Long-term activation of TLR3 by Poly(I:C) induces inflammation and impairs lung function in mice

Respiratory Research

Volumn 10, Issue , 2009, Pages

  Stowell, Nicole C ^a   Seideman, Jonathan ^a   Raymond, Holly A ^a   Smalley, Karen A ^a   Lamb, Roberta J ^a   Egenolf, Devon D ^a   Bugelski, Peter J ^a   Murray, Lynne A ^a   Marsters, Paul A ^a   Bunting, Rachel A ^a   Flavell, Richard A ^b   Alexopoulou, Lena ^c   San Mateo, Lani R ^a   Griswold, Don E ^a   Sarisky, Robert T ^a   Mbow, M Lamine ^a,d   Das, Anuk M ^a  

^a CENTOCOR INC   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c CENTRE D IMMUNOLOGIE DE MARSEILLE LUMINY   (France)

^d GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON INDUCIBLE PROTEIN 10; GRANULOCYTE COLONY STIMULATING FACTOR RECEPTOR; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; METHACHOLINE; POLYINOSINIC POLYCYTIDYLIC ACID; RANTES; TOLL LIKE RECEPTOR 3; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; TLR3 PROTEIN, MOUSE;

AIRWAY RESISTANCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY PLETHYSMOGRAPHY; BRONCHIOLE; CELL INFILTRATION; CONTROLLED STUDY; FEMALE; HISTOPATHOLOGY; KNOCKOUT MOUSE; LUNG ALVEOLUS EPITHELIUM; LUNG DISEASE; LUNG FUNCTION; LUNG INTERSTITIUM; MONONUCLEAR CELL; MOUSE; NEUTROPHIL; NONHUMAN; PNEUMONIA; RECEPTOR UPREGULATION; ANIMAL; C57BL MOUSE; CELL LINE; CHEMICALLY INDUCED DISORDER; GENETICS; HUMAN; INFLAMMATION; LUNG FUNCTION TEST; MOUSE MUTANT; PATHOPHYSIOLOGY; PHYSIOLOGY; PLETHYSMOGRAPHY; SECRETION;

ANIMALS; CELL LINE; CYTOKINES; FEMALE; HUMANS; INFLAMMATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PLETHYSMOGRAPHY; POLY I-C; RESPIRATORY FUNCTION TESTS; TOLL-LIKE RECEPTOR 3;

EID: 70249120405     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/1465-9921-10-43     Document Type: Article

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