially and abundantly in skeletal muscle and brown adipose tissue
10. Streptozotoxin treatment upregulates uncoupling protein 3 gene in the rat heart
11. Induction by leptin of uncoupling protein-2 and enzymes of fatty acid oxidation
12. Enhanced expression of uncoupling protein 2 gene in rat white adipose tissue and skeletal muscle following chronic treatment with thyroid hormone
13. Tumor necrosis factor-α regulates in vivo expression of the rat UCP family differentially
14. Chronic central leptin infusion enhances insulin-stimulated glucose metabolism and favors the expression of uncoupling protein expression and energy expenditure
15. Unraveling the central nervous system pathways underlying responses to leptin
16. Leptin increases hypothalamic pro-opiomelanocortin mRNA expression in the rostral arcuate nucleus
17. Involvement of agouti-related protein, an endogenous antagonist of hypothalamic melanocortin receptor, in leptin action
18. Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice
19. Corticotropin releasing hormone neurons in the paraventricular nucleus are direct targets for neuropeptide Y neurons in the arcuate nucleus: An anterograde tracing study
20. Effects of leptin on corticotropin-releasing factor (CRF) synthesis and CRF neuron activation in the paraventricular hypothalamic nucleus of obese (ob/ob) mice
21. Orexins and orexin receptors: A family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior
22. Functional interactions between melanin-concentrating hormone, neuropeptide Y, and anorectic neuropeptides in the rat hypothalamus
23. Decreased cerebrospinal-fluid/serum leptin ratio in obesity: A possible mechanism for leptin resistance
24. Cerebrospinal fluid leptin levels: Relationship to plasma levels and to adiposity in humans
25. Leptin levels reflect body lipid content in mice: Evidence for diet-induced resistance to leptin action
26. Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
27. Leptin not impressive in clinical trial
28. Evidence that the diabetes gene encodes the leptin receptor: Identification of a mutation in the leptin receptor gene in db/db mice
29. A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction
30. Diet-induced obese mice develop peripheral, but not central, resistance to leptin
31. Hypothalamic neuronal histamine as a target of leptin action on feeding behavior in the central nervous system
32. Hypothalamic neuronal histamine: Implication of its homeostatic control of energy metabolism
33. 1-receptor in the rat ventromedial hypothalamus and feeding elicitation
34. Hypothalamic sites of neuronal histamine action on food intake by rats
35. Hypothalamic neuronal histamine modulates physiological responses induced by interleukin-1 beta
36. Neuronal glucoprivation enhances hypothalamic histamine turnover in rats
37. A physiological role of brain histamine during energy deficiency
38. Lipolytic responses induced by intracerebroventricular administration of histamine in the rat
39. 1 receptors
40. Histamine lipolysis. I. Changes in the free fatty acid levels of dog plasma after intravenous infusion of histamine
41. Hypothalamic regulation of lipid metabolism in the rat: Effect of hypothalamic stimulation on lipolysis
42. Effect of CL-316,243, a thermogenic beta 3-agonist, on energy balance and brown and white adipose tissues in rots
43. Effects of nonesterified fatty acid availability on tissue-specific glucose utilization in rats in vivo
44. Differential regulation of mouse uncoupling proteins among brown adipose tissue, white adipose tissue, and skeletal muscle in chronic beta 3 adrenergic receptor agonist treatment