The cytosolic half of helix III forms the substrate exit route during permeation events of the sodium/bile acid cotransporter ASBT

Biochemistry

Volumn 48, Issue 36, 2009, Pages 8528-8539

  Hussainzada, Naissan ^a   Da Silva, Tatiana Claro ^a   Swaan, Peter W ^a  

^a UNIVERSITY OF MARYLAND   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING REAGENTS; BILE ACID; CHOLESTEROL HOMEOSTASIS; CYTOSOLIC; MEMBRANE PROTEINS; MOLECULAR MECHANISM; SEQUENCE ALIGNMENTS; STRUCTURAL IMPORTANCE; SUBSTRATE BINDING; SUBSTRATE KINETICS; SURFACE EXPRESSION; TRANSMEMBRANE HELICES; TRANSPORT ACTIVITY; TRANSPORT CYCLE;

ACIDS; BODY FLUIDS; HYDROCARBONS; SODIUM;

SUBSTRATES;

APICAL SODIUM DEPENDENT BILE ACID TRANSPORTER; BILE ACID; COTRANSPORTER; CYSTEINE; TAUROCHOLIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CYTOSOL; HYDROPHILICITY; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MOTIF; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; TRANSIENT TRANSFECTION;

ALKYLATION; AMINO ACID SEQUENCE; ANIMALS; BILE ACIDS AND SALTS; CYSTEINE; CYTOSOL; HUMANS; MEMBRANE GLYCOPROTEINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; ORGANIC ANION TRANSPORTERS, SODIUM-DEPENDENT; PROTEIN STRUCTURE, SECONDARY; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; SODIUM; SUBSTRATE SPECIFICITY; SYMPORTERS;

EID: 70249083096     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi900616w     Document Type: Article

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