Synthetic double-stranded RNA induces multiple genes related to inflammation through Toll-like receptor 3 depending on NF-κB and/or IRF-3 in airway epithelial cells

Clinical and Experimental Allergy

Volumn 36, Issue 8, 2006, Pages 1049-1062

  Matsukura, S ^a   Kokubu, F ^a   Kurokawa, M ^a   Kawaguchi, M ^a   Ieki, K ^a   Kuga, H ^a   Odaka, M ^a   Suzuki, S ^a   Watanabe, S ^a   Takeuchi, H ^a   Kasama, T ^a   Adachi, M ^a  

^a SHOWA UNIVERSITY   (Japan)

Author keywords

dsRNA; Epithelial cells; IRF3; NF B; TLR3

Indexed keywords

DOUBLE STRANDED RNA; EPITHELIAL DERIVED NEUTROPHIL ACTIVATING FACTOR 78; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERFERON REGULATORY FACTOR 3; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; MONOCLONAL ANTIBODY; POLYINOSINIC POLYCYTIDYLIC ACID; PROTEIN; PROTEIN GRO ALPHA; RANTES; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR 3; UNCLASSIFIED DRUG;

ARTICLE; BRONCHUS; CELL SURFACE; CELL TYPE; CONTROLLED STUDY; EPITHELIUM CELL; FLOW CYTOMETRY; GENE EXPRESSION; GENE INDUCTION; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLAMMATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; RESPIRATORY SYSTEM; SIGNAL TRANSDUCTION; UPREGULATION;

ANTIBODIES, MONOCLONAL; ANTIVIRAL AGENTS; BRONCHI; CELL LINE, TRANSFORMED; CELLS, CULTURED; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITHELIAL CELLS; FLOW CYTOMETRY; GENE EXPRESSION; HUMANS; INTERFERON REGULATORY FACTOR-3; NF-KAPPA B; POLY I-C; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TOLL-LIKE RECEPTOR 3; UP-REGULATION; VIRUS DISEASES;

EID: 33746801581     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2006.02530.x     Document Type: Article

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